scholarly journals Urinary Tract Infection and Drug Susceptibility Pattern in Patients of a Medical College Hospital in Bangladesh

2014 ◽  
Vol 4 (1) ◽  
pp. 21-25
Author(s):  
Rafiul Alam Khan ◽  
Md Fazhul Karim
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Drug Susceptibility ◽  
Susceptibility Pattern ◽  
Isolation And Identification ◽  
College Hospital ◽  
Klebsiella Species ◽  
Medical College ◽  
Single Organism

Background: Urinary tract infection (UTI) is a common and frequently encountered serious morbidity that afflicts the tool not only to all segments of human population but also results in increasing antibiotic resistance due to persistence and mismanagement of the ailment. The present study aimed to ascertain the current situation of antimicrobial resistance of urinary tract infection. Objectives: To find out pyuria by direct microscopy, isolation and identification of the organisms by culture and to know the susceptibility pattern of organisms causing urinary tract infection. Materials and Methods: A total of 180 midstream urine samples were subjected to aerobic bacteriologic culture in the department of Microbiology, Cox’s Bazar Medical College and 250-bedded Sadar Hospital, Cox’s Bazar during the period of March to October 2012. Specimens were collected from hospitalized and outdoor patients of different age and sex groups. All specimens were examined by routine microscopy to find out significant pyuria (>5 pus cells/HPF). Strict aseptic precautions were taken all through the culture system. Results: Out of 180 specimens, 101 (56.11%) culture yielded significant growth of single organism and 79 (43.89%) yielded no growth. The isolated organisms were E. coli 74.26%, Klebsiella species 12.87%, Enterococci 4.95%, Staphylococcus saprophyticus 3.96%, Pseudomonas species 1.98% and Proteus species 1.98%. The highest sensitivity was shown by imipenem (100%) followed by ceftriaxone (65%), azithromycin (65%), ciprofloxacin (60%) and less sensitive to amoxycillin, cotrimoxazole, cephradine and nalidixic acid ranging 15–30%. Conclusion: The findings of the present study recommends that UTI should be treated by selective antibiotics obtained from culture and sensitivity test to minimize increasing trend of drug resistance. DOI: http://dx.doi.org/10.3329/jemc.v4i1.18064 J Enam Med Col 2014; 4(1): 21-25

scholarly journals Isolation and Antimicrobial Susceptibility Pattern of Escherichia coli Causing Urinary Tract Infection in Enam Medical College Hospital

2012 ◽  
Vol 1 (2) ◽  
pp. 60-62 ◽  
Author(s):  
Mejbah Uddin Ahmed ◽  
Md Khairuzzaman ◽  
Afroza Begum ◽  
Iftikhar Ahmed
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Antimicrobial Resistance ◽  
Tract Infection ◽  
Resistance Pattern ◽  
Susceptibility Pattern ◽  
College Hospital ◽  
Medical College ◽  
Antimicrobial Susceptibility Pattern

Background: Since antibiotic resistance of uropathogens has gradually been rising, knowledge of antimicrobial resistance pattern of Escherichia coli (Esch. coli), the predominant  pathogen of urinary tract infection (UTI), is important in selecting empirical antimicrobial  therapy.Objectives: To find out the common organisms causing UTI with their antimicrobial  susceptibility pattern in Enam Medical College Hospital.Materials and Methods: This study  was carried out in the department of Microbiology, Enam Medical College Hospital, Savar,  Dhaka between January 2010 to June 2011 to see the antimicrobial resistance pattern of Esch.  coli in urine sample. A total of 512 urine samples were studied from clinically suspected UTI  cases irrespective of age and sex. Esch. coli were isolated and antibiogram of the isolates were  done.Results: The results of antibiogram revealed the resistance pattern of the isolated Esch. coli to ampicillin (93.94%), cefradine (70.71%), trimethoprim-sulfamethoxazole (48.49%),  azithromycin (41.42%), ciprofloxacin (39.40%), ceftazidime (35.56%), nitrofurantoin  (29.30%), ceftriaxone (10.11%), gentamicin (7.08%) and imipenem (3.04%).Conclusion: It  can be inferred that our findings will render useful information to clinicians in determining the  appropriately directed antimicrobial regimen when given empirically. DOI: http://dx.doi.org/10.3329/jemc.v1i2.11463 J Enam Med Col 2011; 1(2): 60-62

Detection of Virulence Factors and Antimicrobial Resistance in Enterococci Isolated from Urinary Tract Infection

2018 ◽  
Vol 4 (2) ◽  
pp. 30-34 ◽  
Author(s):  
Surovi Era Suchi ◽  
SM Shamsuzzaman ◽  
Bhuiyan Mohammad Mahtab Uddin ◽  
Md Abdullah Yusuf
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antimicrobial Susceptibility ◽  
Virulence Genes ◽  
Diffusion Method ◽  
Susceptibility Pattern ◽  
Disk Diffusion Method ◽  
Cross Sectional ◽  
Medical College

Background: The genus Enterococcus is of increasing significance as a cause of nosocomial infections and this trend is exacerbated by the development of antibiotic resistance.Objective: The aims of this study was to find out the susceptibility pattern and the prevalence of virulence genes in Enterococcus strains isolated from urinary tract infection in Bangladesh.Methodology: This cross-sectional study was conducted in the Department of Microbiology at Dhaka Medical College, Dhaka from January 2015 to December 2015 for a period of one (01) years. All the admitted patients in the Dhaka Medical College & Hospital, Dhaka and Banghabandhu Sheikh Mujib Medical University, Dhaka who were  presented with clinical features of urinary tract infection at any age with both sexes were included as study population. The antimicrobial susceptibility of the strains was determined using the disk diffusion method; vancomycin susceptibility pattern was detected by MIC method. PCR was performed for the detection of genus-species, vanA, vanB gene and potential virulence genes.Result: Out of 84 Enterococci, majority (71.42%) of the isolates were E. faecalis followed by 23.81% were E. faecium. Regarding antimicrobial susceptibility pattern, 100% isolated Enterococci were sensitive to vancomycin, linezolid and teicoplanin. Most of the Enterococci were resistant to ciprofloxacin and ceftriaxone (92.86%) followed by 88.10% to gentamicin and 85.71% to azithromycin and rifampicin. No VRE was identified and the range of MIC for vancomycin was 1-4 µg/ml. None of the Enterococci was positive for vanA and vanB genes. Out of total E. faecalis and E. faecium, 87.50% were positive for ebp and 77.5%, 72.5%, 55.0%, 45.0%, 40.0% and 10.0% of isolates were positive for gelE, esp, ace, cyl, asa and hyl respectively.Conclusion: Almost all the virulence genes were more prevalent in E. faecalis isolates.Bangladesh Journal of Infectious Diseases 2017;4(2):30-34

scholarly journals PREVALENCE OF URINARY TRACT INFECTION IN CHILDREN (AGE 1 MONTH TO 5 YEARS) WITH FEVER ADMITTED IN JHALAWAR MEDICAL COLLEGE, JHALAWAR

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Rakesh Kumar Sharma ◽  
Kapil Kumar ◽  
Anita Devi
Keyword(s):  
Urinary Tract Infection ◽  
Preschool Children ◽  
Urinary Tract ◽  
Tract Infection ◽  
Tertiary Care ◽  
Tertiary Care Centre ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Culture Positive

Background: The present study is undertaken to estimate the prevalence of urinary tract infection in febrile preschool children (1 month to 5 years of age) in febrile children visiting at tertiary care centre of Jhalawar, Rajasthan Methods: It was a cross-sectional, prospective, observational, non interventional study, carried out to analyse the prevalence of urinary tract infection in febrile preschool children (1 month to 5 years of age) in febrile children visiting medical college, Hospital Jhalawar. The study was conducted in Department of Paediatrics, between Dec. 2019  to  March 2020. The study was approved by Ethics Committee.   Results: During the study period, we have screened total 1379 preschool children (under 5 years of age) with fever. Out of this total 1379 febrile children, 86 children found to be culture positive cases for UTI (CP-UTI). The prevalence of culture positive cases for UTI in this study was 6.23%. In the prospect of age, 24 (27.91%) children were found to be infant and 62(72.09%) children were found to be of age between 1 years to 5 years. Conclusion: UTIs in preschool children are often having vague and variable symptoms, often fever is the only symptoms. An untreated UTI can lead to subsequent damage and impairment of renal structure and function, it is very important to diagnose and treat UTI in preschool children. Keywords: Urinary tract infection, E.coli, Fever.

scholarly journals Prevalence and Susceptibility Pattern of Bacterial Uropathogens among Patients with Urinary Tract Infection at Birat Medical College Teaching Hospital of Eastern Nepal

2020 ◽  
Vol 5 (2) ◽  
pp. 1011-1015
Author(s):  
Bijoylakshmi Dewasy ◽  
Randhir Kumar Singh ◽  
Surya Bahadur Parajuli ◽  
Tara Kafle ◽  
Anjali Mishra
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Nalidixic Acid ◽  
Teaching Hospital ◽  
Urine Culture ◽  
College Teaching ◽  
Susceptibility Pattern ◽  
Medical College ◽  
Klebsiella Spp

Introduction Urinary tract infection (UTI) is a frequent condition encountered in clinical settings. Empirical treatment is common. The treatment without urine culture and sensitivity leads to antimicrobial resistance. This is a major global concern. Objective The objective of this study was to find the prevalence and susceptibility pattern of Bacterial Uropathogens among patients with Urinary Tract Infection at Birat Medical College and Teaching Hospital of eastern Nepal. Methodology A cross-sectional study was conducted among patients with UTI attending Birat Medical College and Teaching Hospital from August 2018 to December 2018. The sample size of the study was 530. Ethical clearance was taken from the Institutional Review Committee of Birat Medical College and Teaching Hospital (Ref: IRC-PA-009/2075-76). Data were entered into Microsoft Excel and analyzed by using SPSS. Results The prevalence of bacterial uropathogens among urine culture was 66.04%. The common uropathogens isolated were E.coli (66.9%) and Klebsiella spp (15.1%). E.coli was highly susceptible to Chloramphenicol (100%) followed by Ceftrixone (82.4%), Cefpodoxime (77.8%) and Amikacin (77.9%); while Klebsiella spp were susceptible to nalidixic acid (40%) followed by co-trimoxazole (17.9%). Conclusion Almost 2 out of 3 samples had bacterial uropathogens isolated. E. coli and Klebsiella spp were common. Chloramphenicol and Nalidixic acid were highly susceptible to E.coli and Klebsiella spp respectively.

scholarly journals Antibiotic resistance pattern of bacteria causing urinary tract infection in a private medical college hospital, Dhaka

2017 ◽  
Vol 16 (1) ◽  
pp. 42-47
Author(s):  
Mahmuda Siddiqua ◽  
Ahmed Nawsher Alam ◽  
Sonia Akter ◽  
Reena Saad Ferdousi
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Medical College Hospital ◽  
Resistance Pattern ◽  
College Hospital ◽  
E Coli ◽  
Medical College ◽  
Tract Infections ◽  
Resistance Rates

Background and objective: Urinary tract infection (UTI) is one of the frequently seen infections both in the world and in our country as well. Escherichia coli (E. coli) aremost frequently isolated in complicated or uncomplicated, nosocomial or community acquired urinary tract infections. To guide the empirical therapy, the resistance pattern of E. coli responsible was evaluated throughout the period in this study.Material and Method: Urine samples from outpatient / inpatient department of Ibn Sina Medical College Hospital between 1st January, 2015 and 31st December, 2015 were retrospectively analyzed. Presence of ?105 colony forming units/ml in urine culture was considered as significant for UTI. Isolated bacteria were identified by standard laboratory techniques and antibiotic susceptibility testing was performed by Kirby-Bauer disk diffusion method using Clinical Laboratory Standard Institute (CLSI) criteria.Result: A total of 271(13.4%) uropathogens were isolated. Overall E. coli accounted for 180 (66.42%) of all isolates. Resistance rates of E. coli to antimicrobial agents was demonstrated to be as follows: cefuroxime 82%, nalidaxic acid 74%, azithromycin 56%, cefotaxime52%, ceftazidime50%, cefixime 47%, cotrimoxazole 43%, ceftriaxone 41%, ciprofloxacin38%, amoxicillin- clavulanic acid 31%, cefepime30%, and low resistance which ranges from 9 to 1% included gentamycin 9%, meropenem 3%, imipenem2%, nitrofurantoin2% and amikacin 1%.Conclusion: As resistance rates show regional differences, it is necessary to regularly monitor regional resistance pattern to determine the appropriate empiric antibiotic treatment. The national antibiotic usage policies must be reorganized according to data obtained from these studies.Bangladesh Journal of Medical Science Vol.16(1) 2017 p.42-47

scholarly journals Short term catheterization versus long term catheterization after vaginal prolapsed surgery: A randomized control trial in Dhaka National Medical College & Hospital

2013 ◽  
Vol 18 (2) ◽  
pp. 4-8
Author(s):  
Mst Hosna Ara Khatun ◽  
Jahanara Arzu ◽  
Zulfe Ara Haider
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Residual Volume ◽  
Short Term ◽  
College Hospital ◽  
National Medical College ◽  
Medical College ◽  
National Medical

Objective: This study was undertaken to determine whether short term bladder catheterization would be more beneficial than the routinely practiced long term catheterization after vaginal hysterectomy for prolapsed uterus.  Materials and methods: This randomized controlled trial was conducted in Obstetrics and Gynecology Department of Dhaka National Medical College Hospital from January 2009 to January 2011. A total of 106 women were included in this study. They were randomized into short term catheterization group where transurethral catheter was removed after 24 hours of surgery and long term catheterization group where catheter was removed on 3rd post operative day.  Result: Mean time of first voiding after removal of catheter was almost equal in both groups (2.82±1.42 hours and 2.74±1.52 hours). Duration of catheter did not affect the duration of first voiding time after removal of catheter (P>0.05). None of the women had residual volume of urine >200 ml in both groups. Mean residual volume is significantly high in long term catheterization group (P<0.05). Urinary tract infection was also significantly high in long term catheterization group (P<0.05) and majority of the infection were caused by E. coli.  Conclusion: Short term catheterization is more beneficial in terms of lower incidence of urinary tract infection and prevention of bladder over filling as compared to long term catheterization after vaginal prolapsed surgery. DOI: http://dx.doi.org/10.3329/jdnmch.v18i2.16012 J. Dhaka National Med. Coll. Hos. 2012; 18 (02): 4-8

scholarly journals Bacteriology of urinary tract infection in pediatric patients at KIST Medical College Teaching Hospital

2014 ◽  
Vol 3 (1) ◽  
pp. 21-25 ◽  
Author(s):  
Birendra Raj Raghubanshi ◽  
Devendra Shrestha ◽  
Mahesh Chaudhary ◽  
Bal Man Singh Karki ◽  
Ajaya Kumar Dhakal
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antimicrobial Susceptibility ◽  
Demographic Data ◽  
College Teaching ◽  
Susceptibility Pattern ◽  
Medical College ◽  
Antimicrobial Susceptibility Pattern

Background: Urinary tract infection is common in children and is an important cause of morbidity. Urinary tract infection at young age can lead to renal injury and scarring, and ultimately lead to end stage renal disease in adulthood. Objectives: The purpose of study was to identify the different species of microorganisms, along with their antimicrobial susceptibility pattern, causing urinary tract infection in paediatric patients presenting with urinary tract infection at KIST Medical College, Imadol, Lalitpur, Nepal. Methods: This retrospective study examined microbiological and antimicrobial susceptibility pattern for urine samples collected at KIST Medical College, Imadol, Lalitpur from December 2010 to November 2013. A urine sample was included in our dataset if it demonstrated pure growth of a single organism and accompanying antimicrobial susceptibility and subject demographic data were available. Results: Escherichia coli was the most common organism isolated, followed by Klebsiella species, Staphylococcus species and then by Proteus species, Enterococcus species and Citrobacter species being equal in number. Microorganisms were most susceptible to amikacin and nitrofurantoin and most resistant to ampicillin and nalidixic acid. Conclusion: Though various microorganisms are responsible for urinary tract infection in children, Escherichia coli is the most common causative agent. Antimicrobial resistance has already emerged against many antibiotics, making empiric treatment of these infections challenging. DOI: http://dx.doi.org/10.3126/jkmc.v3i1.10919Journal of Kathmandu Medical CollegeVol. 3, No. 1, Issue 7, Jan.-Mar., 2014, Page: 21-25

Sign in / Sign up

Export Citation Format

Share Document