Reducing the impact of diabetic foot ulcers on patients and the NHS

2021 ◽  
Author(s):  
Christina Sheehan
Keyword(s):  
Diabetic Foot ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
The Impact

scholarly journals A Bibliometric Analysis of the Top-Cited Articles on Diabetic Foot Ulcers

2021 ◽  
Author(s):  
Jiasheng You ◽  
Chao Liu ◽  
Yixin Chen ◽  
Weifen Zhu ◽  
Shunwu Fan ◽  
...  
Keyword(s):  
Bibliometric Analysis ◽  
Diabetic Foot ◽  
Median Number ◽  
Scientific Discipline ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Level Of Evidence ◽  
Bibliometric Method ◽  
Academic Publications ◽  
The Impact

Abstract Background: Citation analysis is a bibliometric method for appraising the impact of academic publications in any given scientific discipline. There is a paucity of literature concerning influential works on diabetic foot ulcers (DFUs). Aims: To determine the top-cited articles in the field of DFU research.Methods: A bibliometric analysis of citations indexed in the Scopus and the Web of Science databases was conducted in January 2021 to determine all publications related to DFU. The 50 top-cited articles that met the inclusion criteria were ranked. Articles were evaluated for several characteristics including year of publication, country of origin, authorship, publishing journal, topic categories, publishing type and level of evidence.Results: The median number of citations per article in the list was 442 (interquartile range [IQR], 320-520), with a median of 21.8 citations (IQR, 16.5-34.5) per year since publication. The publication years ranged from 1986 to 2017, with 1998 accounting for the greatest number of studies (n = 7). The citation classics were published in 20 journals and originated from institutions in nine countries. The majority of the studies were clinical, of which expert-opinion/review with Level V evidence and clinical studies with Levels I and II evidence comprised the greater proportion in the list.Conclusions: This study identified the top-cited articles and provides useful insights into the history and development of DFU research. Our findings may serve as a quick reference for education curriculums and clinical practice, in addition to providing a foundation for further studies on this topic.

scholarly journals Understanding the relationship between depression and diabetic foot ulcers

2016 ◽  
Vol 04 (01) ◽  
pp. 017-024 ◽  
Author(s):  
Andrew Steel ◽  
John Reece ◽  
Anne-Marie Daw
Keyword(s):  
Depressive Symptoms ◽  
Diabetic Foot ◽  
Foot Ulcers ◽  
Diabetic Patients ◽  
Diabetic Foot Ulcers ◽  
Biological Relationship ◽  
The Cost ◽  
The Impact ◽  
Concept Review ◽  
The Relationship

AbstractThe prevalence of diabetes is increasing, as is the cost of managing its comorbidities. Diabetic foot ulcers (DFUs) and their complications place a considerable cost burden on the health system, and lead to a significant level of disability. The relationship between depression and diabetes is well-established. The relationship between depression and foot ulcers in diabetic patients is less well-established. The purpose of this article is to provide a current concept review of the literature from 1988 to 2013, linking DFUs and depressive symptoms, with an emphasis on the impact depressive symptoms have on healing rates of DFUs. Articles specifically focusing on the biological relationship, depression′s impact on self-care, screening for depressive symptoms, causes and cost of treating DFUs, and measuring depression were reviewed. A deeper understanding of this relationship is needed to identify causal relationships, improve treatment outcomes, and reduce healing times of DFUs.

scholarly journals Bacterial Diversity of Diabetic Foot Ulcers: Current Status and Future Prospectives

2019 ◽  
Vol 8 (11) ◽  
pp. 1935 ◽  
Author(s):  
Fatemah Sadeghpour Heravi ◽  
Martha Zakrzewski ◽  
Karen Vickery ◽  
David G. Armstrong ◽  
Honghua Hu
Keyword(s):  
Diabetic Foot ◽  
Bacterial Communities ◽  
High Sensitivity ◽  
Current Status ◽  
Foot Ulcers ◽  
High Morbidity ◽  
Diabetic Foot Ulcers ◽  
Bacterial Identification ◽  
Molecular Approaches ◽  
The Impact

Diabetic foot ulcers (DFUs) and diabetic foot infections (DFIs) are associated with reduced patient quality of life, lower-extremity amputation, hospitalization, and high morbidity and mortality. Diverse bacterial communities have been identified in DFUs/DFIs, playing a significant role in infection prognosis. However, due to the high heterogeneity of bacterial communities colonized in DFUs/DFIs, culture-based methods may not isolate all of the bacterial population or unexpected microorganisms. Recently, high sensitivity and specificity of DNA (metagenomics) and RNA (metatranscriptomics) technologies have addressed limitations of culture-based methods and have taken a step beyond bacterial identification. As a consequence, new advances obtained from DNA- and RNA-based techniques for bacterial identification can improve therapeutic approaches. This review evaluated the current state of play in aetiology of DFUs/DFIs on culture and molecular approaches, and discussed the impact of metagenomic and metatranscriptomic methods in bacterial identification approaches.

scholarly journals The Impact of the Micro-Lightguide O2C for the Quantification of Tissue Ischemia in Diabetic Foot Ulcers

Diabetes Care ◽  
2004 ◽  
Vol 27 (12) ◽  
pp. 2863-2867 ◽  
Author(s):  
S. Beckert ◽  
M. B. Witte ◽  
A. Konigsrainer ◽  
S. Coerper
Keyword(s):  
Diabetic Foot ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Tissue Ischemia ◽  
The Impact

scholarly journals Early Advanced Therapy for Diabetic Foot Ulcers in High Amputation Risk Veterans: A Cohort Study

2020 ◽  
pp. 153473462092815
Author(s):  
Margaret Doucette ◽  
Kattie M. Payne ◽  
Walter Lough ◽  
Alison Beck ◽  
Kristi Wayment ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Diabetic Foot ◽  
Comprehensive Care ◽  
Foot Ulcers ◽  
Human Amniotic Membrane ◽  
Diabetic Foot Ulcers ◽  
Advanced Therapy ◽  
Advanced Therapies ◽  
The Impact

Veterans with diabetic foot ulcers (DFUs) represent the highest percentage of lower extremity amputations (LEAs) within the Veterans Affairs (VA) population. Many veterans have additional risk factors for amputation. Few studies focus on advanced therapies for this population. This study explores the impact of early application of dehydrated human amniotic membrane allograft (DAMA) with comprehensive care on preventing amputation. This prospective, single-center cohort study (ClinicalTrials.gov Identifier NCT02632929) was conducted through Boise VA Medical Center. Patients with DFUs were objectively stratified for LEA risk. Those with moderate to high amputation risk could participate. Participants received comprehensive care and weekly application of DAMA. Primary endpoint was avoidance of major LEA. Secondary endpoint was wound epithelialization. Monitoring continued 4 months. Between July 2015 and March 2017, 20 patients (mean age 67.2 years) with 24 DFU classified as moderate (12 wounds) to high risk (12 wounds) for amputation were enrolled. Wound volumes ranged from 0.072 cm3 to 56.4 cm3. Risk factors included neuropathy (20 patients), osteomyelitis (16 wounds), exposed tendon/ligament/bone (19 wounds), Charcot (5 patients), and peripheral arterial disease (13 wounds). All subjects avoided amputation within the study period, all 24 wounds achieved re-epithelialization within 4 to 33 weeks; mean healing time 13.2 weeks. Cost for the DAMA tissue ranged from $750 to $38 150. Estimated cost for LEA ranges from $30 000 to $50 000. No treatment-related adverse events during the study period were reported. The results suggest that early and frequent application of DAMA with comprehensive care may help prevent amputation. Additional research will help inform third-party payors and clinicians.

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