Mortalin and DJ-1 coordinately regulate hematopoietic stem cell function through the control of oxidative stress
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Key Points Mitochondrial heat shock protein, mortalin, is essential for the maintenance of HSCs via the control of oxidative stress. Mortalin directly interact with DJ-1 to regulate ROS levels in the mitochondria of HSCs.
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2017 ◽
Vol 1
(26)
◽
pp. 2520-2528
◽
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