Understanding Cytokines Part II: Implications for Nursing Research and Practice

2000 ◽  
Vol 2 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Elizabeth J. Corwin

Cytokines are small signaling proteins released from a variety of cells that influence virtually every aspect of growth and development and every host response to infection, injury, and inflammation. Because of their widespread and potent effects across the life span, cytokines without a doubt influence nursing research and practice. From physiological and adaptive effects of cytokines to cytokine-induced diseases, nurses and nursing care are involved. Part II of this review highlights a few of the many examples of cytokines functioning in response to infection and inflammation, during the processes of reproduction, and in a variety of pathophysiological states. Implications for nursing research and practice are emphasized.

2010 ◽  
Author(s):  
Erica Frydenberg ◽  
Krys Kaniasty ◽  
Erica Frydenberg ◽  
Barbara Jones ◽  
Esther Greenglass ◽  
...  

2021 ◽  
Vol 34 (2) ◽  
pp. 209-210
Author(s):  
Mi Jin Doe

The author in this article provides the introduction to the review of Peterson and Bredow’s 5th edition of Middle Range Theories: Application to Nursing Research and Practice.


2021 ◽  
Vol 34 (2) ◽  
pp. 211-216
Author(s):  
Howard K. Butcher

The author in this article provides a review of Peterson and Bredow’s 5th edition of Middle Range Theories: Application to Nursing Research and Practice. The author also shared some concerns and thoughts about the current status of nursing theory and middle-range theory.


2021 ◽  
Vol 22 (11) ◽  
pp. 5655
Author(s):  
Heather Jackson ◽  
Stephanie Menikou ◽  
Shea Hamilton ◽  
Andrew McArdle ◽  
Chisato Shimizu ◽  
...  

The aetiology of Kawasaki disease (KD), an acute inflammatory disorder of childhood, remains unknown despite various triggers of KD having been proposed. Host ‘omic profiles offer insights into the host response to infection and inflammation, with the interrogation of multiple ‘omic levels in parallel providing a more comprehensive picture. We used differential abundance analysis, pathway analysis, clustering, and classification techniques to explore whether the host response in KD is more similar to the response to bacterial or viral infections at the transcriptomic and proteomic levels through comparison of ‘omic profiles from children with KD to those with bacterial and viral infections. Pathways activated in patients with KD included those involved in anti-viral and anti-bacterial responses. Unsupervised clustering showed that the majority of KD patients clustered with bacterial patients on both ‘omic levels, whilst application of diagnostic signatures specific for bacterial and viral infections revealed that many transcriptomic KD samples had low probabilities of having bacterial or viral infections, suggesting that KD may be triggered by a different process not typical of either common bacterial or viral infections. Clustering based on the transcriptomic and proteomic responses during KD revealed three clusters of KD patients on both ‘omic levels, suggesting heterogeneity within the inflammatory response during KD. The observed heterogeneity may reflect differences in the host response to a common trigger, or variation dependent on different triggers of the condition.


2019 ◽  
Vol 39 (2) ◽  
pp. 5-18
Author(s):  
Elizabeth M. Higgins ◽  
Susan M. Campbell

Virginia Gordon was a teacher, scholar, practitioner, and leader who also served as a role model and mentor to others. Her insight and research informed the many innovative initiatives she pursued on behalf of the student advising experience. Gordon's scholarly and evidence-based approach set the stage for academic advising as a field of scholarly inquiry and helped shape the growth and direction of the profession. Virginia Gordon's work was other-directed. Her goal was always to support the growth and development of others. This qualitative study tried to capture Gordon as understood by the higher education professionals who knew her, worked with her, and/or studied with her. That she was other-directed supports our view regarding Virginia Gordon as a servant leader.


2020 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
Fabrice Mbakop Kwefeu

The frequent closure of roads for the sake of maintenance and refurbishment is an increasing problem for the road administrators and users, because of induced high costs, restrictions and influence they impose, traffic jam, and the many other disruptions such interventions have on traffic. In these circumstances, carriageways with long life span, with adapted tar, have much to offer, especially if they can exhibit optimum performances without requiring major repairs for over 30 years. On high traffic roads, research have shown that binders with elevated modules are a reliable and credible alternative to render their life span more sustainable and durable. In this context, the advantages presented by the absence of important repairs and refurbishing can be enough to justify the initial high costs of these advanced carriage way coatings. Studies on the different binders to be used were done, which have permitted in accordance with the performance of the layers, the required tests and the different study levels. Also, this has permitted us to analyze the obtained results and conclude that due to the expected needs, the LA and MDE tests, the PSV tests are the criteria that determine the selection of aggregates; The complexes modular methods, fatigue resistance (level IV), seem to be necessary for the forecasting of the mechanical behavior of bituminous materials.


2022 ◽  
pp. 167-186
Author(s):  
Isabel Maria Abreu Rodrigues Fragoeiro

The text is based on the scientific research carried out by the author during the many years that she has tried to follow the evolution of mental health at an international level, in Portugal and in the Autonomous Region of Madeira. It is based on the knowledge deepened through critical reflection carried out throughout the training and professional processes in which it has participated. The performance as a professor at the University of Madeira-Health Higher School, the real experience as a provider of specialized nursing care in mental and psychiatric health to population groups living in different communities, the various intervention contexts in which mental healthcare is available, the different circumstances of health and illness observed in people who experience transactional and adaptive processes at various stages of the life cycle are real contributions that have been constituted as a source of essential material for a critical and constructive look at one of the great challenges that health and mental health services and their professionals face in today's societies.


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