scholarly journals Perioperative fluid balance affects staging of acute kidney injury in postsurgical patients: a retrospective case-control study

2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Yu Horiguchi ◽  
Akinori Uchiyama ◽  
Naoya Iguchi ◽  
Kanaki Sakai ◽  
Daisuke Hiramatsu ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Fluid Balance ◽  
Case Control Study ◽  
Kidney Injury ◽  
Case Control ◽  
Retrospective Case ◽  
Control Study

scholarly journals Acute kidney injury in 3182 patients admitted with COVID-19: a single center retrospective case-control study

2021 ◽  
Author(s):  
Fabio L Procaccini ◽  
Roberto Alcázar Arroyo ◽  
Marta Albalate Ramón ◽  
Esther Torres Aguilera ◽  
Juan Martín Navarro ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Kidney Disease ◽  
Respiratory Distress ◽  
Kidney Function ◽  
Case Control Study ◽  
Kidney Injury ◽  
Case Control ◽  
Retrospective Case ◽  
Control Study

Abstract Background Acute kidney injury (AKI) may develop in COVID-19 patients and may be associated with a worse outcome. The aim of this study is to describe AKI incidence during the first 45 days of the SARS-CoV2 pandemic in Spain, its reversibility and the association with mortality. Methods Observational retrospective case-control study based on patients hospitalized between March 1 and April 15, 2020 with SARS-CoV2 infection and AKI. Confirmed AKI cases were compared with stable kidney function patients for baseline characteristics, analytical data, treatment and renal outcome. Patients with end-stage kidney disease were excluded. Results AKI incidence was 17.22% among 3182 admitted COVID-19 patients and acute kidney disease (AKD) incidence was 6.82%. The most frequent causes of AKI were prerenal (68.8%) and sepsis (21.9%). Odds ratio for AKI was increased in patients with pre-existent hypertension (OR 2.58, 95% CI 1.71-3.89) and chronic kidney disease (OR 2.14, 95% CI 1.33-3.42) and in those with respiratory distress (OR 2.37, 95% CI 1.52-3.70). Low arterial pressure at admission increased the risk for stage 3 AKI (OR 1.65, 95% CI 1.09-2.50). Baseline kidney function was not recovered in 45.73% of overall AKI cases and in 52.75% of AKI patients with prior chronic kidney disease. Mortality was 38.5% compared to 13.4% of the overall sample population. AKI increased mortality risk at any time of hospitalization (HR 1.45, 95% CI 1.09-1.93). Conclusions AKI is frequent in COVID-19 patients and is associated to mortality, independently from acute respiratory distress syndrome. AKD was also frequent and merits adequate follow-up.

scholarly journals Early Acute Kidney Injury Associated with Liver Transplantation: A Retrospective Case-Control Study

2020 ◽  
Vol 26 ◽  
Author(s):  
Mengzhuo Guo ◽  
Yuanchao Gao ◽  
Linlin Wang ◽  
Haijing Zhang ◽  
Xian Liu ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Acute Kidney Injury ◽  
Case Control Study ◽  
Kidney Injury ◽  
Case Control ◽  
Retrospective Case ◽  
Control Study

scholarly journals Association of proton pump inhibitors and concomitant drugs with risk of acute kidney injury: a nested case–control study

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e041543
Author(s):  
Keiko Ikuta ◽  
Shunsaku Nakagawa ◽  
Kenji Momo ◽  
Atsushi Yonezawa ◽  
Kotaro Itohara ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Case Control Study ◽  
Kidney Injury ◽  
Case Control ◽  
Renal Diseases ◽  
Increased Risk ◽  
Nested Case Control ◽  
Control Study

ObjectivesThis study aimed to assess whether the combined use of proton pump inhibitors (PPIs) with non-steroidal anti-inflammatory drugs (NSAIDs) or antibiotics (penicillins, macrolides, cephalosporins or fluoroquinolones) was associated with an increased risk of acute kidney injury (AKI).DesignA nested case–control study.SettingA health insurance claims database constructed by the Japan Medical Data Center.ParticipantsPatients were eligible if they were prescribed a PPI, NSAID and antibiotic at least once between January 2005 and June 2017. The patients who were new PPI users and did not have any history of renal diseases before cohort entry were included (n=219 082). The mean age was 45 and 44% were women.InterventionsCurrent use of PPIs, NSAIDs, or antibiotics.Primary outcome measuresAcute kidney injury.ResultsDuring a mean follow-up of 2.4 (SD, 1.7) years, 317 cases of AKI were identified (incidence rate of 6.1/10 000 person-years). The current use of PPIs was associated with a higher risk of AKI compared with past PPI use (unadjusted OR, 4.09; 95% CI, 3.09 to 5.44). The unadjusted ORs of AKI for the current use of PPIs with NSAIDs, cephalosporins and fluoroquinolones, compared with the current use of PPIs alone, were 3.92 (95% CI, 2.40 to 6.52), 2.57 (1.43 to 4.62) and 3.08 (1.50 to 6.38), respectively. The effects of concurrent use of PPIs with NSAIDs, cephalosporins or fluoroquinolones remain significant in the adjusted model. The analyses on absolute risk of AKI confirmed the results from the nested case–control study.ConclusionsConcomitant use of NSAIDs with PPIs significantly increased the risk for AKI. Moreover, the results suggested that concomitant use of cephalosporins or fluoroquinolones with PPIs was associated with increased risk of incident AKI.

scholarly journals Correction to: Is metformin associated with acute kidney injury? A case–control study of patients with type 2 diabetes admitted with acute infection

2020 ◽  
Author(s):  
Philip Andreas Schytz ◽  
Anders Bonde Nissen ◽  
Kristine Hommel ◽  
Morten Schou ◽  
Karl Emil Nelveg-Kristensen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Acute Kidney Injury ◽  
Case Control Study ◽  
Acute Infection ◽  
Kidney Injury ◽  
Case Control ◽  
Control Study

Acute kidney injury as a risk factor of hyperactive delirium: A case control study

2020 ◽  
Vol 55 ◽  
pp. 194-197 ◽  
Author(s):  
RYY Wan ◽  
CA McKenzie ◽  
D Taylor ◽  
L Camporota ◽  
M Ostermann
Keyword(s):  
Acute Kidney Injury ◽  
Risk Factor ◽  
Case Control Study ◽  
Kidney Injury ◽  
Case Control ◽  
Control Study

scholarly journals Anemia, Blood Transfusion, and Filter Life Span in Critically Ill Patients Requiring Continuous Renal Replacement Therapy for Acute Kidney Injury: A Case-Control Study

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Hasan M. Al-Dorzi ◽  
Nora Ali Alhumaid ◽  
Nouf Hamad Alwelyee ◽  
Nouf Mubark Albakheet ◽  
Ramah Ibrahim Nazer ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Replacement Therapy ◽  
Blood Transfusion ◽  
Life Span ◽  
Case Control Study ◽  
Kidney Injury ◽  
Case Control ◽  
Hemoglobin Level ◽  
Filter Life ◽  
Control Study

Background. Filter clotting is frequent during continuous renal replacement therapy (CRRT), which increases anemia risk. We studied anemia and blood transfusion in critically ill patients requiring CRRT for acute kidney injury and assessed the relationship between CRRT filter life span and PRBC transfusion. Methods. A case-control study was conducted at a tertiary-care intensive care unit (ICU) where CRRT cases were matched with controls for age, gender, admission category, and severity of illness. Daily hemoglobin levels, blood transfusions, and life span of CRRT filter were noted. CCRT patients were categorized according to the median of the filter life span (20 hours). Results. Ninety-five cases and 102 controls were enrolled. The hemoglobin level on admission was similar in the two groups, yet cases had significantly lower hemoglobin levels than controls (72.8 ± 15.3 versus 82.5 ± 20.7 g/L, p<0.001) during ICU stay. Anemia <70 g/L occurred in 50% of cases and 19% of controls (p<0.001). Most (56.3%) cases were transfused compared with 29.9% for controls (p<0.001) with higher number of transfused packed red blood cell (PRBC) units in cases (2.6 ± 4.0 versus 1.5 ± 3.2 units per patient, p=0.03). Patients with shorter versus longer filter life had similar hemoglobin level in the first 7 days of CRRT with no difference in PRBC transfusion requirement. Prefilter heparin use and hemodialysis access location were not associated with longer filter life span. The mortality was similar in patients with shorter versus longer filter life. Conclusions. CRRT in ICU was associated with larger drop in hemoglobin and more PRBC transfusion. Shorter (<20 hours) versus longer CCRT filter life was not associated with increased PRBC transfusion.

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