scholarly journals Osteopontin, asbestos exposure and pleural plaques: a cross-sectional study

2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Giuseppe Mastrangelo ◽  
Gianluca Marangi ◽  
Maria N Ballarin ◽  
Silvia Michilin ◽  
Aline SC Fabricio ◽  
...  
Keyword(s):  
Asbestos Exposure ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Pleural Plaques

scholarly journals The role of polymorphisms in glutathione-related genes in asbestos-related diseases

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Alenka Franko ◽  
Katja Goricar ◽  
Metoda Dodic Fikfak ◽  
Viljem Kovac ◽  
Vita Dolzan
Keyword(s):  
Logistic Regression ◽  
Asbestos Exposure ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Related Disease ◽  
Pleural Plaques ◽  
Asbestos Related Disease

Abstract Background The study investigated the influence of GCLC, GCLM, GSTM1, GSTT1 and GSTP1 polymorphisms, as well as the influence of interactions between polymorphism and interactions between polymorphisms and asbestos exposure, on the risk of developing pleural plaques, asbestosis and malignant mesothelioma (MM). Subjects and methods The cross sectional study included 940 asbestos-exposed subjects, among them 390 subjects with pleural plaques, 147 subjects with asbestosis, 225 subjects with MM and 178 subjects with no asbestos-related disease. GCLC rs17883901, GCLM rs41303970, GSTM1 null, GSTT1 null, GSTP1 rs1695 and GSTP1 rs1138272 genotypes were determined using PCR based methods. In statistical analysis, logistic regression was used. Results GSTT1 null genotype was associated with the decreased risk for pleural plaques (OR = 0.63; 95% CI = 0.40–0.98; p = 0.026) and asbestosis (OR = 0.51; 95% CI = 0.28–0.93; p = 0.028), but not for MM. A positive association was found between GSTP1 rs1695 AG + GG vs. AA genotypes for MM when compared to pleural plaques (OR = 1.39; 95% CI = 1.00–1.94; p = 0.049). The interactions between different polymorphisms showed no significant influence on the risk of investigated asbestos-related diseases. The interaction between GSTT1 null polymorphism and asbestos exposure decreased the MM risk (OR = 0.17; 95% CI = 0.03–0.85; p = 0.031). Conclusions Our findings suggest that GSTT1 null genotype may be associated with a decreased risk for pleural plaques and asbestosis, may modify the association between asbestos exposure and MM and may consequently act protectively on MM risk. This study also revealed a protective effect of the interaction between GSTP1 rs1695 polymorphism and asbestos exposure on MM risk.

Natural carcinogenic fiber and pleural plaques assessment in a general population: A cross-sectional study

2016 ◽  
Vol 150 ◽  
pp. 23-29 ◽  
Author(s):  
Caterina Ledda ◽  
Cristoforo Pomara ◽  
Massimo Bracci ◽  
Dario Mangano ◽  
Vincenzo Ricceri ◽  
...  
Keyword(s):  
General Population ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Pleural Plaques

scholarly journals Asbestos-Related Malignant Mesothelioma in The South of Iran: A Cross-Sectional Study

2021 ◽  
Author(s):  
Alireza Rezvani ◽  
Sahar Jahanshahi ◽  
Damoun Fouladi ◽  
Bizhan Ziaian ◽  
Mohammad Javad Fallahi ◽  
...  
Keyword(s):  
Malignant Mesothelioma ◽  
Asbestos Exposure ◽  
Cross Sectional Study ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Rare Malignancy ◽  
The Relationship ◽  
Oil Company

Abstract Objective: Malignant Mesothelioma (MM) is a rare malignancy of the serosa membranes with a high mortality rate and long latent period. The relationship between a group of mineral fibers known as asbestos and mesothelioma is now well accepted in which people can be exposed to these fibers by various means during their lifetime.Method: In this study, we analyzed the demographic features and occupations of confirmed cases of MM in Shiraz, southern Iran along with the follow-up of the patients' disease from 2008 to 2018.Results: Among the 35 confirmed cases of MM with an average of 61 years, 9 (25.7%) were female and 26 (74.3%) were male. At the time 12 patients have already died with a mean of 11.26 months after diagnosis. Our results showed a higher prevalence of MM among housekeepers and oil company employees. Compared to the control group, we concluded that employees of the oil company are at a high risk of MM in Iran. Also, individuals living near refinery locations had higher MM rates.Conclusion: Exposure with asbestos, either through occupation or proximate living location to a source, had a significant correlation with MM occurrence. MM can be prevented if asbestos exposure is reduced.

scholarly journals Asbestos-Related Malignant Mesothelioma in The South of Iran: A Cross-Sectional Study

2020 ◽  
Author(s):  
Alireza Rezvani ◽  
Sahar Jahanshahi ◽  
Damoun Fouladi ◽  
Bizhan Ziaian ◽  
Mohammad Javad Fallahi ◽  
...  
Keyword(s):  
Malignant Mesothelioma ◽  
Asbestos Exposure ◽  
Cross Sectional Study ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Rare Malignancy ◽  
The Relationship ◽  
Oil Company

Abstract Background: Malignant Mesothelioma (MM) is a rare malignancy of the serosa membranes with a high mortality rate and long latent period. The relationship between a group of mineral fibers known as asbestos and mesothelioma is now well accepted in which people can be exposed to these fibers by various means during their lifetime. In addition to occupations directly in contact with asbestos such as asbestos mines and factories, certain occupations are much more at risk of MM due to extensive use of asbestos in industry. Several studies have been conducted to identify these occupations.Method: In this study, we analyzed the demographic features and occupations of confirmed cases of MM in Shiraz, southern Iran along with the follow-up of the patients' disease from 2008 to 2018.Results: Among the 35 confirmed cases of MM with an average of 61 years, 9 (25.7%) were female and 26 (74.3%) were male. At the time 12 patients have already died with a mean of 11.26 months after diagnosis. Our results showed a higher prevalence of MM among housekeepers and oil company employees. Compared to the control group, we concluded that employees of the oil company are at a high risk of MM in Iran. Also, individuals living near refinery locations had higher MM rates. Conclusion: Our study demonstrated that exposure with asbestos, either through occupation or proximate living location to a source, had a significant correlation with MM occurrence. MM can be prevented if asbestos exposure is reduced.

Does a Graduate Course in Fluency Disorders Make a Difference?

2010 ◽  
Vol 20 (1) ◽  
pp. 10-14 ◽  
Author(s):  
Evelyn R. Klein ◽  
Barbara J. Amster
Keyword(s):  
Undergraduate Students ◽  
Graduate Programs ◽  
The United States ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Graduate Course ◽  
Cross Sectional ◽  
Fluency Disorders ◽  
Introductory Course ◽  
Communicative Disorders

Abstract A study by Yaruss and Quesal (2002), based on responses from 134 of 239 ASHA accredited graduate programs, indicated that approximately 25% of graduate programs in the United States allow students to earn their degree without having coursework in fluency disorders and 66% of programs allow students to graduate without clinical experience treating people who stutter (PWS). It is not surprising that many clinicians report discomfort in treating PWS. This cross-sectional study compares differences in beliefs about the cause of stuttering between freshman undergraduate students enrolled in an introductory course in communicative disorders and graduate students enrolled and in the final weeks of a graduate course in fluency disorders.

Confidence toward vaccination as reported by parents of children admitted to a tertiary care hospital in Riyadh, Saudi Arabia: A cross sectional study

Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional

Conflict Avoidance in Old Age

GeroPsych ◽  
2017 ◽  
Vol 30 (2) ◽  
pp. 61-70 ◽  
Author(s):  
Lia Oberhauser ◽  
Andreas B. Neubauer ◽  
Eva-Marie Kessler
Keyword(s):  
Social Support ◽  
Perceived Social Support ◽  
Well Being ◽  
Cross Sectional Study ◽  
Conflict Avoidance ◽  
Subjective Well Being ◽  
Sectional Study ◽  
Cross Sectional ◽  
Adult Lifespan ◽  
Set Up

Abstract. Conflict avoidance increases across the adult lifespan. This cross-sectional study looks at conflict avoidance as part of a mechanism to regulate belongingness needs ( Sheldon, 2011 ). We assumed that older adults perceive more threats to their belongingness when they contemplate their future, and that they preventively react with avoidance coping. We set up a model predicting conflict avoidance that included perceptions of future nonbelonging, termed anticipated loneliness, and other predictors including sociodemographics, indicators of subjective well-being and perceived social support (N = 331, aged 40–87). Anticipated loneliness predicted conflict avoidance above all other predictors and partially mediated the age-association of conflict avoidance. Results suggest that belongingness regulation accounts may deepen our understanding of conflict avoidance in the second half of life.

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