scholarly journals The contemporary role of blood products and components used in trauma resuscitation

2010 ◽  
Vol 18 (1) ◽  
pp. 63 ◽  
Author(s):  
David J Dries
Keyword(s):  
Blood Products ◽  
Trauma Resuscitation

scholarly journals A review of the use of blood and blood products in HIV-infected patients

2012 ◽  
Vol 13 (2) ◽  
Author(s):  
Karen van den Berg
Keyword(s):  
Transfusion Medicine ◽  
Blood Products ◽  
Ethical Considerations ◽  
Appropriate Use ◽  
Hiv Patients ◽  
Hiv Negative

Despite numerous publications on the appropriate use of blood and blood products, few specifically consider the role of transfusion in the management of HIV. This review is a synthesis of conditions encountered in the management of HIV-infected patients where the transfusion of blood or blood products may be indicated. A consistent message emerging from the review is that the principles of transfusion medicine do not differ between HIV-negative and -positive patients. The aim of the review is to provide clinicians with a practical and succinct overview of the haematological abnormalities and clinical circumstances most commonly encountered in the HIV setting, while focusing on the rational and appropriate use of blood and blood products for HIV patients. Important ethical considerations in dealing with both the collection and transfusion blood and blood products in the HIV era have also been addressed. S Afr J HIV Med 2012;13(2):87-103.

scholarly journals The role of pre-hospital blood gas analysis in trauma resuscitation

2010 ◽  
Vol 5 (1) ◽  
pp. 10 ◽  
Author(s):  
Milla Jousi ◽  
Janne Reitala ◽  
Vesa Lund ◽  
Ari Katila ◽  
Ari Leppäniemi
Keyword(s):  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Blood Gas ◽  
Trauma Resuscitation

Blood Products In Trauma Resuscitation

2006 ◽  
Vol 152 (3) ◽  
pp. 121-127 ◽  
Author(s):  
J. Hutt ◽  
L. Wallis
Keyword(s):  
Blood Products ◽  
Trauma Resuscitation

The Gulf War: The Experience of a Department of Anesthesiology in the Management of Scud Missile Casualties

1997 ◽  
Vol 12 (2) ◽  
pp. 38-42 ◽  
Author(s):  
Yaw Adu-Gyamfi
Keyword(s):  
Operating Room ◽  
Operating Rooms ◽  
United States Military ◽  
Blood Products ◽  
Successful Management ◽  
The University ◽  
Two Peaks ◽  
Missile Attack ◽  
Main Operating

AbstractBackground:The pivotal role of anesthesiologists in the implementation of disaster plans is not widely appreciated.Objective:To describe the role of anesthesiologists as managers in the operating room (OR) especially during hospital disaster management.Methods:On 25 February 1991, King Fahd Hospital of the University in Eastern Saudi Arabia, was alerted, received, triaged, and treated the victims of a Scud missile attack on a United States military barracks which killed 28 and injured more than 100 service personnel.Results:There were 47 males and 15 females admitted to the hospital. Their initial triage categories of injuries were: 1) red, 23; 2) yellow, 27; and 3) green, 7. The flow of patients through the main operating rooms occurred in two peaks: 1) treated within nine hours (60%); and 2) during the next 11 hours (40%). A total 101 units of blood and blood products were consumed.The role of the Chief of Anesthesiology was vital in the dynamics of the situation regarding appropriate deployment of staff and ensuring an orderly throughput of victims in the operating room. He also was required to keep track of resources and supply levels in the operating room, so that he could advise the hospital administration appropriately.Conclusion:The successful management of a large multi-casualty incident, which involved use of the operating rooms, depended upon the efficient coordination of clearly defined functions with the Chief of Anesthesiology Service as the team leader.

The role of hypertonic saline dextran in trauma resuscitation

Trauma ◽  
2002 ◽  
Vol 4 (4) ◽  
pp. 189-201 ◽  
Author(s):  
AM Perera ◽  
KM Porter
Keyword(s):  
Hypertonic Saline ◽  
Trauma Resuscitation

scholarly journals The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation

Blood ◽  
2013 ◽  
Vol 122 (3) ◽  
pp. 376-385 ◽  
Author(s):  
Brenden W. Smith ◽  
Sarah S. Rozelle ◽  
Amy Leung ◽  
Jessalyn Ubellacker ◽  
Ashley Parks ◽  
...  
Keyword(s):  
Aryl Hydrocarbon Receptor ◽  
Cell Expansion ◽  
Progenitor Cell ◽  
Hematopoietic Progenitor Cell ◽  
Blood Products ◽  
Hematopoietic Progenitor ◽  
Aryl Hydrocarbon ◽  
Key Points

Key Points This breakthrough involves the role of the aryl hydrocarbon receptor in the expansion and specification of hematopoietic progenitor cells. This work sets a precedent for the use of an in vitro platform for the clinically relevant production of blood products.

Management of Hepatic Coagulopathy in Bleeding and Nonbleeding Patients: An Evidence-Based Review

2020 ◽  
pp. 088506662090302
Author(s):  
Nicholas W. Lange ◽  
David M. Salerno ◽  
Karen Berger ◽  
Melissa M. Cushing ◽  
Robert S. Brown
Keyword(s):  
Management Strategies ◽  
Bleeding Risk ◽  
Coagulation Factors ◽  
International Normalized Ratio ◽  
Blood Products ◽  
Clotting Cascade ◽  
Clinically Significant ◽  
Pharmacologic Agents

Patients with varying degrees of hepatic dysfunction often present with presumed bleeding diathesis based on interpretation of routine measures of coagulation (prothrombin time [PT], international normalized ratio [INR], and activated partial thromboplastin time). However, standard markers of coagulation do not reflect the actual bleeding risk in this population and may lead to inappropriate administration of hemostatic agents and blood products. The concept of “rebalanced hemostasis” explains both the risk of bleeding and clotting seen in patients with liver dysfunction. The role of pharmacologic agents and blood products for prevention of bleeding during high-risk procedures and treatment of clinically significant bleeding remains unclear. Viscoelastic measurements of the clotting cascade provide information about platelets, fibrinogen/fibrin polymerization, coagulation factors, and fibrinolysis that might better represent hemostasis in vivo and may better inform management strategies. Due to the paucity of available data, firm recommendations for the use of blood products and pharmacologic agents in patients with hepatic coagulopathies are lacking, and thus, these products should not be routinely administered. Traditional laboratory tests such as PT/INR should not be the sole determinant of potential interventions. Rather, clinicians should assess factors such as the severity of bleed or bleeding risk of the procedure, the patient’s risk of thromboembolism, and the strength of available evidence for specific agents and blood products to guide decision-making.

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