Cystic adventitial disease of the popliteal artery: Two case reports and a review of the literature

Two cases of cystic adventitial disease treated at our institution over the last year are presented. They were middle-aged and apparently healthy patients, and the symptoms begin with a sudden onset of unilateral claudication. After performing a magnetic resonance angiography, a cystic formation attached to the adventitia of the popliteal artery was identified. Both patients were treated in the same manner, with resection of the affected arterial segment and vein bypass interposition. Both remain asymptomatic after one year of follow-up in one case and six months in the other. Cystic adventitial disease is a rare entity, which presents in patients without cardiovascular risk factors, so sometimes it takes long to reach a definitive diagnosis. Concerning the different treatment options, cyst excision together with the affected arterial segment seems to offer better mid- and long-term results when compared with other treatment options such as cyst aspiration or endovascular techniques, although there are no multicenter trials evidencing the superiority of one against the others.

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Sertoli-Leydig Cell Tumor with Concurrent Rhabdomyosarcoma: Three Case Reports and a Review of the Literature

Case Reports in Medicine ◽

10.1155/2017/4587296 ◽

2017 ◽

Vol 2017 ◽

pp. 1-6 ◽

Cited By ~ 3

Author(s):

Trisha Plastini ◽

Arthur Staddon

Keyword(s):

Leydig Cell ◽

Malignant Tumors ◽

Case Reports ◽

Treatment Options ◽

Treatment Strategies ◽

Salvage Chemotherapy ◽

Response To Chemotherapy ◽

One Year ◽

Lost To Follow Up

Sertoli-Leydig Cell Tumors (SLCTs) make up <1% of all ovarian tumors and are benign or malignant, androgen-secreting tumors. Rhabdomyosarcoma (RMS) is a heterogeneous group of malignant tumors that resemble developing skeletal muscle. There have been case reports of patients with concurrent SLCT and RMS with limited treatment options. We aim to demonstrate treatment strategies used in our patients, which seemed to have prolonged survival when compared to prior case reports of patients not cured by surgical resection. Herein we describe 22 cases of SLCT with RMS elements as discussed in prior case reports and three cases from the authors’ institution. Of the 19 cases from prior case reports, five were lost to follow-up and two had NED after surgical intervention. Eleven patients had recurrence and were deceased within one year. Of those patients not surgically cured, only three patients were documented as living beyond two years, all of whom received chemotherapy. The three patients presented from our institution had clinical evidence of response to chemotherapy that is traditionally used for RMS. In conclusion, chemotherapy with doxorubicin and ifosfamide has activity in patients with SLCT and RMS as does salvage chemotherapy with vincristine, irinotecan, and temozolomide.

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Celebrating one year anniversary of Contemporary Pediatric Dentistry and introducing the new Congress

Contemporary Pediatric Dentistry ◽

10.51463/cpd.2021.2 ◽

2021 ◽

Vol 2 (3) ◽

pp. 134-134

Author(s):

Burak Buldur

Keyword(s):

Case Reports ◽

Treatment Options ◽

Pediatric Dentistry ◽

Good News ◽

International Congress ◽

Original Research ◽

Virtual Meeting ◽

Health Quality ◽

One Year

Hi Dear Friends and Colleagues, I am pleased to inform you some of good news regarding the development and process of the Contemporary Pediatric Dentistry (CPD). Since its establishment, CPD has received 80 submissions from all over world within sixteen months, and published 25 articles including review, original research and case reports. CPD has also moved to be indexed in reputed databases. Another achievement was establishment of 1st International Congress of Contemporary Pediatric Dentistry (ICCPD), organized by the CPD, which was taken place on 1- 3 November 2021 as a fully virtual meeting to celebrate the first anniversary of the launch of CPD. The ICCPD hosted 257 registered colleagues from 47 countries. The website of the ICCPD had been viewed more than 5000 visitors from 102 countries in only 2 months. As an exciting action, CPD is now getting ready to initiate the 2nd International Congress of Contemporary Pediatric Dentistry (www.iccpd.org). I feel confident that the ICCPD 2022 will serve as a place of learning where we can all share the latest knowledge and learn the contemporary view, approaches, techniques and treatment options from highly eminent clinicians and/or academicians from different countries. The theme of the ICCPD 2022 is “Contemporary Clinical Techniques in Pediatric Dentistry”. The 2nd ICCPD will also host oral and poster presentation. All abstracts will be published in the Supplementary Issue of Contemporary Pediatric Dentistry. It is my honor to invite all colleagues, who have sincere enthusiasm to help children to let them have better oral health, quality of life, smiling and development, to attend 2nd International Congress of Contemporary Pediatric Dentistry to be held on 2-4 September 2022 as a fully virtual meeting. Please follow website and social media accounts of CPD to get latest information regarding Congress and the Journal.

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Hypertelorism

Indian Journal of Plastic Surgery ◽

10.4103/0970-0358.146572 ◽

2014 ◽

Vol 47 (03) ◽

pp. 284-292 ◽

Cited By ~ 7

Author(s):

Ramesh K. Sharma

Keyword(s):

Case Reports ◽

Treatment Options ◽

Timing Of Surgery ◽

Long Term Results ◽

Illustrative Case ◽

Normal Position ◽

Vertical Orientation ◽

Underlying Condition ◽

Choice Of Procedure

ABSTRACTThe term orbital hypertelorism (ORH) implies “widely apart orbits.” This may also be associated with the abnormal vertical orientation of the orbits (dystopia). This deformity may be unilateral or bilateral, symmetric or asymmetric and may be present in a variety of craniofacial conditions. The treatment is primarily carried out for aesthetic reasons. The timing of treatment is dictated by the underlying condition and the type of procedure envisaged. The mainstay of treatment consists of moving the orbits medially to near normal position. This is accomplished by either an orbital translocation or facial bipartition technique. The choice of procedure is governed by the shape of the maxillary arch and associated occlusal conditions. We must differentiate between the telecanthus (also called pseudo-hypertelorism) and a true ORH as the management differs in these two conditions. The ORH involves extensive intracranial and extracranial operation whereas the telecanthus correction is relatively simpler surgery. The article will discuss the aetiology, classification, presentation, treatment options, timing of surgery and the choice of surgical procedures. Illustrative case reports with long-term results will be used to explain the management of these patients.

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Surgical Treatment of Cystic Adventitial Disease of the Popliteal Artery: Five Case Reports

Case Reports in Vascular Medicine ◽

10.1155/2015/984681 ◽

2015 ◽

Vol 2015 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

Kimihiro Igari ◽

Toshifumi Kudo ◽

Takahiro Toyofuku ◽

Yoshinori Inoue

Keyword(s):

Popliteal Artery ◽

Case Reports ◽

Case Series ◽

Vascular Reconstruction ◽

Transluminal Angioplasty ◽

Treatment Modalities ◽

Invasive Treatment ◽

Cyst Aspiration ◽

The Subject ◽

Percutaneous Transluminal

Cystic adventitial disease (CAD) is a rare cause of intermittent claudication and nonatherosclerotic conditions in middle-aged men without cardiovascular risk factors. The etiology of CAD is unclear; however, the direct communication between a cyst and a joint is presumed to be a cause. We herein report a case series of CAD of the popliteal artery (CADPA), in which patients were treated with surgical resection and vascular reconstruction. Although less invasive treatment modalities, including percutaneous cyst aspiration and percutaneous transluminal angioplasty, have been the subject of recent reports, these treatments have had a higher recurrence rate. Therefore, all of the CAPDA cases in the present series were treated surgically, which lead to good outcomes.

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Three year results of endovascular therapy with a new generation nitinol stent for femoro-popliteal artery lesions - a single-center outcome analysis of a subcohort of MISAGO 2 study

VASA ◽

10.1024/0301-1526/a000299 ◽

2013 ◽

Vol 42 (5) ◽

pp. 340-349 ◽

Cited By ~ 9

Author(s):

Ivan Kralj ◽

Irene Boos ◽

Uwe Müller-Bühl

Keyword(s):

Popliteal Artery ◽

Clinical Success ◽

Ankle Brachial Index ◽

Long Term Results ◽

Outcome Analysis ◽

Stent Fracture ◽

Nitinol Stent ◽

New Generation ◽

Stent Stenosis

Background: Advances in stent technology have widened the field of indications for stent treatment of femoro-popliteal artery lesions, however the use of stents in bending arterial segments is restricted because some first- and second-generation nitinol stent designs did not respond well to the mechanical forces of femoro-popliteal segments in motion which pose a substantial risk of stent fracture inducing in-stent-stenosis. New generation nitinol stents are supposed to overcome these limitations but long-term results are rare. Patients and methods: In forty-five patients (mean age 68 y, range 50 - 85) with peripheral arterial disease (TASC II A-C, Rutherford category 2 - 5) forty-six lesions of the superficial femoral artery (37) or popliteal artery (9) were treated [25 high-grade stenoses, mean length 53 mm (range 30 - 145 mm); 21 chronic total occlusions, mean length 74 mm (range 30 - 180 mm)]. 74 % of lesions were located in the mobile bending arterial segments in the distal femoral or the popliteal segment. Clinical reevaluation performed at discharge, at 6, 12, 24, and 36 months included at least the measurement of ankle-brachial index (ABI) and duplex sonography. Results: Procedural success rate was 100 %. At 6, 12, 24, and 36 months, cumulative primary patency rate was 93.5 %, 84.8 %, 80.5 %, and 74.3 % (SE<10); freedom from target lesion revascularization rate was 95.7 %, 89.2 %, 84.9 %, and 79.3 % (SE<10); Rutherford category and ABI improved in all patients and clinical success was maintained in more than 85 % of patients. Conclusions: Sustained technical and clinical success and good clinical long-term results were achieved with Misago™ nitinol stent implantation in femoro-popliteal lesions with moderate risk for in-stent-stenosis, and in the distal femoral and popliteal mobile segment.

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Preventing Premature Weaning: Management Options for Common Lactation Conditions, Including OMT

Osteopathic Family Physician ◽

10.33181/12012 ◽

2020 ◽

pp. 20-25

Author(s):

Denise Sackett ◽

Tala Dajani ◽

David Shoup ◽

Uzoma Ikonne

Keyword(s):

Postpartum Depression ◽

Family Physician ◽

Treatment Options ◽

World Health ◽

Management Options ◽

Pharmacological Management ◽

Control And Prevention ◽

Lactational Mastitis ◽

One Year ◽

Health Organization

The benefits of breastfeeding are well established. The World Health Organization and the Centers for Disease Control and Prevention recommend that mothers breastfeed infants for at least one year, but most children are not breastfed that long because of many factors. Breastfeeding mothers face many challenges to continued breastfeeding, including medical conditions that arise during this period, such as postpartum depression and lactational mastitis. Because of a perceived lack of consistent guidance on medication safety, it can be difficult for the family physician to treat these conditions while encouraging mothers to continue breastfeeding. The purpose of the current review is to summarize and clarify treatment options for the osteopathic family physician treating lactating mothers. We specifically focus on the pharmacological management of contraception, postpartum depression, and lactational mastitis.

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Acute Limb Ischaemia Following Elective Left Upper Lobectomy for Early NSCLC: A Rare but Serious Complication Arising from the Pulmonary Vein Stump

10.31487/j.crss.2020.01.02 ◽

2020 ◽

pp. 1-2

Author(s):

James Elliott ◽

Anand Iyer ◽

James Elliott

Keyword(s):

Pulmonary Vein ◽

Ct Angiography ◽

Mediastinal Lymph Node ◽

Case Reports ◽

Common Femoral Artery ◽

Sudden Onset ◽

Leg Pain ◽

Limb Ischaemia ◽

Left Upper Lobectomy ◽

Acute Limb Ischaemia

Patients undergoing Left Upper Lobectomy (LUL) appear to be at risk of a unique post-operative complication that is not well-documented: Pulmonary Vein (PV) stump thrombosis +/- systemic arterial embolisation [1-3]. We describe the details of a rare case from our institution, present a review of this subject from the limited literature available, and suggest potential strategies to anticipate, detect and manage this entity. A 70 year old female patient underwent left upper lobectomy and mediastinal lymph node sampling via repeat left thoracotomy. The procedure was unremarkable apart from some adhesions. She progressed well post-operatively on the ward. On post-operative day 2 the patient developed sudden-onset left leg pain and paraesthesia and CT-Angiography confirmed the diagnosis of left common femoral artery embolus and left superior PV stump thrombosis. The patient returned to theatre for femoral embolectomy, continued systemic anticoagulation, and made an excellent recovery thereafter. The aetiology of this complication has been documented in some case reports, but it is not explored further in trials or thoracic surgery texts [2-3]. One cohort study involving CT-angiography after lobectomy surgeries found that left upper lobectomy was unique as a risk factor for PV stump thrombosis1. It may be related to the relatively longer LSPV stump and stasis of blood in the stump [4].

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Characteristics and Treatment Challenges of Non-Clear Cell Renal Cell Carcinoma

Cancers ◽

10.3390/cancers13153807 ◽

2021 ◽

Vol 13 (15) ◽

pp. 3807

Author(s):

Pierangela Sepe ◽

Arianna Ottini ◽

Chiara Carlotta Pircher ◽

Andrea Franza ◽

Melanie Claps ◽

...

Keyword(s):

Renal Cell ◽

Kinase Inhibitors ◽

Clear Cell ◽

Case Reports ◽

Treatment Options ◽

Single Agent ◽

Growth Factor Receptor ◽

Mtor Inhibitors ◽

Cell Renal Cell Carcinoma ◽

Clear Cell Rcc

Non-clear cell renal cell carcinomas (RCC) comprise several rare and poorly described diseases, often characterized by bad prognosis and with no standard treatments available. The gap in their clinical management is linked to the poor molecular characterization in handling the treatment of non clear-cell RCC with untailored therapies. Due to their rarity, non-clear RCC are in fact under-represented in prospective randomized trials. Thus, treatment choices are based on extrapolating results from clear cell RCC trials, retrospective data, or case reports. Over the last two decades, various options have been considered as the mainstay for the treatment of metastatic RCC (mRCC), including angiogenesis inhibitors, vascular endothelial growth factor receptor inhibitors, other tyrosine kinase inhibitors (TKIs), as well as MET inhibitors and mammalian targeting of rapamycin (mTOR) inhibitors. More recently, the therapeutic armamentarium has been enriched with immunotherapy, alone or in combination with targeted agents that have been shown to significantly improve outcomes of mRCC patients, if compared to TKI single-agent. It has been widely proven that non-clear cell RCC is a morphologically and clinically distinct entity from its clear cell counterpart but more knowledge about its biology is certainly needed. Histology-specific collaborative trials are in fact now emerging to investigate different treatments for non-clear cell RCC. This review summarizes pathogenetic mechanisms of non-clear cell RCC, the evolution of treatment paradigms over the last few decades, with a focus on immunotherapy-based trials, and future potential treatment options.

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Squamous cell carcinoma of the scrotum in HIV: two case reports

African Journal of Urology ◽

10.1186/s12301-021-00177-3 ◽

2021 ◽

Vol 27 (1) ◽

Author(s):

Jeff John ◽

Ken Kesner ◽

John Lazarus

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Case Reports ◽

Treatment Options ◽

Punch Biopsy ◽

Delayed Treatment ◽

Clinical Presentations ◽

T1 N0 M0

Abstract Background Squamous cell carcinoma (SCC) of the scrotum was the first malignancy known to be associated with exposure to an occupational carcinogen—in this case, soot trapped in the breeches of chimney sweeps. Better civil rules and regulations and the replacement of hearths with other forms of heating have rendered SCC of the scrotum a rarity. We report two cases of scrotal SCC with vastly differing clinical presentations and management. Case presentation Case 1 had T1 N0 M0 disease and presented with a small (< 2 cm), innocuous-looking, non-healing ulcer of eight years duration. A punch biopsy revealed a superficially invasive SCC confirmed on immunohistochemical profiling. A wide local excision of the lesion was subsequently performed. Follow-up at three years showed no signs of recurrence. Case 2 presented with T4 N1 M1 disease and rapidly progressing locally destructive mass. A punch biopsy of the scrotal lesion confirmed invasive moderately differentiated focally keratinising SCC. The metastatic evaluation confirmed the presence of metastatic, extensive para-aortic lymphadenopathy. He was managed with cisplatin-based chemoradiotherapy. Conclusion Early detection and management of patients with SCC of the scrotum are essential. If the diagnosis is delayed, treatment options become limited, and the prognosis is poor. Notwithstanding the rarity of this disease, multicentre trials are needed to provide more precise guidelines as to the optimal management of these patients.

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Management of Amelogenesis Imperfecta in Childhood: Two Case Reports

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18137204 ◽

2021 ◽

Vol 18 (13) ◽

pp. 7204

Author(s):

Mirja Möhn ◽

Julia Camilla Bulski ◽

Norbert Krämer ◽

Alexander Rahman ◽

Nelly Schulz-Weidner

Keyword(s):

Case Reports ◽

Treatment Options ◽

Permanent Dentition ◽

Amelogenesis Imperfecta ◽

Structural Defects ◽

Type I ◽

Oral Rehabilitation ◽

Self Confidence ◽

Health Quality ◽

Masticatory System

Amelogenesis imperfecta (AI) is defined as an interruption of enamel formation due to genetic inheritance. To prevent malfunction of the masticatory system and an unaesthetic appearance, various treatment options are described. While restoration with a compomer in the anterior region and stainless steel crowns in the posterior region is recommended for deciduous dentition, the challenges when treating such structural defects in mixed or permanent dentition are changing teeth and growing jaw, allowing only temporary restoration. The purpose of this case report is to demonstrate oral rehabilitation from mixed to permanent dentition. The dentition of a 7-year-old patient with AI type I and a 12-year-old patient with AI type II was restored under general anesthesia to improve their poor aesthetics and increase vertical dimension, which are related to problems with self-confidence and reduced oral health quality of life. These two cases show the complexity of dental care for structural anomalies of genetic origin and the challenges in rehabilitating the different phases of dentition.

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