scholarly journals Monitoring Interval Cancers in Breast Screening Programmes: The East Anglian Experience

1995 ◽  
Vol 2 (4) ◽  
pp. 180-185 ◽  
Author(s):  
Nicholas Day ◽  
Jenny McCann ◽  
Corinne Camilleri-Ferrante ◽  
Peter Britton ◽  
Graham Hurst ◽  
...  
Keyword(s):  
United Kingdom ◽  
Breast Cancer Mortality ◽  
Interval Cancer ◽  
Contributory Factor ◽  
Interval Cancers ◽  
East Anglia ◽  
The United Kingdom ◽  
Cancer Rates ◽  
Screening Mammograms ◽  
Using Data

Interval cancer rates are a major determinant of the success of a screening programme. In the Swedish two county study, on which the United Kingdom programme is based, a 39% reduction in mortality was observed in screened women aged 50–64. Using data from the Swedish study, the relationship between interval cancer incidence and the likely future effect on breast cancer mortality was quantified. In East Anglia, as elsewhere in the United Kingdom, interval cancers rates are nearly double those obtained in Sweden: interval cancer rates in the first, second, and third years respectively, after a negative screen were 24%, 59%, and 79% of the expected underlying incidence in the absence of screening. The corresponding figures from the two county study were 17%, 30%, and 56%. From these it was estimated that the mortality reduction in East Anglia will be 21%, which is lower than the 35% observed in invited women in this age group in the Swedish two county study and the 25% specified in the Health of the Nation target. In a rereading exercise, using screening mammograms from women who were screen normal, who had screen detected cancers, or who subsequently developed interval cancers, four out of five radiologists recommended recall for around 70% of the original mammograms (classed as screen normal at time of screening) from 33 interval cancers. This suggests that sensitivity is a contributory factor to the higher interval cancer rates in East Anglia.

scholarly journals Breast Density and Risk of Interval Cancers: The Effect of Annual Versus Biennial Screening Mammography Policies in Canada

2021 ◽  
pp. 084653712110279
Author(s):  
Jean Morag Seely ◽  
Susan Elizabeth Peddle ◽  
Huiming Yang ◽  
Anna M. Chiarelli ◽  
Megan McCallum ◽  
...  
Keyword(s):  
Screening Program ◽  
Breast Cancer Mortality ◽  
Interval Cancer ◽  
Screening Mammography ◽  
Dense Breast ◽  
Breast Cancers ◽  
Interval Cancers ◽  
Screening Programs ◽  
Dense Breasts ◽  
Cancer Rates

Regular screening mammography reduces breast cancer mortality. However, in women with dense breasts, the performance of screening mammography is reduced, which is reflected in higher interval cancer rates (ICR). In Canada, population-based screening mammography programs generally screen women biennially; however, some provinces and territories offer annual mammography for women with dense breast tissue routinely and/or on recommendation of the radiologist. This study compared the ICRs in those breast screening programs with a policy of annual vs. those with biennial screening for women with dense breasts. Among 148,575 women with dense breasts screened between 2008 to 2010, there were 288 invasive interval breast cancers; screening programs with policies offering annual screening for women with dense breasts had fewer interval cancers 63/70,814 (ICR 0.89/1000, 95% CI: 0.67-1.11) compared with those with policies of usual biennial screening 225/77,761 (ICR 1.45 /1000 (annualized), 95% CI: 1.19-1.72) i.e. 63% higher (p = 0.0016). In screening programs where radiologists’ screening recommendations were able to be analyzed, a total of 76,103 women were screened, with 87 interval cancers; the ICR was lower for recommended annual (65/69,650, ICR 0.93/1000, 95% CI: 0.71, 1.16) versus recommended biennial screening (22/6,453, ICR 1.70/1000 (annualized), 95%CI: 0.70, 2.71)(p = 0.0605). Screening program policies of annual as compared with biennial screening in women with dense breasts had the greatest impact on reducing interval cancer rates. We review our results in the context of current dense breast notification in Canada.

Interval Breast Cancers in the NHS Breast Screening Programme: Does the Current Definition Exclude Too Many?

1997 ◽  
Vol 4 (3) ◽  
pp. 169-173 ◽  
Author(s):  
A M Faux ◽  
D C Richardson ◽  
G M Lawrence ◽  
M E Wheaton ◽  
M G Wallisconsultant
Keyword(s):  
Breast Screening ◽  
Interval Cancer ◽  
Breast Cancers ◽  
Interval Cancers ◽  
Exclusion Criteria ◽  
National Statistics ◽  
Screening Unit ◽  
Cancer Rates ◽  
Definition Of ◽  
The Impact

Objectives— To examine the impact of the definition of interval breast cancers on interval cancer rates arising from the prevalent (first) screening round. Design— Interval breast cancers arising from the prevalent (first) screening round at the Warwickshire, Solihull and Coventry Breast Screening Unit (17 April 1989 to 31 March 1992) were identified by comparison of data held at the unit with records at the West Midlands Cancer Intelligence Unit. Exclusion criteria used in National statistics were applied to this sample to quantify their impact on achieved interval cancer rates. The round lengths experienced by individual women at the unit were determined from the prevalent and incident invitation dates for 155 women with incident (re-screen) breast cancers detected in the second round. Setting— Warwickshire, Solihull and Coventry Breast Screening Unit. Subects—59 017 women screened between 17 April 1989 and 31 March 1992 with a negative screening result and 155 women with incident screen detected cancers. Results— A total of 278 interval cancers were identified, giving an overall rate from the prevalent screening round of 47.1/10 000 women screened. Of these, 213 met the criteria used in the definition of interval cancers for National statistics and were termed “core” interval cancers. The overall “core” interval rate was 36.1/10 000 women screened, similar to interval cancer rates found in the north west of United Kingdom. Thus applying commonly used exclusion criteria produced a 23.4% reduction in the apparent interval cancer rate, with the largest decrease resulting from the exclusion of cancers arising at 36 months or more from the last screen. Conclusions— The exclusion criteria used in the definition of interval cancers have a significant impact on observed interval cancer rates. Of particular concern is the exclusion in the current National definitions of cancers arising at 36 months or more from the last screen, which may mask a problem with significant implications for the success of the NHSBSP.

Migration Processes among the Highly Skilled in Europe

1992 ◽  
Vol 26 (2) ◽  
pp. 484-505 ◽  
Author(s):  
John Salt
Keyword(s):  
United Kingdom ◽  
Skilled Workers ◽  
Migration Process ◽  
The United Kingdom ◽  
Highly Skilled ◽  
European Business ◽  
Business Structures ◽  
Using Data ◽  
Corporate Business ◽  
Official Sources

This article seeks to show that the migration process for highly skilled workers in contemporary Europe is part of the structuring of European business. It focuses on the employer's perspective and role in articulating movement, using data from various official sources as well as survey evidence from the United Kingdom. It suggests that the increasing importance of this form of mobility is related to the process of internationalization by large employers and that the particular form of movement is dependent on the evolution of corporate business structures.

scholarly journals I.—Trogontherium from a Pleistocene Deposit in the Thames Valley

1902 ◽  
Vol 9 (9) ◽  
pp. 385-388 ◽  
Author(s):  
E. T. Newton
Keyword(s):  
United Kingdom ◽  
Geological Survey ◽  
Incisor Tooth ◽  
Glacial Deposits ◽  
East Anglia ◽  
Charles Lyell ◽  
The United Kingdom ◽  
Sandy Deposit ◽  
History Of ◽  
Pleistocene Deposit

The history of this gigantic rodent began to be written in 1809, when M. Gothelf Fischer described a skull from a sandy deposit on the borders of the Sea of Azof, to which he gave the name of Trogontherium. Since then, at varying intervals, to the present time, new chapters have been added to this history by both Continental and British workers, describing specimens of a more or less fragmentary character which have from time to time been discovered. The English specimens have been chiefly obtained from the ‘Cromer Forest Bed,’ that rich and remarkable series of beds occupying a position in time between the Crags and the Glacial deposits of East Anglia. The ‘Forest Bed’ specimens were first made known by Sir Charles Lyell in 1840, but were more fully described by Sir R. Owen in 1846 and referred to Fischer's Trogontherium Cuvieri. It will not be necessary at this time to refer specifically to each of the additions to our knowledge of this animal or to detail the varying opinions as to affinities and nomenclature, as these particulars will be found in the Memoirs of the Geological Survey of the United Kingdom. Although most of the British specimens of Trogontherium Cuvieri have been found in the ‘Cromer Forest Bed’ a few examples have been met with in the Norwich and Weybourn Crags. The smaller species, which has been called T. minus, was obtained from the nodule bed below the Red Crag of Felixstowe, and an incisor tooth from the Norwich Crag was referred to the same species.

scholarly journals Gypsy–Traveller communities in the United Kingdom and the Netherlands: socially and digitally excluded?

2018 ◽  
Vol 42 (5) ◽  
pp. 637-653
Author(s):  
Leanne Townsend ◽  
Koen Salemink ◽  
Claire Denise Wallace
Keyword(s):  
United Kingdom ◽  
The Netherlands ◽  
Digital Communications ◽  
Digital Inclusion ◽  
Left Behind ◽  
The United Kingdom ◽  
Mainstream Society ◽  
Using Data ◽  
Socially Excluded ◽  
The Impact

With the pervasiveness of digitisation communications, those that are left behind are seen as socially excluded. In both academic and policy discourses, it is assumed that digital inclusion as a route into mainstream society is a desirable solution to problems of multiple exclusion and has led to many studies of the digital inclusion/exclusion of ‘hard to reach’ groups. Yet, Gypsy–Travellers, among the most marginalised people in society, have received little attention. Using data from the Netherlands and the United Kingdom, we assess the impact of digital communications on Gypsy–Traveller communities. This article makes a contribution in the following ways: First, we address the theories of ‘fields of inclusion’ to show how exclusion and inclusion work together in different ways; Second, we explore how different policy frameworks in the Netherlands and the United Kingdom shape these possibilities; Third, we document the forms of inclusion that Gypsy–Travellers experience in terms of digital communications; Fourth, we look at how Gypsy–Travellers use digital communications to recreate their own cultures as well as selectively integrate with mainstream society.

Takeover, Closures, and the Restructuring of the United Kingdom Ironfoundry Industry

1983 ◽  
Vol 15 (5) ◽  
pp. 639-661 ◽  
Author(s):  
I J Smith ◽  
M J Taylor
Keyword(s):  
United Kingdom ◽  
Postwar Period ◽  
Plant Closure ◽  
The United Kingdom ◽  
Using Data ◽  
The Impact ◽  
Peripheral Regions

This paper explores the regional dimension of plant and firm closure in the United Kingdom using data for the ironfoundry industry over the whole of the postwar period but with particular emphasis on the 1967–1980 period. The impact of ownership on plant closure is stressed, and patterns of ownership change are shown to seriously prejudice the survival of plant in the industry in UK peripheral regions.

scholarly journals Disease threat does not predict attractiveness preference in a United Kingdom dataset: a replication attempt and commentary on White et al., Psych Sci 2013

2015 ◽  
Author(s):  
Gustav Nilsonne ◽  
Adam Renberg ◽  
Sandra Tamm ◽  
Mats Lekander
Keyword(s):  
United Kingdom ◽  
Cultural Differences ◽  
Disease Burden ◽  
Congressional Elections ◽  
Cross Cultural ◽  
Self Rated Health ◽  
Cross Cultural Differences ◽  
Members Of Parliament ◽  
The United Kingdom ◽  
Using Data

Background: A study by White et al. found that population disease burden predicted preference for attractive politicians in U.S. congressional elections. Aim: We aimed to replicate this finding using data from the United Kingdom. Method: We regressed rated sexiness of elected members of parliament on health metrics from their constituencies: life expectancy, infant mortality, and self-rated health. Results: None of the health metrics predicted rated sexiness of members of parliament. Conclusion: Further investigation is needed to verify whether the proposed relationship is important and whether it is moderated by other factors such as cross-cultural differences.

What Explains The Existence of an Exchange Overround?

2013 ◽  
pp. 275-297
Author(s):  
David Marginson
Keyword(s):  
United Kingdom ◽  
Market Efficiency ◽  
Positive Relationship ◽  
Microstructure Analysis ◽  
Horse Race ◽  
The United Kingdom ◽  
Betting Markets ◽  
Using Data ◽  
Starting Price

This chapter analyzes factors that may explain the existence and magnitude of starting price–based overrounds on Betfair, the leading and globally dominant person-to-person Internet betting site. Drawing on both finance and horse race betting literatures, several hypotheses are developed and tested, using data on 2,184 horse races in the United Kingdom between 2008 and 2010. Results are discussed and explanations offered for the findings, such as a positive relationship between grade of race and Betfair overround (the higher the grade, the higher the overround). More broadly, this research suggests that microstructure analysis of order-driven betting markets, such as Betfair, constitutes a fruitful line of enquiry for those interested in understanding market efficiency.

Sign in / Sign up

Export Citation Format

Share Document