Structure and Absolute Configuration of a Diterpenoid from Castanea mollissima
2010 ◽
Vol 5
(1)
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pp. 1934578X1000500
Keyword(s):
2D Nmr
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From the nuts of Castanea mollissima Blume, a new kauranoid diterpene glycoside, named mollioside (1), was isolated. Its structure was established as (4R, 5S, 6R, 8R, 9S, 10S, 13R, 16R) 17-O-β-D-glucopyranoside, ent-6,7-epoxy-6α-hydroxyl-6,7-secokaur-19-oic acid, 6, 19-lactone-16β, 17-diol on the basis of HR-FAB-MS, 1D, 2D-NMR and CD spectral analysis. The aglycone (1a, named mollissin), also as a new compound, was obtained after enzymatic hydrolysis of 1. Both compounds exhibited significant growth inhibitory activity on HeLa tumor cells, but no activity on A375-S2.
1984 ◽
pp. 215
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Keyword(s):
1984 ◽
Vol 99
(4)
◽
pp. 1227-1234
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Keyword(s):
2013 ◽
Vol 8
(3)
◽
pp. 1934578X1300800
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