Additive effect of resistant starch on oral rehydration therapy and zinc supplementation for children with acute diarrhoea

2012 ◽  
Author(s):  
B S Ramakrishna
2017 ◽  
Vol 36 (3) ◽  
pp. 250-255 ◽  
Author(s):  
Dillip Kumar Dash ◽  
Mrutunjaya Dash ◽  
M.D. Mohanty ◽  
Naresh Acharya

Introduction: Administration of S. boulardii in addition to rehydration therapy in diarrhea found to be beneficial in many aspects owing to a variety of causes and importantly it is was not associated with any adverse effects.Material and Methods: We conducted a prospective study of children suffering from acute diarrhoea, at a private tertiary care hospital. Children were divided into 2 groups randomly as per odd(Group 1 ) and even (Group 2) bed allotted in indoor at the time of admission: Group 1 included children on oral rehydration therapy (ORT) + Zinc + Saccharomyces boulardii (Probiotic 5 billion CFU twice daily) and Group 2 comprised of children on ORT+ Zinc. Our objective was to systematically review data on the effect of S. boulardii on acute childhood diarrhoea.Results: Out of a total of 126 children less than 2 years, 2-6 years and 6-14 years were 72 (57.14%), 42(33.33%) and 12(09.52%) respectively. The duration of diarrhoea in Group 1 was 26.31 hours and Group 2 was 47.81 hours (p<0.01). The frequency of diarrhoea showed improvement within 24 and 72 hours in Group 1 and Group 2 respectively (p<0.01).Similarly, the mean duration of hospital stay was 2.68 days in Group 1 and 4.8 days in Group 2.The treatment cost was INR 850 and INR 1650 while social cost was INR 1250 and 2600 in Group 1 and 2 respectively.Conclusion:This study shows that S. boulardii reduced the duration, frequency and hospital stay of diarrhoea thereby reducing the treatment and social costs.J Nepal Paediatr Soc 2016;36(3):250-255


2019 ◽  
Vol 28 (3-4) ◽  
pp. 67-78 ◽  
Author(s):  
Sunoto Sunoto ◽  
Suharyono Suharyono ◽  
Aswitha D. Budiarso ◽  
Adnan S. Wiharta

Oral rehydration therapy (ORT) as an appropriate technology in the treatment of acute diarrhoeal diseases (ADD) has been accepted throughout the world. It has been proved that besides lifesaving, ORT has reduced about 70-80% of the use of intravenous solution and average cost of the treatment of ADD. If there is still problem, question or doubtfulness, is the use of WHO ORS in full concentration for the neonates and young infants less than 3 months of age. During one-year period it has been treated 72 cases of ADD in young infants less than 3 months of age with moderate dehydration. They were divided into 3 groups. The first group was treated with 100 mil kg bw of fluid consisting oftwothirds as WHO ORS in full concentration for 4 hours period and the rest, one-third, was given as plain water for 2 hours period. The second group was treated with kristalyte with the Na concentration of 51 mEq/L and the third group was treated with intravenous Ringer's lactate for 6 hours period. After the end of the study only 18 patients in each group could be matched and evaluated. From clinical observation and laboratory examinations, the result of the treatment in general, statistically shows no significant difference. Diarrhoea and vomiting stopped in all groups on the second day of treatment. Hyponatremia which occurred in 3 patients in Group I and 2 patients each in Group II and III improved  after 6 hours of treatment. Acidosis was corrected in all of the treatment groups in 6 hours period. Weight gain up to 6-9% of body weight on admission was achieved after 6 hours of treatment in all groups. No complication of hypernatremia, convulsion nor hypoglycaemia in all the treatment group. From this study it could be concluded that WHO ORS is quite safe and effective as ORS with low sodium concentration and intravenous treatment, as far as it is given slowly, little by little with a strict supervision.


2017 ◽  
Vol 41 ◽  
pp. 1 ◽  
Author(s):  
Rachel Hall-Clifford ◽  
Roxanne Amerson

Objective. Diarrhea remains a leading cause of morbidity and mortality for children in low- and middle-income countries throughout the Americas. The World Health Organization (WHO) has developed guidelines on incorporating zinc supplementation (ZS) with traditional oral rehydration therapy (ORT) in order to shorten the duration of diarrheal episodes and to reduce poor health outcomes. Guatemala adopted these guidelines in 2011, but they have not yet been fully implemented at the community level. The objectives of this study were: (1) to co-design an ORT/ZS training program for community members with local health promoters that is appropriate to the local context and (2) to understand how attitudes and behaviors of community members changed after receiving training from the study promoters. Methods. In an observational study, community health promoters in rural Guatemala were trained according to WHO guidelines, and they worked collaboratively with the study team to develop a training curriculum to implement in their community. Community-based surveys, interviews, and focus group discussions were used to assess acceptability, accessibility, and availability of oral rehydration therapy and zinc supplementation. Results. Use of ORT increased from 63% to 95% among community members following training by local health promoters. Satisfaction with the service offered by health promoters increased from 63% to 90% amongst community members trained by the study promoters. However, knowledge and use of zinc supplementation remained low, which was attributable to unavailability of zinc in the study community. Conclusions. Use of trained community health promoters is an effective way to translate WHO guidelines to local contexts and overcome sociocultural barriers to care. However, the health system’s structure must support availability of essential medicines in order to effectively implement those guidelines.


2017 ◽  
Vol 1 (1) ◽  
pp. 22-29
Author(s):  
Riskiyah Riskiyah

In Indonesia, diarrhea still is one of top problem public health for causing morbidity and  many deaths. All age groups can be attacked by diarrhea, but severe disease with high mortality especially in infants and toddlers. WHO and UNICEF recommend about management of diarrhea in children namely by adding a supplementation of zinc (Zn) on oral rehydration therapy. Zinc functions in the immune system as a second messenger in signal transduction, cell immunity and nutritional immunity. Zinc also plays an important role in reducing the risk and severity of diarrhea. From some research shows that the effects of therapeutic zinc supplementation can reduce the duration of diarrhea, stool output and stool frequency. The supplementation of 20 mg of zinc per day on the eradication of child diarrhea are less than 5 years and 10 mg per day for infants less than 6 months for 10-14 days. The beneficial effects of zinc supplementation in diarrhea that can speed up the regeneration of the epithelium lining the intestine, increasing the absorption of water and electrolytes in the intestine, increase enzyme levels enterocyte brush-border, and enhance the immune response that can speed up clearance of pathogens from the gut.


2006 ◽  
Vol 42 (4) ◽  
pp. 362-368 ◽  
Author(s):  
P. Raghupathy ◽  
B. S. Ramakrishna ◽  
Samuel P. Oommen ◽  
Mir Shovkat Ahmed ◽  
G. Priyaa ◽  
...  

1989 ◽  
Vol 21 (S10) ◽  
pp. 105-113 ◽  
Author(s):  
Hoda Rashad

A major Egyptian national programme for the control of diarrhoeal disease was launched in February 1984, with the aim of reducing the dehydration-specific mortality resulting from acute diarrhoea (52% of all infant deaths in 1979) and thus to reduce overall infant and childhood mortality.


Author(s):  
Daimler Linzy Jose ◽  
Punithakumary Purushothaman ◽  
Ravi Shankar Singanallur Lakshmanan

Background: Globally, acute diarrhoea claims around 1.5 million lives of under-five children. In India, ADD accounts for 8% of deaths in <5yrs age group. Child may be pushed into an irreversible outcome as stunting because of inadequate nutrition and repeated bouts of infection during the first 1000 days of life. Oral rehydration therapy is the most effective treatment intervention which can avert about 14% of deaths in under five children.Methods: A cross sectional study was done among 270 mothers of under five children from our urban health centre service area of PSGIMSR.Results: Among 270 mothers of under five children most of them belonged to the age group of ≤25 years. Only 10.7% of the mothers were aware that infection or germs cause diarrhea, signs of dehydration were not known by 80% of mothers. Mothers’ with more than one child and mothers with education more than 8th class were emerged as the factors affecting ORS preparation.Conclusions: The knowledge on diarrhoea was low. Although awareness regarding spread of diarrhoea and ORS was adequate in this community, knowledge regarding continuation of feeding and signs of dehydration were deficient. Thus educating the mothers of under-five children regarding correct practices of home management of diarrhoea is likely to further reduce diarrhoea morbidity and mortality. 


Sign in / Sign up

Export Citation Format

Share Document