scholarly journals The impact of repeated marathon running on cardiovascular function in the aging population

2012 ◽  
Vol 14 (1) ◽  
pp. 58 ◽  
Author(s):  
Erin Karlstedt ◽  
Anjala Chelvanathan ◽  
Megan Da Silva ◽  
Kelby Cleverley ◽  
Kanwal Kumar ◽  
...  
2020 ◽  
Vol 20 (13) ◽  
pp. 1287-1299
Author(s):  
Muhammad Akram Mohd Noordin ◽  
Mahanem Mat Noor ◽  
Wan Mohd Aizat

It is expected that in 2050, there will be more than 20% of senior citizens aged over 60 years worldwide. Such alarming statistics require immediate attention to improve the health of the aging population. Since aging is closely related to the loss of antioxidant defense mechanisms, this situation eventually leads to numerous health problems, including fertility reduction. Furthermore, plant extracts have been used in traditional medicine as potent antioxidant sources. Although many experiments had reported the impact of various bioactive compounds on aging or fertility, there is a lack of review papers that combine both subjects. In this review, we have collected and discussed various bioactive compounds from 26 different plant species known to affect both longevity and fertility. These compounds, including phenolics and terpenes, are mostly involved in the antioxidant defense mechanisms of diverse organisms such as rats, mites, fruit flies, roundworms, and even roosters. A human clinical trial should be considered in the future to measure the effects of these bioactive compounds on human health and longevity. Ultimately, these plant-derived compounds could be developed into health supplements or potential medical drugs to ensure a healthy aging population.


2017 ◽  
Vol 38 (8) ◽  
pp. e285-e288 ◽  
Author(s):  
Brent Jerome Wilkerson ◽  
Sandra F. Porps ◽  
Seilesh C. Babu

Gerontology ◽  
2018 ◽  
Vol 64 (6) ◽  
pp. 612-622 ◽  
Author(s):  
Altaf Engineer ◽  
Esther M. Sternberg ◽  
Bijan Najafi

Background: With the increasing global population of older adults, there is a need for environmental interventions that directly affect their physical, psychological, and emotional well-being to help them maintain or regain their independence and autonomy – all of which promote longevity. Methods: To better understand potential opportunities and challenges associated with interior design and “future homes” that may promote well-being, aging in place, and independent living in older adults, the authors reviewed relevant literature and included their own expert opinions from a multidisciplinary point of view including interior design, wellness, and engineering. Results: After summarizing existing environmental interventions for the aging population and their effectiveness, this review reveals knowledge gaps in interior design for the well-being and longevity of older adults followed by a discussion of opportunities for future research that may fill these gaps. Some of these opportunities include finding habilitative design strategies that identify and address unique situational needs of each user, advancing multidisciplinary fields such as environmental gerontology that recreate security and independence for older adults even outside of their homes, implementing technically advanced design strategies, which are flexible and adaptive to individual needs; and integrating the Internet of things (IoT) into living environments, including voice-activated command technologies to improve seniors’ central role in enabling an optimized healthcare ecosystem. Conclusions: Knowledge of current evidence regarding the impact of different environmental factors may hasten adaptation of well-designed innovations that can provide optimal healing and living environments for the aging population. By effectively addressing older adults’ unique and specialized needs, design practitioners can become an indispensable part of their medical, social, and environmental team. One of the rapidly developing infrastructures promising to revolutionize the design of “future homes” is the IoT. While it is at an early stage of development, ultimately we envisage a connected home using voice-controlled technology and Bluetooth-radio-connected add-ons, to augment much of what home health does today. Bringing these approaches together into an effective strategy for a model of effective geriatric care is important and needs to become an integral part of both design education and practice.


2020 ◽  
Vol 11 (1) ◽  
pp. 93-97
Author(s):  
Simran Bhullar

Electronic cigarettes (ECs) have quickly gained popularity among adolescents and adults, and have begun to replace conventional cigarettes as a source of nicotine. Although little is known about the impact of the exposure of chemical constituents of ECs, two major constituents, propylene glycol and vegetable glycerin have been implicated as formaldehyde-releasing agents. The wide variety of EC flavours appeal to users of all ages with reports showing a positive correlation between EC use and sweet flavorings. In addition, although marketing strategies advertise ECs as tools to facilitate smoking cessation, the evidence supporting this role is weak. In terms of its effect on users with pre-existing cardiovascular diseases, the data is conflicting regarding whether ECs have an impact on cardiovascular function. Although it is obvious that their safety and efficacy needs to be better understood, it is nonetheless essential to review what the research conducted so far has shown.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 724-725
Author(s):  
Amanda Sokan ◽  
Tracy Davis

Abstract The COVID-19 pandemic has led to increased strains on the rapidly increasing aging population’s mental, emotional, and physiological health. COVID-19, which belongs to a family of respiratory viruses, was first detected in China before spreading to other parts of the globe. Due to underlying health conditions and weakened immune systems, the aging population is at greater risk for contracting COVID-19. To better prepare for a future pandemic, it is necessary to explore the psychosocial impacts of limited human interactions to make the aging population feel safer while mitigating harm to their mental and emotional health. The purpose of this study is to highlight the experiences of the aging population with COVID-19, including psychosocial, behavioral responses to the pandemic, and older adults’ overall well-being. We surveyed a total of 203 adults 55 and older regarding their experiences with the pandemic. Survey components included the COVID-19 Household Environment Scale (Behar-Zusman, Chavez, & Gattamorta, ND), selected items from the COVID-19 Impact Study and open-ended questions, the Generalized Anxiety Disorder Assessment (Williams et al., 2006), and the UCLA Loneliness Scale (Russell, Peplau, & Ferguson, 1978). Preliminary analyses indicate that most participants had not experienced any COVID-19 symptoms, nor did they know anyone who had passed away from the virus. However, participants did report loneliness and less family cohesion because of the pandemic. Findings from this study will be used to help older adults cope with the impact of the current pandemic and future pandemics.


2021 ◽  
Vol 11 (1-2) ◽  
pp. 262-288

This article offers an analysis of the impact of the severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic in Japan with regard to the healthcare sector. With unprecedented pressure from a rapidly aging population, state-sponsored initiatives have created new migration streams from Southeast Asia, diversifying attempts to procure healthcare personnel to address labor shortages. The article analyzes the recent evolution of this supply chain nexus and how it was reconfigured during the pandemic. It also highlights the fragile dependency that Japan now has on an emergent nexus with surrounding countries and the strategies it has taken to ameliorate the vagaries of the ongoing pandemic.


2022 ◽  
Vol 12 ◽  
Author(s):  
Zuzanna Lewicka-Potocka ◽  
Anna Maria Kaleta-Duss ◽  
Ewa Lewicka ◽  
Marcin Kubik ◽  
Anna Faran ◽  
...  

Moderate physical activity has a positive impact on health, although extreme forms of sport such as marathon running may trigger exercise-induced cardiac fatigue. The explicit distinction between the right ventricular (RV) physiological response to training and maladaptive remodeling has not yet been determined. In this study, we aimed to analyze the impact of running a marathon on RV mechanics in amateur athletes using three-dimensional (3D) echocardiography (ECHO) and the ReVISION method (RV separate wall motion quantification). A group of 34 men with a mean age of 40 ± 8 years who successfully finished a marathon underwent ECHO three times, i.e., 2 weeks before the marathon (stage I), at the marathon finish line (stage II), and 2 weeks after the marathon (stage III). The ECHO findings were then correlated with the concentrations of biomarkers related to myocardial injury and overload and also obtained at the three stages. On finishing the marathon, the amateur athletes were found to have a significant (p < 0.05) increase in end-diastolic (with a median of 51.4 vs. 57.0 ml/m2) and end-systolic (with a median of 24.9 vs. 31.5 ml/m2) RV volumes indexed to body surface area, reduced RV ejection fraction (RVEF) (with a median of 51.0% vs. 46.0%), and a decrease in RV radial shortening [i.e., radial EF (REF)] (with a mean of 23.0 ± 4.5% vs. 19.3 ± 4.2%), with other RV motion components remaining unchanged. The post-competition decrease in REF was more evident in runners with larger total volume of trainings (R2 = 0.4776, p = 0.0002) and higher concentrations of high-sensitivity cardiac troponin I (r = 0.43, p < 0.05) during the preparation period. The decrease in REF was more prominent in the training of marathoners more than 47 km/week. At stage II, marathoners with a more marked decrease in RVEF and REF had higher galectin-3 (Gal-3) levels (r = −0.48 and r = −0.39, respectively; p < 0.05). Running a marathon significantly altered the RV performance of amateur athletes. Transient impairment in RV systolic function resulted from decreased radial shortening, which appeared in those who trained more extensively. Observed ECHO changes correlated with the concentrations of the profibrotic marker Gal-3.


Sign in / Sign up

Export Citation Format

Share Document