Single-stage electrospun innovative combination of polyurethane and neem oil: Synthesis, characterization and appraisal of blood compatibility

2018 ◽  
Vol 33 (6) ◽  
pp. 573-584 ◽  
Author(s):  
Mohan Prasath Mani ◽  
Saravana Kumar Jaganathan ◽  
Ahmad Zahran Khudzari ◽  
Rajasekar Rathanasamy ◽  
Praseetha Prabhakaran
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Contact Angle ◽  
Partial Thromboplastin Time ◽  
Blood Compatibility ◽  
Activated Partial Thromboplastin Time ◽  
The Novel ◽  
Neem Oil ◽  
Composite Patch ◽  
Scanning Electron

Wound healing is a complex process and it requires proper scaffolding for regeneration. An ideal scaffold should provide optimal environmental conditions in order to assist cellular attachment, proliferation and differentiation. In this work, a new composite based on polyurethane and neem oil was fabricated using one-step electrospinning technique. Fabricated composite patch along with the pristine polyurethane was characterized through scanning electron microscopy, Fourier transform and infrared spectroscopy, thermogravimetric analysis, contact angle measurement and atomic force microscopy. Moreover, the blood compatibility was evaluated using activated partial thromboplastin time, partial thromboplastin time and haemolysis assay. Scanning electron microscopy studies of composites revealed the existence of fibres with a smaller diameter (635  ± 105 nm) compared to the pristine polyurethane (969 ± 217 nm). Fourier transform and infrared analysis revealed the formation of hydrogen bond and peak shifting characteristics confirming the interaction of the neem oil with the polyurethane. Contact angle analysis showed the decrease in contact angle indicating the hydrophilic nature of the fabricated patch compared to pristine polyurethane. Thermal gravimetric analysis depicted the better thermal stability of the novel composite patch due to the existence of neem oil in the pristine polyurethane. The presence of neem oil in polyurethane matrix also resulted in an increase in the surface roughness as observed in the AFM analysis. The novel composite patch showed an ability to reduce the thrombogenicity and promoting the anticoagulant nature signified by blood compatibility assays like activated partial thromboplastin time and partial thromboplastin time. Finally, the haemolytic percentage of the fabricated composite (1%) was found to be reduced compared to control (2.733%) indicating better blood compatibility and safety with the red blood cells. Following the results, the fabricated patches offered enhanced physicochemical and blood compatible nature making it as a promising candidate for wound healing application.

Influence of the Treatment with Sulfuric Acid on Adhesion of Natural Rubber and Cast Polyurethane Elastomers

2012 ◽  
Vol 452-453 ◽  
pp. 86-90 ◽  
Author(s):  
Zhi Yi Zhang ◽  
Hui Jun Niu ◽  
Jia Jia Zhang ◽  
Yan Yun Cui
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Contact Angle ◽  
Sulfuric Acid ◽  
Natural Rubber ◽  
Angle Measurement ◽  
Polyurethane Elastomers ◽  
Adhesion Properties ◽  
Rubber Surface ◽  
Scanning Electron

In this study, natural rubber (NR) was treated with sulfuric acid to improve its adhesion properties to polar polymer. T-peel strength tests, scanning electron microscopy, contact-angle measurement (water), Energy Dispersive X-ray Detector were used to analyze the nature of the NR surface modifications which were carried out with sulfuric acid. A noticeable decrease in contact angle was observed on the rubber surface by contact-angle measurements which can be ascribed to the increase of oxidized moieties on the rubber surface. EDX revealed that oxidized moieties were created through treatment with sulfuric acid. The surface modification and mode of bond failure were studied by scanning electron microscopy (SEM). Immersion in sulfuric acid for 15min produced the maximum adhesion strength (10kN/m) and produced a mixed failure mode (interface & rubber failure in the rubber). Treatment with sulfuric acid produced improved wettability as well as chemical (surface oxidation) and morphological modifications (roughness) of the rubber surface.

scholarly journals Preparation and Characterization of K-Carrageenan/Nanosilica Biocomposite Film

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Lokesh R. Rane ◽  
Niranjan R. Savadekar ◽  
Pravin G. Kadam ◽  
Shashank T. Mhaske
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Contact Angle ◽  
Tensile Strength ◽  
Water Vapour ◽  
Transmission Rate ◽  
Composite Films ◽  
Tensile Modulus ◽  
Water Vapour Transmission Rate ◽  
Scanning Electron

The purpose of this study is to improve the performance properties of K-carrageenan (K-CRG) by utilizing nanosilica (NSI) as the reinforcing agent. The composite films were prepared by solution casting method. NSI was added up to 1.5% in the K-CRG matrix. The prepared films were characterized for mechanical (tensile strength, tensile modulus, and elongation at break), thermal (differential scanning calorimetry, thermogravimetric analysis), barrier (water vapour transmission rate), morphological (scanning electron microscopy), contact angle, and crystallinity properties. Tensile strength, tensile modulus, and crystallinity were found to have increased by 13.8, 15, and 48% whereas water vapour transmission rate was found to have decreased by 48% for 0.5% NSI loaded K-CRG composite films. NSI was found to have formed aggregates for concentrations above 0.5% as confirmed by scanning electron microscopy. Melting temperature, enthalpy of melting, and degradation temperature of K-CRG increased with increase in concentration of NSI in K-CRG. Contact angle also increased with increase in concentration of NSI in K-CRG, indicating the decrease in hydrophilicity of the films improving its water resistance properties. This knowledge of the composite film could make beneficial contributions to the food and pharmaceutical packaging applications.

Super-Hydrophobic Surfaces Improve Corrosion Resistance of Fe3Al-Type Intermetallic in Seawater

2008 ◽  
Vol 47-50 ◽  
pp. 173-176 ◽  
Author(s):  
Tao Liu ◽  
Kin Tak Lau ◽  
Shou Gang Chen ◽  
Sha Cheng ◽  
Yan Sheng Yin
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Contact Angle ◽  
Corrosion Resistance ◽  
Electrochemical Impedance ◽  
Hydrophobic Surface ◽  
Contact Angle Measurement ◽  
Angle Measurement ◽  
Atomic Force ◽  
Scanning Electron

A novel super-hydrophobic film was prepared by myristic acid (CH3(CH2)12COOH) chemically adsorbed onto the polyethyleneimine (PEI) coated Fe3Al-type intermetallic wafer. The film character and structure were probed with contact angle measurement, scanning electron microscopy (SEM) and atomic force microscope (AFM). The results suggest that the structure of the film is similar to lotus and the seawater contact angle is larger than 150◦. Moreover, the corrosion resistances of untreated and modified samples in seawater were investigated by electrochemical impedance spectroscopy (EIS). Experimental results show that the corrosion rate of Fe3Al-type intermetallic with super-hydrophobic surface decreases dramatically because of its special microstructure.

scholarly journals Anti-Foulant Ultrafiltration Polymer Composite Membranes Incorporated with Composite Activated Carbon/Chitosan and Activated Carbon/Thiolated Chitosan with Enhanced Hydrophilicity

Membranes ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 827
Author(s):  
Syeda Samia Nayab ◽  
M. Asad Abbas ◽  
Shehla Mushtaq ◽  
Bilal Khan Niazi ◽  
Mehwish Batool ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Contact Angle ◽  
Activated Carbon ◽  
Bovine Serum Albumin ◽  
Bovine Serum ◽  
Carbon Composite ◽  
Flux Rate ◽  
Thiolated Chitosan ◽  
Scanning Electron

A rapid increase in population worldwide is giving rise to the severe problem of safe drinking water availability, necessitating the search for solutions that are effective and economical. For this purpose, membrane technology has shown a lot of promise but faces the challenge of fouling, leading to a reduction in its lifetime. In this study, ultrafiltration polyethersulfone membranes were synthesized in two different concentrations, 16% wt. and 20% wt., using the phase inversion method. Chitosan and activated carbon were incorporated as individual fillers and then as composites in both the concentrations. A novel thiolated chitosan/activated carbon composite was introduced into a polyethersulfone membrane matrix. The membranes were then analyzed using Attenuated Total Reflection–Fourier-Transform Infrared spectroscopy (ATR-FTIR), Scanning Electron Microscopy (SEM), optical profilometry, gravimetric analysis, water retention, mechanical testing and contact angle. For membranes with the novel thiolated chitosan/activated carbon composite, Scanning Electron Microscopy micrographs showed better channels, indicating a better permeability possibility, reiterated by the flux rate results. The flux rate and bovine serum albumin flux were also assessed, and the results showed an increase from 105 L/m2h to 114 L/m2h for water flux and the antifouling determined by bovine serum albumin flux increased from 23 L/m2h to 51 L/m2h. The increase in values of water uptake from 22.84% to 76.5% and decrease in contact angle from 64.5 to 55.7 showed a significant increase in the hydrophilic character of the membrane.

scholarly journals Hydrophobically modified cotton fabric assisted separation of oil-water mixture

2021 ◽  
Author(s):  
Neha Bhatt ◽  
Abhilasha Mishra ◽  
Rekha Goswami
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Contact Angle ◽  
Particle Size ◽  
Free Energy ◽  
Cotton Fabric ◽  
Water Mixture ◽  
Mixture Separation ◽  
Oil Water ◽  
Scanning Electron

Abstract Superhydrophobic-superoleophilic fabrics were prepared and evaluated for oil-water mixture separation efficiencies. The nano-TiO2 and nano- SiO2 based coatings were done on the surface of the cotton fabric to create nanoscale roughness over the surface which was further modified by low energy material 1, 1, 3, 3- Hexamethyldisilazane (HMDS) and, polydimethylsiloxane (PDMS). Particle size and stability of prepared sol were characterized by particle size analysis and zeta potential. Coated cotton fabric samples were characterized by contact angle, contact angle hesteresis and surface free energy for its hydrophobic nature. Surface morphology was studied by scanning electron microscopy (SEM). The coated fabrics were found hydrophobic with low surface free energy values. The maximum contact angle was found 133° and lowest contact angle hysteresis was 5°. Scanning electron microscopy (SEM) confirmed the appearance of nanoscale surface roughness after coating of sols on cotton fabric. The average particle size and zeta potential values of silica sol was 61 nm and 137 mv whereas for titania sol it was found 344 nm and 200 mv respectively. The oil/water separation efficiency of coated fabric was also observed by different oil-water mixture. The coatings were found hydrophobic in nature and seem to be very useful for water/oil mixture separation.

scholarly journals Silver Nanoparticles: Green Synthesis, Characterization, Blood Compatibility and Protoscolicidal Efficacy against Echinococcus granulosus

2021 ◽  
Vol 41 (03) ◽  
pp. 393-399
Author(s):  
Parwin Jalal Jalil
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Silver Nanoparticles ◽  
Echinococcus Granulosus ◽  
Blood Compatibility ◽  
Ag Nps ◽  
X Ray ◽  
Hydatid Fluid ◽  
Scanning Electron

Spillage of protoscoleces within hydatid fluid during surgery for hydatid cyst is the main reason for its recurrence. Therefore, to inactivate the protoscoleces, various scolicidal substances have been tested. However, novel and more efficient agents are needed owing to several associated complications. This study focused on the effects of green synthetic Silver Nanoparticles (AgNPs) from Zizyphus spina- christi leaves on Echinococcus granulosus protoscoleces. Also, to evaluate the blood compatibility of Ag NPs. The Ag NPs were identified by ultraviolet-visible (UV-Visible) spectrophotometer, X-ray diffraction (XRD), Scanning electron microscopy imaging, and Energy-dispersive X-ray spectroscopy (EDX). Hydatid fluid was aspirated aseptically from cysts of infected sheep liver. The protoscoleces were exposed to Ag NPs at several concentrations. Also, scanning electron microscopy for ultrastructural changes and in vitro erythrocytes lysis was performed. The Ag NPs were spherical; the particles' size reached 50 nm, and presented a surface plasmon peak around 460 nm. The current study's findings indicated the powerful in vitro scolicidal efficacy of the green biosynthesized AgNPs. Several morphological alterations were observed on the protoscoleces by optical and scanning electron microscopy. Lysis of RBCs at different doses of Ag NPs was significantly (P≤0.05) less than the positive control value, thus proposing its biocompatibility. This work suggests that chemicals like polyphenols present in the extract of Z. spina- christi act as reducing and stabilizers agents to create Ag NPs Nevertheless, further investigations are needed to investigate the Ag NPs scolicidial effects in animal models.

scholarly journals The Removal of HBV in Plasma by Extracorporeal Immunoadsorption from Plasma: A Potential Therapy of Hepatitis B Patients

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Zhenwei Han ◽  
Xuan Lu ◽  
Yiping Tang ◽  
Yuanyuan Yang ◽  
Qiuchen Liu ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Monoclonal Antibody ◽  
Time Dependent ◽  
The Novel ◽  
Plasma Samples ◽  
Novel Therapy ◽  
Real Time Quantitative Pcr ◽  
Therapy Option ◽  
Scanning Electron

Objective. To establish a novel HBV specific immunoadsorbent for the removing of HBV particles.Methods. The anti-HBsAg monoclonal antibody was immobilized on sepharose beads to produce a sepharose anti-HBs column. Then the immunoadsorbent was evaluated and characterized by scanning electron microscopy. In addition, time-dependent effects of the eradication capacity of anti-HBsAg functionalized sepharose beads against HBV were investigated.Results. Proposed immunoadsorbents exhibited a favorable biocompatibility as well as specificity. With the optimized recycle time, the decontamination performance of HBV particles and quantity of HBsAg were assessed either by real-time quantitative PCR or ELISA, which showed that the immunoadsorbent could remove approximately 90% of the HBV and 90% of the HBsAg from human plasma samples.Conclusions. All these results indicated that the novel immunoadsorbent could effectively remove HBV particles and likely serve as a novel therapy option or at least supplementary for the treatment regimen of HBV.

Super-Hydrophobic Properties of Unitary Structure

2014 ◽  
Vol 924 ◽  
pp. 212-216
Author(s):  
Jing Li ◽  
Cheng Yu Xu ◽  
Feng Du ◽  
Xian Li Liu ◽  
Hua Dong Yu
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Contact Angle ◽  
Lower Surface ◽  
Hydrophobic Property ◽  
Hydrophobic Properties ◽  
Lotus Leaf ◽  
Structure Characteristics ◽  
Biomimetic Surfaces ◽  
Scanning Electron

In this paper, the unitary structure characteristics and the super-hydrophobic properties of the lower surface of the lotus leaf and artificial biomimetic surfaces were investigated through scanning electron microscopy, field emission scanning electron microscopy, x-ray photoelectron spectroscopy and contact angle measurement. The measurement of wettability showed that artificial unitary structure surfaces modified with the lower surface energy material exhibit a super-hydrophobic property with a water contact angle of about 150°. The artificial structure characteristics and the super-hydrophobic properties are similar to those on the lower surface of the lotus leaf. The contribution mechanism of the unitary structure on the hydrophobic property was discussed for the surfaces of the lotus leaf and artificial biomimetic surfaces based on the Cassis-Baxter model.

Modification and characterization of polysulfone films by ionizing radiation (gamma-rays) with enhanced hydrophilicity

MRS Advances ◽  
2018 ◽  
Vol 3 (63) ◽  
pp. 3833-3837
Author(s):  
Israel Fredy Sánchez-Salinas ◽  
Javier Illescas ◽  
Claudia Rosario Muro-Urista ◽  
Guillermina Burillo ◽  
María del Carmen Díaz Nava
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Contact Angle ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Reaction Time ◽  
Gamma Rays ◽  
Poly Vinyl Alcohol ◽  
Scanning Electron

AbstractPolysulfone (Pfu) films were modified by grafting poly(vinyl alcohol) (PVA) by the oxidative pre-irradiation technique. To achieve this modification, some parameters were modified such as the radiation dose, the concentration of PVA, the temperature and the reaction time. It was found that the grafted films with 12% presented a greater grafting percentage (0.86%). The modified films were characterized by means of the contact angle, Fourier transform infrared spectroscopy (FTIR-ATR) and scanning electron microscopy (SEM) techniques.

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