Quality of Life of People With Alzheimer Disease: Comparison Between Dyads Degree of Kinship

2020 ◽  
pp. 089198872091552
Author(s):  
Marcela Moreira Lima Nogueira ◽  
Jose Pedro Simões Neto ◽  
Marcia Cristina Nascimento Dourado
Keyword(s):  
Quality Of Life ◽  
Alzheimer Disease ◽  
Linear Regression ◽  
Multivariate Regression ◽  
Self Report ◽  
Regression Analyses ◽  
Burden Of Care ◽  
Significant Difference ◽  
Better Than

The quality of life (QoL) of people with Alzheimer disease (PwAD) may be influenced by the type of relationship between carer and the PwAD. Dyads of 98 PwAD/carers (N = 49 spouse-carers; N = 49 nonspouses carers) were measured about QoL, cognition, dementia severity, awareness of disease, functionality, depression, anxiety, and burden of care. Univariate and multivariate regression analyses were conducted to identify the factors that influenced the spouse and nonspouse self-report PwAD QoL (PQOL) and to compare carers’ ratings of PwAD QoL (C-PQOL). The total score of QoL for spouse and nonspouse PwAD showed no significant difference ( P = .29). The linear regression demonstrated that higher awareness of disease was significantly related to spouse PQOL ( P = .001). Nonspouse PQOL was negatively related to lower depression ( P = .007). The total score of QoL for spouse and nonspouse C-PQOL showed no significant difference ( P = .14). The linear regression demonstrated that depression of spouse-PwAD ( P < .001) and burden of care ( P = .001) were negatively related to spouse-dyads’ C-PQOL. The nonspouse-dyads C-PQOL was negatively related to depression of nonspouse-PwAD ( P < .001), awareness of disease ( P = .001), and the mood of the carer ( P = .01). Spouse and nonspouse PwAD evaluate PQOL better than carers (C-PQOL). No significant difference was found in the total PQOL and C-PQOL of spouse and nonspouse, but dyads evaluated differently about what is important to assess QoL.

Quality of life in multiple sclerosis patients in Spain

2002 ◽  
Vol 8 (6) ◽  
pp. 527-531 ◽  
Author(s):  
C-H Chang ◽  
D Cella ◽  
O Fernández ◽  
G Luque ◽  
P de Castro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Well Being ◽  
Cross Sectional Study ◽  
Self Report ◽  
Regression Analyses ◽  
Cross Sectional ◽  
Scale Scores ◽  
Multiple Sclerosis Patients

Objective: The cross-sectional study evaluated the psychometric properties of the Functional Assessment of Multiple Sclerosis (FAMS) Spanish version and its use in measuring quality of life (QOL) of multiple sclerosis (MS) patients in Spain. Methods: The FAMS is a factorially derived self-report scale designed to assess six primary aspects of QOL of patients with MS: Mobility, Symptoms, Emotional Well-Being, General Contentment, Thinking and Fatigue, and Family/Social Well-Being. Its Spanish translated version was used to assess QOL of 625 MS patients recruited in an outpatient clinic setting from 58 hospitals in Spain. Internal consistency of the Spanish FAMS was evaluated. Multiple regression analyses were performed to identify significant predictors from demographic, clinical and treatment characteristics, and Kurtzke Expanded Disability Status Scale (EDSS) scores in predicting FAMS scale scores. Results: Most of the patients are females (66%), and 74% were of the relapsing-remitting (RR) clinical subtype. Cronbach’s alpha coefficients were high (range=0.78-0.96), indicating subscale homogeneity comparable to that of the original English version. Linear multivariate regression analyses revealed that the EDSS is a dominant variable in predicting all the FAMS subscales, especially mobility (R2=0.51) and the total scores. Conclusions: The Spanish FAMS is a psychometrically valid instrument that allows clinicians and clinical researchers the ability to measure the QOL concerns of MS patients in Spain.

scholarly journals Association between Disease-Specific Quality of Life and Complementary Medicine Use in Patients with Rhinitis in Taiwan: A Cross-Sectional Survey Study

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Malcolm Koo ◽  
Kai-Li Liang ◽  
Rong-San Jiang ◽  
Hsin Tsao ◽  
Yueh-Chiao Yeh
Keyword(s):  
Quality Of Life ◽  
Linear Regression ◽  
Medical Condition ◽  
Survey Study ◽  
Regression Analyses ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Female Sex ◽  
Disease Specific

Rhinitis is a common medical condition and can seriously impact patients’ quality of life. The objective of this study was to investigate the association between disease-specific quality of life and use of complementary and alternative medicine (CAM) modalities among Taiwanese rhinitis patients. A cross-sectional survey was undertaken at the outpatient department of otolaryngology in a medical center in Taiwan. Sociodemographic information, disease-specific quality of life (Chinese version of the 31-item Rhinosinusitis Outcome Measure, CRSOM-31), and previous use of CAM modalities for treatment of rhinitis of the patients were ascertained. Factor analysis was performed to reduce the number of CAM modalities. The resulting factors were analyzed for their association with CRSOM-31 score using linear regression analyses. Results from the multiple linear regression analyses indicated that Factor 1 (traditional Chinese medicine), Factor 2 (mind-body modalities), Factor 3 (manipulative-based modalities), female sex, and smoking were significantly associated with a worse disease-specific quality of life. In conclusion, various CAM modalities, female sex, and smoking were independent predictors of a worse disease-specific quality of life in Taiwanese patients with rhinitis.

scholarly journals Recovering Quality of Life (ReQoL): a new generic self-reported outcome measure for use with people experiencing mental health difficulties

2018 ◽  
Vol 212 (1) ◽  
pp. 42-49 ◽  
Author(s):  
Anju Devianee Keetharuth ◽  
John Brazier ◽  
Janice Connell ◽  
Jakob Bue Bjorner ◽  
Jill Carlton ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Outcome Measures ◽  
Service User ◽  
Quantitative Methods ◽  
Outcome Measure ◽  
Well Being ◽  
Self Report ◽  
Better Than

BackgroundOutcome measures for mental health services need to adopt a service-user recovery focus.AimsTo develop and validate a 10- and 20-item self-report recovery-focused quality of life outcome measure named Recovering Quality of Life (ReQoL).MethodQualitative methods for item development and initial testing, and quantitative methods for item reduction and scale construction were used. Data from >6500 service users were factor analysed and item response theory models employed to inform item selection. The measures were tested for reliability, validity and responsiveness.ResultsReQoL-10 and ReQoL-20 contain positively and negatively worded items covering seven themes: activity, hope, belonging and relationships, self-perception, well-being, autonomy, and physical health. Both versions achieved acceptable internal consistency, test–retest reliability (>0.85), known-group differences, convergence with related measures, and were responsive over time (standardised response mean (SRM) > 0.4). They performed marginally better than the Short Warwick-Edinburgh Mental Well-being Scale and markedly better than the EQ-5D.ConclusionsBoth versions are appropriate for measuring service-user recovery-focused quality of life outcomes.Declaration of interestM.B. and J.Co. were members of the research group that developed the Clinical Outcomes in Routine Evaluation (CORE) outcome measures.

scholarly journals Long-term Outcomes in Adolescents and Adults with a Cleft Lip and/or palate: Esthetics, Employment and Functioning

2021 ◽  
Author(s):  
Cassandra Alighieri ◽  
Evelien D'haeseleer ◽  
Kim Bettens ◽  
Katrien Bonte ◽  
Hubert Vermeersch ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Well Being ◽  
Self Report ◽  
Control Group ◽  
Older Individuals ◽  
Significant Difference ◽  
Adolescents And Adults ◽  
The Impact

Abstract Background. To date, there seems to be no consensus on the long-term quality of life outcomes in patients living with a cleft of the lip and/or palate (CL/P) with regard to well-being and functioning. Some studies report a substantial influence of having a cleft while other studies report no influence of living with a cleft. The purpose of this study was to investigate the impact of living with a CL/P on esthetics, employment and functioning in Dutch-speaking adolescents and adults with a CL/P. Methods. 30 Patients with a CL/P (19 men and 11 women) were included in the study. The mean age of the participants was 26.93 years (SD = 11.688 years, range = 15 – 66 years). An age and gender matched control group was included consisting of 30 participants (19 men and 11 women) without a CL/P with a mean age of 26.87 years (SD = 11.729 years, range = 16-67 years). Esthetics, employment and functioning were assessed using different standardized self-report questionnaires. Results. No statistically significant difference in educational level, employment, monthly net income, marital status and having children was found between participants with and without a CL/P. In addition, the quality of life scores did not differ between the two groups. Within the group of individuals with a CL/P, the findings revealed that the proportion of participants who reported an influence of the CL/P on daily functioning, general well-being, social contacts, family life, applying for a job, work, education and leisure time differed by age. Older individuals experienced more influence of their CL/P compared to younger individuals. With regard to esthetics, the findings revealed that participants without a CL/P were less satisfied with the appearance of their jaws compared to participants with a CL/P. Conclusion. In general, the findings of our study revealed no significant differences between adolescents and adults with and without a CL/P with regard to employment and functioning. Considering age within the group of participants with a CL/P, however, the results demonstrated that older individuals were more likely to experience a negative impact of their cleft on well-being and functioning. These findings suggest that older individuals with a CL/P might benefit from additional socio-emotional support, for example peer contacts and support groups or psychological guidance. Longitudinal research on this topic is highly needed to determine possible fluctuations in the impact of living with a CL/P.

scholarly journals Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease

2022 ◽  
Vol 12 (1) ◽  
pp. 111
Author(s):  
Kristina Rosqvist ◽  
Anette Schrag ◽  
Per Odin ◽  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Linear Regression ◽  
Caregiver Burden ◽  
Male Patient ◽  
Late Stage ◽  
Informal Caregivers ◽  
Regression Analyses ◽  
Patient Gender

Parkinson’s disease (PD) is a chronic, progressive, neurodegenerative disease involving both motor and non-motor symptoms (NMS). In the late stage of the disease, Hoehn and Yahr (H&Y) stage IV-V, the symptomatology is often severe and patients become increasingly dependent on help in their daily life, resulting in an increased burden for the informal caregivers. To assess the implications of the caregiver burden, caregiver quality of life (QoL) was assessed in 74 informal caregivers to patients in late stage PD, by the Alzheimer’s Patient Partners Life Impact Questionnaire (APPLIQue), which has been found useful also in PD. The majority of caregivers were the spouse/partner. Individual items provided information on which aspects of caregiver burden were the most common, i.e., items: “feel guilty if not there (71% affirmed)”, “the situation wears me down” (65% affirmed) and “always on my mind” (61% affirmed). In simple linear regression analyses, male patient gender (p = 0.007), better cognition (p = 0.004), lower NMS burden (p = 0.012) and not being the partner (p = 0.022) were associated with better caregiver QoL. Multivariable linear regression analyses identified better cognition (p = 0.004) and male patient gender (p = 0.035) as independently associated with better informal caregiver QoL. Identifying and treating NMS as well as recognizing and alleviating caregiver burden seem essential to enhance QoL for both patients and caregivers in late stage PD.

Caregivers’ Perspectives of Quality of Life of People With Young- and Late-Onset Alzheimer Disease

2018 ◽  
Vol 31 (2) ◽  
pp. 76-83 ◽  
Author(s):  
Nathália R. S. Kimura ◽  
Maria Alice T. Baptista ◽  
Raquel L. Santos ◽  
Maria da Gloria Portugal ◽  
Aud Johannenssen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer Disease ◽  
Late Onset ◽  
Linear Regression Analysis ◽  
Age At Onset ◽  
Burden Of Care ◽  
Area Of Interest ◽  
Effective Interventions ◽  
Dementia Research

Background: Quality of life (QoL) is a growing area of interest in dementia research. This study aims to investigate the caregivers’ perspective about the QoL of people with young-onset Alzheimer disease (YOAD) and late-onset Alzheimer disease (LOAD). We also aim to investigate factors that might be associated to caregivers’ perspective in YOAD and LOAD. Methods: We included 110 people with Alzheimer disease (PwAD; 53 YOAD) and their primary caregivers. The PwAD completed assessments about their QoL and cognition. The caregivers provided information about the PwAD (demographics, QoL, ability to perform activities of daily living, mood, and dementia severity) and had burden of care assessed. Results: We did not find a difference in caregivers’ perspectives of PwAD QoL according to the age at onset. However, the linear regression analysis indicated that caregivers’ burden ( P < .01) and PwAD depressive symptoms ( P < .05) were significantly related to the caregivers’ perspective of YOAD QoL. Caregivers’ burden ( P < .01), years of education ( P < .05), and self-reported QoL ( P < .01) were significantly related to the caregivers’ perspective of LOAD QoL. Conclusions: The factors that drive the perceptions of caregivers of PwAD QoL may vary according to the age at onset. The study provides basic information on caregivers’ perspectives of PwAD QoL to create more effective interventions according to the age at onset.

ASSOCIATION BETWEEN NUTRITIONAL STATUS AND QUALITY OF LIFE IN (PRE)FRAIL COMMUNITY-DWELLING OLDER PERSONS

2016 ◽  
pp. 1-8
Author(s):  
E. LUGER ◽  
S. HAIDER ◽  
A. KAPAN ◽  
K. SCHINDLER ◽  
C. LACKINGER ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Linear Regression ◽  
Nutritional Status ◽  
Social Participation ◽  
Older Persons ◽  
Community Dwelling ◽  
World Health ◽  
Regression Analyses ◽  
World Health Organization Quality

Background: For developed countries, healthy aging is one of the challenges and the number of healthy life years and especially the quality of life (QoL) are important. Objective: This study aimed to assess the association between nutritional status and different domains of QoL in (pre)frail community-dwelling elders. Design: Baseline data from persons, who participated in a 12-week nutritional and physical training intervention program, conducted from September 2013 - July 2015. Setting: (Pre)frail community-dwelling elders living in Vienna, Austria. Participants: A total of 83 older persons living at home, 12 men and 71 women (86%) aged 65 to 98 years. Measurements: Structured interviews were conducted at participants’ homes. Mini Nutritional Assessment® long-form (MNA®-LF) was used to investigate the nutritional status. The QoL domains were assessed with the World Health Organization Quality of Life questionnaires. Simple and multiple linear regression analyses were performed to evaluate the association between nutritional status and QoL domains, adjusted for possible confounders. Results: 45% of the participants were at risk of malnutrition and 3% were malnourished. Compared to normal nourished people, persons who had an impaired nutritional status, significantly differed in the QoL domain ‘autonomy’ with mean (SD) scores of 50.0 (14.9) vs. 57.3 (13.7); p=0.022 and in the QoL domain ‘social participation’ with scores of 40.1 (13.6) vs. 47.0 (11.2); p=0.014, respectively. According to linear regression analyses, the MNA®-LF score was significantly associated with ‘overall QoL’ (β=0.26; p=0.016) and the QoL domains ‘physical health’ (β=0.23; p=0.036), ‘autonomy’ (β=0.27; p=0.015), and ‘social participation’ (β=0.28; p=0.013). Conclusions: There was a significant association between nutritional status and QoL in elderly (pre)frail community-dwelling people, in particular for the QoL domains ‘autonomy’ and ‘social participation’. However, it remains unclear whether malnutrition was the cause or the consequence, or it was mediated through a third possible factor e.g. the functional status.

scholarly journals Mental health status and quality of life in elderly patients with coronary heart disease

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e10903
Author(s):  
Min Tang ◽  
Song-Hao Wang ◽  
Hui-Lin Li ◽  
Han Chen ◽  
Xin-Yi Sun ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Linear Regression ◽  
Regression Analyses ◽  
Stepwise Linear Regression

Background Coronary heart disease (CHD) is the leading cause of morbidity and mortality among elderly individuals. Patients with CHD are at high risk for mental health disorders, and psychological issues may affect the quality of life (QoL) of these patients. Nevertheless, there is little evidence regarding the psychological issues and QoL of patients with CHD among the elderly population. This study aimed to investigate the relationship between comorbidities and mental status as well as QoL among elderly patients with CHD. Methods Overall, 216 patients were included in this cross-sectional, observational, single-center study. The demographics and clinical manifestations of the patients were collected from electronic medical records. All patients were interviewed using the Chinese version of Symptom Checklist 90 (SCL-90) to assess the mental health status and the World Health Organization Quality of Life-BREF questionnaire (WHOQOL-BREF) to assess the QoL. Results In total, 96 men and 120 women, with a mean age of 71.69 ±  8.30 years, were included. When controlling for the patients’ sex, marital status and stroke, multiple stepwise linear regression analyses suggested that for CHD patients, comorbid type 2 diabetes mellitus had the significant influence on average positive factors (Coef., 5.809; 95% CI [2.467–9.152] p = 0.001); when controlling for the patients’ sex, marital status and type 2 diabetes mellitus, multiple stepwise linear regression analyses suggested that for CHD patients, comorbid stroke had the significant influence on average positive factors (Coef., 8.680; 95% CI [4.826–12.534]; p < 0.001); when controlling for the patients’ sex, marital status, type 2 diabetes mellitus and stroke, multiple stepwise linear regression analyses suggested that for CHD patients, comorbid primary hypertension had the significant influence on phobic anxiety (Coef., 0.178; 95% CI [0.010–0.347]; p = 0.038). Conclusions For elderly CHD patients, comorbid type 2 diabetes mellitus and stroke were at risk for psychological problems and lower QoL. Our findings may guide patients and clinicians to make better decisions and achieve better outcomes.

Family Quality of Life and Its Correlates Among Parents of Children and Adults With Intellectual Disability

2019 ◽  
Vol 124 (2) ◽  
pp. 99-115 ◽  
Author(s):  
Thomas L. Boehm ◽  
Erik W. Carter
Keyword(s):  
Quality Of Life ◽  
Intellectual Disability ◽  
Linear Regression ◽  
Social Relationships ◽  
Family Quality Of Life ◽  
Regression Analyses ◽  
High Quality ◽  
Research And Practice ◽  
Relationship Factors

AbstractAll families, including those impacted by disability, desire and deserve opportunities for high quality of life. This study focused on family quality of life (FQOL) among 529 parents with children or adults with intellectual disability (ID). Parents reported moderate to high levels of FQOL satisfaction, with some variability across domains. We conducted hierarchical linear regression analyses to examine associations among FQOL and: (1) individual and family demographic factors, (2) religiosity/spirituality factors, and (3) relationship factors. Findings highlighted the significance of both informal (i.e., family, friends) and formal (i.e., professional) social relationships, as well as the relevance of spirituality/religiosity, as factors contributing to FQOL. We offer recommendations for research and practice aimed at enhancing FQOL of parents with children and adults who have ID.

scholarly journals Quality of Life Indicators in Patients Operated on for Breast Cancer in Relation to the Type of Surgery—A Retrospective Cohort Study of Women in Serbia

Medicina ◽  
2020 ◽  
Vol 56 (8) ◽  
pp. 402
Author(s):  
Predrag Kovačević ◽  
Snežana Miljković ◽  
Aleksandar Višnjić ◽  
Jefta Kozarski ◽  
Radmilo Janković
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Linear Regression ◽  
Multiple Linear Regression ◽  
World Health ◽  
Total Mastectomy ◽  
World Health Organization Quality ◽  
Significant Difference ◽  
Type Of Surgery

Background and objectives: Quality of life (QoL) after breast cancer surgery is an important public health issue. The aim of this study was to determine the relationship between the levels of perceived quality of life in patients operated on for breast cancer in relation to the type of surgery, using the standardized questionnaires. Materials and Methods: We assessed 425 women after surgery for breast cancer. The assessment included the application of the WHOQOL-bref (The World Health Organization Quality of Life-Bref), and FACT-B (Functional Assessment of Cancer Therapy-Breast) questionnaires. The statistical analysis of the data included multiple linear regression and correlation tests. Results: Multiple linear regression analysis found that education, existence of comorbidities, time elapsed since surgery, and type of surgery were significant predictors of overall quality of life. Women’s overall quality of life and general health has increased by 0.16 times for each subsequent year of surgery, and by 0.34 times for each subsequent higher education level. Breast-conserving surgery or mastectomy with breast reconstruction were statistically significant (β = 0.18) compared to total mastectomy. Conclusions: There is a significant difference in the quality of life perceived by patients in whom the breast has been preserved or reconstructed in relation to patients in whom total mastectomy has been performed.

Sign in / Sign up

Export Citation Format

Share Document