scholarly journals THE INFLUENCE OF CHRONIC DISEASES ON THE MANIFESTATION OF COVID-19 INFECTION

2021 ◽  
pp. 126-132
Author(s):  
S. O. Yastremska ◽  
O. M. Krekhovska-Lepiavko ◽  
B. A. Lokay ◽  
O. V. Bushtynska ◽  
S. V. Danchak
Keyword(s):  
Chronic Diseases ◽  
Case Fatality ◽  
The Novel ◽  
Fatality Rate ◽  
The World ◽  
Control And Prevention ◽  
The Usa ◽  
Life Threatening ◽  
One Year ◽  
Novel Coronavirus

Summary. The first known case of infection from the novel coronavirus was recorded almost one year ago, in China’s Hubei province. The city of Wuhan was infamous the world over as the original virus epicenter, seeing more than half of China’s reported cases and deaths. The outbreak of COVID-19 virus, as sickened more than 14.7 million people. At least 610.200 people have died. The aim of the study – to analyze and systematize the literature data about the influence of chronic diseases on the manifestation of COVID-19 infection. Materials and Methods. The study uses publications of the world scientific literature on COVID-19 infection, in particular the causes and mechanisms of its development, treatment, complications and its consequences as well as the influence of different chronic disorders on the course of COVID-19. Results. A sample of patients hospitalized with COVID-19 across 14 states of the USA in March was analyzed by The Centers for Disease Control and Prevention. It was found that many (89 %) had underlying health problem and 94 % of patients were at the age 65 and older. The case fatality rate for those under age 60 was 1.4 percent. For those over age 60, the fatality rate jumps to 4.5 percent. The older the population, the higher the fatality rate. For those 80 and over, Covid-19 appears to have a 13.4 percent fatality rate. Moreover, it was recognized, that older adults don't present in a typical way of the course of different disorders, and we're seeing that with Covid-19 as well. Conclusions. Chronic diseases and conditions are on the rise worldwide. COVID-19 became the most challenging pandemic influencing all countries worldwide. Chronic diseases are suggested to be one of the main causes of different life-threatening complications of COVID-19 infection and one of the main factors of poor prognosis for the patients.

scholarly journals 2019 Novel Coronavirus (COVID-19) pneumonia: an unusual lung ultrasound presentation.

2020 ◽  
Author(s):  
Letizia Consoli ◽  
Vittorio Bendotti ◽  
Sara Cicchinelli ◽  
Federico Gaioni ◽  
Paola Prandolini ◽  
...  
Keyword(s):  
Case Fatality Rate ◽  
Lung Ultrasound ◽  
Case Fatality ◽  
Ground Glass Opacity ◽  
Public Health Emergency ◽  
Fatality Rate ◽  
Chest Computed Tomography ◽  
Ultrasound Findings ◽  
The World ◽  
Novel Coronavirus

Abstract In December 2019, a novel coronavirus (SARS-Cov-2) was first reported in Wuhan, China, and rapidly spread around the world, leading to an international emerging public health emergency. As reported from Chinese experiences, approximately 20% of patients had a severe course, requiring intensive care, with an overall case fatality rate of 2.3%. In diagnosis, chest computed tomography most commonly showed ground-glass opacity with or without consolidative patterns.Herein we report a case of a patient affected by COVID-19 pneumonia referred in the emergency department of our institution on 4 April 2020 with peculiar lung ultrasound findings.

scholarly journals Brief Report of Guidelines and Protocols for the Management of COVID-19

2020 ◽  
Vol 3 (2) ◽  
pp. 124-133
Author(s):  
Fabricia Oliveira Oliveira ◽  
Larissa Moraes dos Santos Fonseca ◽  
Roberto Badaró ◽  
Bruna Aparecida Souza Machado
Keyword(s):  
Management Strategies ◽  
Virus Transmission ◽  
The Novel ◽  
Data Flows ◽  
The World ◽  
Control And Prevention ◽  
Novel Coronavirus ◽  
Guidelines And Recommendations ◽  
The Impact ◽  
Coordinate Data

In less than a year, the novel coronavirus rapidly changed the world scenario. To dealing with the fast spread of the disease, health associations coordinate data flows and issue guidelines to better mitigate the impact of the threat. Also, scientific groups around the world are working to ensure that all information about the mechanisms of the virus, transmission, and disease clinics is updated as the disease progresses. The objective of this study was to present the guidelines and recommendations for preventing, management strategies, clarifications about pandemics disinformation, and diagnosing COVID-19 infection in human specimens adopted from the main health centers and institutions in the world, such as WHO and Centers for Disease Control and Prevention (CDC). It is important to highlight that the rapid and effective enforcement of existing international and national action plans, as well as parallel review and improvisation, is facilitating the affected countries to contain transmission and possibly delay the peak of outbreak and mortality.

scholarly journals Nonlinear Markov Chain Modelling of the Novel Coronavirus (Covid-19) Pandemic

2020 ◽  
Author(s):  
Muammer Catak ◽  
Necati Duran
Keyword(s):  
Markov Chain ◽  
Markov Chains ◽  
Markov Chain Model ◽  
Chain Model ◽  
The Novel ◽  
The World ◽  
The Usa ◽  
Novel Coronavirus ◽  
Almost All ◽  
Markov Chain Modelling

Almost all countries around the world are struggling against the novel coronavirus (Covid-19) pandemic. In this paper, a nonlinear Markov chains model is proposed in order to analyse and to understand the behaviour of the Covid-19 pandemic. The data from China was used to build up the presented model. Thereafter, the nonlinear Markov chain model is employed to estimate the daily new Covid-19 cases in some countries including Italy, Spain, France, UK, the USA, Germany, Turkey, and Kuwait. In addition, the correlation between the daily new Covid-19 cases and the daily number of deaths is examined.

COVID-19: Socio-Economic Consequences on the Hospitality Industry in Malaysia

2021 ◽  
Vol 12 (1) ◽  
pp. 52-52
Author(s):  
Nur Hidayah Che Ahmat ◽  
Syafiqah Rahamat ◽  
Susan Wohlsdorf Arendt
Keyword(s):  
Public Health ◽  
Hospitality Industry ◽  
Economic Consequences ◽  
World Health ◽  
The Novel ◽  
Virus Spread ◽  
The World ◽  
Control And Prevention ◽  
Novel Coronavirus ◽  
Health Organization

The novel Coronavirus disease (COVID-19) first appeared in December 2019 in Wuhan, Hubei Province China before emerging in neighbouring countries in early 2020. The World Health Organization (WHO) declared COVID-19 a pandemic when the spreading of the virus started accelerating in many parts of the world and killing thousands of people. As of 22nd May 2021, there were more than 166 million confirmed cases with more than 147 million recovered and nearly 3.5 million deaths (Worldometers, n.d.). According to the WHO (2020) and Centers for Disease Control and Prevention (2020), the virus easily spreads through coughing and sneezing. Therefore, many countries implemented social distancing between individuals and various other restriction orders or recommendations (e.g., stay-at-home policies, closure of non-essential businesses) to help curb virus spread. How governments in each country reacted to control the spread of the virus appeared crucial to mitigate public health and economic impacts. Keywords: Foodservice, Hospitality, Hotel, Malaysia, Pandemic

scholarly journals Inferring True COVID19 Infection Rates From Deaths

2020 ◽  
Vol 3 ◽  
Author(s):  
Ian McCulloh ◽  
Kevin Kiernan ◽  
Trevor Kent
Keyword(s):  
Monte Carlo ◽  
The Novel ◽  
Infection Rates ◽  
Time To Death ◽  
Global Pandemic ◽  
Asymptomatic Patients ◽  
Co Morbidity ◽  
The World ◽  
Life Threatening ◽  
Novel Coronavirus

The novel coronavirus, SARS-CoV-2, commonly known as COVID19 has become a global pandemic in early 2020. The world has mounted a global social distancing intervention on a scale thought unimaginable prior to this outbreak; however, the economic impact and sustainability limits of this policy create significant challenges for government leaders around the world. Understanding the future spread and growth of COVID19 is further complicated by data quality issues due to high numbers of asymptomatic patients who may transmit the disease yet show no symptoms; lack of testing resources; failure of recovered patients to be counted; delays in reporting hospitalizations and deaths; and the co-morbidity of other life-threatening illnesses. We propose a Monte Carlo method for inferring true case counts from observed deaths using clinical estimates of Infection Fatality Ratios and Time to Death. Findings indicate that current COVID19 confirmed positive counts represent a small fraction of actual cases, and that even relatively effective surveillance regimes fail to identify all infectious individuals. We further demonstrate that the miscount also distorts officials' ability to discern the peak of an epidemic, confounding efforts to assess the efficacy of various interventions.

scholarly journals Egypt's COVID-19 Recent Happenings and Perspectives: A Mini-Review

2021 ◽  
Vol 9 ◽  
Author(s):  
AbdulRahman A. Saied ◽  
Asmaa A. Metwally ◽  
Norah Abdullah Bazekh Madkhali ◽  
Shafiul Haque ◽  
Kuldeep Dhama
Keyword(s):  
Case Fatality Rate ◽  
Case Fatality ◽  
Animal Origin ◽  
Fatality Rate ◽  
Health Concerns ◽  
The World ◽  
The Usa ◽  
Egyptian Government ◽  
Low Prevalence ◽  
And Control

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected countries across the world. While the zoonotic aspects of SARS-CoV-2 are still under investigation, bats and pangolins are currently cited as the animal origin of the virus. Several types of vaccines against COVID-19 have been developed and are being used in vaccination drives across the world. A number of countries are experiencing second and third waves of the pandemic, which have claimed nearly four million lives out of the 180 million people infected globally as of June 2021. The emerging SARS-CoV-2 variants and mutants are posing high public health concerns owing to their rapid transmissibility, higher severity, and in some cases, ability to infect vaccinated people (vaccine breakthrough). Here in this mini-review, we specifically looked at the efforts and actions of the Egyptian government to slow down and control the spread of COVID-19. We also review the COVID-19 statistics in Egypt and the possible reasons behind the low prevalence and high case fatality rate (CFR%), comparing Egypt COVID-19 statistics with China (the epicenter of COVID-19 pandemic) and the USA, Brazil, India, Italy, and France (the first countries in which the numbers of patients infected with COVID-19). Additionally, we have summarized the SARS-CoV-2 variants, vaccines used in Egypt, and the use of medicinal plants as preventive and curative options.

scholarly journals COVID-19 and Thrombosis Predisposition

2020 ◽  
Vol 5 (3) ◽  
pp. 86-90
Author(s):  
Renata Gerculy ◽  
Camelia Libenciuc ◽  
Nora Rat ◽  
Monica Chitu ◽  
Imre Benedek
Keyword(s):  
Infectious Disease ◽  
Current Knowledge ◽  
The Novel ◽  
Coagulation Disorders ◽  
Healthy Individuals ◽  
The World ◽  
Life Threatening ◽  
Thrombotic Complications ◽  
Disease Spreading ◽  
Novel Coronavirus

AbstractThe novel coronavirus disease first appeared in Wuhan (China) is an infectious disease spreading throughout the world, causing life-threatening conditions in vulnerable or even healthy individuals. The great impact of this virus on healthcare urges physicians to investigate all aspects of the disease in order to overcome its complications. A particularly investigated aspect of the SARS-CoV-2 infection is represented by the coagulation disorders among infected and critically ill patients. Several studies observed modified blood coagulation parameters such as D-dimers, fibrinogen, and coagulation times. Moreover, the severe thrombotic complications, mainly pulmonary embolism, could be responsible for the high mortality and poorer outcomes of COVID-19 infected patients. The aim of this article is to present the current knowledge related to thrombosis predisposition in patients infected with the new coronavirus.

scholarly journals A Method to Model Outbreaks of New Infectious Diseases with Pandemic Potential such as COVID-19

2020 ◽  
Author(s):  
Willem G. Odendaal
Keyword(s):  
Infectious Disease ◽  
Monte Carlo ◽  
Financial Markets ◽  
Infectious Agent ◽  
The Novel ◽  
Acceptable Accuracy ◽  
The World ◽  
Travel Restrictions ◽  
The Usa ◽  
Novel Coronavirus

AbstractThe emergence of the novel coronavirus (a.k.a. COVID-19, SARS-CoV-2) out of Wuhan, Hubei Province, China caught the world by surprise. As the outbreak began to spread outside of China, too little was known about the virus to model its transmission with any acceptable accuracy. World governments responded to rampant misinformation about the virus leading to collateral disasters, such as plunging financial markets, that could have been avoided if better models of the outbreak had been available. This is an engineering approach to model the spread of a new infectious disease from sparse data when little is known about the infectious agent itself. The paper is not so much about the model itself - because there are many good scientific approaches to model an epidemic - as it is about crunching numbers when there are barely any numbers to crunch. The coronavirus outbreak in USA is used to illustrate the implementation of this modeling approach. A Monte Carlo approach is implemented by using incubation period and testing efficiency as variables. Among others it is demonstrated that imposing early travel restrictions from infected countries slowed down the outbreak in the USA by about 26 days.

scholarly journals Unique Features and Intensity of COVID-19 Spread in Large Economies

2020 ◽  
Vol 27 (6) ◽  
pp. 86-104
Author(s):  
V. M. Chetverikov
Keyword(s):  
Case Fatality ◽  
Fatality Rate ◽  
Daily Growth ◽  
Health Security ◽  
Emerging Trends ◽  
The World ◽  
The Face ◽  
The Republic ◽  
One Year ◽  
Restrictive Measures

The article focuses on determining the unique features and intensity of Covid-19 spread in large economies, using mathematical and statistical tools. According to international statistics and using the example of 24 countries, each producing more than 1% of the world GDP at least one year between 1980 and 2019, the author carried out a preliminary analysis of geographical distribution and spread of the viral pandemic, that in 2020 overtook almost the whole world. It is suggested the data for these countries be grouped into three types of scenarios, dividing them into several options. The work uses time series for three indicators, calculated per 1 million of the country’s population. Two of these indicators reflect, respectively, the levels of infection and incidence of coronavirus cases, and the third - daily growth of COVID-19 cases. Such a system of indicators allows, according to the author, to adequately determine emerging trends and is convenient for comparing the unique features and intensity pandemic spread in different countries. The article presents a hypothesis about the possible reasons for the synchronization of trends for different countries in which the same type of scenario came true. It is demonstrated that the often-used case-fatality rate is not very informative in conditions when the pandemic is far from ending. A more illustrative indicator of healthcare system mobilization capacity as a whole in the face of global challenges is the infection fatality rate per 1 million of the country’s population. The ranking of all 24 countries by this indicator significantly differs from the Global Health Security Index ranking, published in 2019. After the conclusion, in the appendix to the article, the author provides illustrations in the form of graphs tracking the pandemic spread in the countries under review, as well as brief information on particular aspects of the Republic of Korea response to managing and combatting the most dangerous infection, which is different from both temporary but harsh restrictive measures for the population in the PRC and relatively mild measures implemented in many countries of the world.

scholarly journals Adjunctive Nutraceutical Therapies for COVID-19

2021 ◽  
Vol 22 (4) ◽  
pp. 1963
Author(s):  
Lalita Subedi ◽  
Stephanie Tchen ◽  
Bhakta Prasad Gaire ◽  
Bingren Hu ◽  
Kurt Hu
Keyword(s):  
Respiratory Virus ◽  
Viral Infections ◽  
World Health ◽  
The Novel ◽  
Appropriate Use ◽  
The World ◽  
Life Threatening ◽  
Novel Coronavirus ◽  
Health Organization ◽  
And Function

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/COVID-19), is a worldwide pandemic, as declared by the World Health Organization (WHO). It is a respiratory virus that infects people of all ages. Although it may present with mild to no symptoms in most patients, those who are older, immunocompromised, or with multiple comorbidities may present with severe and life-threatening infections. Throughout history, nutraceuticals, such as a variety of phytochemicals from medicinal plants and dietary supplements, have been used as adjunct therapies for many disease conditions, including viral infections. Appropriate use of these adjunct therapies with antiviral proprieties may be beneficial in the treatment and/or prophylaxis of COVID-19. In this review, we provide a comprehensive summary of nutraceuticals, such as vitamins C, D, E, zinc, melatonin, and other phytochemicals and function foods. These nutraceuticals may have potential therapeutic efficacies in fighting the threat of the SARS-CoV-2/COVID-19 pandemic.

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