Persistent symptoms and quality of life after novel coronavirus infection (COVID-19)

The aim of the study was to research the hyperbaric oxygenation effect on the condition of patients in the course of complex treatment aimed at rehabilitation after suffering from COVID-19 pneumonia. Results: the impact of hyperbaric oxygenation on the body of patients who have suffered from the novel coronavirus infection provides a positive dynamics and improves their quality of life. Conclusion: in the process of rehabilitating patients who have undergone the new coronavirus infection, it is necessary to use various physiotherapeutic measures, including hyperbaric oxygenation.

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What’s going on following acute covid-19? Clinical characteristics of patients in an out-patient rehabilitation program

Neurorehabilitation ◽

10.3233/nre-210025 ◽

2021 ◽

pp. 1-12

Author(s):

Sergiu Albu ◽

Nicolas Rivas Zozaya ◽

Narda Murillo ◽

Alberto Garcia-Molina ◽

Cristian Andres Figueroa Chacón ◽

...

Keyword(s):

Quality Of Life ◽

Cognitive Impairment ◽

Acute Infection ◽

Rehabilitation Program ◽

Neuropsychological Impairment ◽

Outpatient Rehabilitation ◽

Screening Process ◽

Icu Patients ◽

Persistent Symptoms

BACKGROUND: Coronavirus disease 2019 (COVID-19) patients present long-lasting physical and neuropsychological impairment, which may require rehabilitation. OBJECTIVES: The current cross-sectional study characterizes post COVID-19 sequelae and persistent symptoms in patients in an outpatient rehabilitation program. METHODS: Thirty patients [16 post-ICU and 14 non-ICU; median age = 54(43.8–62) years; 19 men] presenting sequelae and/or persistent symptoms (>3 months after acute COVID-19) were selected of 41 patients referred for neurorehabilitation. Patients underwent physical, neuropsychological and respiratory evaluation and assessment of impact of fatigue and quality of life. RESULTS: The main reasons for referral to rehabilitation were: fatigue (86.6%), dyspnea (66.7%), subjective cognitive impairment (46.7%) and neurological sequelae (33.3%). Post-ICU patient presented sequelae of critical illness myopathy and polyneuropathy, stroke and encephalopathy and lower forced vital capacity compared to non-ICU patients. Cognitive impairment was found in 63.3% of patients, with a similar profile in both sub-groups. Increased physical fatigue, anxiety and depression and low quality of life were prevalent irrespective of acute COVID-19 severity. CONCLUSIONS: The variability of post COVID-19 physical and neuropsychological impairment requires a complex screening process both in ICU and non-ICU patients. The high impact of persistent symptoms on daily life activities and quality of life, regardless of acute infection severity, indicate need for rehabilitation.

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Functional outcomes and quality of life during long-term follow-up after acute pulmonary embolism: analysis of the prospective multicentre FOCUS study

European Heart Journal ◽

10.1093/ehjci/ehaa946.2277 ◽

2020 ◽

Vol 41 (Supplement_2) ◽

Cited By ~ 1

Author(s):

S Barco ◽

L Valerio ◽

M Jankowski ◽

M.M Hoeper ◽

F.A Klok ◽

...

Keyword(s):

Quality Of Life ◽

Pulmonary Embolism ◽

Acute Pulmonary Embolism ◽

Medical Center ◽

Combination Group ◽

Funding Source ◽

Median Score ◽

Persistent Symptoms

Abstract Background It is unclear to which extent persistence of symptoms and/or residual haemodynamic impairment clinical course of pulmonary embolism are associated with worse quality of life (QoL). Aims To study the correlation between symptoms and haemodynamic impairment with QoL during the first year after acute pulmonary embolism (PE). Methods The Follow-Up after acute pulmonary embolism (FOCUS) study prospectively enrolled and followed consecutive adult patients diagnosed with acute symptomatic objectively diagnosed PE. In the present analysis, we considered patients who completed the Pulmonary Embolism QoL (PEmb-QoL) Questionnaire at predefined visits 3 and 12 months after acute PE. The PEmb-QoL score ranges from 0% (best QoL) to 100% (worst QoL). We evaluated at these two time points the correlation between persisting symptoms (group: symptoms), elevation of natriuretic peptides or residual right ventricular dysfunction (group: RVD), or their combination (group: symptoms + RVD) and QoL. Results A total of 617 patients were included; their median age was 62 years, 44% were women; 8% had active cancer, and 21% previous venous thromboembolism. At 3 months, patients with neither symptoms nor RVD (n=302) had the highest quality of life (median score 18%, 25th–75th percentile: 8%–34%), followed by those without symptoms but with RVD (n=255; median score 19%, 25th–75th percentile: 7%–34%), and by those with symptoms only (n=131; median PEmb-QoL 31%, 25th–75th percentile: 18%–49%). Patients with both symptoms and RVD (n=170) had the worst quality of life (median score 38%, 25th–75th percentile: 19%–53%); Figure 1A. At 12 months, we found an overall improvement of PEmb-QoL score. The degree of this QoL improvement varied across groups, being largest for patients who recovered from having symptoms + RVD at 3 months to normalization of at least one at 12 months. The change in QoL from 3 to 12 months was smaller both in patients who had neither symptoms nor RVD and in patients who had no recovery in either symptoms or RVD; Figure 1B. Conclusions Persistent symptoms after PE, especially in patients with elevated biomarkers or residual echocardiographic dysfunction, were the main drivers of QoL at 3 months as well as of the course of QoL over time. Figure 1 Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): University Medical Center of the Johannes Gutenberg University, Mainz, Germany; German Federal Ministry of Education and Research

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Neuromodulation for Mild Traumatic Brain Injury Rehabilitation: A Systematic Review

Frontiers in Human Neuroscience ◽

10.3389/fnhum.2020.598208 ◽

2020 ◽

Vol 14 ◽

Author(s):

Francesca Buhagiar ◽

Melinda Fitzgerald ◽

Jason Bell ◽

Fiona Allanson ◽

Carmela Pestell

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Traumatic Brain Injury ◽

Brain Injury ◽

Mild Traumatic Brain Injury ◽

Post Intervention ◽

Persistent Symptoms ◽

Positive Effects ◽

The Brain

Background: Mild traumatic brain injury (mTBI) results from an external force to the head or body causing neurophysiological changes within the brain. The number and severity of symptoms can vary, with some individuals experiencing rapid recovery, and others having persistent symptoms for months to years, impacting their quality of life. Current rehabilitation is limited in its ability to treat persistent symptoms and novel approaches are being sought to improve outcomes following mTBI. Neuromodulation is one technique used to encourage adaptive neuroplasticity within the brain.Objective: To systematically review the literature on the efficacy of neuromodulation in the mTBI population.Method: A systematic review was conducted using Medline, Embase, PsycINFO, PsycARTICLES and EBM Review. Preferred Reporting Items for Systematic Reviews and the Synthesis Without Meta-analysis reporting guidelines were used and a narrative review of the selected studies was completed. Fourteen articles fulfilled the inclusion criteria which were published in English, investigating an adult sample and using a pre- and post-intervention design. Studies were excluded if they included non-mild TBI severities, pediatric or older adult populations.Results: Thirteen of fourteen studies reported positive reductions in mTBI symptomatology following neuromodulation. Specifically, improvements were reported in post-concussion symptom ratings, headaches, dizziness, depression, anxiety, sleep disturbance, general disability, cognition, return to work and quality of life. Normalization of working memory activation patterns, vestibular field potentials, hemodynamics of the dorsolateral prefrontal cortex and excessive delta wave activity were also seen. The studies reviewed had several methodological limitations including small, heterogenous samples and varied intervention protocols, limiting generalisability. Further research is required to understand the context in which neuromodulation may be beneficial.Conclusions: While these positive effects are observed, limitations included unequal representation of neuromodulation modalities in the literature, and lack of literature describing the efficacy of neuromodulation on the development or duration of persistent mTBI symptoms. Better clarity regarding neuromodulation efficacy could have a significant impact on mTBI patients, researchers, clinicians, and policy makers, facilitating a more productive post-mTBI population. Despite the limitations, the literature indicates that neuromodulation warrants further investigation. PROSPERO registration number: CRD42020161279.

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Quality of Life and Symptom Burden 1 Month After Concussion in Children and Adolescents

Clinical Pediatrics ◽

10.1177/0009922818806308 ◽

2018 ◽

Vol 58 (1) ◽

pp. 42-49 ◽

Cited By ~ 4

Author(s):

David R. Howell ◽

Julie C. Wilson ◽

Michael W. Kirkwood ◽

Joseph A. Grubenhoff

Keyword(s):

Quality Of Life ◽

Physical Health ◽

Children And Adolescents ◽

Symptom Burden ◽

Psychosocial Health ◽

Post Injury ◽

Persistent Symptoms ◽

Patient Reported ◽

A Prospective Study

We conducted a prospective study of children and adolescents (n = 176; mean age = 13.0 ±2.7 years; 38% female) assessed acutely post-concussion and again 30 days later. We investigated the association between symptom burden and quality of life (QOL) outcomes, as well as the effect of age on QOL. We assessed QOL using patient-reported Pediatric Quality of Life Inventory 4.0, and symptoms using the Health and Behavior Inventory (HBI). Acute (<2 days post-injury) HBI ratings demonstrated a low correlation ( R2 = 0.08) with physical health QOL and a moderate correlation with psychosocial health QOL ( R2 = 0.21) 30 days post-concussion. HBI ratings 30 days post-concussion demonstrated a moderately high correlation with physical health QOL ( R2 = 0.35) and psychosocial health QOL ( R2 = 0.57). Age was not significantly associated with physical or psychosocial QOL ratings. Impairments in QOL following concussion may identify children and adolescents who need additional referral to address persistent symptoms at this time.

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The dynamics of recovery processes of physical activity of people who recovered from COVID-19

LAPLAGE EM REVISTA ◽

10.24115/s2446-6220202173c1667p.607-612 ◽

2021 ◽

Vol 7 (3C) ◽

pp. 607-612

Author(s):

Sergey Kokhan ◽

Elena Romanova ◽

Vladislav Dychko ◽

Elena Dychko ◽

Danil Dychko ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Life Assessment ◽

Control Group ◽

Breathing Exercises ◽

Rehabilitation Programs ◽

Recovery Processes ◽

Coronavirus Infection ◽

The Impact

The article shows the results of physical therapy of those who have had coronavirus infection COVID-19 and who have completed a month's course of physical rehabilitation as a part of rehabilitation measures in the conditions of the innovative clinic "Academy of Health". The aim of the research is to study the impact of pulmonary rehabilitation programs for patients with moderate to severe COVID-19. The implementation of special breathing exercises made it possible to improve the oxygen saturation in the blood, to reduce shortness of breath and indicators of respiratory symptoms. The tolerance to exercise has increased; physical activity and the quality of life of patients with pneumonia associated with COVID-19 have improved. The best results of the EQ-5D quality of life assessment were recorded in the experimental group compared to the control group.

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Experience in the use of telerehabilitation after a COVID-19 infection at the polyclinic stage in Tyumen

Medical Science And Education Of Ural ◽

10.36361/1814-8999-2021-22-2-84-88 ◽

2021 ◽

Vol 22 (2) ◽

pp. 84-88

Author(s):

T. I. Kutergina ◽

◽

O. V. Andreeva ◽

E. F. Turovinina ◽

T. M. Kleshchevnikova ◽

...

Keyword(s):

Quality Of Life ◽

Health Status ◽

The State ◽

Medical Rehabilitation ◽

Medical Institution ◽

Shortness Of Breath ◽

Early Start ◽

Coronavirus Infection ◽

Medical University

Aim. To evaluate the effectiveness of the early start of medical rehabilitation, after a coronavirus infection, with the use of telemedicine technologies at the polyclinic stage. Material and methods. A study was conducted on the basis of the State Medical Institution “City Polyclinic No. 17” with the participation of 65 patients who had pneumonia against the background of COVID-19 infection at the age of 29 to 81 years inclusive, the average age was 54 ± 13.0 years, receiving rehabilitation at the 3rd stage using telemedicine technologies. Results. The Department of Medical Prevention and Rehabilitation of the INPR of the Tyumen State Medical University has developed a “Program of medical rehabilitation of patients who have suffered a new coronavirus infection at the polyclinic stage with the use of telemedicine technologies”. Implemented and implemented on the basis of the State Medical Institution “City Polyclinic No. 17” in Tyumen. Earlier, the beginning of rehabilitation measures at the outpatient stage in patients after pneumonia on the background of COVID-19 infection eliminates shortness of breath in patients with a mild course, with a moderate-severe and severe course restores by 60%. Recovery of muscle strength was noted in all patients. Positive dynamics in the normalization of the psychoemotional background and improvement of the quality of life were reliably obtained. Conclusion. Medical rehabilitation with the use of telemedicine technologies is an effective approach of the healthcare system in restoring the health status of patients who have suffered a coronavirus infection.

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Work of the clinical expert department of the ophthalmosurgical clinic in the context of a pandemic of the novel coronavirus disease

Modern technologies in ophtalmology ◽

10.25276/2312-4911-2021-1-9-14 ◽

2021 ◽

pp. 9-14

Author(s):

O.B. Baleva ◽

◽

N.V. Savchenko ◽

V.V. Egorov ◽

◽

...

Keyword(s):

Social Distance ◽

State Institution ◽

Insurance Companies ◽

Medical Documentation ◽

Federal State ◽

The Novel ◽

Coronavirus Infection ◽

Novel Coronavirus ◽

Clinical Expert

Changes in work of the clinical expert department of the Khabarovsk branch of the S. Fyodorov Eye Microsurgery Federal State Institution (the Khabarovsk branch) in the context of a pandemic of the novel coronavirus disease were analyzed in the article. The difficulties that have appeared in all sections of the work performed are described, both medical and expert: the time for checking the quality of filling out medical documentation has increased due to the identification of a larger number of defects; the time for medical control and discharge of patients from the hospital has increased due to the impossibility of accumulating patients in one place and the need to maintain social distance; difficulties arose in working with experts from insurance companies due to the lack of direct communication (medical records are checked outside the Khabarovsk branch). The concern of people about the possibility of carrying out surgical treatment in conditions of coronavirus infection was expressed in an increase in the information load of the «Question - Answer» section on the website of the Khabarovsk branch and, accordingly, on the doctors in the clinical expert department working with it. Key words: pandemic, COVID-19, SARSCoV-2, anti-epidemic measures, personal protective equipment, social distance, treatment control, medical documentation, medical and economic expertise.

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