scholarly journals Bacterial profile and drug susceptibility pattern of urinary tract infection in pregnant women at University of Gondar Teaching Hospital, Northwest Ethiopia

2012 ◽  
Vol 5 (1) ◽  
Author(s):  
Agersew Alemu ◽  
Feleke Moges ◽  
Yitayal Shiferaw ◽  
Ketema Tafess ◽  
Afework Kassu ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Teaching Hospital ◽  
Drug Susceptibility ◽  
Northwest Ethiopia ◽  
Susceptibility Pattern ◽  
Drug Susceptibility Pattern

scholarly journals Bacterial profile, antibiotic susceptibility pattern and associated risk factors of urinary tract infection among clinically suspected children attending at Felege-Hiwot Comprehensive and Specialized Hospital, Northwest Ethiopia. A prospective study

2020 ◽  
Author(s):  
Adugna Fenta ◽  
Mulat Dagnew ◽  
Setegn Eshetie ◽  
Teshome Belachew
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antimicrobial Susceptibility ◽  
Northwest Ethiopia ◽  
Bacterial Isolates ◽  
Susceptibility Pattern ◽  
Gram Negative ◽  
Antimicrobial Susceptibility Pattern ◽  
Specialized Hospital

Abstract Background: Urinary tract infection is one of the most common bacterial infections in children. Understanding the characteristics of uropathogens and their antimicrobial susceptibility pattern in a particular setting can provide evidence for the appropriate management of cases. This study aimed to assess the bacterial profile of urinary tract infection, their antimicrobial susceptibility pattern and associated factors among clinically suspected children attending at Felege-Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia.Methods: A hospital-based cross-sectional study was conducted from February-April, 2019. A systematic sampling technique was employed. A mid-stream urine sample was inoculated on cystine lactose electrolyte deficient media and incubated for 24-48 hours. Sub-culturing was done on Mac-Conkey and blood agar. Antimicrobial susceptibility test was done on Muller-Hinton agar. A binary logistic regression model was used to see the association between dependent and independent factors. A p-value<0.05 at 95% CI was considered as statistically significant.Results: The overall prevalence of urinary tract infection was 16.7% (95% CI 12.4-21.1). Both Gram-negative and Gram-positive bacterial isolates were recovered with a rate of 44/50 (88%) and 6/50 (12%) respectively. Among Gram-negative isolates, E. coli 28/44(63.6%) was predominant while S. saprophyticus 2/6(33.3%) was prevalent among Gram-positive bacterial isolates. Overall, a high level of resistance to ampicillin, augmentin, and tetracycline was shown by Gram-negative bacteria with a rate of 44/44(100%), 39/44(88.6%), and36/44 (81.8%) respectively. About 33/50(66%) of overall multidrug resistance was observed (95% CI 52-78). About six Gram-negative bacterial isolates were extended spectrum beta-lactamase (ESBL) producers. Having a history of urinary tract infection (P-0.003, AOR 1.86-22.15) and male uncircumcision (p-0.00, AOR 5.5-65.35) were the independent variables that associate for urinary tract infections.Conclusion: In the present study, the prevalence of urinary tract infection among children was high and considerably a high proportion of multidrug resistance was observed. This result will have a significant impact on the selection of appropriate antimicrobial agents for the treatment of urinary tract infection.

scholarly journals Urinary Tract Infection and Drug Susceptibility Pattern in Patients of a Medical College Hospital in Bangladesh

2014 ◽  
Vol 4 (1) ◽  
pp. 21-25
Author(s):  
Rafiul Alam Khan ◽  
Md Fazhul Karim
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Drug Susceptibility ◽  
Susceptibility Pattern ◽  
Isolation And Identification ◽  
College Hospital ◽  
Klebsiella Species ◽  
Medical College ◽  
Single Organism

Background: Urinary tract infection (UTI) is a common and frequently encountered serious morbidity that afflicts the tool not only to all segments of human population but also results in increasing antibiotic resistance due to persistence and mismanagement of the ailment. The present study aimed to ascertain the current situation of antimicrobial resistance of urinary tract infection. Objectives: To find out pyuria by direct microscopy, isolation and identification of the organisms by culture and to know the susceptibility pattern of organisms causing urinary tract infection. Materials and Methods: A total of 180 midstream urine samples were subjected to aerobic bacteriologic culture in the department of Microbiology, Cox’s Bazar Medical College and 250-bedded Sadar Hospital, Cox’s Bazar during the period of March to October 2012. Specimens were collected from hospitalized and outdoor patients of different age and sex groups. All specimens were examined by routine microscopy to find out significant pyuria (>5 pus cells/HPF). Strict aseptic precautions were taken all through the culture system. Results: Out of 180 specimens, 101 (56.11%) culture yielded significant growth of single organism and 79 (43.89%) yielded no growth. The isolated organisms were E. coli 74.26%, Klebsiella species 12.87%, Enterococci 4.95%, Staphylococcus saprophyticus 3.96%, Pseudomonas species 1.98% and Proteus species 1.98%. The highest sensitivity was shown by imipenem (100%) followed by ceftriaxone (65%), azithromycin (65%), ciprofloxacin (60%) and less sensitive to amoxycillin, cotrimoxazole, cephradine and nalidixic acid ranging 15–30%. Conclusion: The findings of the present study recommends that UTI should be treated by selective antibiotics obtained from culture and sensitivity test to minimize increasing trend of drug resistance. DOI: http://dx.doi.org/10.3329/jemc.v4i1.18064 J Enam Med Col 2014; 4(1): 21-25

scholarly journals Drug Susceptibility Pattern and Associated Factors of Bacteria Isolated from Urinary Tract Infection among Pregnant Women Attending Antenatal Care in Teaching Hospital, Southeast Ethiopia

2021 ◽  
Author(s):  
Eshetu Nigussie ◽  
Meseret Mitiku ◽  
Alelign Tasew ◽  
Biniyam sahiledengel ◽  
Damtew Solomon ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Previous History ◽  
Urine Samples ◽  
P Value ◽  
Susceptibility Pattern ◽  
Southeast Ethiopia ◽  
Significant Bacteriuria

Abstract Background: Urinary tract infection is caused by bacteria from the digestive tract which climbs the opening of the urethra and begins to multiply to cause infection. This study aimed to assess the bacterial profile and antibiotic susceptibility pattern and associated risk factors among pregnant women in Madda Walabu University Goba Referral Hospital, Southeast Ethiopia. Methods: An institution-based cross-sectional study was conducted from June-August, 2019. A total of 234 pregnant women were enrolled; data were collected using a structured questionnaire by a trained interviewer. Urine samples were collected from all pregnant women and culture on cysteine lysine electrolytes deficiency medium. Data were analyzed using SPSS 20.0. Descriptive statistics were used to explain the study participants with relevant variables. Logistic regression was used for data comparison. P-value <0.05 was accepted as statistically significant. Results: The overall prevalence of UTI was 23.9% among both asymptomatic and symptomatic groups. Of this screened midstream urine samples showed that 16% and 32.2%, had significant bacteriuria in the asymptomatic and symptomatic groups respectively. The prevalence of UTI was significantly associated with previous history of catheterization and urinary tract infection. E. coli was the most frequently isolated organism (42.9%) followed by coagulase-negative Staphylococcus (26.8%), and S. aureus (12.5%). Gram-negative and Gram-positive bacteria accounted for (59%) and (41%) respectively.Conclusion: Significant bacteriuria has been observed from both symptomatic and asymptomatic pregnant women. The majority of the isolates were resistant to commonly prescribed antibiotics. This calls for an early screening of all pregnant women for UTI and those found to be infected need treatment.

scholarly journals Etiology and prevalence of urinary tract infections among pregnant women in Kerala

2018 ◽  
Vol 5 (8) ◽  
pp. 3298
Author(s):  
Srinath M. P. ◽  
Shajina M. ◽  
Fasalu Rahiman O. M.
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Drug Susceptibility ◽  
Premature Delivery ◽  
Fetal Mortality ◽  
Microbiological Analysis ◽  
Tract Infections ◽  
In Pregnancy

Background: Infectious disease such as urinary tract infection was found very commonly during all pregnancies. Chronic renal failure, pyelonephritis, preeclampsia, anemia, fetal mortality and premature delivery are the common complication associated with UTI in pregnancy. Hence the management and prevention of UTI in pregnancy is the crucial factor for the sustained pregnant period. It is more important for a clinician to recognize the pathogenic factor for UTI and its sensitivity profile for planning an effective treatment for infected patients. Hence the present study was designed to identify the pathogenic agents of UTI among pregnant women and to find out the drug susceptibility patterns of the isolated organism against commonly prescribed antibioticsMethods: A prospective analysis was carried out by collecting urine from the 210 patients, the sample was also processed for antimicrobial drug susceptibility testing.Results: A positive report was seen in 26 cases with 13.4% of incident rate. Escherichia coli 14 (53.8%), Klebsiella species 23.07%, Enterococcus species 7.69%, Staphylococcus aureus 3.84%, Proteus 3.84%, Pseudomonas aeroginosa 3.84%, Streptococcus pyogenes 3.84% were the most common isolate found in the present population. The isolated pathogens were sensitive to Ceftazidime, Cefotaxime, Ciprofloxacin, Gentamicin, and Amikacin.Conclusions: It is there for recommended that routine microbiological analysis and antibiotic sensitivity test of urine samples of pregnant women must be carried out before the administration of drugs for better treatments and managements of urinary tract infection.

scholarly journals Prevalence and Susceptibility Pattern of Bacterial Uropathogens among Patients with Urinary Tract Infection at Birat Medical College Teaching Hospital of Eastern Nepal

2020 ◽  
Vol 5 (2) ◽  
pp. 1011-1015
Author(s):  
Bijoylakshmi Dewasy ◽  
Randhir Kumar Singh ◽  
Surya Bahadur Parajuli ◽  
Tara Kafle ◽  
Anjali Mishra
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Nalidixic Acid ◽  
Teaching Hospital ◽  
Urine Culture ◽  
College Teaching ◽  
Susceptibility Pattern ◽  
Medical College ◽  
Klebsiella Spp

Introduction Urinary tract infection (UTI) is a frequent condition encountered in clinical settings. Empirical treatment is common. The treatment without urine culture and sensitivity leads to antimicrobial resistance. This is a major global concern. Objective The objective of this study was to find the prevalence and susceptibility pattern of Bacterial Uropathogens among patients with Urinary Tract Infection at Birat Medical College and Teaching Hospital of eastern Nepal. Methodology A cross-sectional study was conducted among patients with UTI attending Birat Medical College and Teaching Hospital from August 2018 to December 2018. The sample size of the study was 530. Ethical clearance was taken from the Institutional Review Committee of Birat Medical College and Teaching Hospital (Ref: IRC-PA-009/2075-76). Data were entered into Microsoft Excel and analyzed by using SPSS. Results The prevalence of bacterial uropathogens among urine culture was 66.04%. The common uropathogens isolated were E.coli (66.9%) and Klebsiella spp (15.1%). E.coli was highly susceptible to Chloramphenicol (100%) followed by Ceftrixone (82.4%), Cefpodoxime (77.8%) and Amikacin (77.9%); while Klebsiella spp were susceptible to nalidixic acid (40%) followed by co-trimoxazole (17.9%). Conclusion Almost 2 out of 3 samples had bacterial uropathogens isolated. E. coli and Klebsiella spp were common. Chloramphenicol and Nalidixic acid were highly susceptible to E.coli and Klebsiella spp respectively.

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