Prevalence, detection and associations of depression in Australian dialysis patients

Objective:Depression in dialysis patients is often undetected despite associations with poor outcomes. The aim was to determine the prevalence and associations of depressive symptoms and physician recognition of depression within a typical Australian dialysis population.Method:A cross-sectional study examined haemodialysis and peritoneal dialysis patients of two hospitals in Sydney. Participants were screened for depression using the Hospital Anxiety and Depression Scale (HADS).Results:One hundred and ten patients completed the HADS. Subjects had a mean age of 63.7 years, 37% from a culturally and linguistically diverse background, and median dialysis duration of 2 years. Forty-one per cent of participants had significant depressive symptoms, of whom 42% had been diagnosed with depression by their clinicians. After adjustment for sociodemographic factors, having >10 medications prescribed, >3 hospitalisations in the last 12 months, and a history of depression were associated with depression.Conclusion:Depressive symptoms are prevalent in Australian dialysis patients. Robust evidence is needed on the effectiveness of treatments for depression in changing outcomes in chronic kidney disease.

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Weight Status and Depressive Smptoms in 18 Year-Old Greek Adolescents

Pediatric Reports ◽

10.4081/pr.2010.e16 ◽

2010 ◽

Vol 2 (2) ◽

pp. 51-54

Author(s):

Vasiliki Matziou ◽

Kalliopi Hatira ◽

Pantelis Perdikaris ◽

Ioannis Zachos ◽

Kassiani Mellou ◽

...

Keyword(s):

Depressive Symptoms ◽

Weight Status ◽

Univariate Analysis ◽

Depression Scale ◽

Cross Sectional Study ◽

Epidemiologic Studies ◽

Cross Sectional ◽

History Of ◽

Mental Institution ◽

Old Greek

Depressive symptoms in adolescence have been a subject of considerable controversy in terms of their nature, severity and identification. The aim of the study was to investigate the possible association between weight status and depressive symptoms among 18 year-old Greek adolescents. A cross-sectional study design was used. The study population consisted of 200 students of the University of Athens who fulfilled the following criteria: age 18 years, absence of clinical depression, no history of hospitalization in a mental institution, no history of alcohol abuse. Weight status was assessed by Body Mass Index (BMI) (kg/m2) and calculated from weight and height measurements. Severity of depressive symptoms was assessed by Centre for Epidemiologic Studies-Depression Scale (CES-D). In univariate analysis, CES-D score was significantly associated with adolescents’ gender and BMI. The multivariate analysis showed that CES-D score was negatively related to BMI even after controlling the confounding effect of gender (P=0.018, B=-0.378). Depressive symptoms are related to weight status of adolescents.

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Depressive symptoms in urban population samples in Russia, Poland and the Czech Republic

The British Journal of Psychiatry ◽

10.1192/bjp.188.4.359 ◽

2006 ◽

Vol 188 (4) ◽

pp. 359-365 ◽

Cited By ~ 56

Author(s):

Martin Bobak ◽

Hynek Pikhart ◽

Andrzej Pajak ◽

Ruzena Kubinova ◽

Sofia Malyutina ◽

...

Keyword(s):

Czech Republic ◽

Depressive Symptoms ◽

Soviet Union ◽

Urban Population ◽

Depression Scale ◽

Epidemiological Studies ◽

Sociodemographic Factors ◽

Cross Sectional Study ◽

Cross Sectional ◽

The Czech Republic

BackgroundRelatively little is known about depression in countries that were formerly part of the Soviet Union, especially Russia.AimsTo investigate the rates and distribution of depressive symptoms in urban population samples in Russia, Poland and the Czech Republic.MethodA cross-sectional study was conducted in randomly selected men and women aged 45–64 years (n=2151 intotal, response rate 69%) in Novosibirsk (Russia), Krakow (Poland) and Karvina (Czech Republic). The point prevalence of depressive symptoms in the past week was defined as a score of at least 16 on the Center for Epidemiological Studies Depression scale.ResultsIn men the prevalence of depressive symptoms was 23% in Russia, 21% in Poland and 19% in the Czech Republic; in women the rates were 44%, 40% and 34% respectively. Depressive symptoms were positively associated with material deprivation, being unmarried and binge drinking. The association between education and depression was inverse in Poland and the Czech Republic but positive in Russia.ConclusionsThe prevalence of depressive symptoms in these eastern European urban populations was relatively high; as in other countries, it was associated with alcohol and several sociodemographic factors.

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Self-Reported Depressive Symptoms in Association with Medication Exposures among Medical Inpatients: A Cross-Sectional Study

The Canadian Journal of Psychiatry ◽

10.1177/070674379504000508 ◽

1995 ◽

Vol 40 (5) ◽

pp. 264-269 ◽

Cited By ~ 7

Author(s):

B. Patten Scott ◽

V.A. Williams Jeanne ◽

J. Love Edgar

Keyword(s):

Depressive Symptoms ◽

Enzyme Inhibitors ◽

Angiotensin Converting Enzyme Inhibitors ◽

Cross Sectional Study ◽

Channel Blockers ◽

Converting Enzyme Inhibitors ◽

Cross Sectional ◽

Medical Inpatients ◽

History Of ◽

History Of Depression

Objective To evaluate associations between exposure to three classes of medications (angiotensin converting enzyme inhibitors, calcium channel blockers, and corticosteroids) and self-reported depressive symptoms. Method The study utilised a cross-sectional study design in a sample of medical inpatients. Results Associations between self-reported depressive symptoms and exposure to angiotensin converting enzyme inhibitors or calcium channel blockers were not observed. However, an association between self-reported depressive symptoms and corticosteroid exposure was identified. The association was strongest in subjects reporting apast history of depression or a family history of depression. The strength of the corticosteroid-depressive symptom association was comparable with that of associations observed for age, poverty and psychosocial stress. Conclusions Depressive symptoms among medical inpatients have a biopsychosocial etiology. Corticosteroid exposure may be a biological risk factor for depressive symptoms in this population.

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Watching sports and depressive symptoms among older adults: a cross-sectional study from the JAGES 2019 survey

Scientific Reports ◽

10.1038/s41598-021-89994-8 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Taishi Tsuji ◽

Satoru Kanamori ◽

Ryota Watanabe ◽

Meiko Yokoyama ◽

Yasuhiro Miyaguni ◽

...

Keyword(s):

Older Adults ◽

Depressive Symptoms ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Mail Survey ◽

Prevalence Ratio ◽

Average Frequency ◽

Evaluation Study ◽

Cross Sectional Study ◽

Cross Sectional

AbstractThe current study investigated the relationship between the frequency of watching sports and depressive symptoms among older adults. This study used cross-sectional data from the Japan Gerontological Evaluation Study, a nationwide mail survey of 21,317 older adults. Depressive symptoms were defined as a Geriatric Depression Scale score of ≥ 5. Participants were queried regarding the average frequency at which they watched sports on-site and via TV/Internet over the past year. Among the 21,317 participants, 4559 (21.4%) had depressive symptoms, while 4808 (22.6%) and 16,576 (77.8%) watched sports on-site and via TV/Internet at least once a year, respectively. Older adults who watched sports on-site a few times/year (prevalence ratio, 0.70; 95% confidence interval, 0.65–0.74) or 1–3 times/month (0.66, 0.53–0.82) were less likely to have depressive symptoms compared to non-spectators after adjusting for frequency of playing sports, exercise activities, and other potential confounders. Meanwhile, a dose–response relationship was confirmed for watching via TV/Internet (prevalence ratio of 0.86, 0.79, and 0.71 for a few times/year, 1–3 times/month, and ≥ 1 time/week, respectively). This study suggested that watching sports on-site or via TV/Internet, regardless of whether they regularly engage in sports, may reduce the risk of depressive symptoms among older adults.

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Assessing the Impact of a Hilly Environment on Depressive Symptoms among Community-Dwelling Older Adults in Japan: A Cross-Sectional Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18094520 ◽

2021 ◽

Vol 18 (9) ◽

pp. 4520

Author(s):

Takafumi Abe ◽

Kenta Okuyama ◽

Tsuyoshi Hamano ◽

Miwako Takeda ◽

Masayuki Yamasaki ◽

...

Keyword(s):

Older Adults ◽

Depressive Symptoms ◽

Depression Scale ◽

Cross Sectional Study ◽

Community Dwelling ◽

Rural Setting ◽

Sectional Study ◽

Cross Sectional ◽

The Impact ◽

Community Dwelling Older Adults

Although some neighborhood environmental factors have been found to affect depressive symptoms, few studies have focused on the impact of living in a hilly environment, i.e., land slope, on depressive symptoms among rural older adults. This cross-sectional study aimed to investigate whether a land slope is associated with depressive symptoms among older adults living in rural areas. Data were collected from 935 participants, aged 65 years and older, who lived in Shimane prefecture, Japan. Depressive symptoms were assessed using the Zung Self-Rating Depression Scale (SDS) and defined on the basis of an SDS score ≥ 40. Land slopes within a 400 m network buffer were assessed using geographic information systems. Odds ratios (ORs) with 95% confidence intervals (CIs) of depressive symptoms were estimated using logistic regression. A total of 215 (23.0%) participants reported depressive symptoms. The land slope was positively associated with depressive symptoms (OR = 1.04; 95% CI = 1.01–1.08) after adjusting for all confounders. In a rural setting, living in a hillier environment was associated with depressive symptoms among community-dwelling older adults in Japan.

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Association between glaucomatous optic disc and depressive symptoms independent of light exposure profiles: a cross-sectional study of the HEIJO-KYO cohort

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2018-312176 ◽

2018 ◽

Vol 103 (8) ◽

pp. 1119-1122 ◽

Cited By ~ 2

Author(s):

Tadanobu Yoshikawa ◽

Kenji Obayashi ◽

Kimie Miyata ◽

Tetsuo Ueda ◽

Norio Kurumatani ◽

...

Keyword(s):

Depressive Symptoms ◽

Optic Disc ◽

Light Exposure ◽

Depression Scale ◽

Cross Sectional Study ◽

Confounding Factors ◽

Sectional Study ◽

Night Time ◽

Cross Sectional ◽

Optic Discs

BackgroundGlaucoma may cause physiological and behavioural circadian misalignment because of the loss of intrinsically photosensitive retinal ganglion cells, the primary receptors of environmental light. Although studies have suggested a high prevalence of depression in patients with glaucoma, it is unclear whether the association is independent of the light exposure profiles as an important confounding factor.MethodsIn this cross-sectional study of a community-based cohort of 770 elderly individuals (mean age, 70.9 years), glaucomatous optic discs were assessed using fundus photographs and depressive symptoms were assessed using the short version of the Geriatric Depression Scale (GDS). Daytime and night-time ambient light exposures were objectively measured for 2 days.ResultsDepressive symptoms (GDS score ≥6) were observed in 114 participants (prevalence, 14.8%) and glaucomatous optic discs were detected in 40 participants (prevalence, 5.2%). The prevalence of depressive symptoms was significantly higher in the group with glaucomatous optic disc than in the group without it (30.0% vs 14.0%, respectively; p=0.005). Multivariable logistic regression analysis adjusted for potential confounding factors, including daytime and night-time light exposures, revealed that the OR for depressive symptoms was significantly higher in the group with glaucomatous optic disc than in the group without it (OR 2.45, 95% CI 1.18 to 5.08; p=0.016).ConclusionsIn this general elderly population, glaucomatous optic disc was significantly associated with higher prevalence of depressive symptoms independent of a number of potential confounding factors, including daily light exposure profiles.

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Cognition, Depressive Symptoms and Vascular Factors among Southwest Tribal Elders

Ethnicity & Disease ◽

10.18865/ed.26.2.235 ◽

2016 ◽

Vol 26 (2) ◽

pp. 235 ◽

Cited By ~ 1

Author(s):

Francine Gachupin ◽

Michael D. Romero ◽

Willa J. Ortega ◽

Rita Jojola-Dorame ◽

Hugh Hendrie ◽

...

Keyword(s):

Depressive Symptoms ◽

Geriatric Depression Scale ◽

Memory Loss ◽

Depression Scale ◽

Vascular Risk ◽

Tribal Community ◽

Cross Sectional ◽

Pilot Studies ◽

Physical Measurements ◽

History Of

Objectives: Few data exist on cognitive and depressive symptoms and vascular factors in American Indian (AI) elders. Since vascular risk factors increase risk for cognitive impairments, depression and dementia, and since AI elders are at high vascular risk, it is timely to assess the interplay of these factors in comprehensive studies of aging in this population. To begin, pilot studies must be conducted to show these types of data can be collected successfully.Design: A cross-sectional pilot study, the Southwest Heart Mind Study (SHMS). Setting: Tribal community in the Southwest United States. Participants: AI elders, aged ≥55 years.Main Outcome Measures: Cross-cultural demographic, social network and risk factor surveys; tests of cognition, depression and anxiety; physical measurements; blood biochemistries; and APOE genotyping.Results: SHMS elders were comparable to other rural elder populations on cognitive and depressive symptom scores. The average CogScore was 28.8 (out of 32), the average Geriatric Depression Scale (GDS) was 6.7 (of 30), and the average Hamilton Anxiety Scale was 1.2 (of 4). 32% possessed at least one APOEe4 allele. High vascular risk was evident: 76% were overweight or obese; 54% self-reported history of hypertension; 24% heart trouble; 32% type 2 diabetes; 35% depression; and 24% a family history of serious memory loss. More than 70% reported prescription medication use. 54% cared for someone besides self.Conclusions: A better understanding of the burden of vascular risk in relation to cognition and depression among Southwest Tribes is needed. Ethn Dis. 2016;26(2):235- 244; doi:10.18865/ed.26.2.235

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Evaluating depression and suicidality in tetrabenazine users with Huntington disease

Neurology ◽

10.1212/wnl.0000000000005817 ◽

2018 ◽

Vol 91 (3) ◽

pp. e202-e207 ◽

Cited By ~ 9

Author(s):

Jordan L. Schultz ◽

Annie Killoran ◽

Peg C. Nopoulos ◽

Chloe C. Chabal ◽

David J. Moser ◽

...

Keyword(s):

Suicidal Ideation ◽

Huntington Disease ◽

Cross Sectional Study ◽

Cag Repeat ◽

Cross Sectional ◽

Increased Risk ◽

History Of ◽

Antidepressant Use ◽

History Of Depression ◽

Total Functional Capacity

ObjectiveTo determine whether tetrabenazine (TBZ) use is associated with an increased incidence of depression and/or suicidal ideation.MethodsIn this retrospective cross-sectional study of the Enroll-HD database, we used multiple logistic regression analyses to determine whether TBZ use is associated with an increased incidence of depression and/or suicidal ideation. For both dependent variables (depression and suicidality), separate analyses were conducted on (1) all participants, (2) only participants with a history of depression, and (3) only participants with no history of depression. Adjustments were made for CAG repeat length, total motor score, total functional capacity, Symbol Digit Modalities Test score, sex, disease duration, history of depression (when applicable), antipsychotic use, and antidepressant use.ResultsCompared to participants who were not using TBZ (n = 3,548), TBZ users (n = 543) did not have an increased risk of depression (odds ratio [OR] = 0.78, p = 0.064). Participants taking TBZ actually had a relatively lower risk of suicidality (OR = 0.61, p = 0.043). Among only participants with a history of depression, those using TBZ had a lower incidence of depression (OR = 0.71, p = 0.016) and suicidal ideation (OR = 0.57, p = 0.028) compared to those not using TBZ. Finally, among only participants with no history of depression, TBZ use was not associated with a higher incidence of depression (OR = 1.59, p = 0.18) or suicidality (OR = 1.43, p = 0.66) compared to those who were not using TBZ.ConclusionsTBZ use was not associated with an increased incidence of depression or suicidality. These findings suggest that TBZ may be safe to use in patients with Huntington disease who have a history of depression.

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Depressive Symptoms in Dialysis: Prevalence and Relationship with Uremia-Related Biochemical Parameters

Blood Purification ◽

10.1159/000491014 ◽

2018 ◽

Vol 46 (4) ◽

pp. 286-291 ◽

Cited By ~ 5

Author(s):

Luigi Cirillo ◽

Roberta Cutruzzulà ◽

Chiara Somma ◽

Marco Gregori ◽

Giuseppe Cestone ◽

...

Keyword(s):

Depressive Symptoms ◽

Functional Impairment ◽

Biochemical Parameter ◽

Serum Levels ◽

Cross Sectional Study ◽

Dialysis Patients ◽

Cross Sectional ◽

Patient Health ◽

Laboratory Variables ◽

The Impact

Background: Depression is the most common psychiatric disorder in long-term dialysis patients and a risk factor for morbidity and mortality. Although there is a relevance of the issue in the dialysis setting, we still know little about possible relationships between depression and uraemia-related biochemical abnormalities. Our aims were to evaluate (1) the prevalence of depression in our haemodialysis (HD) and peritoneal dialysis (PD) population using a validated and easy-to-implement screening tool and (2) the association between depression and the main uraemia-related clinical and biochemical parameter changes. Methods: In this monocentric cross-sectional study, all patients of our centre with at least 3 months of dialysis were screened by Patient Health Questionnaire-9 (PHQ-9), a self-administered depression-screening questionnaire validated in dialysis setting. The impact of depressive symptoms on daily life was also assessed. We then analysed relationships between the PHQ-9-derived depressive score, functional impairment score, demographic, clinical and laboratory variables. Results: In our cohort of 145 patients, depressive symptoms were found in 69 patients (46%). Stratifying for severity, mild, moderate and severe grade accounted for 31, 13 and 2% respectively. Depressive symptoms affected 36% of patients on PD versus 52% of patients on HD. Moreover, the PD patients had significantly less functional impairment derived from depressive symptoms than the HD patients. Simple and multiple regression analysis identified serum phosphorus as the only uraemia-related laboratory parameter that was high statistically associated with depressive score. Conclusions: Using a reliable, simple and fast tool, we found that depressive symptoms affect almost half of dialysis patients, particularly so the HD cohort. Severity of depressive symptoms seems related to serum levels of phosphorus possibly because depression affects compliance to therapy.

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Abstract P543: Association Of Tanning Bed Use With Depression In A Preventive Medicine Cohort: The Cooper Center Longitudinal Study

Circulation ◽

10.1161/circ.141.suppl_1.p543 ◽

2020 ◽

Vol 141 (Suppl_1) ◽

Author(s):

Katie Kinser ◽

Beth B Wright ◽

David Leonard ◽

Laura F Defina

Keyword(s):

Depressive Symptoms ◽

Preventive Medicine ◽

Personal History ◽

Healthy Population ◽

Cross Sectional ◽

Tanning Beds ◽

Increased Risk ◽

Tanning Bed ◽

History Of ◽

History Of Depression

Importance: The use of tanning beds continues despite evidence of increased skin cancer risk among users. In the US, the prevalence of indoor tanning ranges from 35% of adults to 59% of college students. Objective: To investigate the association between depressive symptoms and tanning bed use. Design: Cross-sectional study. Setting: A preventive medicine clinic in Dallas, Texas. Participants: Between September 2013 and June 2019, a total of 11,823 generally healthy men and women presented for preventive medical examinations. Exposure: Self-reported tanning bed use. Main Outcome and Measures: Depressive symptoms as indicated by a score of greater than or equal to 10 on the Center for Epidemiologic Studies Depression (CES-D) Scale. Results: Fifteen percent of participants had used a tanning bed prior to their examination. For men, tanning bed use was associated with an increased risk of depressive symptoms (OR: 1.86; 95% CI:1.41-2.44). For women, the association between the use of tanning beds and depressive symptoms was significant in an unadjusted model, but was no longer significant after adjustment for confounders (OR: 1.26; 95% CI:0.99-1.61). However, the odds ratio was still in the direction of increased risk. Women with a personal history of depression were more likely to tan frequently and have higher CES-D scores than women with no personal history of depression ( p = .003). Conclusions and Relevance: In a generally healthy population, depressive symptoms were associated with the use of a tanning bed. This association was more evident in those with a history of depression, although remained true for those without a history of depression. As recurrent tanning bed use is known to contribute to the diagnosis of melanoma, it is critical to help patients identify other options to treat depression as well as to educate them on the risks of routine tanning bed use.

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