A natural solution for obesity: Bioactives for the prevention and treatment of weight gain. A review

2014 ◽  
Vol 18 (2) ◽  
pp. 49-65 ◽  
Author(s):  
Cristina Torres-Fuentes ◽  
Harriët Schellekens ◽  
Timothy G. Dinan ◽  
John F. Cryan
2021 ◽  
Vol 77 (09) ◽  
pp. 6571-2021
Author(s):  
KAROLINA FABIA ◽  
DARIUSZ WOLSKI ◽  
MAREK BIEŃKO ◽  
RADOSŁAW P. RADZKI ◽  
SYLWIA SZYMAŃCZYK

In industrial poultry production, especially in broiler chickens, coccidiosis, caused by Eimeria protozoa parasites in the digestive tract, continues to be a serious health and economic problem. In economic terms, the losses are mainly caused by the costs of prevention and treatment, as well as the reduced weight gain and reduced condition of the birds. Currently, the prophylactic program of this disease unit is mainly based on the use of chemotherapeutics. Another way to control coccidiosis is active immunoprophylaxis, based on the vaccination of chickens for fattening, and passive immunoprophylaxis, based on vaccination of the parent flock. An alternative, effective way to reduce the negative effects of protozoan infestation by Eimeria may be the use of herbs and their extracts, pre- and probiotics and betaine.


Author(s):  
E.S. Krasnikova ◽  
◽  
R.V. Radionov ◽  
A.V. Krasnikov ◽  
◽  
...  

The scientific article is devoted to evaluation of the original author's composition effectiveness for prevention and treatment of dyspepsia in newborn calves from BLV-infected cows. It is shown that use of the composition for prophylactic purposes reduces possibility of dyspepsia development in 20.82 % calves, and for therapeutic purposes reduces the treatment duration of dyspeptic manifestations in 28.35 % of newborn calves up to 3 days and increases the safety of livestock up to 100%. The obtained data are supported by the results of morphological and biochemical analyses of calves' blood, microbiological studies of the intestinal contents, indicating a rapid recovery of the animal homeostasis with opportune use of the composition for preventive or therapeutic purposes. It was found that use of the author's development allows us to keep the weight gain in calves from immunocompromised mothers at the level of intact animals.


PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e12009
Author(s):  
Mevra Aydin Cil ◽  
Atena Ghosi Ghareaghaji ◽  
Yasin Bayir ◽  
Zehra Buyuktuncer ◽  
Halit Tanju Besler

Backround This study aimed to determine the effects of LC n-3 PUFA supplementation on the prevention and treatment of obesity and obesity-related diseases, and to compare the efficiency of different LC n-3 PUFA sources via biochemical and genetic mechanisms in rats. Methods Male Wistar rats were randomized into four study groups, and fed with a standard diet, High Fat Diet (HFD), HFD+%2.5 Fish Oil (FO-HFD) or HFD+%2.5 Krill Oil (KO-HFD) for eight weeks. Food consumption, weight gain, serum glucose, insulin, ghrelin and leptin concentrations, lipid profile, liver fatty acid composition, and FADS1 and FADS2 mRNA gene expression levels were measured. Results Weight gain in each HFD group was significantly higher than control group (p < 0.001), without any differences among them (p < 0.05). LC n-3 PUFAs modified lipid profile, but not glucose tolerance. Serum leptin levels were significantly higher in HFD groups than in the control group, however, no difference in serum ghrelin levels was observed among the groups. Liver n-3 fatty acid desaturation activity was higher (p = 0.74), and liver total lipid content was lower (p = 0.86) in KO-HFD compared to FO-HFD. FADS1 gene expression was highest in the HFD group (p < 0.001) while FADS2 gene expression was highest in the FO-HFD group (p < 0.001). Conclusion LC n-3 PUFAs, especially krill oil, had moderate effects on lipid profile, but limited effects on obesity related parameters, suggesting different effects of different sources on gene expression levels. Further randomized controlled trials are needed to determine the efficacy of different LC n-3 PUFA sources in the prevention and treatment of obesity in humans.


2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Varuni Asanka de Silva ◽  
Chathurie Suraweera ◽  
Suhashini S. Ratnatunga ◽  
Madhubashinee Dayabandara ◽  
Nimali Wanniarachchi ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Yoram Barak ◽  
Dov Aizenberg

Weight gain is one of the major drawbacks associated with the pharmacological treatment of schizophrenia. Existing strategies for the prevention and treatment of obesity amongst these patients are disappointing. Switching the current antipsychotic to another that may favorably affect weight is not yet fully established in the psychiatric literature. This meta-analysis focused on switching to aripiprazole as it has a pharmacological and clinical profile that may result in an improved weight control. Nine publications from seven countries worldwide were analyzed. These encompassed 784 schizophrenia and schizoaffective patients, 473 (60%) men and 311 (40%) women, mean age years. The major significant finding was a mean weight reduction by  kgs following the switch to aripiprazole (). Switching to an antipsychotic with a lower propensity to induce weight gain needs be explored as a strategy. Our analysis suggests aripiprazole as a candidate for such a treatment strategy.


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