scholarly journals Respiratory-tract infections among geriatrics: prevalence and factors associated with the treatment outcomes

2021 ◽  
Vol 15 ◽  
pp. 175346662097114
Author(s):  
Ali Akhtar ◽  
Mohamed Azmi Ahmad Hassali ◽  
Hadzliana Zainal ◽  
Irfhan Ali ◽  
Muhammad Shahid Iqbal ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Treatment Outcomes ◽  
Respiratory Tract Infections ◽  
Community Acquired Pneumonia ◽  
Chronic Obstructive ◽  
Medication Regimen ◽  
Cross Sectional ◽  
Factors Associated ◽  
Medication Regimen Complexity ◽  
Tract Infections

Background: Geriatric individuals are more susceptible to different infections, especially respiratory-tract infections (RTIs) due to their compromised immune system. Hence, the objectives of the present study were to evaluate the prevalence, medication regimen complexity and factors associated with the treatment outcomes of different RTIs among geriatrics. Methods: A retrospective cross-sectional study (5 years) was conducted at the respiratory department, Hospital Pulau Pinang. Patients aged ⩾65 years with confirmed diagnosis of RTI were included in the study. Results: A total of 474 patients were included, and the most prevalent RTIs were community-acquired pneumonia (65.6%) followed by chronic obstructive pulmonary disease (20.7%), bronchitis (8.2%) and hospital-acquired pneumonia (5.5%). Amoxicillin/clavulanate (69.8%), ampicillin/sulbactam (9.1%) and cefuroxime (6.5%) are the most common antibiotics prescribed to treat RTIs among geriatrics. Smoking, alcohol consumption, polypharmacy and presence of other co-morbidities are statistically significant factors associated with treatment outcomes of RTIs among geriatrics. Conclusion: Prevalence of community-acquired pneumonia (65.6%) among older patients aged 65 years and older higher than other RTIs. Smoking, alcohol use, presence of polypharmacy and other co-morbidities are important factors associated with the treatment outcomes of RTIs. The reviews of this paper are available via the supplemental material section.

scholarly journals A Cross-Sectional Assessment of Urinary Tract Infections Among Geriatric Patients: Prevalence, Medication Regimen Complexity, and Factors Associated With Treatment Outcomes

2021 ◽  
Vol 9 ◽  
Author(s):  
Ali Akhtar ◽  
Mohamed Azmi Ahmad Hassali ◽  
Hadzliana Zainal ◽  
Irfhan Ali ◽  
Amer Hayat Khan
Keyword(s):  
Older Adults ◽  
Urinary Tract ◽  
Treatment Outcomes ◽  
Medication Regimen ◽  
Cross Sectional ◽  
Factors Associated ◽  
Medication Regimen Complexity ◽  
Regimen Complexity ◽  
Study Population ◽  
Tract Infections

Background: Urinary tract infections (UTIs) are the second most prevalent infection among the elderly population. Hence, the current study aimed to evaluate the prevalence of UTIs among older adults, medication regimen complexity, and the factors associated with the treatment outcomes of elderly patients infected with UTIs.Methods: A retrospective cross-sectional study was conducted at the Department of Urology, Hospital Pulau Pinang, Malaysia. The patients ≥65 years of age were included in the present study with a confirmed diagnosis of UTIs from 2014 to 2018 (5 years).Results: A total of 460 patients met the inclusion criteria and were included in the present study. Cystitis (37.6%) was the most prevalent UTI among the study population followed by asymptomatic bacteriuria (ASB) (31.9%), pyelonephritis (13.9%), urosepsis (10.2%), and prostatitis (6.4%). Unasyn (ampicillin and sulbactam) was used to treat the UTIs followed by Bactrim (trimethoprim/sulfamethoxazole), and ciprofloxacin. The factors associated with the treatment outcomes of UTIs were gender (odd ratio [OR] = 1.628; p = 0.018), polypharmacy (OR = 0.647; p = 0.033), and presence of other comorbidities (OR = 2.004; p = 0.002) among the study population.Conclusion: Cystitis is the most common UTI observed in older adults. Gender, the burden of polypharmacy, and the presence of comorbidities are the factors that directly affect the treatment outcomes of UTIs among the study population.

scholarly journals Study on Knowledge and Practices of Ayurvedic Preventive Measures for Respiratory Tract Infections

2021 ◽  
pp. 29-37
Author(s):  
B. L. Edirisinghe ◽  
W. M. S. S. K. Kulathunga
Keyword(s):  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Preventive Measures ◽  
Good Practice ◽  
World Health ◽  
Survey Study ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
The Mean ◽  
Tract Infections

Respiratory diseases have become world health burden. It has been estimated that 65 million people have moderate severe chronic obstructive pulmonary diseases from which about 3 million die each year. Objective of this survey study was to assess knowledge and practice of Intern medical officers on Ayurvedic preventive measures for managing respiratory tract infectious diseases. A cross sectional descriptive study was carried out among the Intern Medical Officers during their training program. 85 respondents out of 150 were assessed for their knowledge and practices on Ayurvedic preventive measures for Respiratory tract infections by using pre-structured questionnaire. Among the sampled students, most of them were female 92.9% (79) and unmarried 51.8% (44). The mean age and the standard deviation of the respondents were 28.25 + 0.815 years. There were 41(48.2%) Intern medical students with good knowledge, 42(49.4%) were with satisfactory knowledge and 2.4% of the study group was having the little knowledge. Most of the respondents 56(65.9%) were doing good practice on preventing RTI and 29 (34.1%) respondents were doing bad practice. Overall the respondents have good practice on prevention of RTI with the mean score of 19.9 + 2.589.

scholarly journals Appropriate antibiotic management of bacterial lower respiratory tract infections

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1121 ◽  
Author(s):  
Charles Feldman ◽  
Guy Richards
Keyword(s):  
Respiratory Tract ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Empiric Therapy ◽  
Community Acquired Pneumonia ◽  
Chronic Obstructive ◽  
Lower Respiratory Tract Infections ◽  
Pneumococcal Infections ◽  
Obstructive Pulmonary Disease ◽  
Tract Infections

Lower respiratory tract infections are the leading cause of infectious disease deaths worldwide and are the fifth leading cause of death overall. This is despite conditions such as pneumococcal infections and influenza being largely preventable with the use of appropriate vaccines. The mainstay of treatment for the most important bacterial lower respiratory tract infections, namely acute exacerbations of chronic obstructive pulmonary disease (AECOPD) and community-acquired pneumonia (CAP), is the use of antibiotics. Yet despite a number of recent publications, including clinical studies as well as several systematic literature reviews and meta-analyses, there is considerable ongoing controversy as to what the most appropriate antibiotics are for the empiric therapy of CAP in the different settings (outpatient, inpatient, and intensive care unit). Furthermore, in the case of AECOPD, there is a need for consideration of which of these exacerbations actually need antibiotic treatment. This article describes these issues and makes suggestions for appropriately managing these conditions, in the setting of the need for antimicrobial stewardship initiatives designed to slow current emerging rates of antibiotic resistance, while improving patient outcomes.

scholarly journals Knowledge about hypertension and factors associated with the non-adherence to drug therapy

2014 ◽  
Vol 22 (3) ◽  
pp. 491-498 ◽  
Author(s):  
Mayckel da Silva Barreto ◽  
Annelita Almeida Oliveira Reiners ◽  
Sonia Silva Marcon
Keyword(s):  
Drug Therapy ◽  
Healthcare Service ◽  
Cross Sectional Study ◽  
Medication Regimen ◽  
Cross Sectional ◽  
Poor Knowledge ◽  
Factors Associated ◽  
Medication Regimen Complexity ◽  
Hypertensive Drug ◽  
Complex Drug

OBJECTIVES: to identify the degree of knowledge of people with hypertension concerning the disease and to verify the factors associated with the non-adherence to anti-hypertensive drug therapy.METHOD: Cross sectional study, involving 422 people. Data collection took place at their homes, between December 2011 and March 2012, through interviews using the following instruments: Medication Adherence Questionnaire (MAQ-Q), Medication Regimen Complexity Index (MRCI) and a guide with questions related to sociodemographic profile, satisfaction with healthcare service and knowledge about the disease.RESULTS: 42.6% did not adhere to the drug therapy and 17.7% had poor knowledge about the disease. Factors associated with the non-adherence were: complex drug therapy, poor knowledge about the disease and dissatisfaction with the healthcare service.CONCLUSION: The findings reinforce that the complex drug therapy prescriptions, little knowledge about the disease and dissatisfaction with the healthcare service have influence on the process of non-adherence to anti-hypertensive drug therapy.

Reappraisal of respiratory syncytial virus as an aetiology of severe acute lower respiratory tract infections in children younger than 5 years in Nigeria

2019 ◽  
Vol 113 (8) ◽  
pp. 446-452
Author(s):  
Damilola M Oladele ◽  
Dimeji P Oladele ◽  
Rasheedat M Ibraheem ◽  
Mohammed B Abdulkadir ◽  
Rasaki Adewole Raheem ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Respiratory Tract ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Preventive Strategy ◽  
Lower Respiratory Tract Infections ◽  
Cross Sectional ◽  
Rsv Infection ◽  
Syncytial Virus ◽  
Tract Infections

Abstract Background Acute lower respiratory tract infections (ALRIs) especially severe ALRIs, constitute a global high burden of morbidity and mortality in children <5 y of age and respiratory syncytial virus (RSV) has been documented to a play a major aetiological role. However, Nigerian reports on severe childhood RSV ALRIs are rare and most reports are old. With recent advances in RSV preventive strategy, arises the need for a recent appraisal of RSV infection in children with severe ALRI. The current study thus set out to determine the prevalence of RSV infection among hospitalized children <5 y of age and describe the related social determinants. Methods We performed a descriptive cross-sectional study conducted over 1 y of 120 children, ages 2–59 months, diagnosed with ALRI. Relevant data were obtained and an antigen detection assay was used for viral studies. Results The prevalence of RSV infection was 34.2% and its peak was in the rainy months. The proportion of infants in the RSV-positive group was significantly higher than that in the RSV-negative group (82.9% vs 54.4%; p=0.002). These findings were largely consistent with those of earlier reports. Conclusions RSV has remained a common cause of severe ALRI in infants, especially during the rainy months in Nigeria. It is thus suggested that more effort be focused towards implementing the current global recommendations for the prevention of RSV-associated LRI, particularly in infants.

scholarly journals A cross sectional study on prescription pattern of drugs in upper respiratory tract infections in a tertiary care hospital

2020 ◽  
Vol 9 (2) ◽  
pp. 271
Author(s):  
Divya Bade ◽  
Shivashankaramurthy K. G. ◽  
Kiran L. J. ◽  
Raghuprasada M. S. ◽  
Harishkumar V. S. ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Cross Sectional Study ◽  
Prescribing Patterns ◽  
Essential Medicines ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Cross Sectional ◽  
Upper Respiratory ◽  
Tract Infections

Background: Upper respiratory tract infections are one of the leading causes of hospital visits worldwide. Judicious use of antibiotics is challenging for upper respiratory tract infections (URTIs) in developing countries like India. This leads to inappropriate use of antibiotics causing many dreaded conditions like antibacterial resistance among other things. Hence rational use of drugs, mainly antibacterial, is a priority to reduce the burden of treatment failure. The objective of this study is to study the prescribing patterns and rationality of drugs prescribed in the management of URTIs.Methods: This was a cross-sectional study. Data was collected from records of 300 outpatients clinically diagnosed as URTIs from SSIMS and RC Hospital, Davangere between January 2015 and June 2016. The prescribing patterns, approval status and listing of drugs in World Health Organization (WHO) essential medicines list/ National List of Essential Medicines (NLEM) were analysed. The data was presented as percentages, mean and standard deviations.Results: A total of 300 cases were studied. Among these, acute pharyngitis (29%) and acute sinusitis (26%) are the most common infections. Of the 300 cases studied, 283 (94.3%) were prescribed antimicrobials. Of the total 740 medications prescribed, 393 (53.1%) were fixed-dose combinations (FDCs). A total of 724 medications (97.8%) were approved by Drugs Controller General of India and 248 (33.5%) by Food and Drug Administration. Only 5.8% of the prescribed drugs have been listed in WHO’s and NLEM. The most common class of antibacterials prescribed was Beta-lactams.Conclusions: Oral formulations were preferred over parenteral formulations and FDCs were preferred over single drug formulations. Beta-lactams comprised the major class of antibacterial prescribed.

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