Syphilis among men who have sex with men attending a large HIV clinic in Trinidad

2021 ◽  
pp. 095646242199719
Author(s):  
Robert Jeffrey Edwards ◽  
Isshad John ◽  
Selena Todd ◽  
Leon-Omari Lavia ◽  
David Musa ◽  
...  

A chart review study was conducted to determine the prevalence of syphilis and explore the associated risk factors among men who have sex with men (MSM) who attended a large HIV clinic in Trinidad during the period January–December 2019. Patients were routinely screened for syphilis annually, and demographic, clinical, and laboratory data were extracted from the medical records. Descriptive and bivariate analyses were performed, and factors significantly associated with a syphilis diagnosis were assessed using multivariate logistic regression. During the period, 218 MSM were seen, age range 19–67 years, and median age 34.0 years. The prevalence of syphilis was 41.3% (90/218), and 71.1% (64//90) of these infections were asymptomatic. Multivariate analysis using logistic regression showed that MSM living with HIV in the 30–34 years old-age group (OR, 4.32; 95% CI, 1.04–18.02), and those with a previous history of treated syphilis (OR, 10.18; 95% CI, 4.60–22.53) were more likely to be diagnosed with syphilis. The prevalence of syphilis is high among MSM attending the HIV clinic in Trinidad, and most of these infections were asymptomatic; hence, targeted and sustained interventions to reduce syphilis transmission are urgently required. Repeat episodes of syphilis may play a role in the transmission dynamics of syphilis in MSM.

Author(s):  
Jeffrey Edwards ◽  
Avery Hinds ◽  
Nyla Lyons ◽  
Jonathan Edwards ◽  
Shauntelle Quammie ◽  
...  

A chart review study of the sexually transmitted infection (STI) prevalence among persons living with HIV (PLHIV) was conducted among STI clinic attendees in Trinidad between January 2012 and December 2012. Data were abstracted from client records to obtain the clinical and the laboratory diagnoses of STIs. Descriptive and bivariate analyses were conducted, and factors significantly associated with the presence of a STI were assessed using multiple logistic regression. During this period, 385 PLHIV were seen; 104 (27.0%) were newly HIV diagnosed and 281 (73.0%) had a known history of HIV infection; 135 (35.1%) were diagnosed with a STI. Patients with known HIV infection were more likely to be diagnosed with a STI than those who were newly diagnosed (odds ratios: 6.99; 95% confidence interval: 3.79-12.89). The STI prevalence was high among PLHIV in Trinidad, identifying them as a critical target group for public health interventions to prevent the spread of HIV and STIs.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Majid Moshirfar ◽  
Maylon Hsu ◽  
Julia Schulman ◽  
Joseph Armenia ◽  
Shameema Sikder ◽  
...  

Purpose. To assess the incidence of central serous chorioretinopathy (CSCR) following laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK).Methods. A chart review was performed to identify all patients with CSCR and a previous history of LASIK or PRK.Results. Over the 6-year study period, 1 of 4,876 eyes which had LASIK or PRK at the Moran Eye Center was diagnosed with CSCR. One other patient was referred from an outside center, developed CSCR symptoms one month after PRK. Both patients were managed conservatively with a final visual acuity of 20/20 or better. All other patients presented 4 or more years after refractive surgery.Conclusions. We report the first 2 CSCR cases developing within one month after PRK. The low incidence argues against a causal association. Topical corticosteroids or anxiety may elevate cortisol levels presenting therapeutic challenges for the management of CSCR after PRK or LASIK.


2011 ◽  
Vol 71 (6) ◽  
pp. 699-708
Author(s):  
Yan Song ◽  
Xiaoming Li ◽  
Liying Zhang ◽  
Yingjie Liu ◽  
Shulin Jiang ◽  
...  

Background: Sexually-transmitted disease (STD) is a facilitating cofactor that contributes to human immunodeficiency virus (HIV) transmission. Previous studies indicated a high prevalence of STDs among men who have sex with men (MSM) in China. To date, limited data are available for correlates of STD infection among young migrant MSM in China. The current study intends to examine the association between demographic and behavioral factors and STD infection. Methods: Data were collected from a sample of 307 migrant MSM aged 18–29 years in Beijing in 2009. Multivariate logistic regression analysis was employed to examine the factors associated with a history of STDs. Results: Results showed that about 13% of MSM reported a history of STDs. The average number of lifetime sexual partners was 15.0. About 56.7% of MSM did not use a condom at the first sexual encounter. The percentage of MSM who used a condom consistently was 47.4%. Multivariate logistic regression results showed that STD history was positively associated with education, income, the number of lifetime male sexual partners, and negatively associated with the frequency of properly using a condom. Conclusion: STD history was associated with socioeconomic status and sexual risk behaviors. The results suggested that HIV prevention intervention programs need to educate MSM to reduce the number of sexual partners and to use a condom properly. Furthermore, HIV prevention intervention programs among MSM need to be tailored to meet the needs of different socioeconomic groups of MSM.


2012 ◽  
Vol 6 (12) ◽  
pp. 860-869 ◽  
Author(s):  
Nenfort Edward Gomwalk ◽  
Lohya Nimzing ◽  
John Danjuma Mawak ◽  
Nimzing G. Ladep ◽  
Stephen B. Dapiap ◽  
...  

Introduction: Previous sentinel surveys of HIV in Nigeria studied pregnant women attending antenatal care, thereby omitting other important high-risk groups. We therefore investigated the prevalence of HIV/AIDS in low- and high-risk populations in the state of Plateau, Nigeria. Methodology: Blood samples were collected by venepuncture from 5,021 adults aged ≥15 years between August and October 2008. At least one major town and one rural community were selected in each Local Government Area (LGA). Samples were initially screened with a rapid HIV testing kit; reactive samples were further tested using Stat Pak.  Discordant samples were confirmed using Genie-II. Results: Of 5,021 subjects screened, 245 (4.88%) were seropositive. Local Government prevalence ranged from 0.68% in Bassa to 16.07% in Jos North. On average, LGAs in the Southern Senatorial Zone had higher rates. Most (over 80%) positive cases were younger than 40 years. Females had a significantly higher (6.85%) prevalence than males (2.72%). Age-specific prevalence was higher among females aged 25 to 29 years (2.09%). Risk factors identified  for acquisition of HIV infection were previous history of STDs (6, 16.28%); men having sex with men (2, 11.76%); having multiple sexual partners (97; 10.49%); intravenous drug use (10, 7.58%); sharing of sharp objects (20, 4.82%); and history of blood transfusion (21, 3.65%). Conclusion: The seemingly higher prevalence recorded in this survey could be attributed to the  inclusion of high- and low-risk groups in the general population, unlike previous reports which studied only antenatal care attendees. This survey provides useful baseline information for further studies.


Author(s):  
Ideh Ghafour ◽  
Forouzan Elyasi

Context: Neuroleptic malignant syndrome (NMS) has been introduced as a rare but lethal and idiosyncratic reaction to neuroleptics/antipsychotics. The most obvious risk of this syndrome is the use of neuroleptics, especially high-potency ones. Metoclopramide is also known as an anti-nausea medication administered before surgery to manage digestive problems. Evidence Acquisition: Formerly, it had been assumed that metoclopramide was a type of chlorobenzamide that was not in the phenothiazine group but free of extrapyramidal side effects (EPSs). The sequential reports of complications indicate that metoclopramide can cause EPSs and drug-induced motor side effects. A total number of 5044 articles were obtained after the initial search. Then, two researchers independently screened out their titles, and abstracts and 20 articles were finally selected based on the inclusion criteria. Results: Of the 20 articles reporting metoclopramide-induced NMS, treatments had been successful in 16 (80%) cases, but it had led to death in four (20%) patients. There were 11 and 8 male and female patients, respectively, and gender was not mentioned for a patient in one article. The age range of the patients was from six months to 84 years, and the mean age was 50.92 years. Conclusions: Although NMS following metoclopramide intake is reported very rarely, it should be considered for any psychiatric symptoms with unexpected mental changes, muscle rigidity, and fever after being treated with metoclopramide. The neuroleptic malignant syndrome can occur following multiple doses or just one dose of metoclopramide. Also, metoclopramide use in patients affected with kidney failure is accompanied by a higher risk of NMS. A previous history of NMS, a recent episode of catatonia, and severe agitation are all taken into account as risk factors in this domain.


2020 ◽  
Vol 24 (1) ◽  
Author(s):  
Tolesa Neggasa ◽  
Feyissa Begna ◽  
Moti Wakgari ◽  
Sisay Shibashi ◽  
Eshetu Gezahegn ◽  
...  

Contagious bovine pleuropneumonia (CBPP) remains a huge threat to cattle production in sub Saharan African countries in general and in Ethiopia in  particular. A cross sectional study was conducted between November, 2017 and June, 2018 to estimate the seroprevalence and associated risk factors of CBPP in the Gudeya Bila and Boneya Boshe districts of East Wollega Zone, Oromia Regional State. The study was conducted on 384 cattle with no history of vaccination against CBPP, using systematic random sampling technique. Blood samples were collected from the jugular vein of each animal and tested by competitive ELISA. Information on risk factors influencing the occurrence of CBPP was collected using questionnaire survey. Data obtained from both serological and questionnaire surveys were analyzed by using SPSS software version 20. Logistic regression was used to analyze the association of exposure variables with anti-mycoplasma mycoides subspecies small colony antibodies. The results indicated that, the overall seroprevalence of CBPP at individual animal-level and herd-level was 8.6% and 26.3%, respectively. There was a statistically significant association in the sero-prevalence of Mycoplasma mycoides subsp. mycoides SC (MMmsSC) antibody (P< 0.05) with the poor body condition score, origin of animals (purchasing from outside of herd) and previous history of CBPP disease at individual animal and large herd size at herd level. This study showed that the overall prevalence of CBPP in study area was high. This warrants the implementation of appropriate preventive and control practice. Keywords: Boneya Boshe, Bovine, CBPP, c-ELISA, Ethiopia, Gudeya Bila, Sero-prevalence


2017 ◽  
Vol 8 (1) ◽  
pp. 17-22
Author(s):  
Habib Ahmed ◽  
Ferdousi Rahman ◽  
Mahbubur Rahman ◽  
Mohammad Enamul Karim ◽  
Sayeda Rahim ◽  
...  

Background: In Bangladesh self-poisoning cases are mostly of organophosphorous compound (OPC). It is documented that 14% of all deaths amongst 10 to 50 year old women in Bangladesh were due to poisoning, the majority following suicidal ingestion of pesticides. In tertiary level hospital, a large number of self-poisoning cases are of different pharmaceutical agents, mostly from urban areas and mostly of teenager group. So the trend of self-poisoning is different in urban area than that of rural area. These pharmaceutical agent self-poisoning cases admitted into the hospitals have different modalities of clinical features with variable outcomes and socioeconomic background. But there is no actual data of these self-poisoning by the different pharmaceutical agents. Therefore, this study was aimed to describe the pattern of self-poisoning by different pharmaceutical agents.Methods: A descriptive longitudinal study was conducted in five adult medicine units of a tertiary level hospital from January 2008 to June 2008. All self-poisoned patients with different pharmaceutical agents were included with their prior informed written consent. A pre-tested questionnaire was used for data collection.Results: A total of 281 patients were interviewed. Most of the patients were female (70.8%) with highest age range from 13 to 30 years (91.81%). Most of the patients were students (53%) and 40.9% were secondary school certificate pass. 60.1% patients were unmarried. Most of the patients were from urban area (84%). The commonest background for self-poisoning was family disharmony (74.46%). Most common offending pharmaceutical agents were benzodiazepines (44.10%), collected mostly from local dispensary without prescription (89.33%). Most of the patients consulted within 1 to 2 hours of poisoning (44.5%). Commonest consultation before admission was in a Government hospital (48.40%). Only 3 patients (1.10%) were known to have psychiatric illness. Five patients (1.80%) had previous history of self-poisoning. Most of the patients (89.3%) stayed in the hospital for 1 day with no mortality.Conclusion: Self poisoning by pharmaceutical agents is common especially in urban areas. Common offending pharmaceutical agents were benzodiazepines. The commonest background for self-poisoning was family disharmony.J Shaheed Suhrawardy Med Coll, June 2016, Vol.8(1); 17-22


Author(s):  
Muhammad B. Aminu ◽  
Mohammed Alkali ◽  
Bala M. Audu ◽  
Toyin Abdulrazak ◽  
Dauda Bathna

Background: One of the commonest symptoms observed in pregnant women before the 20th week of gestation is nausea and vomiting, an exaggeration of these symptoms hyperemesis gravidarum (HEG) could result in maternal and fetal catastrophes and even death. The objective of this study was to determine the prevalence and associated risk factors for hyperemesis gravidarum among pregnant women at booking.Methods: A prospective institutional based study design was done among 452 pregnant women seen at booking in a tertiary hospital in Northeast Nigeria from the 1st February 2019 to 30th June 2019. Data was summarized using descriptive statistics. OR was used to measure significant risk.Results: The observed prevalence of hyperemesis gravidarum among pregnant women in the study is 44.9%. The Majority (81.4%) of these women were between the age range of 21 and 35 years. Mean age of 27 years. Multiparity (33.4%), previous (44.9%) and family history of HEG (31.6%) were identified as important risk factors for developing HEG. Grand multiparity (11.5%) and gestational age less than 13 weeks (6.64%) were however less likely observed to be risks for HEG.Conclusions: HEG is a common problem in pregnancy with almost half of the number of pregnant women at booking affected. Multiparity and past history of HEG are pointers to developing the condition and it should be looked out for among at risk group of pregnant women, so that early intervention can be instituted to avoid any possible adverse outcome.


2019 ◽  
Vol 71 (3) ◽  
pp. 473-479 ◽  
Author(s):  
Tomohiko Koibuchi ◽  
Michiko Koga ◽  
Tadashi Kikuchi ◽  
Taizo Horikomi ◽  
Yoshihiro Kawamura ◽  
...  

Abstract Background Hepatitis A virus (HAV) can be sexually transmitted. However, the level of HAV immunity among patients living with human immunodeficiency virus (HIV) in Japan is unknown. Determining the epidemiology of HAV infections among men who have sex with men (MSM) and who are living with HIV is essential for an HAV vaccination program. This study examined HAV immunity in patients living with HIV and applied the decision-tree analysis to explore the factors of immunoglobulin G (IgG)-hepatitis A (HA) antibodies in MSM living with HIV. Methods We examined the presence of IgG-HA antibodies among patients living with HIV from January to December 2017 in The Hospital of The Institute of Medical Science, The University of Tokyo. We recorded each patient’s age, sex, mode of HIV transmission, year of HIV diagnosis, HAV vaccine status, history of HAV infection, and history of other infectious diseases. A decision-tree algorithm was used to reveal the factors and profiles most relevant to the anti-HAV prevalence. Results Overall, 378 MSM patients living with HIV were examined for IgG-HA antibodies. After excluding 24 patients who had received a HAV vaccine, the data of 354 MSM were analyzed (median age 45 years, interquartile range 39–51 years). Of the 354 patients, 60 (16.9%) were positive for IgG-HA antibodies. The HA positivity rate increased with patients’ age, and age (&gt; 63.5 years) was extracted as the most important variable by classification of the decision-tree algorithm. Conclusions Our study, conducted just before the HAV outbreak among MSM in Tokyo, showed that age was the most relevant factor in anti-HAV prevalences. An extensive HAV vaccination program for MSM patients living with HIV is urgently needed, particularly for younger people.


Infectio ◽  
2018 ◽  
Vol 23 (1) ◽  
pp. 92
Author(s):  
Pedro Luis Martinez-Iglesias ◽  
Jaime Enrique Ruiz-Sternberg ◽  
Sebastian León-Leiva ◽  
Claudia Catalina Beltran-Rodriguez ◽  
Mónica María Rojas-Rojas ◽  
...  

Objective: To determine the prevalence of comorbidities among adults living with HIV from two healthcare centers in Colombia, and to identify factors associated with comorbidity-free years.Methods: Observational, retrospective medical chart review study. Summary statistics for demographic and clinical characteristics were developed and relationship between comorbidity-free years were analyzed through Kaplan-Meier analysis and Cox regression.Results: 669 clinical charts were included, 71.7% were male and 16.1% were 50 years or older, 69.96% had at least one comorbidity. The most frequent comorbidities were dislipidemia(15.06%), hypertension(5.67%), risk factors were tobacco use(15.33%), alcohol intake(24.36%) and drugs abuse (14.66%).Discussion: These findings are consistent with previous reports showing the underlying processes of patients, producing multiple comorbidities.Conclusions: Significant proportion of patients have comorbidities that may increase risk of other complications or reduced comorbidity-free years. Poly-pharmacy among HIV+ adults need to be addressed to ensure adherence and minimize drug-drug interactions.


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