Are COPD patients with Nocardia species identification different from those who have also co-morbid bronchiectasis?

2020 ◽  
Author(s):  
Mariana Serino ◽  
Catarina Sousa ◽  
Margarida Redondo ◽  
Natália Martins ◽  
Adelina Amorim
Keyword(s):  
Species Identification ◽  
Nocardia Species ◽  
Copd Patients

Characteristics of nocardiosis patients with different immune status from a Chinese tertiary general hospital during 8-year period

2019 ◽  
Author(s):  
Lei Huang ◽  
Liying Sun ◽  
Yan Yan
Keyword(s):  
Soft Tissue ◽  
General Hospital ◽  
Species Identification ◽  
Clinical Data ◽  
Antibiotic Susceptibility ◽  
Clinical Characteristics ◽  
Kidney Diseases ◽  
Test Method ◽  
Chronic Kidney Diseases ◽  
Nocardia Species

Abstract Background: Nocardia is an opportunistic pathogen from environment, which is generally thought to infect immunosuppressed patients (ISPs), but recent studies showed it could also cause infections in immunocompetent patients (ICPs). Objective: To compare the clinical characteristics, patients’ outcome, Nocardia species identification and antibiotic susceptibility profiles of nocardiosis between ICPs and ISPs. Methods: The detailed clinical data were collected from all the non-repetitive nocardiosis patients during 2011 and 2018, from a tertiary general hospital in Beijing, China. Then each Nocardia isolate was identified to species level by DNA sequencing. The antibiotic susceptibility testing was performed by E-test method, and interpreted following CLSI M24 document. The clinical and microbiological characteristics between ICPs and ISPs were compared statistically. Results: A total of 23 non-repetitive nocardiosis patients with detailed clinical data were enrolled in this study. Among them, 9 were ICPs and 14 were ISPs. All the skin and soft tissue infections occurred in ICPs (33.3% versus 0%, P<0.05). Bronchiectasis occurred more frequently in ICPs (44.4% versus 21.4%), while chronic kidney diseases and co-infection with aspergillosis occurred more frequently in ISPs (35.7% versus 0%, 35.7% versus 0%, respectively), although they did not reach the statistical significance. There were no significant difference in other clinical characteristics, Nocardia species identification, and antibiotic susceptibility between ISPs and ICPs (P>0.05). Conclusion: Nocardiosis could occur in both ISPs and ICPs. Skin and soft tissue infection and bronchiectasis occurred more frequently in ICPs. Chronic kidney diseases and co-infection with aspergillosis occurred more frequently in ISPs. These characteristics should be noticed by physicians in diagnosis of nocardiosis.

scholarly journals Multiplex quantitative PCR for Streptococci species identification and detection of genetic drug resistance markers in COPD patients

2014 ◽  
pp. 40-48
Author(s):  
L. N. Ikryannikova ◽  
M. E. Senina ◽  
E. S. Lisitsina ◽  
L. M. Ogorodova ◽  
S. V. Fedosenko ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Species Identification ◽  
Quantitative Pcr ◽  
Copd Patients ◽  
Resistance Markers

Chemical Species Identification in an SEM by Changes in Emitted X-Ray Energies

1974 ◽  
Vol 32 ◽  
pp. 570-571
Author(s):  
R. H. Duff
Keyword(s):  
Species Identification ◽  
Valence Electron ◽  
Chemical Species ◽  
X Rays ◽  
Chemical Bonds ◽  
Small Shift ◽  
X Ray ◽  
Electron Transitions ◽  
Peak Energy ◽  
Chemical Combination

A material irradiated with electrons emits x-rays having energies characteristic of the elements present. Chemical combination between elements results in a small shift of the peak energies of these characteristic x-rays because chemical bonds between different elements have different energies. The energy differences of the characteristic x-rays resulting from valence electron transitions can be used to identify the chemical species present and to obtain information about the chemical bond itself. Although these peak-energy shifts have been well known for a number of years, their use for chemical-species identification in small volumes of material was not realized until the development of the electron microprobe.

Oral and Oropharyngeal Sensory Function in Adults With Chronic Obstructive Pulmonary Disease

2020 ◽  
Vol 29 (2) ◽  
pp. 864-872
Author(s):  
Fernanda Borowsky da Rosa ◽  
Adriane Schmidt Pasqualoto ◽  
Catriona M. Steele ◽  
Renata Mancopes
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Oral Cavity ◽  
Pulmonary Disease ◽  
Thermal Sensation ◽  
Sensory Function ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Age Related ◽  
Copd Patients

Introduction The oral cavity and pharynx have a rich sensory system composed of specialized receptors. The integrity of oropharyngeal sensation is thought to be fundamental for safe and efficient swallowing. Chronic obstructive pulmonary disease (COPD) patients are at risk for oropharyngeal sensory impairment due to frequent use of inhaled medications and comorbidities including gastroesophageal reflux disease. Objective This study aimed to describe and compare oral and oropharyngeal sensory function measured using noninstrumental clinical methods in adults with COPD and healthy controls. Method Participants included 27 adults (18 men, nine women) with a diagnosis of COPD and a mean age of 66.56 years ( SD = 8.68). The control group comprised 11 healthy adults (five men, six women) with a mean age of 60.09 years ( SD = 11.57). Spirometry measures confirmed reduced functional expiratory volumes (% predicted) in the COPD patients compared to the control participants. All participants completed a case history interview and underwent clinical evaluation of oral and oropharyngeal sensation by a speech-language pathologist. The sensory evaluation explored the detection of tactile and temperature stimuli delivered by cotton swab to six locations in the oral cavity and two in the oropharynx as well as identification of the taste of stimuli administered in 5-ml boluses to the mouth. Analyses explored the frequencies of accurate responses regarding stimulus location, temperature and taste between groups, and between age groups (“≤ 65 years” and “> 65 years”) within the COPD cohort. Results We found significantly higher frequencies of reported use of inhaled medications ( p < .001) and xerostomia ( p = .003) in the COPD cohort. Oral cavity thermal sensation ( p = .009) was reduced in the COPD participants, and a significant age-related decline in gustatory sensation was found in the COPD group ( p = .018). Conclusion This study found that most of the measures of oral and oropharyngeal sensation remained intact in the COPD group. Oral thermal sensation was impaired in individuals with COPD, and reduced gustatory sensation was observed in the older COPD participants. Possible links between these results and the use of inhaled medication by individuals with COPD are discussed.

P. aeruginosa Worse Among Hospitalized COPD Patients

2006 ◽  
Vol 39 (11) ◽  
pp. 62
Author(s):  
PATRICE WENDLING
Keyword(s):  
Copd Patients

Combo Therapy Cuts Mortality in COPD Patients

2006 ◽  
Vol 36 (22) ◽  
pp. 4
Author(s):  
BRUCE JANCIN
Keyword(s):  
Copd Patients
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