scholarly journals Pharmacotherapeutic approach toward urological medications and vaccination during COVID-19: a narrative review

2021 ◽  
Vol 13 ◽  
pp. 175628722110467
Author(s):  
Mojtaba Shafiekhani ◽  
Anahita Dehghani ◽  
Mina Shahisavandi ◽  
Seyed Ali Nabavizadeh ◽  
Maryam Kabiri ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Kidney Transplantation ◽  
Prostatic Hyperplasia ◽  
Narrative Review ◽  
The Novel ◽  
Urologic Diseases ◽  
One Year ◽  
Novel Coronavirus ◽  
Comprehensive Study

One year after the prevalence of the novel coronavirus pandemic, some aspects of the physiopathology, treatment and progression of coronavirus 2019 disease (COVID-19) have remained unknown. Since no comprehensive study on the use of urological medications in patients with COVID-19 has been carried out, this narrative review aimed to focus on clinically important issues about the treatment of COVID-19 and urologic medications regarding efficacy, modifications, side effects and interactions in different urologic diseases. In this review, we provide information about the pharmacotherapeutic approach toward urologic medications in patients with COVID-19 infection. This study provides an overview of medications in benign prostatic hyperplasia, prostate cancer, impotence and sexual dysfunction, urolithiasis, kidney transplantation and hypertension as the most frequent diseases in which the patients are on long-term medications. Also, the effect of urologic drugs on the efficacy of vaccination is briefly discussed.

scholarly journals Outpatient management of heart valve disease following the COVID-19 pandemic: implications for present and future care

Heart ◽  
2020 ◽  
Vol 106 (20) ◽  
pp. 1549-1554 ◽  
Author(s):  
Benoy Nalin Shah ◽  
Dominik Schlosshan ◽  
Hannah Zelie Ruth McConkey ◽  
Mamta Heena Buch ◽  
Andrew John Marshall ◽  
...  
Keyword(s):  
Heart Valve ◽  
Waiting Times ◽  
Severe Disease ◽  
Valve Disease ◽  
Heart Valve Disease ◽  
The Novel ◽  
Future Care ◽  
Novel Coronavirus

The established processes for ensuring safe outpatient surveillance of patients with known heart valve disease (HVD), echocardiography for patients referred with new murmurs and timely delivery of surgical or transcatheter treatment for patients with severe disease have all been significantly impacted by the novel coronavirus pandemic. This has created a large backlog of work and upstaging of disease with consequent increases in risk and cost of treatment and potential for worse long-term outcomes. As countries emerge from lockdown but with COVID-19 endemic in society, precautions remain that restrict ‘normal’ practice. In this article, we propose a methodology for restructuring services for patients with HVD and provide recommendations pertaining to frequency of follow-up and use of echocardiography at present. It will be almost impossible to practice exactly as we did prior to the pandemic; thus, it is essential to prioritise patients with the greatest clinical need, such as those with symptomatic severe HVD. Local procedural waiting times will need to be considered, in addition to usual clinical characteristics in determining whether patients requiring intervention would be better suited having surgical or transcatheter treatment. We present guidance on the identification of stable patients with HVD that could have follow-up deferred safely and suggest certain patients that could be discharged from follow-up if waiting lists are triaged with appropriate clinical input. Finally, we propose that novel models of working enforced by the pandemic—such as increased use of virtual clinics—should be further developed and evaluated.

scholarly journals The coronavirus in the MENA region: Enhancing turbulence or mitigating conflicts?

European View ◽  
2020 ◽  
Vol 19 (2) ◽  
pp. 206-211
Author(s):  
Magnus Norell
Keyword(s):  
Middle East ◽  
The Novel ◽  
Crisis Preparedness ◽  
Mena Region ◽  
Existing Problems ◽  
Regional Conflicts ◽  
Current Trends ◽  
Short And Long Term ◽  
Novel Coronavirus

The novel coronavirus (COVID-19) pandemic has affected the countries in the Middle East and North Africa (MENA) region in different ways, and the varying political structures, economic conditions and civil-crisis preparedness of the states in this region have resulted in it being handled in a variety of ways too. Even if it is difficult to assess how the crisis has affected the MENA region in more detail due to the region’s general volatility and ongoing conflicts in Libya and Syria, current trends have so far not shown a diminution in regional conflicts. Nor have the pandemic’s consequences in the Middle East lessened Europe’s problems with the region. Thus the article argues that COVID-19 has not really led to a decrease in the conflicts and wars plaguing the MENA region, and that, therefore, the effects for Europe—both short- and long-term—will still be felt, as existing problems will continue to affect Europe.

scholarly journals Long-Term Clinical Outcomes of Patients with no-significant of Transplanted Renal Artery Stenosis  

2021 ◽  
Author(s):  
Manoela Linhares Machado Barteczko ◽  
Henry Campos Orellana ◽  
Gustavo Rocha Feitosa Santos ◽  
Attílio Galhardo ◽  
Gabriel Kanhouche ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Kidney Transplantation ◽  
Renal Artery ◽  
Renal Artery Stenosis ◽  
Deceased Donor ◽  
Vascular Complication ◽  
Artery Stenosis ◽  
One Year

Abstract Background: Transplant Renal Artery Stenosis (TRAS) is the main vascular complication of kidney transplantation. For research and treatment purposes, several authors consider critical renal artery stenosis to be greater than 50%, and percutaneous intervention is indicated in this scenario. However, there are no reports in the current literature on the evolution of patients with less than 50% stenosis.Method: Retrospective study includes data from all patients that were submitted to kidney transplantation and were suspected TRAS after transplantation with stenosis under 50% independent on age, who were referred for angiography at a single center between January 2007 and December 2014. Results: During this period, 6,829 kidney transplants were performed at Hospital do Rim, 313 of them had clinical suspicion of TRAS and 54 were those who presented no-significant stenosis. The average age was 35.93 years old, the predominant gender was male and most individuals (94.4%) were submitted to dialysis before transplantation. Transplants, in most cases in this group, occurred from a deceased donor, 66.7%. The time between transplantation and angiography was less than one year in 79.6% of patients and all presented no-significant TRAS. Creatinine levels, Systolic Blood Pressure, Diastolic Blood Pressure and the glomerular filtration rate improved over the long term. The outcomes found were death and renal loss.Conclusion: Age, sex and ethnic group of patients are factors that did not interfere with the frequency of renal artery stenosis. The outcomes showed that in the long term most patients evolve well, and have improved quality of life and kidney function, although there are cases of death and kidney loss.

scholarly journals COVID-19 Pandemic: Impact of Quarantine on Medical Students’ Mental Wellbeing and Learning Behaviors

2020 ◽  
Vol 36 (COVID19-S4) ◽  
Author(s):  
Sultan Ayoub Meo ◽  
Dr Abdulelah Adnan Abukhalaf ◽  
Ali Abdullah Alomar ◽  
Kamran Sattar ◽  
David C Klonoff
Keyword(s):  
Medical Students ◽  
Work Performance ◽  
Mental Wellbeing ◽  
Psychological Wellbeing ◽  
The Novel ◽  
Learning Behaviors ◽  
Creative Commons ◽  
Novel Coronavirus ◽  
The Impact

Background and Objectives: The novel coronavirus COVID-19 pandemic causes great public health and socioeconomic harms. Worldwide many countries implemented quarantine policies to minimize the spread of this highly contagious disease. The present study aim was to investigate the impact of quarantine on the medical students’ mental wellbeing and learning behaviors. Methods: In this descriptive study, we used a questionnaire with a Five-Point Likert Scale to collect the information. The questionnaire was distributed among 625 medical students through their emails with a response rate of 530 (84.8%), majority 294 (55.47%) being female. The survey questionnaire consisted of total 20 items; 12 items were related to psychological wellbeing and stress-allied queries and 08 items were about learning behaviors. Results: The findings encompass two important characteristics related to quarantine, psychological wellbeing, and learning behaviors. A combined cohort of 234 medical students, either female or male, (which was 44.1% of the total responders) showed a sense of being emotionally detached from family, friends and fellow students, 125/ 530 (23.5%) medical students felt disheartened. Both female and male medical students showed a marked decrease in their overall work performance. Moreover, 56.2% of the total students (61.5% of the females and 49.5% of the males) felt a decrease in the time they spent studying. Conclusions: Both female and male medical students have identified that quarantine has caused them to feel emotionally detached from family, fellows, and friends and decrease their overall work performance and study period. The findings also show that one-fourth of the medical students who participated in this study felt disheartened during the quarantine period. The long-term quarantine due to COVID-19 pandemic may causes further worsening in the psychological and learning behaviors of these medical students. doi: https://doi.org/10.12669/pjms.36.COVID19-S4.2809 How to cite this:Meo SA, Abukhalaf AA, Alomar AA, Sattar K, Klonoff DC. COVID-19 Pandemic: Impact of Quarantine on Medical Students’ Mental Wellbeing and Learning Behaviors. Pak J Med Sci. 2020;36(COVID19-S4):---------. doi: https://doi.org/10.12669/pjms.36.COVID19-S4.2809 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals THE INFLUENCE OF CHRONIC DISEASES ON THE MANIFESTATION OF COVID-19 INFECTION

2021 ◽  
pp. 126-132
Author(s):  
S. O. Yastremska ◽  
O. M. Krekhovska-Lepiavko ◽  
B. A. Lokay ◽  
O. V. Bushtynska ◽  
S. V. Danchak
Keyword(s):  
Chronic Diseases ◽  
Case Fatality ◽  
The Novel ◽  
Fatality Rate ◽  
The World ◽  
Control And Prevention ◽  
The Usa ◽  
Life Threatening ◽  
One Year ◽  
Novel Coronavirus

Summary. The first known case of infection from the novel coronavirus was recorded almost one year ago, in China’s Hubei province. The city of Wuhan was infamous the world over as the original virus epicenter, seeing more than half of China’s reported cases and deaths. The outbreak of COVID-19 virus, as sickened more than 14.7 million people. At least 610.200 people have died. The aim of the study – to analyze and systematize the literature data about the influence of chronic diseases on the manifestation of COVID-19 infection. Materials and Methods. The study uses publications of the world scientific literature on COVID-19 infection, in particular the causes and mechanisms of its development, treatment, complications and its consequences as well as the influence of different chronic disorders on the course of COVID-19. Results. A sample of patients hospitalized with COVID-19 across 14 states of the USA in March was analyzed by The Centers for Disease Control and Prevention. It was found that many (89 %) had underlying health problem and 94 % of patients were at the age 65 and older. The case fatality rate for those under age 60 was 1.4 percent. For those over age 60, the fatality rate jumps to 4.5 percent. The older the population, the higher the fatality rate. For those 80 and over, Covid-19 appears to have a 13.4 percent fatality rate. Moreover, it was recognized, that older adults don't present in a typical way of the course of different disorders, and we're seeing that with Covid-19 as well. Conclusions. Chronic diseases and conditions are on the rise worldwide. COVID-19 became the most challenging pandemic influencing all countries worldwide. Chronic diseases are suggested to be one of the main causes of different life-threatening complications of COVID-19 infection and one of the main factors of poor prognosis for the patients.

scholarly journals Formulating a Scalable Approach to Patron-Requested Digitization in Archives

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Kevin S. Hawkins ◽  
Julie Judkins
Keyword(s):  
Risk Assessment ◽  
Copyright Law ◽  
The Novel ◽  
Long Distance ◽  
Novel Coronavirus ◽  
Distance Travel ◽  
Long Distance Travel

The novel coronavirus of 2019 (COVID-19) crisis has forced archives to rethink their modes of providing access to physical collections. Whereas difficult copyright questions raised by reproducing items could previously be skirted by requiring researchers to work with materials in person, the long-term closure of reading rooms and decrease in long-distance travel mean that archives need a workflow for handling user digitization requests that is scalable and requires consulting only easily identifiable information and, assuming full reproduction is off the table, reproducing items in a collection under 17 U.S.C. § 108 or through a strategy of rapid risk assessment. There is a challenge in creating a policy that will work across different formats and genres of archival materials, so this article offers some suggestions for how to think about these parameters according to US copyright law and calls for a committee of experts to work out a model policy that could serve remote users of archival collections even after the COVID-19 crisis has passed.

scholarly journals Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model

2020 ◽  
Vol 12 (12) ◽  
pp. 7454-7466
Author(s):  
Zhaoyong Zhang ◽  
Lu Zhang ◽  
Airu Zhu ◽  
Yanqun Wang ◽  
Wenda Guan ◽  
...  
Keyword(s):  
Animal Model ◽  
Narrative Review ◽  
The Novel ◽  
Novel Coronavirus
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