scholarly journals Post-marathon Decline in Right Ventricular Radial Motion Component Among Amateur Sportsmen

2022 ◽  
Vol 12 ◽  
Author(s):  
Zuzanna Lewicka-Potocka ◽  
Anna Maria Kaleta-Duss ◽  
Ewa Lewicka ◽  
Marcin Kubik ◽  
Anna Faran ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Troponin I ◽  
Positive Impact ◽  
Systolic Function ◽  
Stage Ii ◽  
Moderate Physical Activity ◽  
Marathon Running ◽  
Amateur Athletes ◽  
Cardiac Fatigue ◽  
The Impact

Moderate physical activity has a positive impact on health, although extreme forms of sport such as marathon running may trigger exercise-induced cardiac fatigue. The explicit distinction between the right ventricular (RV) physiological response to training and maladaptive remodeling has not yet been determined. In this study, we aimed to analyze the impact of running a marathon on RV mechanics in amateur athletes using three-dimensional (3D) echocardiography (ECHO) and the ReVISION method (RV separate wall motion quantification). A group of 34 men with a mean age of 40 ± 8 years who successfully finished a marathon underwent ECHO three times, i.e., 2 weeks before the marathon (stage I), at the marathon finish line (stage II), and 2 weeks after the marathon (stage III). The ECHO findings were then correlated with the concentrations of biomarkers related to myocardial injury and overload and also obtained at the three stages. On finishing the marathon, the amateur athletes were found to have a significant (p < 0.05) increase in end-diastolic (with a median of 51.4 vs. 57.0 ml/m2) and end-systolic (with a median of 24.9 vs. 31.5 ml/m2) RV volumes indexed to body surface area, reduced RV ejection fraction (RVEF) (with a median of 51.0% vs. 46.0%), and a decrease in RV radial shortening [i.e., radial EF (REF)] (with a mean of 23.0 ± 4.5% vs. 19.3 ± 4.2%), with other RV motion components remaining unchanged. The post-competition decrease in REF was more evident in runners with larger total volume of trainings (R2 = 0.4776, p = 0.0002) and higher concentrations of high-sensitivity cardiac troponin I (r = 0.43, p < 0.05) during the preparation period. The decrease in REF was more prominent in the training of marathoners more than 47 km/week. At stage II, marathoners with a more marked decrease in RVEF and REF had higher galectin-3 (Gal-3) levels (r = −0.48 and r = −0.39, respectively; p < 0.05). Running a marathon significantly altered the RV performance of amateur athletes. Transient impairment in RV systolic function resulted from decreased radial shortening, which appeared in those who trained more extensively. Observed ECHO changes correlated with the concentrations of the profibrotic marker Gal-3.

Acute cardiac effects of marathon running

2010 ◽  
Vol 108 (5) ◽  
pp. 1148-1153 ◽  
Author(s):  
Justin E. Trivax ◽  
Barry A. Franklin ◽  
James A. Goldstein ◽  
Kavitha M. Chinnaiyan ◽  
Michael J. Gallagher ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Right Ventricular ◽  
Troponin I ◽  
Right Ventricular Ejection Fraction ◽  
Ventricular Ejection ◽  
Volume Index ◽  
Marathon Running ◽  
Ventricular Ejection Fraction ◽  
The Right

We sought to clarify the significance of cardiac dysfunction and to assess its relationship with elevated biomarkers by using cardiovascular magnetic resonance imaging in healthy, middle-aged subjects immediately after they ran 26.2 miles. Cardiac dysfunction and elevated blood markers of myocardial injury have been reported after prolonged strenuous exercise. From 425 volunteers, 13 women and 12 men were randomly selected, provided medical and training history, and underwent baseline cardiopulmonary exercise testing to exhaustion. Blood biomarkers, cardiovascular magnetic resonance imaging, and 24-h ambulatory electrocardiography were performed 4 wk before and immediately after the race. Participants were 38.7 ± 9.0 yr old, had baseline peak oxygen consumption of 52.9 ± 5.6 ml·kg−1·min−1, and completed the marathon in 256.2 ± 43.5 min. Cardiac troponin I and B-type natriuretic peptide increased following the race ( P = 0.001 and P < 0.0001, respectively). Cardiovascular magnetic resonance-determined pre- and postmarathon left ventricular ejection fractions were comparable, 57.7 ± 4.1% and 58.7 ± 4.3%, respectively ( P = 0.32). Right atrial volume index increased from 46.7 ± 14.4 to 57.0 ± 14.5 ml/m2( P < 0.0001). Similarly, right ventricular end-systolic volume index increased from 47.4 ± 11.2 to 57.0 ± 14.6 ml/m2( P < 0.0001) whereas the right ventricular ejection fraction dropped from 53.6 ± 7.1 to 45.5 ± 8.5% ( P < 0.0001). There were no morphological changes observed in the left atrium or ventricle or evidence of ischemic injury to any chamber by late gadolinium enhancement. There were no significant arrhythmias. Marathon running causes dilation of the right atrium and right ventricle, reduction of right ventricular ejection fraction, and release of cardiac troponin I and B-type natriuretic peptide but does not appear to result in ischemic injury to any chamber.

Changes in right ventricular longitudinal function: primary mitral and concomitant tricuspid valve repair

Perfusion ◽  
2018 ◽  
Vol 34 (4) ◽  
pp. 310-317 ◽  
Author(s):  
Rasa Ordienė ◽  
Paulius Orda ◽  
Jolanta Justina Vaškelytė ◽  
Neris Stoškutė ◽  
Eglė Kazakauskaitė ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Tricuspid Valve ◽  
Negative Impact ◽  
Systolic Function ◽  
Tissue Doppler ◽  
Control Group ◽  
Tricuspid Valve Repair ◽  
Longitudinal Function ◽  
The Impact ◽  
Longitudinal Strains

Objectives: To evaluate the impact of concomitant tricuspid valve (TV) repair on the right ventricular (RV) function postoperatively and within the 6 months following degenerative mitral valve (MV) repair. Methods: The prospective study included 37 patients (mean age 57.32 ± 2.13 years) with severe MV regurgitation due to primary MV prolapse. Nineteen underwent successful MV repair (TV(−) group). Additional TV repair due to moderate-to-severe TV regurgitation was performed in 18 (TV(+) group). Two-dimensional (2D) speckle-tracking and tissue Doppler echocardiography was performed for all patients before surgery and 7 days and 6 months after surgery. Results: Preoperative dimensions and indices of RV longitudinal function did not differ between the groups (right ventricle end-diastolic diameter (RVEDD) was 33.53 ± 0.94 mm vs. 34.67 ± 1.72 mm, tricuspid annular systolic motion (S’) was 15.06 ± 0.85 cm/s vs. 16.0 ± 1.27 cm/s, tricuspid annular plane systolic excursion (TAPSE) was 24.02 ± 1.06 mm vs. 22.4 ± 1.36 mm, respectively; p>0.05). RVEDD decreased significantly and did not change within the follow-up in the TV(−) group. In the TV(+) group, RVEDD decreased early after surgery and more markedly six months later in comparison to the TV(−) group. Indices of RV systolic longitudinal function decreased early after surgery and had a tendency to increase after six months in both groups. Regional longitudinal strains of the lateral RV wall decreased early after surgery and improved within the six months in the TV(−) group and did not change significantly in the TV(+) group. Conclusions: Additional TV repair in degenerative MV repair more markedly reduces RV dimensions and does not have a negative impact on RV systolic function in comparison to an isolated MV repair although these conclusions are of limited value due to the lack of a control group.

Longitudinal and radial systolic myocardial tissue velocities after prolonged exercise

2006 ◽  
Vol 31 (3) ◽  
pp. 256-260 ◽  
Author(s):  
Keith George ◽  
Rob Shave ◽  
David Oxborough ◽  
Greg Whyte ◽  
Ellen Dawson
Keyword(s):  
Tissue Doppler Imaging ◽  
Repeated Measures ◽  
Systolic Function ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Marathon Running ◽  
Internal Dimension ◽  
Cardiac Fatigue ◽  
Change In Mean

We assessed segmental and global left ventricular (LV) systolic function using tissue Doppler imaging (TDI) in 30 subjects (age: 18-62 y) before and after a marathon race. Longitudinal plane systolic (S′) TDI velocities were assessed at 5 sites on the mitral annulus and radial plane S' velocities were assessed at the LV septal and free wall in a subsample (n = 9). Heart rate (HR) and LV diastolic internal dimension were also assessed before (pre) and immediately after (post) the race. Pre-post changes in all variables were analysed by repeated measures analysis of variance (ANOVA). Delta scores for TDI data were correlated with alterations in indices of LV loading, as well as with age and finishing time. Segmental longitudinal and radial TDI velocities were not significantly different pre to post race (p > 0.05), which resulted in no change in mean S′ velocities (longitudinal: pre 17.0 ± 3.4 cm·s-1, post 17.4 ± 4.0 cm·s-1; radial: pre 13.0 ± 5.4 cm·s-1, post 14.2 ± 7.1 cm·s-1; p > 0.05). Any pre-post changes in TDI data were not related to an elevated post race HR (r = 0.15, p > 0.05), a decreased post race LV internal dimension in diastole (r = 0.10, p > 0.05), age (r = -0.25, p > 0.05), or finishing time (r = -0.13, p > 0.05). Our data suggest that marathon running does not induce any segmental or global depression in LV systolic function.Key words: tissue Doppler imaging, cardiac fatigue, echocardiography, marathon.

Abstract 15719: Right Ventricular Dysfunction After Transcatheter Aortic Valve Replacement (TAVR)

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Saki Ito ◽  
Sorin V Pislaru ◽  
Vuyisile T Nkomo ◽  
Jae K Oh ◽  
Kevin L Greason ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Right Ventricular ◽  
Valve Replacement ◽  
Transcatheter Aortic Valve Replacement ◽  
Systolic Function ◽  
Aortic Valve Area ◽  
Transcatheter Aortic Valve ◽  
The Impact ◽  
Rv Function

Background: Transcatheter aortic valve replacement (TAVR) is an alternative to surgical aortic valve replacement in patients at high surgical risk. We investigated the impact of TAVR on left (LV) and right ventricular (RV) function using conventional echocardiography parameters. Methods and results: A total of 202 consecutive patients (age 80.6±8.0 years, aortic valve area 0.80±0.16cm 2 ) who underwent TAVR at Mayo Clinic between 2008 and 2013 were included in the study. LV ejection fraction (EF) and RV systolic function including tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC) and, systolic excursion velocity (S’) were compared before (median 33.5 days) and after TAVR procedure (median 30 days). Patients who underwent pacemaker implantation after TAVR were excluded. LV EF significantly improved following TAVR (55.3±12.6% pre vs 58.5±11.1% post; p<0.05). In contrast, RV systolic function significantly decreased after TAVR (pre vs post; TAPSE: 18.8±6.3 mm vs 17.4±6.3 mm, FAC: 42.6±9.8% vs 37.3±8.2%; S’: 10.7±2.6 cm/s vs 10.2±2.6 cm/s; p<0.05 for all). Stratifying RV functional change by TAVR approach site, patients undergoing trans-femoral TAVR (n=100) showed RV deterioration only by FAC (see Table). In contrast, RV systolic dysfunction was more prominent in trans-apical approach group (n=87) with significant decline in all parameters of RV systolic function (see Table). Conclusion: TAVR is associated with early enhancement in LV systolic function. However, there is evidence of worsening RV function in a significant number of patients. Further studies are necessary to determine whether this deterioration in RV function is related to anatomic access site or to other factors, and to evaluate its prognostic significance.

scholarly journals The impact of right ventricular pressure and function on survival in patients with pulmonary vein stenosis

2018 ◽  
Vol 8 (2) ◽  
pp. 204589401877689 ◽  
Author(s):  
Michelle C. Sykes ◽  
Christina Ireland ◽  
Julia E. McSweeney ◽  
Emily Rosenholm ◽  
Kristofer G. Andren ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Pulmonary Vein ◽  
Cardiac Catheterization ◽  
Systolic Function ◽  
Balloon Dilation ◽  
Pulmonary Vein Stenosis ◽  
Pulmonary Hemodynamics ◽  
Vein Stenosis ◽  
The Impact ◽  
Rv Function

Pulmonary vein stenosis (PVS) is associated with pulmonary hypertension (PH), but there is little information regarding the impact of PH on right ventricular (RV) systolic function and survival. We conducted a retrospective cohort study of our patients to explore this and other aspects of pulmonary hemodynamics with PVS. RV function was assessed using qualitative two-dimensional echocardiography. The ratio of systolic pulmonary artery (PA) and aortic pressures (PA:Ao) at cardiac catheterization reflected pulmonary hemodynamics. Reactivity testing employed inhaled nitric oxide + 100% fiO2, or 100% fiO2 only; “reactivity” was a ≥ 20% decrease in PA:Ao. There were 105 PVS patients, although not all had data at every time point. (1) The mean PA:Ao at first cardiac catheterization (n = 77) was 0.79 ± 0.36; at last catheterization (n = 54), PA:Ao = 0.69 ± 0.30; 90% had systolic PAP > one-half systemic. Survival was shorter with PA:Ao > 0.5. (2) Differences in survival relative to RV dysfunction on the first echocardiogram were not significant, although they were using the last echocardiogram. (3) The magnitude of RV dysfunction was positively correlated with PA:Ao. (4) Balloon dilation of PV acutely decreased PA:Ao (–0.13 ± 0.37, P = 0.03 [n = 40 patients]). 5. Of 20 patients tested, 13 were acutely reactive to vasodilators. PH is a major feature of PVS. Reduced RV function and PA:Ao appear to be predictors of survival. Given the importance of PH in this disease, clinical studies of PVS treatments should include measures of PAP and RV function as important variables of interest.

scholarly journals The impact of marathon running on atrial remodeling in male and female amateur athletes assessed by three-dimensional echocardiography

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
Z.B Lasocka ◽  
A Dabrowska-Kugacka ◽  
A Kaleta-Duss ◽  
Z Lewicka-Potocka ◽  
A Faran ◽  
...  
Keyword(s):  
Three Dimensional ◽  
3D Echocardiography ◽  
Marathon Running ◽  
Atrial Remodeling ◽  
Male And Female ◽  
Amateur Athletes ◽  
Exercise Induced ◽  
And Function ◽  
Stage 1 ◽  
The Impact

Abstract Introduction Endurance athletes have an increased risk of atrial remodeling and atrial arrhythmias. However, data regarding atrial adaptation to physical exercise in non-elite athletes are limited. We aimed to assess exercise-induced alternations in atrial morphology and function in male and female amateur marathon runners, using real-time three-dimensional (3D) echocardiography. Methods The study group consisted of 40 male (39±8 years) and 27 female (40±7 years) amateur athletes. 3D echocardiography was performed 2–3 weeks before (Stage 1) and immediately after (Stage 2) the marathon run. Right (RA) and left atrial (LA) remodeling was assessed by volumetric measures, total ejection fraction (EF) and volume (EV). Speckle tracking was used to determine the temporal evaluation of atrial function by strain analysis. Results The main results are presented in Table 1. At rest, male athletes demonstrated greater RA size and decreased RA contractility, as assessed by EF and atrial strains, in comparison to females. At Stage 1, LA morphology and function did not differ significantly between genders. After the marathon, a remarkable increase in RA maximal volume (RAVmax, 32.9±8.6 vs. 36.4±8.2 ml/m2, p=0.016) and RAEF (49.5±9.7 vs. 57.3±9.2%, p=0.002) was observed only in female athletes (p&lt;0.05 for both interactions sex and stage). Whereas in male runners, LA measures, such as LAVmax (30.7±6.4 vs. 26.8±6.2 ml/m2, p=0.007), LAEF (56.7±4.3 vs. 52.7±5.3%, p=0.037) and LA conduit strain (LAScd, −18.7±8 vs. −13.6±8%, p=0.045), significantly decreased postrace. This observation was absent in females (p&lt;0.05 for all interactions sex and stage). Conclusions In amateur athletes, marathon running promotes biatrial remodelling with significant gender discrepancies. Females are more susceptible to exercise-induced morphological and functional changes of RA, while postrace alternations in males concern principally LA. 3D echocardiography of the atria is a useful indicator of exercise capacity, not only in elite, but also in amateur athletes. FUNDunding Acknowledgement Type of funding sources: None.

Multidisciplinary team decision is rare and decreasing in percutaneous vascular interventions despite positive impact on in-hospital outcomes

VASA ◽  
2019 ◽  
Vol 48 (3) ◽  
pp. 262-269 ◽  
Author(s):  
Christian-Alexander Behrendt ◽  
Tilo Kölbel ◽  
Thea Schwaneberg ◽  
Holger Diener ◽  
Ralf Hohnhold ◽  
...  
Keyword(s):  
Multidisciplinary Team ◽  
Positive Impact ◽  
Cross Sectional Study ◽  
Invasive Treatment ◽  
Cross Sectional ◽  
Hospital Outcomes ◽  
Vascular Intervention ◽  
Medical Specialties ◽  
Team Decision ◽  
The Impact

Abstract. Background: Worldwide prevalence of peripheral artery disease (PAD) is increasing and peripheral vascular intervention (PVI) has become the primary invasive treatment. There is evidence that multidisciplinary team decision-making (MTD) has an impact on in-hospital outcomes. This study aims to depict practice patterns and time changes regarding MTD of different medical specialties. Methods: This is a retrospective cross-sectional study design. 20,748 invasive, percutaneous PVI of PAD conducted in the metropolitan area of Hamburg (Germany) were consecutively collected between January 2004 and December 2014. Results: MTD prior to PVI was associated with lower odds of early unsuccessful termination of the procedures (Odds Ratio 0.662, p < 0.001). The proportion of MTD decreased over the study period (30.9 % until 2009 vs. 16.6 % from 2010, p < 0.001) while rates of critical limb-threatening ischemia (34.5 % vs. 42.1 %), patients´ age (70 vs. 72 years), PVI below-the-knee (BTK) (13.2 % vs. 22.4 %), and rates of severe TASC C/D lesions BTK (43.2 % vs. 54.2 %) increased (all p < 0.001). Utilization of MTD was different between medical specialties with lowest frequency in procedures performed by internists when compared to other medical specialties (7.1 % vs. 25.7 %, p < 0.001). Conclusions: MTD prior to PVI is associated with technical success of the procedure. Nonetheless, rates of MTD prior to PVI are decreasing during the study period. Future studies should address the impact of multidisciplinary vascular teams on long-term outcomes.

Impact of external currency exposures on macroeconomic policies

2020 ◽  
pp. 23-40
Author(s):  
I. V. Prilepskiy
Keyword(s):  
Monetary Policy ◽  
Exchange Rate ◽  
Positive Impact ◽  
Exchange Rate Regime ◽  
Macroeconomic Policies ◽  
Panel Regressions ◽  
Financial Account ◽  
Currency Exposure ◽  
Cross Country ◽  
The Impact

Based on cross-country panel regressions, the paper analyzes the impact of external currency exposures on monetary policy, exchange rate regime and capital controls. It is determined that positive net external position (which, e.g., is the case for Russia) is associated with a higher degree of monetary policy autonomy, i.e. the national key interest rate is less responsive to Fed/ECB policy and exchange rate fluctuations. Therefore, the risks of cross-country synchronization of financial cycles are reduced, while central banks are able to place a larger emphasis on their price stability mandates. Significant positive impact of net external currency exposure on exchange rate flexibility and financial account liberalization is only found in the context of static models. This is probably due to the two-way links between incentives for external assets/liabilities accumulation and these macroeconomic policy tools.

Evaluation of the impact of public investment programs on social and economic performance of territories

2019 ◽  
pp. 109-123
Author(s):  
I. E. Limonov ◽  
M. V. Nesena
Keyword(s):  
Bayesian Modeling ◽  
Positive Impact ◽  
Public Investment ◽  
Difference In Differences ◽  
The Public ◽  
Export Activity ◽  
Regional Investment ◽  
The Difference ◽  
The Impact ◽  
Development Institution

The purpose of this study is to evaluate the impact of public investment programs on the socio-economic development of territories. As a case, the federal target programs for the development of regions and investment programs of the financial development institution — Vnesheconombank, designed to solve the problems of regional development are considered. The impact of the public interventions were evaluated by the “difference in differences” method using Bayesian modeling. The results of the evaluation suggest the positive impact of federal target programs on the total factor productivity of regions and on innovation; and that regional investment programs of Vnesheconombank are improving the export activity. All of the investments considered are likely to have contributed to the reduction of unemployment, but their implementation has been accompanied by an increase in social inequality.

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