A Histopathologic Approach to Uterine Niche: What to Expect and to Report in Hysteroscopy-Resected Isthmocele Specimens

2021 ◽  
pp. 106689692110394
Author(s):  
Badr AbdullGaffar ◽  
Amal Almulla
Keyword(s):  
Surgical Repair ◽  
Fertility Restoration ◽  
Previous History ◽  
Clinical Findings ◽  
Foreign Body Giant Cell ◽  
Cell Reaction ◽  
Stromal Tissue ◽  
History Of ◽  
Review Study ◽  
Histopathologic Features

As one of the emerging complications of caesarean sections (CSs), pathologists will have an important role in handling samples of uterine niches. An isthmocele is a defect at the site of a previous CS scar resulting in a variety of symptoms and niche-related subfertility. There is a deficiency in the literature of the histopathologic features of hysteroscopy-resected isthmocele ridges. Our aim is to fill this gap to highlight what to expect to see and what important findings to report to guide gynecologists to the results of hysteroscopic isthmoplasty in relation to symptoms improvement, fertility restoration, and potential complications. We found 22 cases of hysteroscopy-resected isthmoceles by performing a retrospective review study. The majority of the women were symptomatic with secondary infertility. The resected isthmocele edges were lined by endocervical, endometrial, and isthmic mucosa either combined or isolated depending on each case. Isthmoceles could be classified depending on the predominant lining mucosa into endocervical-isthmoendocervical (low) and endometrial-isthmic (high-intermediate) niches. This could be correlated with certain symptoms. The edges showed variably thickened fibrous and fibromuscular stromal tissue with characteristic thick-walled blood vessels. Some cases showed miscellaneous findings such as hemosiderin pigments with foreign body giant cell reaction and placental implantation site tissue reflecting a previous history of surgical repair and scar pregnancy. Cauterization artifacts may impose interpretation challenges for pathologists. Utility of certain special stains helps delineate the nature of badly cauterized tissues. It is important to report certain histologic findings in isthmocele samples to correlate with clinical findings and guide gynecologists.

Syphilis among men who have sex with men attending a large HIV clinic in Trinidad

2021 ◽  
pp. 095646242199719
Author(s):  
Robert Jeffrey Edwards ◽  
Isshad John ◽  
Selena Todd ◽  
Leon-Omari Lavia ◽  
David Musa ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Chart Review ◽  
Laboratory Data ◽  
Previous History ◽  
History Of ◽  
Review Study ◽  
Sex With Men ◽  
Associated Risk Factors ◽  
Living With Hiv ◽  
Age Range

A chart review study was conducted to determine the prevalence of syphilis and explore the associated risk factors among men who have sex with men (MSM) who attended a large HIV clinic in Trinidad during the period January–December 2019. Patients were routinely screened for syphilis annually, and demographic, clinical, and laboratory data were extracted from the medical records. Descriptive and bivariate analyses were performed, and factors significantly associated with a syphilis diagnosis were assessed using multivariate logistic regression. During the period, 218 MSM were seen, age range 19–67 years, and median age 34.0 years. The prevalence of syphilis was 41.3% (90/218), and 71.1% (64//90) of these infections were asymptomatic. Multivariate analysis using logistic regression showed that MSM living with HIV in the 30–34 years old-age group (OR, 4.32; 95% CI, 1.04–18.02), and those with a previous history of treated syphilis (OR, 10.18; 95% CI, 4.60–22.53) were more likely to be diagnosed with syphilis. The prevalence of syphilis is high among MSM attending the HIV clinic in Trinidad, and most of these infections were asymptomatic; hence, targeted and sustained interventions to reduce syphilis transmission are urgently required. Repeat episodes of syphilis may play a role in the transmission dynamics of syphilis in MSM.

Pitfalls in the determination of intracranial spread of complicated suppurative sinusitis

1996 ◽  
Vol 110 (7) ◽  
pp. 673-675 ◽  
Author(s):  
B. J. Conlon ◽  
A. Curran ◽  
C. V. Timon
Keyword(s):  
Ct Scan ◽  
Previous History ◽  
Ct Scanning ◽  
Clinical Findings ◽  
Intracranial Extension ◽  
Sinus Disease ◽  
Grand Mal ◽  
History Of ◽  
Magnetic Resonance Imaging Mri

AbstractWe present two cases of suppurative sinusitis that presented to our casualty department over a one-week period. Both patients suffered complications of the disease secondary to extension of the inflammatory process beyond the bony confines of the sinus. Neither of the patients had a previous history of sinus disease. The first patient deteriorated suddenly 24 hours after admission. The initial computed tomography (CT) scan failed to demonstrate a developing subdural empyema. This complication was confirmed following repeat scanning 24 hours later and the patient required urgent neurosurgical intervention and drainage. The second patient presented with periorbital cellulitis secondary to sinusitis and suffered a grand mal seziure on admission. Once again initial CT scan changes were subtle and significant intracranial extension was not noted until the subsequent magnetic resonance imaging (MRI) scan was performed.The purpose of this paper is to highlight the potential dangers over reliance on CT scanning in diagnosing early intracranial spread of sinus disease and we emphasise that the clinician must interpret any radiological investigations in light of the associated clinical findings.

scholarly journals OCCURRENCE OF OBSTRUCTIVE AIRWAY DISEASE IN TREATED PATIENTS OF PULMONARY TUBERCULOSIS : A RETROSPECTIVE STUDY

2020 ◽  
pp. 1-2
Author(s):  
Shivprasad Kasat ◽  
Ashish Deshmukh ◽  
Sunil Jadhav ◽  
Hafiz Deshmukh ◽  
Ashish Kendre
Keyword(s):  
Pulmonary Tuberculosis ◽  
Previous History ◽  
Previous Treatment ◽  
Airway Disease ◽  
Clinical Findings ◽  
Obstructive Airway Disease ◽  
Medical College ◽  
Duration Of Illness ◽  
History Of ◽  
Obstructive Airway Diseases

Aim: To study occurence of obstructive airway disease in treated patients of pulmonary tuberculosis. Materials and methods: 50 patients data collected from Respiratory medicine department, MGM medical college, Aurangabad, who visited OPD for various respiratory symptoms. It is ensured that patients who are participated in the study are non smokers. Previous history of pulmonary tuberculosis and treatment history is noted. Evidences of previous treatment and radiological images were collected. Each patient was subjected to a thorough clinical examination and spirometry. Results: Based on clinical findings, radiological findings, and spirometry findings, of the 50 patients studied, it is observed that 11(22%) patients had developed obstructive airway disease.4 (8%) patients have developed extensive fibrosis post tuberculosis. 3 (6%) patients have developed cavitation with fibrosis. 4 (8%) patients have developed bronchiectasis. Conclusion: It is not uncommon that obstructive airway disease occurs as a complication of post tuberculosis sequale. 22 percent of the patients studied, have developed different types of obstructive airway diseases. Many factors may influence in post tuberculosis complications such as extensiveness of parenchymal involvement, duration of illness, socio-economic factors. Obstructive airway disease can be a sequel of pulmonary tuberculosis and should be overlooked, especially in those patients complaining of dyspnea even in the absence of any history of smoking. Post-tuberculous obstructive airway disease as a cause of COPD in nonsmokers should be now more recognized in countries where the prevalence of pulmonary tuberculosis is still high.

scholarly journals PROFILE OF THE PATIENTS WHO UNDERWENT PROLENE HERNIA SYSTEM EXTENDED FOR INGUINAL HERNIA IN A TEACHING INSTITUTE IN SUBHIMALAYAN REGION

2020 ◽  
pp. 1-2
Author(s):  
Rohit Kumar ◽  
Arvind Bhatia ◽  
Shelja Rawat ◽  
Ritu Rawat ◽  
Shikha Rawat ◽  
...  
Keyword(s):  
Inguinal Hernia ◽  
Surgical Repair ◽  
Previous History ◽  
Controlled Study ◽  
History Of Surgery ◽  
Indirect Hernia ◽  
Prolene Hernia System ◽  
Direct Hernia ◽  
History Of ◽  
Scrotal Swelling

Introduction: Worldwide, inguinal hernia repair is probably the most commonly performed general surgical procedure. Hence, a slight refinement of surgical repair of inguinal hernia would mean a substantial benefit to the patient. Aim: The study aimed to study profile of the patients who underwent Prolene Hernia System Extended (PHSE) for Inguinal Hernia in a teaching institute in Sub-Himalayan region. Materials and Methods: This was a controlled study conducted over 30 adult patients of both genders admitted at Dr RPGMC Tanda at Kangra from September 2016 to September 2017. Patients clinically diagnosed with inguinal hernias both direct and indirect on examination were enrolled in the trial after their informed consent. Results: Mean age of the patients was 54.9±13.66 years (range 30 to 80 years). 33% of the patients were elderly. All the patients were males. 43% of the patients were smokers and 53% were consuming alcohol. 20% of the patients had associated co-morbidities. 7% patients had previous history of surgery. Fifty percent of the patients had direct hernia while 33% had indirect hernia. Among 10% patients, it was bubonocele type. Seven patients had complications. Scrotal swelling was the most common welling (n=3) followed by inguinodynia (n=2), and seroma formation and urinary retention in one patient each. Conclusion: PHSE for management of inguinal hernia is associated with better outcomes.

scholarly journals Lipoma Arborescens of the Knee: Report of Three Cases and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Ioannis Tsifountoudis ◽  
Dimitrios Kapoutsis ◽  
Anastasios-Nektarios Tzavellas ◽  
Ioannis Kalaitzoglou ◽  
Apostolos Tsikes ◽  
...  
Keyword(s):  
Previous History ◽  
Young Male ◽  
Clinical Findings ◽  
Imaging Features ◽  
Lipoma Arborescens ◽  
History Of ◽  
Suprapatellar Pouch ◽  
Benign Nature ◽  
Slow Growing

Lipoma arborescens is a chronic, slow-growing, intra-articular lesion of benign nature, which is characterized by villous proliferation of the synovium, with replacement of the subsynovial connective tissue by mature fat cells. It usually involves the suprapatellar pouch of the knee joint. It is not a neoplasm but is rather considered a nonspecific reactive response to chronic synovial irritation, due to either mechanical or inflammatory insults. We report three cases of lipoma arborescens affecting the knee, the first in a young male without previous history of arthritis or trauma, the second in a 58-year-old male associated with osteoarthritis, and the final in a 44-year-old male diagnosed with psoriatic arthritis, which cover the entire pathologic spectrum of this unusual entity. We highlight the clinical findings and imaging features, by emphasizing especially the role of MRI, in the differential diagnosis of other, more complex intra-articular masses.

405: Previous History of Bladder Cancer is an Independent Prognostic Factor for Upper Tract Transitional Cell Carcinoma

2007 ◽  
Vol 177 (4S) ◽  
pp. 135-135
Author(s):  
Eiji Kikuchi ◽  
Akira Miyajima ◽  
Ken Nakagawa ◽  
Mototsugu Oya ◽  
Takashi Ohigashi ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Prognostic Factor ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Previous History ◽  
Independent Prognostic Factor ◽  
Upper Tract ◽  
History Of

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

Rhabdomyolysis in DOMS

1999 ◽  
Vol 38 (05) ◽  
pp. 164-168 ◽  
Author(s):  
Gloria Ruiz Hernandez ◽  
C. Sanchez Marchori ◽  
J. Munoz Moliner ◽  
C. Martinez Carsi
Keyword(s):  
Bone Scintigraphy ◽  
Previous History ◽  
Biochemical Studies ◽  
History Of ◽  
Increased Activity

SummaryA 26-year-old man with a previous history of external twin bursitis was remitted to our Department for a bone scintigraphy. Before the study, the patient performed an elevated number of intense sprints. Bone scintigraphy showed a bilaterally increased activity in both anterior rectum muscles suggesting rhabdomyolysis. Biochemical studies and MRT confirmed the diagnosis.

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