scholarly journals Association between serum alanine and aspartate aminotransferase and blood pressure: a cross-sectional study of Chinese freshmen

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lijun Zhu ◽  
Zhengmei Fang ◽  
Yuelong Jin ◽  
Weiwei Chang ◽  
Mengyun Huang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Events ◽  
Total Population ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mean Values ◽  
The Mean ◽  
The Relationship ◽  
Strong Linear Relationship

Abstract Background High blood pressure is a well-recognized risk factor for cardiovascular events, and the incidence of hypertension is increasing among young people. This study investigated the relationship between ALT and AST levels and hypertension among freshmen in China. Methods This cross-sectional study was conducted in the Anhui Province from September to November 2018. A total of 3114 freshmen underwent a physical examination including testing of biochemical indicators and a standardized questionnaire. Results The overall prevalence of elevated ALT and AST were 6.8% and 2.3% among freshmen. The mean ALT and AST levels were higher in males (22.59 ± 21.98 vs.12.62 ± 10.30 U/L; 23.55 ± 12.24 vs. 20.02 ± 5.75 U/L, respectively). The prevalence of hypertension was significantly higher in men (16.1%) than in women (1.9%). The mean values of BMI, SBP, DBP, TC, TG, and LDL-C were found to be increased with elevated levels of serum ALT and AST in the quartiles (P for trend < 0.05). After adjusting for covariates, the risk of hypertension was significantly higher in the highest ALT quartile than in the lowest quartile (OR (95% CI) of 1.681 (1.028, 2.751) in males; 2.802 (1.102, 7.124) in females). A strong linear relationship was found between serum ALT levels and the odds of hypertension after adjustment for potential confounders only in total population and females (P for trend < 0.05). Conclusions These findings suggest that ALT level is significantly associated with hypertension both in male and female freshmen.

scholarly journals Evaluation of Anthropometric Indices and Biochemical Markers in Iranian Prediabetics in Hoveyzeh Located in Southwest Iran: A Cross-sectional Study

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Majed Meripour ◽  
Hashem Mohamadian ◽  
Morteza Abdullatif Khafaie
Keyword(s):  
Blood Pressure ◽  
Cross Sectional Study ◽  
Demographic Variables ◽  
Clinical Parameters ◽  
Sectional Study ◽  
Anthropometric Indices ◽  
Cross Sectional ◽  
Mean Values ◽  
Significant Difference ◽  
The Mean

Background: The number of prediabetic individuals is rising rapidly in Iran and other parts of the world. This complication seriously affects life quality and public health. Objectives: This study aimed to evaluate the anthropometric indices and biochemical measures among the prediabetic population. Methods: This cross-sectional study was conducted on prediabetic subjects in the Hoveyzeh population, Iran, during 2018 - 2019. A sample of 240 prediabetic individuals within the age range of 30-75 years enrolled in this study. The demographic characteristics, anthropometric measurements, and participants’ clinical parameters were checked out in this study. Moreover, this study investigated important demographic variables associated with anthropometric and clinical parameters. Results: The results showed that the mean values of fasting plasma glucose, triglyceride, and total cholesterol were 113.13 ± 6.8, 193.64 ± 115.44, and 193.64 ± 40.67 mg/dl, respectively. The mean values of systolic blood pressure and diastolic blood pressure (DBP) were 114.75 ± 15.25 and 73.25 ± 8.81 mmHg, respectively. The results showed no statistically significant difference between clinical and demographic variables except between DBP and marital status (P < 0.05). The prevalence of prediabetes in Hoveyzeh was closely associated with some demographic, anthropometric, and clinical variables. This study documented significant associations between height, hip circumference, and body mass index with both genders (P < 0.05). Furthermore, there was no statistical relationship between other demographic and anthropometric variables (P > 0.05). Conclusions: Based on the findings, abdominal obesity indicators may be related to prediabetes. Therefore, preventive strategies and suitable educational programs should be based on influential factors.

Effect of Medialization of the Trochlear Groove and Lateralization of the Tibial Tubercle on TT-TG Distance: A Cross-sectional Study of Dysplastic and Nondysplastic Knees

2021 ◽  
pp. 036354652098781
Author(s):  
Mathias Paiva ◽  
Lars Blønd ◽  
Per Hölmich ◽  
Kristoffer Weisskirchner Barfod
Keyword(s):  
Trochlear Dysplasia ◽  
Cross Sectional Study ◽  
Magnetic Resonance Images ◽  
Tibial Tubercle ◽  
Control Group ◽  
Trochlear Groove ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mean Values ◽  
The Mean

Background: Tibial tubercle–trochlear groove (TT-TG) distance is often used as a measure of lateralization of the TT and is important for surgical planning. Purpose: To investigate if increased TT-TG distance measured on axial magnetic resonance images is due to lateralization of the TT or medialization of the TG. Study Design: Cross-sectional study; Level of evidence, 3. Methods: A total of 84 knees (28 normal [NK], 28 with trochlear dysplasia [TD], and 28 with patellar dislocation without TD [PD]) were examined. The medial border of the posterior cruciate ligament (PCL) was chosen as the central anatomic landmark. The distance from the TT to PCL (TT-PCL) was measured to examine the lateralization of the TT. The distance from the TG to the PCL (TG-PCL) was measured to examine the medialization of the TG. Between-group differences were investigated by use of 1-way analysis of variance. Results: The mean values for TT-TG distance were 8.7 ± 3.6 mm for NK, 12.1 ± 6.0 mm for PD, and 16.7 ± 4.3 mm in the TD group ( P < .01). The mean values for TT-PCL distance were 18.5 ± 3.6 mm for NK, 18.5 ± 4.5 mm for PD, and 21.2 ± 4.2 mm in the TD group ( P = .03). The mean values for TG-PCL distance were 9.6 ± 3.0 mm for NK, 7.1 ± 3.4 mm for PD, and 5.1 ± 3.3 mm in the dysplastic group ( P < .01). Conclusion: The present results indicate that increased TT-TG distance is due to medialization of the TG and not lateralization of the TT. Knees with TD had increased TT-TG distance compared with the knees of the control group and the knees with PD. The TT-PCL distance did not differ significantly between groups, whereas the TG-PCL distance declined with increased TT-TG.

scholarly journals The relationship between ambulatory blood pressure variability and enlarged perivascular spaces: a cross-sectional study

BMJ Open ◽  
2017 ◽  
Vol 7 (8) ◽  
pp. e015719 ◽  
Author(s):  
Shuna Yang ◽  
Wei Qin ◽  
Lei Yang ◽  
Huimin Fan ◽  
Yue Li ◽  
...  
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Variability ◽  
Cross Sectional Study ◽  
Perivascular Spaces ◽  
Spearman Correlation ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

ObjectivesRecent studies reported that 24-hour ambulatory blood pressure variability (ABPV) was associated with lacunar infarction and white matter hyperintensities (WMH). However, the relationship between ABPV and enlarged perivascular spaces (EPVS) has not been investigated. Thus, our study aimed to investigate whether ABPV is associated with EPVS by 24-hour ambulatory blood pressure monitoring (ABPM).DesignWe conducted this study as a cross-sectional study.SettingsThe study was based on patients who presented for physical examinations in our hospital from May 2013 to June 2016.ParticipantsPatients with both brain MRI scans and 24-hour ABPM were included and patients with acute stroke, a history of severe stroke and some other severe diseases were excluded. A total of 573 Chinese patients were prospectively enrolled in this study.Primary and secondary outcome measuresEPVS in basal ganglia (BG) and white matter (WM) were identified on MRI and classified into three categories by the severity. WMH were scored by the Fazekas scale. Coefficient of variation (CV) and SD were considered as metrics of ABPV. Spearman correlation analysis and ordinal logistic regression analysis were used to assess the relationship between ABPV and EPVS.ResultsThere were statistical differences among the subgroups stratified by the severity of EPVS in BG in the following ABPV metrics: SD and CV of systolic blood pressure (SBP), CV of diastolic blood pressure (DBP) in 24 hours, daytime and nighttime and SD of DBP in nighttime. The above ABPV metrics were positively associated with the degree of EPVS. The association was unchanged after adjusting for confounders. Spearman correlation analysis showed ABPV was not related to the degree of EPVS in the WM.ConclusionABPV was independently associated with EPVS in BG after controlling for blood pressure, but not in the WM. Pathogenesis of EPVS in BG and WM might be different.

scholarly journals Genetic homozygosity as a marker of smoking dependency

Genetika ◽  
2020 ◽  
Vol 52 (3) ◽  
pp. 1009-1019
Author(s):  
Slavko Brankovic ◽  
Dejan Nikolic ◽  
Dragoslav Marinkovic ◽  
Suzana Cvjeticanin
Keyword(s):  
Cross Sectional Study ◽  
Male Gender ◽  
Sectional Study ◽  
Cross Sectional ◽  
Male And Female ◽  
Mean Values ◽  
Individual Variations ◽  
Significant Difference ◽  
The Mean ◽  
The Individual

The aim of our study was to evaluate the morphogenetic variability as a marker of smoking dependency in adult smokers versus controls and to investigate the presence and the degree of morphogenetic variability difference between male and female smokers versus same gender controls. The cross-sectional study evaluated 241 smokers and 185 nonsmoker individuals as controls. We analyzed 17 homozygous recessive characteristics (HRC). There was a significant difference in the individual variations of 17 HRCs between the controls and smokers (??2=61.400, p<0.001; for females ??2=79.440, p<0.001; for males ??2=84.972, p<0.001). The mean values of HRCs significantly differed between smokers and controls (MV?SEM(Controls) -4.79?0.13, MV?SEM(Smokers) -5.70?0.12; p<0.001). For males, presence of 6/17 (35.29% genetic homozygosity) HRCs (OR=6.12) was to the certain degree predictor for smoking dependency. Higher degree of genetic homozygosity, changed variability and male gender, might be some among potential numerous factors that could have impact on smoking development and dependence.

A study of growth changes in the mandible from deciduous to permanent dentition

2004 ◽  
Vol 27 (2) ◽  
pp. 137-142 ◽  
Author(s):  
Hung-Huey Tsai
Keyword(s):  
Cross Sectional Study ◽  
Permanent Dentition ◽  
Developmental Changes ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mean Values ◽  
Males And Females ◽  
The Mean ◽  
Growth Changes ◽  
Ramus Height

This cross-sectional study investigated mandibular developmental changes in untreated normal Taiwanese from the deciduous to permanent dentition. Differences in the mean values for ramus height and body length between males and females were statistically significant after eruption of the permanent second molars. SNB angles significantly increased and gonial and L1-MP angles significantly decreased from deciduous to permanent dentition in both sexes. The SN-MP angle in females significantly decreased and ramus inclination in males significantly increased from the early mixed to permanent dentition.

The Relationship Between Blood Pressure, Anthropometric Indices and Metabolic Profile in Adolescents: A Cross Sectional Study

2014 ◽  
Vol 82 (5) ◽  
pp. 445-449 ◽  
Author(s):  
Setila Dalili ◽  
Hamid Mohammadi ◽  
Seyed Mahmood Rezvany ◽  
Arsalan Dadashi ◽  
Mohammad Hassan Novin ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Profile ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Anthropometric Indices ◽  
Cross Sectional ◽  
The Relationship

scholarly journals The Relationship Between Blood Pressure and Sleep Duration in Turkish Children: A Cross-Sectional Study

2018 ◽  
Vol 10 (1) ◽  
pp. 51-58 ◽  
Author(s):  
Cengiz Bal ◽  
Ahmet Öztürk ◽  
Betül Çiçek ◽  
Ahmet Özdemir ◽  
Gökmen Zararsız ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Sleep Duration ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Turkish Children ◽  
The Relationship

Lower diastolic blood pressure in healthy subjects with vitamin K deficiency: a preliminary cross-sectional study

10.20883/181 ◽  
2016 ◽  
Vol 85 (4) ◽  
pp. 276
Author(s):  
Jan Krzysztof Nowak ◽  
Andrzej Wykrętowicz ◽  
Patrycja Krzyżanowska ◽  
Agnieszka Górna ◽  
Jarosław Tobolski ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Vitamin K ◽  
Healthy Subjects ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Vitamin K Deficiency ◽  
Cross Sectional ◽  
K Deficiency ◽  
The Relationship

Introduction. There is a growing body of evidence for the role of vitamin K in cardiovascular health. As a cofactor of carboxylation of the matrix Gla protein it prevents arterial calcification. However, the data on the relationship between vitamin K status and the blood pressure are scarce, and particularly so in persons without the burden of cardiovascular risk factors. Material and Methods. We performed a pilot cross‑sectional study, in which we hypothesized that vitamin K deficiency is associated with a higher blood pressure in young, healthy people. The concentration of protein induced by vitamin K absence‑II (PIVKA‑II) larger than 2 ng/mL was chosen as a proxy for vitamin K deficiency; it was assessed in serum using ELISA. Blood pressure was measured using a validated, automated oscillometric monitor in triplicate.Results. Twenty‑three healthy subjects were enrolled (16 female; mean age 21.3 ± 1.6 years; body mass index 20.6 ± 2.4 kg/m2). The diastolic blood pressure (DBP) was lower in vitamin K‑deficient subjects (58 ± 9 vs. 67 ± 5 mmHg, p = 0.01). The mean arterial blood pressure also differed (75 ± 9 vs. 83 ± 6, p = 0.02). PIVKA‑II levels correlated with DBP only (Pearson’s R = -0.41, p < 0.05; Spearman’s ρ ns.). Stepwise regression identified PIVKA‑II concentrations as the only independent parameter associated with DBP (adjusted R2 = 13.1%; PIVKA‑II: β = -0.41; 95%CI -1.87-(-0.00098), t = -2.08, p < 0.05).Conclusions. The relationship between vitamin K deficiency and low DBP in young adults should be investigated further.

scholarly journals The relationship between body mass index before pregnancy and the amount of weight that should be gained during pregnancy: A cross-sectional study

2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Resmiye Özdilek ◽  
Yılda Arzu Aba ◽  
Sena Dilek Aksoy ◽  
Bulat Aytek Şık ◽  
Yaşam Kemal Akpak
Keyword(s):  
Body Mass Index ◽  
Weight Gain ◽  
Pregnant Women ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean ◽  
The Relationship

Objective: To investigate the adaptation of pregnant women to the recommended weight gain range according to body mass index (BMI) and to determine the factors affecting them. Methods: This cross-sectional study was performed in a university hospital’s obstetrics and gynecology unit (tertiary center) in Turkey. This study was conducted between March 2018 and August 2018 (6 months) in pregnant women. Pregnant women with chronic disease and receiving treatment during antenatal follow-up, with twin pregnancy, with a fetus with a congenital abnormality, and nutritional disturbance were excluded from the study. Eight hundred twelve pregnant women with normal antenatal follow-up and who volunteered to participate were included in the study. Results: The mean age of the participants was 27.66±5.05 years. The mean weight and BMI before pregnancy were near standard in all participants. The group with the highest rate of recommended weight gain according to BMI before pregnancy was the group with low weight pregnant women. The ideal weight gain rate in all groups was 32%. Conclusions: The groups with overweight and obese pregnant women according to BMI before pregnancy had the highest rates of weight gain, above the recommended limits. BMI before pregnancy directly affects weight gain during pregnancy and the importance of pre-pregnancy counseling and weight loss is emphasized once again. doi: https://doi.org/10.12669/pjms.35.5.133 How to cite this:Ozdilek R, Aba YA, Aksoy SD, Sik BA, Akpak YK. The relationship between body mass index before pregnancy and the amount of weight that should be gained during pregnancy: A cross-sectional study. Pak J Med Sci. 2019;35(5):---------.  doi: https://doi.org/10.12669/pjms.35.5.133 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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