scholarly journals Characterization of Flavonoid and Naphthopyranone Derivatives from Eriocaulon ligulatum using Liquid Chromatography Tandem Mass Spectrometry

2009 ◽  
Vol 4 (12) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Lourdes Campaner dos Santos ◽  
Marcelo Aparecido da Silva ◽  
Clenilson Martins Rodrigues ◽  
Virginia Carbone ◽  
Assunta Napolitano ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Methanol Extract ◽  
Ion Trap ◽  
Ion Trap Mass Spectrometry ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Fragmentation Patterns

Liquid chromatography-electrospray ionization multistage ion trap mass spectrometry (LC-ESI-IT-MSn) was used to analyze the secondary metabolites in the methanol extract of the capitulae of Eriocaulon ligulatum. The major components were mono-and diglycosides of flavonoids and naphthopyranones. Eleven compounds, including four new flavonol glycosides, were identified based on their fragmentation patterns in MS experiments and on NMR analysis of the isolated compounds. The described data may contribute to a better understanding of the taxonomic classification of the Eriocaulaceae family.

Application of liquid chromatography/ion trap mass spectrometry to the characterization of the related substances of clarithromycin

2006 ◽  
Vol 20 (20) ◽  
pp. 3101-3110 ◽  
Author(s):  
Stefanie Leonard ◽  
Monica Ferraro ◽  
Erwin Adams ◽  
Jos Hoogmartens ◽  
Ann Van Schepdael
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Ion Trap ◽  
Ion Trap Mass Spectrometry ◽  
Related Substances

scholarly journals LC-MS/MS Method Development for the Discovery and Identification of Amphidinols Produced by Amphidinium

Marine Drugs ◽  
2020 ◽  
Vol 18 (10) ◽  
pp. 497
Author(s):  
Marvin Wellkamp ◽  
Francisco García-Camacho ◽  
Lorena M. Durán-Riveroll ◽  
Jan Tebben ◽  
Urban Tillmann ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Method Development ◽  
Neutral Loss ◽  
Tandem Mass ◽  
Reaction Monitoring ◽  
Fish Kills ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Fragmentation Patterns

Amphidinols are polyketides produced by dinoflagellates suspected of causing fish kills. Here, we demonstrate a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the identification and quantification of amphidinols (AM). Novel AM were detected by neutral loss (NL) scan and then quantified together with known AM by selection reaction monitoring (SRM). With the new method, AM were detected in four of eight analyzed strains with a maximum of 3680 fg toxin content per cell. In total, sixteen novel AM were detected by NL scan and characterized via their fragmentation patterns. Of these, two substances are glycosylated forms. This is the first detection of glycosylated AM.

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