Biomarker evaluation of Greek adolescents’ exposure to secondhand smoke

2009 ◽  
Vol 29 (6) ◽  
pp. 459-466 ◽  
Author(s):  
CI Vardavas ◽  
MN Tzatzarakis ◽  
M. Plada ◽  
AM Tsatsakis ◽  
A. Papadaki ◽  
...  
Keyword(s):  
Secondhand Smoke ◽  
Healthy Lifestyle ◽  
Gas Chromatography Mass Spectrometry ◽  
Serum Cotinine ◽  
Public Places ◽  
School Based ◽  
Shs Exposure ◽  
Almost All ◽  
Biomarker Evaluation ◽  
Exposure To Secondhand Smoke

Exposure to secondhand smoke (SHS) is a significant threat to public health, and represents a danger for both the development and health status of children and adolescents. Taking the above into account, our aim was to quantify Greek adolescents’ exposure to SHS using serum cotinine levels. During 2006, 341 adolescents aged 13-17 were randomly selected from high schools in Heraklion and agreed to participate as part of the European Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study. Blood samples were drawn from a random sample of 106 adolescents, while serum cotinine/nicotine concentrations were measured by Gas Chromatography—Mass Spectrometry (GC-MS). The mean levels of serum cotinine and nicotine were calculated at 1.60 ± 2.18 ng/mL and 4.48 ± 4.00 ng/mL, respectively, while 97.7% of the non-smoker adolescents were found to have measureable levels of serum cotinine indicating exposure to SHS. The analysis revealed that their paternal (p = .001) and maternal smoking habits (p = .018) as also the existence of a younger brother or sister (p = .008) were the main modifiers of SHS exposure during adolescence. Conclusively, almost all of the measured Greek adolescents were exposed to SHS, even when their parents were non-smokers. This finding indicates the need for both community and school-based educational programmes as also the implementation of a comprehensive ban on smoking in public places.

Abstract 15034: Exposure to Secondhand Smoke is Associated With Increased Left Ventricular Mass

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Travis M Skipina ◽  
Bharathi Upadhya ◽  
Elsayed Z Soliman
Keyword(s):  
Secondhand Smoke ◽  
Left Ventricular ◽  
Nhanes Iii ◽  
P Value ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
Serum Cotinine ◽  
Lv Mass ◽  
Shs Exposure ◽  
Exposure To Secondhand Smoke

Background: Exposure to secondhand smoke (SHS), or passive smoking, has been associated with chronic hypertension. However, little is known about the relationship between SHS and left ventricular (LV) hypertrophy, the most common complication of hypertension and a manifestation of cardiac end-organ damage. Hypothesis: SHS exposure is independently associated with LV mass. Methods: This analysis included 4,982 non-smoker participants (age 60.8±13.6 years, 57.8% women, 77.7% whites) from the Third National Health and Nutrition Examination (NHANES-III). Non-smoking was defined by self-report and serum cotinine ≤ 10 ng/dL, a biomarker for tobacco exposure. SHS was defined as serum cotinine level >1 ng/dL. LV mass was estimated using an electrocardiographic model developed and applied in NHANES-III then validated in the Cardiovascular Health Study. Multivariable linear regression was used to examine the cross-sectional association between SHS exposure (vs. no exposure) with estimated LV mass. In similar models, we also examined the associations of LV mass across quartiles of serum cotinine (reference group, 1 st quartile) and in subgroups stratified by race, sex, and hypertension status. Results: About 9.8% (n=489) of the participants were exposed to SHS. Exposure to SHS was associated with an estimated 2.9 gram increase in LV mass, with a dose-response relationship between higher serum cotinine and LV mass ( Table ). These results were consistent in men and women (interaction p-value= 0.31), whites and non-whites (interaction p-value= 0.21), and those with and without hypertension (interaction p-value= 0.88) Conclusion: In a racially diverse sample of non-smokers, SHS is associated with increased LV mass with a dose-response relationship between level of exposure and LV mass. These findings underscore the harmful effect of passive smoking on the cardiovascular system and highlight the need for more restrictions on smoking in public areas.

scholarly journals Voluntary Smoke-Free Home Rules and Exposure to Secondhand Smoke in Poland: A National Cross-Sectional Survey

2020 ◽  
Vol 17 (20) ◽  
pp. 7502
Author(s):  
Mateusz Jankowski ◽  
Jarosław Pinkas ◽  
Wojciech S. Zgliczyński ◽  
Dorota Kaleta ◽  
Waldemar Wierzba ◽  
...  
Keyword(s):  
Secondhand Smoke ◽  
Home Rule ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Public Places ◽  
Private And Public ◽  
Shs Exposure ◽  
Nationally Representative ◽  
Private Homes ◽  
Exposure To Secondhand Smoke

Smoke-free policies have been shown to significantly reduce secondhand smoke (SHS) exposure in private and public places. The objectives of this study were to: (1) to assess the prevalence and characteristics of voluntary smoke-free home rules in Poland; and (2) assess the association of smoke-free rules with self-reported SHS exposure in private homes. A cross-sectional survey was conducted in September 2019 with a nationally representative sample of 1011 individuals aged 15 and over. Nationally, 66.1% of individuals had a 100% smoke-free home rule (78.9% of non-smokers and 18.6% of smokers; p < 0.001), while a further 24.6% had adopted a partial home smoking rule. SHS exposure in the home during past month was reported by 6.1% of respondents (11.5% of smokers and 4.5% of non-smokers; p < 0.001). The lowest level of SHS exposure (1.8%) was observed among respondents who had implemented a full smoke-free home rule. Non-smokers had higher odds of having adopted a total smoke-free home rule compared with smokers (aOR: 19.17; 95% CI: 12.89–28.50). Moreover, non-smokers had lower odds (aOR: 0.35; 95% CI: 0.20–0.61; p < 0.001) of self-reporting SHS smoke exposure at home. Although two-thirds of the Polish population have adopted a full smoke-free home rule in their homes, smokers continue to lag in adoption rates relative to non-smokers.

scholarly journals Secondhand Smoke Exposure in Public Places and Support for Smoke-Free Laws in Japan: Findings from the 2018 ITC Japan Survey

2020 ◽  
Vol 17 (3) ◽  
pp. 979 ◽  
Author(s):  
Genevieve Sansone ◽  
Geoffrey T. Fong ◽  
Gang Meng ◽  
Lorraine V. Craig ◽  
Steve S. Xu ◽  
...  
Keyword(s):  
Secondhand Smoke ◽  
Smoking Prevalence ◽  
Tobacco Product ◽  
Smoking Bans ◽  
Public Places ◽  
Total N ◽  
The Public ◽  
Important Health ◽  
Shs Exposure ◽  
Very High

Comprehensive smoke-free policies such as those called for by the WHO FCTC are the only way to protect the public effectively from the harms of secondhand smoke (SHS), yet Japan has been slow to implement this important health measure. This study examines baseline levels of smoking and SHS exposure in public places and support for smoking bans in Japan prior to the implementation of the 2018 national smoke-free law. Data are from the International Tobacco Control (ITC) Japan Wave 1 Survey (Feb–Mar 2018), a web survey of adult cigarette smokers, heated tobacco product users, dual users, and non-users (total N = 4684). Measures included prevalence of smoking (whether respondents noticed people smoking inside restaurants and bars at their last visit, and workplaces in the last month), and support for complete smoking bans in these venues. Smoking prevalence in each venue was high overall in 2018 (49% of workplaces, 55% of restaurants, and 83% of bars), even higher than in China, the country with the greatest toll of SHS. Support for complete smoking bans was very high overall (81% for workplaces, 78% for restaurants, and 65% for bars). Non-users were less likely to be exposed to SHS and had higher support for smoking bans than tobacco users. These findings point to the ineffectiveness of partial smoke-free laws in Japan and reinforce the call for comprehensive smoke-free laws, which even smokers would support at higher levels than in many other ITC countries.

Secondhand Smoke Exposure 7 Years After an Indoor Smoke-Free Law

2016 ◽  
Vol 32 (1) ◽  
pp. 131-134 ◽  
Author(s):  
Ann W. St. Claire ◽  
Michael S. Amato ◽  
Raymond G. Boyle ◽  
Peter Rode ◽  
Ann M. Kinney
Keyword(s):  
Secondhand Smoke ◽  
Health Benefit ◽  
Community Settings ◽  
Public Places ◽  
Public Health Benefit ◽  
The Past ◽  
Smoke Free Policy ◽  
Low Incomes ◽  
Random Digit Dial ◽  
Shs Exposure

Purpose: To examine locations of secondhand smoke (SHS) exposure among nonsmokers, 7 years after a statewide smoke-free policy. Design: Data collected via statewide, random digit dial telephone survey. Response rates were 64.7% for landline and 73.5% for cell phone. Setting: Minnesota, 2014. Participants: Representative sample of 7887 nonsmoking adults. Measures: Self-reported locations of SHS exposure and opinions on smoke-free restrictions. Analysis: Descriptive statistics and logistic regression. Results: A total of 35.5% of nonsmokers reported SHS exposure in the past 7 days. The greatest proportion of exposure occurred in community settings (31.7%) followed by cars (6.9%) and in the home (3.2%). Young adults were more likely to be exposed in a home or car than older adults. Nonsmokers living with a smoker were 39.6 (20.6-75.8) times more likely to be exposed to SHS in their home and 5.3 (4.1-6.8) times more likely to be exposed in a car, compared to those who did not live with a smoker. Conclusion: SHS exposure continues after comprehensive smoke-free policies restricted it from public places. Disparities in exposure rates exist for those who live with a smoker, are young, and have low incomes. Findings suggest the need for additional policies that will have the greatest public health benefit.

scholarly journals Exposure to Secondhand Smoke: Inconsistency between Self-Response and Urine Cotinine Biomarker Based on Korean National Data during 2009–2018

2021 ◽  
Vol 18 (17) ◽  
pp. 9284
Author(s):  
Boram Sim ◽  
Myung-Bae Park
Keyword(s):  
Secondhand Smoke ◽  
Vulnerable Groups ◽  
Exposure Rate ◽  
Short Term ◽  
The Past ◽  
Health And Nutrition ◽  
Urine Cotinine ◽  
Short Term Exposure ◽  
Shs Exposure ◽  
Exposure To Secondhand Smoke

This study aimed to estimate the secondhand smoke (SHS) exposure using urinary cotinine (UCo) to prove that the SHS exposure could not be properly assessed by self-reporting (SR). In total, 28,574 nonsmokers aged >19 years were selected from the Korean National Health and Nutrition Examination Survey data (2009–2018). First, changes in the annual concentration of UCo were analyzed, and the annual SHS exposure rates were measured based on SR and UCo from 2009 to 2018. Then, the average UCo concentration and UCo-measured SHS exposure rate were confirmed according to the subjects’ characteristics. Finally, factors associated with the UCo-measured SHS exposure rate were identified based on multiple regression analysis. The findings showed that the annual UCo concentrations and self-reported SHS exposure rates dropped significantly over the past decade. In contrast, the UCo-measured SHS exposure rate indicated that >80% of nonsmokers are still exposed to SHS. Moreover, we found vulnerable groups using UCo-measured SHS exposure rate. In particular, the self-reported SHS exposure at home and in workplaces and house type was highly associated with SHS exposure. Thus, these findings indicate that the actual SHS exposure could not be properly assessed by SR and should be verified using a biomarker, such as UCo. Considering that even a short-term exposure can be harmful to health, the goal of the policy should be to keep cotinine concentration as low as possible.

scholarly journals Estimation of lifetime cumulative mortality risk of lung cancer by smoking status in Japan

2020 ◽  
Vol 50 (10) ◽  
pp. 1218-1224
Author(s):  
Megumi Hori ◽  
Eiko Saito ◽  
Kota Katanoda ◽  
Shoichiro Tsugane
Keyword(s):  
Lung Cancer ◽  
Life Table ◽  
Mortality Risk ◽  
Secondhand Smoke ◽  
Smoking Status ◽  
Cumulative Risk ◽  
Cumulative Mortality ◽  
Shs Exposure ◽  
Estimated Risk ◽  
Exposure To Secondhand Smoke

Abstract The main objective of this study was to estimate the cumulative mortality risk for lung cancer according to smoking status and exposure to secondhand smoke (SHS) in Japan. We applied a life-table method to estimate the cumulative risk. Estimated lifetime cumulative risk for 20-year-old non-smokers, former, and current smokers was 3.2%, 7.6%, and 14.9% for men and 1.9%, 5.6%, and 7.2% for women, respectively. For males, the estimated risk was 3.2% for non-smokers not exposed to SHS and 4.1% for non-smokers exposed to SHS. For females, the estimated risk was 1.9% for non-smokers not exposed to SHS and 2.4% for non-smokers exposed to SHS. Lifetime cumulative mortality risk differed greatly according to smoking status. Moreover, SHS exposure resulted in observable differences in lifetime mortality risk. This study may be useful for the development of tailored prevention programs.

scholarly journals Is exposure to secondhand smoke associated with current depression (PHQ-8) among never-smokers? Results from a survey among German adults

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Fabian Erdsiek ◽  
Patrick Brzoska
Keyword(s):  
Secondhand Smoke ◽  
Logistic Regression Model ◽  
German Health ◽  
Potential Association ◽  
Prevalence Of Depression ◽  
Patient Health ◽  
Shs Exposure ◽  
Interaction Term ◽  
Never Smokers ◽  
Exposure To Secondhand Smoke

Abstract Background Findings on the association between exposure to secondhand smoke (SHS) and depression are contradictory. Comparability of existing research is limited due to varied methods and measures. This study examines the potential association between exposure to SHS and depression and a potential moderation by sex using representative data from Germany. Methods For our study, we used data from the German Health Update (GEDA) 2014/2015 on n = 10,274 never-smokers. We calculated a logistic regression model with an interaction term for potential sex-exposure interactions. We used the self-reported duration of exposure to predict current depression of any type as defined by the Patient Health Questionnaire PHQ-8 (score ≥ 10), accounting for a large number of confounders. Results In our sample, prevalence of depression was 8.8% in women and 5.3% in men. 90.4% were never or almost never exposed to SHS, while 7.1% were exposed < 1 h per day and around 2.5% reported being exposed for ≥1 h per day. While SHS exposure for < 1 h per day was not associated with current depression (OR = 1.54; 95%-CI: 0.93–1.61), SHS exposure for at least 1 h per day was associated with increased odds for current depression (OR = 1.59; 95%-CI: 1.08–2.35). No sex-specific differences were found. Conclusions Higher levels of SHS exposure are associated with current depression, although the nature and direction of the association are still unclear. We identified no differences in the association between men and women. More studies, particularly using longitudinal data, are needed to determine the nature of the association.

scholarly journals Characteristics of Non-Smokers’ Exposure Using Indirect Smoking Indicators and Time Activity Patterns

2020 ◽  
Vol 12 (21) ◽  
pp. 9099
Author(s):  
Byung Lyul Woo ◽  
Min Kyung Lim ◽  
Eun Young Park ◽  
Jinhyeon Park ◽  
Hyeonsu Ryu ◽  
...  
Keyword(s):  
Exposure Time ◽  
Secondhand Smoke ◽  
Activity Patterns ◽  
Time Activity ◽  
Spatial Characteristics ◽  
Exposure Biomarkers ◽  
Shs Exposure ◽  
Temporal And Spatial ◽  
Temporal And Spatial Characteristics ◽  
Exposure To Secondhand Smoke

Since the global enforcement of smoke-free policies, indoor smoking has decreased significantly, and the characteristics of non-smokers’ exposure to secondhand smoke (SHS) has changed. The purpose of this study was to assess the temporal and spatial characteristics of SHS exposure in non-smokers by combining questionnaires and biomarkers with time activity patterns. To assess SHS exposure, biomarkers such as cotinine and 4-(methylnitrosamino)-1-3-(pyridyl)-1-butanol (NNAL) in urine and nicotine in hair were collected from 100 non-smokers in Seoul. Questionnaires about SHS exposure and time activity patterns were also obtained from the participants. The analysis of biomarker samples indicated that about 10% of participants were exposed to SHS when compared with the criteria from previous studies. However, 97% of the participants reported that they were exposed to SHS at least once weekly. The participants were most exposed to SHS in the outdoor microenvironment, where they spent approximately 1.2 h daily. There was a significant correlation between the participants’ time spent outdoors and self-reported SHS exposure time (r2 = 0.935). In this study, a methodology using time activity patterns to assess temporal and spatial characteristics of SHS exposure was suggested. The results of this study may help develop policies for managing SHS exposure, considering the time activity patterns.

Active smoking, secondhand smoke exposure and serum cotinine levels among Cheyenne River Sioux communities in context of a Tribal Public Health Policy

2019 ◽  
pp. tobaccocontrol-2019-055056
Author(s):  
Elena R. O'Donald ◽  
Curtis P. Miller ◽  
Rae O'Leary ◽  
Jennifer Ong ◽  
Bernadette Pacheco ◽  
...  
Keyword(s):  
American Indians ◽  
Secondhand Smoke ◽  
Smoking Status ◽  
Statistical Modelling ◽  
Tobacco Consumption ◽  
Health Study ◽  
Serum Cotinine ◽  
Free Air ◽  
Shs Exposure ◽  
Cheyenne River

IntroductionAmerican Indians and Alaska Natives face disproportionately high rates of smoking and secondhand smoke (SHS) exposure. The Cheyenne River Sioux Tribe (CRST) is among the few Tribal Nations controlling commercial tobacco exposures in public and work places. We had an opportunity to explore effects of the new commercial tobacco-free policy (implemented in 2015) in an environmental health study (2014–2016) that collected information about commercial tobacco use and SHS prevalence and examined predictor variables of serum cotinine concentrations.MethodsSelf-reported survey data were used in quantile regression statistical modelling to explore changes in cotinine levels, based on smoking status, smokeless tobacco consumption and SHS exposure.ResultsFrom enrolled 225 adults, 51% (N=114) were current smokers. Among 88 non-tobacco users, 35 (40%) reported current SHS exposure. Significant differences in cotinine median concentrations were found among participants with and without current SHS exposure. Extremely high cotinine concentrations (~100 times larger than the median) were detected in some non-tobacco users. After implementing the new smoke-free air Tribal policy, cotinine decreased in participants with intermediate (3–15 ng/mL, non-tobacco users with SHS exposure) and high (>15 ng/mL, mainly tobacco users) cotinine levels showing association with an abatement of opportunities for SHS exposure. Significant predictors of cotinine levels were sampling year, current smoking and tobacco chewing. No gender differences were observed in cotinine.ConclusionsOur results show decrease in cotinine concentrations in CRST participants since implementation of their ‘Smoke-Free Clean Air Act’ in 2015.

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