scholarly journals The clinical spectrum of Erdheim-Chester disease: an observational cohort study

2017 ◽  
Vol 1 (6) ◽  
pp. 357-366 ◽  
Author(s):  
Juvianee I. Estrada-Veras ◽  
Kevin J. O’Brien ◽  
Louisa C. Boyd ◽  
Rahul H. Dave ◽  
Benjamin H. Durham ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Age Of Onset ◽  
Observational Cohort Study ◽  
World Health ◽  
Key Points ◽  
The World ◽  
Observational Cohort ◽  
Health Organization ◽  
Erdheim Chester ◽  
Chester Disease

Key Points ECD varies in terms of age of onset, clinical presentation, manifestations, organ involvement, disease severity, and survival. ECD is a neoplasm and should be adopted by the field of hematology-oncology following the World Health Organization reclassification.

scholarly journals Buruli Ulcer: Review of a Neglected Skin Mycobacterial Disease

2017 ◽  
Vol 56 (4) ◽  
Author(s):  
Jeannette Guarner
Keyword(s):  
Clinical Presentation ◽  
Oral Treatment ◽  
Buruli Ulcer ◽  
Mycobacterium Ulcerans ◽  
World Health ◽  
Tissue Necrosis ◽  
Content Type ◽  
Skin Nodule ◽  
The World ◽  
Health Organization

ABSTRACTBuruli ulcer is caused byMycobacterium ulcerans. This neglected disease occurs in scattered foci around the world, with a higher concentration of cases in West Africa. The mycobacteria produce mycolactones that cause tissue necrosis. The disease presents as a painless skin nodule that ulcerates as necrosis expands. Finding acid-fast bacilli in smears or histopathology, culturing the mycobacteria, and performingM. ulceransPCR in presumptive cases confirm the diagnosis. Medical treatment with oral rifampin and intramuscular streptomycin or oral treatment with rifampin plus clarithromycin for 8 weeks is supported by the World Health Organization. This review summarizes the epidemiology, pathogenesis, clinical presentation, diagnostic tests, and advances in treatment.

scholarly journals The Incidence and Determinants of Metabolic Syndrome Amongst a Group of Migrants to Qatar: A Prospective Longitudinal Observational Cohort Study 24-Months Post-Migration

2021 ◽  
Vol 11 (1) ◽  
pp. 34
Author(s):  
Rana Moustafa Al-Adawi ◽  
Kirti Sathyananda Prabhu ◽  
Derek Stewart ◽  
Cristin Ryan ◽  
Hani Abdelaziz ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Hdl Cholesterol ◽  
Observational Cohort Study ◽  
World Health ◽  
Observational Cohort ◽  
Health Organization ◽  
Prospective Longitudinal ◽  
The Relationship ◽  
New Onset

While there is some evidence that migration to Western countries increases metabolic syndrome (MetS) risk, there is a lack of data pertaining to migration to the Middle East. This study aimed to investigate the relationship between migration and MetS incidence following 24-months of residency in Qatar and identify possible MetS determinants. Migrants to Qatar employed at Hamad Medical Corporation (the national health service) aged 18–65 years were invited to participate. Baseline and follow-up screening for MetS included HbA1c, triglycerides, HDL-cholesterol, blood pressure, and waist circumference. MetS-free migrants were rescreened 24-months post-migration, and the World Health Organization STEPwise questionnaire was administered, assessing changes in lifestyle from baseline. Of 1095 migrants contacted, 472 consented to participate, 205 of whom had normal metabolic parameters at baseline; 160 completed follow-up screening. Most participants were males (74.6%, n = 153) and Asian (81.0%, n = 166/205), and two thirds (66.3%, n = 136/205) were nurses. The incidence of new-onset MetS was 17.0% (n = 27/160, 95%CI; 11.0–23.0%), with 81.0% (n = 129/160, 95%CI; 73.8–86.0%) having at least one MetS element 24-months post-residency in Qatar. Male gender was a risk factor for MetS (adjusted odds ratio (AOR) = 3, p = 0.116), as was consuming medication that could induce MetS (AOR = 6.3, p < 0.001). There is merit in further research targeting these groups.

The Phenomenology and Epidemiology of Intermittent Explosive Disorder

2012 ◽  
Author(s):  
Ronald C. Kessler ◽  
Emil F. Coccaro ◽  
Maurizio Fava ◽  
Katie A. McLaughlin
Keyword(s):  
Age Of Onset ◽  
Epidemiological Studies ◽  
World Health ◽  
Early Age ◽  
Intermittent Explosive Disorder ◽  
National Comorbidity Survey Replication ◽  
Anger Attacks ◽  
The World ◽  
Health Organization ◽  
The U.S

Intermittent explosive disorder (IED) is characterized by recurrent episodes of impulsive, uncontrollable aggression out of proportion to the severity of provoking agents. Few epidemiological studies have been carried out on the prevalence and correlates of IED. Data are reported here from the most recent and largest of these studies: the U.S. National Comorbidity Survey Replication (NCS-R) and the World Health Organization World Mental Health (WMH) surveys. These studies show that IED is a commonly occurring disorder that typically has an early age of onset, a persistent course, and strong comorbidity with a number of other usually secondary mental disorders. This disorder is almost twice as common among men as women. It is often associated with substantial distress and impairment. However, only a minority of people with IED obtain treatment for their uncontrollable anger. This combination of features makes IED an ideal target for early detection and intervention aimed at secondary prevention of anger attacks as well as primary prevention of secondary disorders.

Rare giant cell ependymoma in an octogenarian

2006 ◽  
Vol 105 (6) ◽  
pp. 908-911 ◽  
Author(s):  
Patrick B. Cooper ◽  
Matthew Katus ◽  
Leon Moores ◽  
Dennis Geyer ◽  
James G. Smirniotopoulos ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Giant Cell ◽  
Unusual Case ◽  
Clinical Presentation ◽  
Surgical Intervention ◽  
Relevant Literature ◽  
World Health ◽  
Radiological Findings ◽  
The World ◽  
Health Organization

✓Ependymomas are glial tumors that occur most often in children. In adults, ependymomas most often appear in the spinal cord. The World Health Organization recognizes several rare ependymoma subtypes, including the giant cell ependymoma of the terminal filum. The authors describe an unusual case of a posterior fossa giant cell ependymoma in an 89-year-old man presenting with vertigo and disequilibrium. Only seven cases of this tumor have been reported in the literature to date. The authors discuss the clinical presentation, radiological findings, pathological considerations, and surgical intervention in this patient and review the relevant literature.

scholarly journals Potassium Levels in COVID Subjects: Current Observations and New Possibilities for its use in COVID Diagnosis

2021 ◽  
pp. 1-8
Author(s):  
Sriram Padmanabhan
Keyword(s):  
Clinical Presentation ◽  
Accurate Diagnosis ◽  
World Health ◽  
Detection Methods ◽  
Potassium Ions ◽  
Infected Person ◽  
Pharmacological Treatments ◽  
The World ◽  
Health Organization ◽  
Global Threat

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) causing covid infection in humans is a major global threat to healthcare and economy. According to the recent statistics of the World Health Organization (WHO), the disease has already involved all continents, with almost 117,498,522 cases with more than 2,606,626 deaths all over the globe until March 2021. It is thus, imperative to study and develop pharmacological treatments suitable for the prevention and treatment ofCOVID-19. The COVID causing virus is mainly transmitted through cough or sneeze droplets generated by an infected person. Hence its early and accurate diagnosis appears essential for minimizing spread, prevention and eventually containment of the pandemic. Also, since the clinical presentation of the COVID infection is varied starting from asymptomatic to severe cases, it reinforces the need for detection methods that are simple, early and with good sensitivity and specificity. This article reviews impact of potassium ions in functioning of various organs in humans and its possible role in COVID disease progression.

scholarly journals Prevalence of Urinary Schistosomiasis in Migrants in Apulia, a Region of Southern Italy, in the Years 2006–2016

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Gaetano Brindicci ◽  
Carmen Rita Santoro ◽  
Vittoriana De Laurentiis ◽  
Carmen Capolongo ◽  
Maria Elena Solarino ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
World Health ◽  
Epidemiological Surveillance ◽  
Urinary Schistosomiasis ◽  
South Italy ◽  
Clinical Observations ◽  
The World ◽  
Before And After ◽  
Study Population ◽  
Health Organization

Schistosomiasis is the most prevalent tropical disease in the world after malaria. According to the World Health Organization, the disease afflicts more than 240 million people in about 80 countries. Recently, an epidemiological surveillance study performed between 1997 and 2010 by the European Network for Tropical Medicine and Health Travel regarding schistosomiasis between immigrants and travelers has been published. No data are available in the literature regarding the situation in South Italy. Herein, we report the prevalence of urinary schistosomiasis in a population of migrants in Apulia referring to our outpatient clinic for immigrant diseases in the period 2006–2016. Since all cases of schistosomiasis were related to the last three years of observation, the demographic and clinical characteristics of the study population were compared before and after 2014. Nearly 51% of all patients visited (1762) were from high/moderate endemic countries for schistosomiasis, and nine cases of urinary schistosomiasis were diagnosed. Prevalence was 1% among migrants from endemic areas and 10% in those from Mali and Senegal. Our findings confirm that schistosomiasis is a widespread infection among immigrants, even if it is often underdiagnosed because of the multifaceted clinical presentation. Changes in migratory dynamics can affect clinical observations very quickly.

scholarly journals Ocular manifestations of COVID-19: a literature review

2020 ◽  
Vol 66 (9) ◽  
pp. 1296-1300
Author(s):  
Bruna Rafaella Santos Torres ◽  
Carlos Eduardo Ximenes da Cunha ◽  
Laís Rytholz Castro ◽  
Lara Medeiros Pirauá de Brito ◽  
Caio Victor Oliveira Ferreira ◽  
...  
Keyword(s):  
Literature Review ◽  
Clinical Presentation ◽  
Clinical Manifestations ◽  
World Health ◽  
The Novel ◽  
Highly Pathogenic ◽  
Ocular Manifestations ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization

SUMMARY Coronavirus disease 2019 (COVID-19) caused by the highly pathogenic SARS-Cov-2 virus, was declared as a pandemic by the World Health Organization (WHO) in March 2020. Its main clinical manifestations are related to airway involvement; however, there is extrapulmonary impairment in some cases. Given this context, this literature review aims to identify the ophthalmological conditions caused by infection with the novel coronavirus. Although ocular findings do not include the standard clinical presentation of the disease, there are reports of some ophthalmological changes in COVID-19 patients, and conjunctivitis is the most common among these.

Sign in / Sign up

Export Citation Format

Share Document