31. Comparison of the Motor Recovery in Patients with Subcortical and Cortical Stroke: Inpatient Rehabilitation to Three Years Post Stroke Bruce T. Volpe (White Plains, New York), H. I. Krebs (Cambridge, Massachusetts), N. Hogan (Cambridge, Massachusetts), L. Edelstein (White Plains, New York), C. Diels (White Plains, New York), and Mindy L. Aisen (Washington, DC

1999 ◽  
Vol 13 (1) ◽  
pp. 28-29
Keyword(s):  
New York ◽  
Inpatient Rehabilitation ◽  
Motor Recovery ◽  
Washington Dc ◽  
Post Stroke ◽  
Cortical Stroke

Abstract TMP42: Coherent Neural Oscillations Inform Early Stroke Motor Recovery

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Jessica M Cassidy ◽  
Anirudh Wodeyar ◽  
Ramesh Srinivasan ◽  
Steven C Cramer
Keyword(s):  
Primary Motor Cortex ◽  
Inpatient Rehabilitation ◽  
Functional Independence ◽  
Motor Recovery ◽  
Neural Oscillations ◽  
Lasso Regression ◽  
Post Stroke ◽  
Eeg Power ◽  
High Beta ◽  
Early Stroke

Introduction: Neural oscillations may contain valuable information for stroke rehabilitation. The objective of this study was to examine the predictive performance of neural oscillations in early stroke motor recovery using dense array electroencephalography (EEG). Since past work theorizes that neural oscillations underlie behavior, we hypothesized that coherent oscillations with ipsilesional primary motor cortex (M1) across a 1-30 Hz band would significantly predict early motor recovery post-stroke. Methods: Individuals with stroke admitted to an inpatient rehabilitation facility (IRF) completed a three-minute resting EEG recording and structural MRI around the time of IRF admission and motor testing (Functional Independence Measurement motor subscale (FIM-motor)) at IRF admission and discharge. We examined how well FIM-Motor change was predicted using EEG power and coherence with ipsilesional M1 across delta (1-3 Hz), theta (4-7 Hz), alpha (8-12 Hz), low beta (13-19 Hz), and high beta (20-30 Hz) frequency bands, along with corticospinal tract (CST) injury, in a lasso regression with K-fold cross-validation for deviance estimation. Results: Twenty-seven subjects (20 males, 58.3±14.6 years, 8-17 days post-stroke) with predominantly mild-moderate motor impairment participated. EEG ipsilesional M1 coherence with 16 leads overlying both hemispheres predicted 61.8% of FIM-motor change from IRF admission to discharge, with higher frequencies (alpha, high beta) positively relating to motor recovery. Lower frequencies overlying contralesional parietal (theta) and frontal (delta) regions inversely and positively related to motor recovery respectively. Coherence outperformed EEG power and CST injury measurements. Ipsilesional M1 coherence also predicted 55.2% of the variance in residuals derived from a predictive model containing only CST injury, suggesting that EEG coherence and CST injury contain unique information for motor recovery prediction. Conclusions: Early after stroke, coherence of neural oscillations with ipsilesional M1 across the entire brain through a wide frequency spectrum is best at predicting functional gains from inpatient rehabilitation and may be feasible as a bedside biomarker of motor recovery.

More than motor impairment: A spatiotemporal analysis of cognitive impairment and associated neuropathological changes following cortical photothrombotic stroke

2021 ◽  
pp. 0271678X2110058
Author(s):  
Sonia Sanchez-Bezanilla ◽  
Rebecca J Hood ◽  
Lyndsey E Collins-Praino ◽  
Renée J Turner ◽  
Frederick R Walker ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Motor Impairment ◽  
Amyloid Β ◽  
Neuronal Loss ◽  
Spatiotemporal Analysis ◽  
Motor Recovery ◽  
Experimental Stroke ◽  
Post Stroke ◽  
Cortical Stroke ◽  
Photothrombotic Stroke

There is emerging evidence suggesting that a cortical stroke can cause delayed and remote hippocampal dysregulation, leading to cognitive impairment. In this study, we aimed to investigate motor and cognitive outcomes after experimental stroke, and their association with secondary neurodegenerative processes. Specifically, we used a photothrombotic stroke model targeting the motor and somatosensory cortices of mice. Motor function was assessed using the cylinder and grid walk tasks. Changes in cognition were assessed using a mouse touchscreen platform. Neuronal loss, gliosis and amyloid-β accumulation were investigated in the peri-infarct and ipsilateral hippocampal regions at 7, 28 and 84 days post-stroke. Our findings showed persistent impairment in cognitive function post-stroke, whilst there was a modest spontaneous motor recovery over the investigated period of 84 days. In the peri-infarct region, we detected a reduction in neuronal loss and decreased neuroinflammation over time post-stroke, which potentially explains the spontaneous motor recovery. Conversely, we observed persistent neuronal loss together with concomitant increased neuroinflammation and amyloid-β accumulation in the hippocampus, which likely accounts for the persistent cognitive dysfunction. Our findings indicate that cortical stroke induces secondary neurodegenerative processes in the hippocampus, a region remote from the primary infarct, potentially contributing to the progression of post-stroke cognitive impairment.

Quản trị quốc gia và những gợi mở cho tiến trình cải cách thể chế kinh tế thị trường ở việt nam

2018 ◽  
Vol 34 (1) ◽  
Author(s):  
Nguyen Manh Hung
Keyword(s):  
New York ◽  
World Bank ◽  
Sustainable Growth ◽  
Sub Saharan Africa ◽  
Viet Nam ◽  
Washington Dc ◽  
World Development Report ◽  
The World Bank ◽  
The World ◽  
World Development

Trong khoảng 10 - 15 năm gần đây, ở Việt Nam đã nổi lên luận điểm rằng: cải cách thể chế kinh tế ngày càng đóng vai trò quan trọng hơn trong tiến trình đổi mới. Khi các nguồn lực như tài nguyên thiên nhiên, lao động giá rẻ và vốn...đã đến giới hạn thì cải cách thể chế trở thành đòi hỏi tất yếu đối với nền kinh tế. Tuy nhiên, đây cũng là thử thách khó khăn của quá trình phát triển. Trên thế giới, nhiều quốc gia chỉ đạt được một phần mục tiêu của cải cách, thậm chí ở một số quốc gia nỗ lực cải cách thể chế lại đẩy nền kinh tế vào những bất ổn không ngừng.  Tiến trình cải cách thể chế kinh tế sẽ khó thể thành công nếu không đi kèm với nỗ lực thiết lập một nền tảng quản trị quốc gia vững mạnh. Từ khóa Quản trị, thể chế, kinh tế thị trường, cải cách References [1] Acemoglu, Daron and James Robinson (2012). Why Nations Fail: The Origins of Power, Prosperity, and Poverty. Random House[2] Acemoglu, Daron, Simon Johnson and James A. Robinson (2001), “The Colonial Origins of Comparative Development: An Empirical Investigation” The American Economic Review Vol. 91, No. 5 (Dec., 2001)[3] Acemoglu, Daron, Simon Johnson and James Robinson (2005). “Institutions as Fundamental Cause of Long run Growth”, Handbook ofEconomic Growth, Volume IA. Edited by Philippe Aghion and Steven N. Durlauf. 2005 Elsevier B.V[4] Asian Development Bank (1995). Governance: Sound Development Management, October 1995;[5] Diễn đàn kinh tế tư nhân Việt Nam 2016: Cơ hội, thách thức và giải pháp. Hà nội,[6] Heritage Foundation (2017). 2017 Index of Economic Freedom,[7] [http://www.heritage.org/index/ranking][8] International Development Association (1998). Additions to IDA Resources: Twelfth Replenishment (IDA12). 23 December 1998; [9] Kasper, Wolfgang and Manfred E Streit (1999). Institutional Economics: Social Order and Public Policy, Edward Elgar. Tr. 41[10] Kaufmann, Daniel; Aart Kraay, Massimo Mastruzzi (2010), The Worldwide Governance Indicators Methodology and Analytical Issues, the World Bank Policy Research Working Paper 5430, September 2010[11] Nguyễn Quang Thuấn (2017). “Cải thiện nền quản trị quốc gia, tạo môi trường thuận lợi thúc đẩy tăng trưởng kinh tế trong giai đoạn tới”, tham luận tại Diễn đàn Kinh tế Việt Nam 2017: Phát huy nội lực, tăng trưởng bền vững, Ban kinh tế trung ương ngày 27/06/2017[12] North, D.C. (1990), Institutions, Institutional Change and Economic Performance, Cambridge and New York: Cambridge University Press.[13] Osborne, S. P. (2006), “The New Public Governance?” Public Management Review, vol. 8, No. 3, pp. 377-388.[14] UNDP (1997). “Governance for Sustainable Human Development” New York; WB (1994). Governance: The World Bank’s Experience. Washington DC; [15] VCCI & USAID (2015). Báo cáo năng lực cạnh tranh cấp tỉnh năm 2015. Hà Nội: Phòng Thương mại và Công nghiệp Việt Nam và Cơ quan Phát triển Quốc tế Hoa Kỳ [16] Wolfensohn, James D. (1999), Address to the Board of Governors (September 28, 1999), the World Bank[17] WB (1992). World Development Report: Governance and Development, Washington DC. [18] WB (1989). Sub-Saharan Africa: From Crisis to Sustainable Growth, Washington DC[19] WB (2016). Ease of Doing Business 2016. Washington DC [20] http://www.doingbusiness.org/data/exploreeconomies/vietnam[21] WB (1997). World Development Report 1997. Washington DC. [22] WB (2017). Worldwide Governance Indicator, [23] http://info.worldbank.org/governance/wgi/index.aspx#reports[24] World Economic Forum (2016). Global Competitiveness Report 2016-2017, Geneva.

scholarly journals Post-Stroke Depression and Its Effect on Functional Outcomes during Inpatient Rehabilitation

2021 ◽  
Author(s):  
Gurumayum Sonachand Sharma ◽  
Anupam Gupta ◽  
Meeka Khanna ◽  
Naveen Bangarpet Prakash
Keyword(s):  
Outcome Measures ◽  
Functional Outcomes ◽  
Rating Scale ◽  
Tertiary Care ◽  
Depression Scale ◽  
Inpatient Rehabilitation ◽  
University Hospital ◽  
Post Stroke ◽  
Significant Difference ◽  
Post Stroke Depression

Abstract Objective The aim of the study is to observe the effect of post-stroke depression on functional outcomes during inpatient rehabilitation. Patients and Methods The design involved is prospective observational study. The location involved is Neurological Rehabilitation unit in a tertiary care university hospital. The study period ranges from October 2019 to April 2020. The participants involved are the patients with first ever stroke, male and female with age ≥18 years and duration less than 1 year. All participants were assessed at admission and after 14 sessions of inpatient rehabilitation by depression subscale of Hospital Anxiety and Depression Scale (HADS-D) and Hamilton Depression Rating Scale (HDRS). The stroke outcomes measures used were: Barthel Index (BI), Scandinavian Stroke Scale (SSS), and Modified Rankin Scale (MRS). Results There are a total of 30 participants (18 males) with median stroke duration of 90 days. The median age of the patients was 58 years. Sixteen patients had ischemic and 14 had hemorrhagic stroke. Out of these, 57% (n = 17) had symptoms of depression (HADS-D >7). Participants in both groups (with and without depression) showed improvement in all the functional outcome measures (BI, SSS, MRS) at the time of discharge as compared with admission scores. The changes in the outcome measures were statistically significant within groups (p < 0.05) but not significant between the groups (p > 0.05). Conclusion The post-stroke depression is common among stroke survivors of less than 1 year duration. There was no significant difference in the functional outcomes between stroke patients with depression and those without depression with inpatient rehabilitation program.

RAGE!, Retaliation, and Retribution: Recurring Themes in August Wilson’s Work

2021 ◽  
Vol 52 (5) ◽  
pp. 482-508
Author(s):  
Kimmika Williams-Witherspoon
Keyword(s):  
New York ◽  
Public Discourse ◽  
Washington Dc ◽  
The Public ◽  
Resistance Strategies ◽  
Black Bodies ◽  
Black Rage ◽  
Historical Moment ◽  
Equity And Inclusion ◽  
Movement Activist

Following the murders of George Floyd, Breonna Taylor and so many others, recent protest in Minneapolis, New York, Philadelphia, Chicago, Washington, DC, LA, Portland and a host of other locations, both, stateside and abroad are being framed in the public discourse as everything from radical resistance to public madness and everything in between. From the Black Lives Matter movement activist to Diversity, Equity, and Inclusion advocates, one of the key components in, both, radical resistance strategies or public expressions of cultural madness, is a ground swelling of rage! But what is rage? How can we recognize it? Historically, what has been the consequences of Black rage? And in this unique, historical moment, what if anything can be done to leverage it? Mining August Wilson’s work for definitions, instances, and consequences of Black rage, this paper interrogates August Wilson’s narratives on rage as a way to talk about the historiography and commodifying of Black rage as a way of victimizing and disposing of Black bodies in America. In this way, we hope to offer suggestions in this historical moment on how to leverage Black rage, rather than to be snared by it.

Ustilago syntherismae. [Descriptions of Fungi and Bacteria].

1995 ◽  
Author(s):  
J. E. M. Mordue
Keyword(s):  
New York ◽  
North Carolina ◽  
South Carolina ◽  
South Dakota ◽  
Sierra Leone ◽  
Geographical Distribution ◽  
New Hampshire ◽  
Far East ◽  
Washington Dc ◽  
Loose Smut

Abstract A description is provided for Ustilago syntherismae. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: Digitaria spp., including D. filiformis, D. ischaemum, D. sanguinalis. DISEASE: Loose smut of Digitaria. Infection sometimes dwarfs the host and causes it to branch more profusely than usual (36, 657); it is also reported that vegetative vigour is much prolonged in infected plants compared with uninfected (30, 432). Surface contamination by the large number of ustilospores when shed may result in some discolouration of the entire inflorescence including sheaths and leaf blades. GEOGRAPHICAL DISTRIBUTION: Africa: 'Congo', Gambia, Kenya, Sierra Leone, South Africa, Sudan, Uganda, Zambia, Zimbabwe; Asia: Azerbaijan, China, Republic of Georgia, India, Japan, Pakistan, Russia (central Asia, far east); Australasia: Australia: NSW (31, 225); Europe: Bulgaria, Czechoslovakia, Denmark (39, 284), Germany, Hungary, Italy, Poland, Portugal, Romania, Russia (European region), Ukraine (52, 354); North America: Canada (Ontario; 46, 3383), Mexico, USA (Alabama, Arkansas, California, Connecticut, Washington DC, Delaware, Florida, Georgia, IA, Illinois, Indiana, Kansas, Kentucky, Louisiana, Maine, MD, ME, Michigan, Montana, Missouri, MS, North Carolina, Nebraska, New Hampshire, New Jersey, New York, Ohio, Oklahoma, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Virginia; 69, 2765); South America: Argentina, Brazil, Uruguay. (33, 634; 40, 209; 48, 2203; 50, 2756; 64, 4163). TRANSMISSION: No detailed studies have been reported; ustilospores are presumably disseminated by air currents and infection is thought to be systemic.

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