scholarly journals The whole-transcriptome landscape of muscle and adipose tissues reveals the ceRNA regulation network related to intramuscular fat deposition in yak

BMC Genomics ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Hui Wang ◽  
Jincheng Zhong ◽  
Chengfu Zhang ◽  
Zhixin Chai ◽  
Hanwen Cao ◽  
...  
2014 ◽  
Vol 13 (1) ◽  
pp. 363-370
Author(s):  
L.R. Alves ◽  
R.C. Antunes ◽  
R.B. Andrade ◽  
A.A. Storti ◽  
S.L.B. Reis ◽  
...  

2020 ◽  
Vol 11 ◽  
Author(s):  
Siyuan Xing ◽  
Ranran Liu ◽  
Guiping Zhao ◽  
Lu Liu ◽  
Martien A. M. Groenen ◽  
...  

2019 ◽  
Vol 158 (3) ◽  
pp. 133-144
Author(s):  
Sheng Li ◽  
Chengzhen Chen ◽  
Menglong Chai ◽  
Jiawei Wang ◽  
Bao Yuan ◽  
...  

Bone morphogenetic protein 2 (BMP2) can mediate the signaling of R-Smads and regulate different biological functions, including adipocyte differentiation. Long noncoding RNAs (lncRNAs) can be involved in many important biological processes, including fat metabolism, as miRNA sponges. This study aimed to investigate the molecular mechanism of fat deposition and to provide useful information for the prevention and treatment of lipid-related diseases. lncRNA sequencing was performed to compare and analyze, for the first time, the expression of lncRNAs in BMP2-induced and non-BMP2-induced preadipocytes from Junmu1 pigs. In addition, functional annotation and enrichment analysis of differentially expressed lncRNA target genes were carried out. lncRNAs and mRNAs were compared and analyzed. lncRNAs were identified that may regulate adipogenesis and lipid metabolism. The results give a theoretical basis for further studies on fat deposition mechanisms and provide potential therapeutic targets for metabolic diseases.


BMC Genomics ◽  
2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Baojun Li ◽  
Liying Qiao ◽  
Lixia An ◽  
Weiwei Wang ◽  
Jianhua Liu ◽  
...  

2008 ◽  
Vol 53 (No. 12) ◽  
pp. 515-522 ◽  
Author(s):  
N. Aldai ◽  
M.E.R. Dugan ◽  
A.I. Nájera ◽  
K. Osoro

Levels of n-6 and n-3 PUFAs, including those with 20 and 22 carbon-chains, in concentrate-fed Asturiana de los Valles (AV) yearling bulls with and without the double muscling gene <I>(mh/mh</I> = 24, <I>mh</I>/+ = 26, +/+ = 25) were measured to examine if this gene influences the pattern of PUFA deposition in different adipose tissues. Fatty acid compositions of muscle tissue (<I>longissimus thoracis</I>) and intermuscular and subcutaneous adipose tissues were determined by gas chromatography. The composition of intramuscular fat was unique compared to the other two adipose tissues which were similar in composition. In general, n-6 and n-3 fatty acid elongation and desaturation products were affected by AV genotype and this effect was most evident in n-3 PUFAs of the intramuscular fat of <I>mh/mh</I> (n-6/n-3 = 11.8 and 18:2n-6/18:3n-3 = 25.3) compared to <I>mh</I>/+ and +/+ animals (mean values of n-6/n-3 = 9.86 and 18:2n-6/18:3n-3 = 15.5). PUFA elongation and desaturation end products did not accumulate to any great extent in intermuscular and subcutaneous adipose tissues. Beef from <I>mh/mh</I> cattle showed greater deposition rates of n-3 elongation and desaturation products but their absolute content of total n-3 fatty acids was lower (21 mg/100 g meat) in comparison with <I>mh</I>/+ and +/+ cattle (mean value of 25 mg/100 g meat).


2016 ◽  
Vol 2016 ◽  
pp. 1-14 ◽  
Author(s):  
Anne Listrat ◽  
Bénédicte Lebret ◽  
Isabelle Louveau ◽  
Thierry Astruc ◽  
Muriel Bonnet ◽  
...  

Skeletal muscle consists of several tissues, such as muscle fibers and connective and adipose tissues. This review aims to describe the features of these various muscle components and their relationships with the technological, nutritional, and sensory properties of meat/flesh from different livestock and fish species. Thus, the contractile and metabolic types, size and number of muscle fibers, the content, composition and distribution of the connective tissue, and the content and lipid composition of intramuscular fat play a role in the determination of meat/flesh appearance, color, tenderness, juiciness, flavor, and technological value. Interestingly, the biochemical and structural characteristics of muscle fibers, intramuscular connective tissue, and intramuscular fat appear to play independent role, which suggests that the properties of these various muscle components can be independently modulated by genetics or environmental factors to achieve production efficiency and improve meat/flesh quality.


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