scholarly journals A comparison of the direct medical costs for individuals with or without basal or squamous cell skin cancer: A study from Australia

2016 ◽  
Vol 4 ◽  
pp. 205031211664603 ◽  
Author(s):  
David Rowell ◽  
Louisa G Gordon ◽  
Catherine M Olsen ◽  
David C Whiteman
Keyword(s):  
Skin Cancer ◽  
Squamous Cell ◽  
Medical Costs ◽  
Squamous Cell Carcinomas ◽  
Health Conditions ◽  
Health Insurance Data ◽  
Direct Medical Costs ◽  
History Of ◽  
Insurance Data ◽  
Health Service Costs

Objectives: The composition of the medical costs incurred by people treated for basal cell and squamous cell carcinomas (hereafter keratinocyte cancers) is not adequately understood. We sought to compare the medical costs of individuals with or without keratinocyte cancers. Methods: We used national health insurance data to analyze the direct medical costs of 2000 cases and 2000 controls nested within the QSkin prospective cohort study (n = 43,794) conducted in Australia. We reconstructed the medical history of patients using medical and pharmaceutical item codes and then compared the health service costs of individuals treated for keratinocyte cancers with those not treated for keratinocyte cancers. Results: Individuals treated for keratinocyte cancers consumed on average AUD$1320 per annum more in medical services than those without keratinocyte cancers. Only 23.2% of costs were attributed to the explicit treatment of keratinocyte cancers. The principal drivers of the residual costs were medical attendances, surgical procedures on the skin, and histopathology services. We found significant positive associations between history of treatment for keratinocyte cancers with treatments for other health conditions, including melanoma, cardiovascular disease, lipidemia, osteoporosis, rheumatoid arthritis, colorectal cancer, prostate cancer, and tuberculosis. Conclusion: Individuals treated for keratinocyte cancers have substantially higher medical costs overall than individuals without keratinocyte cancers. The direct costs of skin cancer excision account for only one-fifth of this difference.

scholarly journals Epidemiology of basal cell carcinomas and squamous cell carcinomas in a Department of Dermatology: a 5 year review

2012 ◽  
Vol 87 (2) ◽  
pp. 212-219 ◽  
Author(s):  
Pedro Andrade ◽  
Maria Manuel Brites ◽  
Ricardo Vieira ◽  
Angelina Mariano ◽  
José Pedro Reis ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Squamous Cell ◽  
Basal Cell ◽  
Skin Neoplasms ◽  
Squamous Cell Carcinomas ◽  
Exposed Skin ◽  
Non Melanoma Skin Cancer ◽  
Basal Cell Carcinomas ◽  
Malignant Skin ◽  
Melanoma Skin

BACKGROUND: Non-melanoma skin cancer, a common designation for both basal cell carcinomas and squamous cell carcinomas, is the most frequent malignant skin neoplasm. OBJECTIVE: Epidemiologic characterization of the population with Non-melanoma skin cancer. METHODS: Retrospective analysis of all patients diagnosed with Non-melanoma skin cancer based on histopathologic analysis of all incisional or excisional skin biopsies performed between 2004 and 2008 in a Department of Dermatology. RESULTS: A total of 3075 Non-melanoma skin cancers were identified, representing 88% of all malignant skin neoplasms (n=3493) diagnosed in the same period. Of those, 68,3% were basal cell carcinomas. Most Non-melanoma skin cancer patients were female and over 60 years old. Of all Non-melanoma skin cancer, 81,7% (n=1443) were located in sun-exposed skin, and represented 95,1% of malignant skin neoplasms in sun-exposed skin. Non-melanoma skin cancer was the most frequent malignant skin neoplasm in most topographic locations, except for abdomen and pelvis - over 95% of all malignant skin neoplasms in the face, neck and scalp were Non-melanoma skin cancer. Basal cell carcinomas were clearly predominant in all locations, except in upper and lower limbs, lower lip and genitals, where squamous cell carcinomas represented respectively 77,7%, 77,4%, 94,7% and 95,3% of the Non-melanoma skin cancers. CONCLUSION: Being the most common skin cancer, Non-melanoma skin cancer should be under constant surveillance, in order to monitor its epidemiologic dynamics, the efficiency of preventive measures and the adaptation of the healthcare resources.

The Majority of Cutaneous Squamous Cell Carcinomas Arise in Actinic Keratoses

2002 ◽  
Vol 6 (3) ◽  
pp. 207-209 ◽  
Author(s):  
D. Czarnecki ◽  
C. J. Meehan ◽  
F. Bruce ◽  
G. Culjak
Keyword(s):  
Family History ◽  
Squamous Cell ◽  
Retrospective Studies ◽  
Prognostic Significance ◽  
Squamous Cell Carcinomas ◽  
Histological Features ◽  
Actinic Keratoses ◽  
Skin Cancers ◽  
History Of ◽  
A Prospective Study

Background: Retrospective studies have given conflicting results with respect to how many cutaneous squamous cell carcinomas (SCCs) arise in actinic keratoses (AK). Objective: This study was conducted to determine what percentage of SCCs arise in AKs and to obtain more information about two histological features of SCCs, namely, thickness and ulceration. Methods: A prospective study was done of all SCCs treated by the authors during one calendar year. Results: Two hundred eight patients with SCC were entered into the study. An AK was contiguous with an SCC in 72% of the cases. This was taken as evidence that the SCC arose in the AK. Men presented with thicker and more ulcerated SCCs than women, but these were not statistically significant: p = 0.06 for thickness and p = 0.07 for ulceration. Ulcerated SCCs were more likely to arise on the head and neck (p = 0.02), on patients who had multiple skin cancers ( p = 0.005), and on patients who had a family history of skin cancer ( p = 0.03). Conclusion: Actinic keratoses need to be removed before they turn into SCCs. The prognostic significance of ulceration of cutaneous SCCs needs to be determined.

scholarly journals The impact of extra-musculoskeletal manifestations on disease activity, functional status, and treatment patterns in patients with axial spondyloarthritis: results from a nationwide population-based study

2020 ◽  
Vol 12 ◽  
pp. 1759720X2097261
Author(s):  
Imke Redeker ◽  
Britta Siegmund ◽  
Kamran Ghoreschi ◽  
Uwe Pleyer ◽  
Johanna Callhoff ◽  
...  
Keyword(s):  
Disease Activity ◽  
Functional Status ◽  
Axial Spondyloarthritis ◽  
Population Based ◽  
Treatment Patterns ◽  
Health Insurance Data ◽  
History Of ◽  
Musculoskeletal Manifestations ◽  
Disease Modifying ◽  
Insurance Data

Objective: The aim of this study was to investigate the association of extra-musculoskeletal manifestations (EMMs) with disease activity, functional status, and treatment patterns in a large population-based cohort of patients with axial spondyloarthritis (axSpA). Methods: A stratified random sample of patients with axSpA, drawn from health insurance data, received a survey on disease-related characteristics including history (ever presence) of the following EMMs: inflammatory bowel disease (IBD), psoriasis (PSO), and anterior uveitis (AU). Survey data were linked to health insurance data, gathering additional information on current occurrence (within one year) of EMMs and drug prescriptions. Separate multivariable linear regression models were calculated to determine the association of EMMs with disease activity (Bath Ankylosing Spondylitis Disease Activity Index), and functional status (Bath Ankylosing Spondylitis Functional Index) after adjustment for relevant parameters, including treatment. Results: A total of 1729 patients with axSpA were included in the analyses (response: 47%; mean age: 56 years; 46% female) of whom 6% (9%) had current (ever) IBD, 10% (15%) had current (ever) PSO, and 9% (27%) had current (ever) AU. Ever presence of IBD and history of PSO were significantly associated with higher level of disease activity. Ever presence of PSO was also associated with higher level of functional impairment, whereas current AU was significantly associated with lower disease activity. Patients with current IBD or PSO received more frequently biological and conventional synthetic disease-modifying anti-rheumatic drugs as well as systemic steroids. AU was associated with a higher use of conventional synthetic disease-modifying anti-rheumatic drugs only. Conclusion: Disease activity is higher in patients with axSpA with history of IBD or history of PSO. Functional impairment is also higher in patients with axSpA with history of PSO. The presence of different EMMs was associated with different treatment patterns in axSpA.

Skin Cancer Knowledge and Preventive Behaviors among Patients with a Recent History of Cutaneous Squamous Cell Carcinoma

Dermatology ◽  
2008 ◽  
Vol 217 (1) ◽  
pp. 74-80 ◽  
Author(s):  
Cristina Renzi ◽  
Simona Mastroeni ◽  
Thomas J. Mannooranparampil ◽  
Francesca Passarelli ◽  
Alessio Caggiati ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Recent History ◽  
Cancer Knowledge ◽  
Preventive Behaviors ◽  
History Of

Rapidly Growing Squamous Cell Carcinoma

1999 ◽  
Vol 3 (4) ◽  
pp. 193-197 ◽  
Author(s):  
Elizabeth M. Billingsley ◽  
Nicole Davis ◽  
Klaus F. Helm
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Rapid Growth ◽  
Average Duration ◽  
Squamous Cell Carcinomas ◽  
Viral Etiology ◽  
Immunosuppressed Patients ◽  
History Of ◽  
Average Size

Background: Squamous cell carcinoma (SCC) may present with a history of rapid growth. Although multiple subtypes have been described regarding histologic characteristics and etiology, the subset of rapidly growing squamous cell carcinomas (RGSCC) has not been described. Objective: To evaluate and describe the clinical and histologic characteristics of squamous cell carcinomas that grow rapidly. Methods: Recorded clinical data and biopsies of 26 lesions with a history of rapid growth and histologically diagnosed as SCC were reviewed. Results: Rapidly growing SCC occurred most commonly on the head and neck, followed by hands and extremities, and had an average duration of 7 weeks before diagnosis. The average size of the lesions was 1.29 cm and nearly 20% occurred in immunosuppressed patients. Conclusions: Some SCCs may grow rapidly. The reason for the rapid growth is not clear and several hypotheses are discussed including immunosuppression and viral etiology. These lesions should be treated aggressively as their behaviour and prognosis are not yet well described.

scholarly journals The Evolution of Staging of Cutaneous Squamous Cell Carcinomas: A Structured Review

2017 ◽  
Vol 8 (2) ◽  
pp. 57-63 ◽  
Author(s):  
Mina N Le ◽  
Erica Lee ◽  
Bhuvanesh Singh
Keyword(s):  
Squamous Cell ◽  
Cancer Staging ◽  
Squamous Cell Carcinomas ◽  
Future Directions ◽  
Skin Cancers ◽  
Staging Systems ◽  
History Of ◽  
The Common ◽  
Ajcc Staging ◽  
Melanoma Skin

ABSTRACT Among non-melanoma skin cancers, cutaneous squamous cell carcinoma entails the highest morbidity and mortality, and yet there is little guidance on how to identify the subset of cutaneous squamous cell carcinomas that behave aggressively. The staging of non-melanoma skin cancers is meant to provide this guidance, by dividing patients into groups for which survival differs between groups, is similar within each group, and consistently decreases with each increasing stage group. In the present review, we explore the history of how the staging of non-melanoma skin cancers, focusing on cutaneous squamous cell carcinomas, has evolved over time. We describe the common criticisms leveled at the American Joint Committee on Cancer (AJCC) staging rubric. We discuss alternative staging systems that have recently been proposed, and how they have stood up to validation. Finally, we preview the AJCC staging changes that will go into effect next year and lay out some future directions for the improvement of skin cancer staging. How to cite this article Le MN, Lee E, Singh B. The Evolution of Staging of Cutaneous Squamous Cell Carcinomas: A Structured Review. Int J Head Neck Surg 2017;8(2):57-63.

scholarly journals Squamous Cell Carcinoma (SCC) and Chronic Radiation Dermatitis Associated with Childhood Ionizing Radiation Exposure: Case Report with Review of the Literature

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Kai-Lou C. Yue ◽  
Isabelle Lombardi ◽  
Lohit Sodagum ◽  
Dennis Porto
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Ionizing Radiation ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Radiation Dermatitis ◽  
Chronic Radiation ◽  
History Of ◽  
High Index Of Suspicion ◽  
Ionizing Radiation Exposure

Introduction: Squamous cell carcinoma (SCC) is one of the most common types of skin cancer in Caucasians, but the role played by ionizing radiation (IR) exposure in its etiology is unclear. Case Presentation: This study presents a patient with SCC, actinic keratoses, and radiation dermatitis of the feet with a distant history of IR exposure from a shoe-fitting fluoroscope. It is likely the fluoroscope’s IR contributed to the etiology of these manifestations. Conclusions: Patients with a history of repeated IR exposure, particularly from older, unregulated sources such as a shoe-fitting fluoroscope, should be monitored with a high index of suspicion for skin cancer and other related problems.

scholarly journals High-Grade Squamous Intraepithelial Lesion of the Gastroesophageal Junction Secondary to High-Risk Human Papillomavirus

2019 ◽  
Vol 152 (3) ◽  
pp. 359-364
Author(s):  
Edward B Stelow ◽  
Erik A Dill ◽  
Jonathan J Davick ◽  
Michael B McCabe ◽  
Vanessa M Shami
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Squamous Cell ◽  
Gastroesophageal Junction ◽  
Squamous Cell Carcinomas ◽  
High Grade ◽  
Squamous Intraepithelial Lesion ◽  
History Of ◽  
Intraepithelial Lesion ◽  
High Risk Hpv

ABSTRACT Objectives Although the role of human papillomavirus (HPV) in the development of some carcinomas (eg, anogenital and oropharyngeal squamous cell carcinomas) is nondebatable, there is still significant controversy regarding the relationship of HPV and esophageal squamous cell carcinomas (SCCs). Methods All cases were sampled at or near the gastroesophageal junctions in patients with reflux and/or known Barrett esophagus and appear to have been initially sampled “incidentally.” Patients were all men, aged 56 to 80 years. None had a known history of other HPV-related disease. Results We present four cases of high-grade squamous intraepithelial lesion of the gastroesophageal junction secondary to high-risk HPV that have identical histologic features to similar lesions of the anogenital tract. Conclusions Whether such lesions are at risk for developing into invasive SCC remains unclear.

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