Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis
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Key Points Inactivation of Suz12 results in a rapid and marked exhaustion of the HSC pool. Lymphoid development is completely dependent on PRC2, but numerous myeloid lineages develop in the absence of PRC2.
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2017 ◽
Vol 1
(26)
◽
pp. 2520-2528
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