scholarly journals Prevalence of Salmonella enterica serovar Typhi infection, its associated factors and antimicrobial susceptibility patterns among febrile patients at Adare general hospital, Hawassa, southern Ethiopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Roza Nasir Awol ◽  
Dawit Yihdego Reda ◽  
Deresse Daka Gidebo
Keyword(s):  
General Hospital ◽  
Antimicrobial Susceptibility ◽  
Associated Factors ◽  
Susceptibility Testing ◽  
Venous Blood ◽  
Febrile Illness ◽  
Southern Ethiopia ◽  
Susceptibility Pattern ◽  
Cross Sectional ◽  
Antimicrobial Susceptibility Pattern

Abstract Background Salmonellas enterica serovar Typhi (S.typhi) causes typhoid fever and is a global health problem, especially in developing countries like Ethiopia. But there is a little information about prevalence and factors association with S.typhi and its antimicrobial susceptibility pattern in Ethiopia especially in the study area. The aim of this study was to determine the prevalence of S.typhi infection, its associated factors and antimicrobial susceptibility pattern among patient with a febrile illness at Adare General Hospital, Hawassa, Southern Ethiopia. Methods Hospital based cross sectional study was conducted among 422 febrile patients from May 23, 2018 to October 20, 2018. A 5 ml venous blood was collected from each febrile patient. Culture and biochemical test were performed for each isolate. Antimicrobial susceptibility testing was performed for each isolate using modified Kirby-Bauer disk diffusion techniques. Result In this study, the prevalence of S.typhi among febrile illness patients at Adare General Hospital was 1.6% [95% confidence interval (CI): 0.5–2.9]. The age of the study subjects were ranged from 15 to 65 years (mean age 32 years). It was observed that participants who came from rural area had 8 times (AOR 8.27: 95% CI: 1.33, 51.55) more likely to had S. typhi infection when compared with urban dwellers. The microbial susceptibility testing revealed that all six of S.typhi isolates showed sensitive to Ceftriaxone and all 6 isolates showed resistant to nalidixic acid and Cefotaxime and 5(83.3%) susceptible to Chloramphenicol and Ciprofloxaciline. Multidrug resistance (resistance to three or more antibiotics) was observed among most of the isolates. Conclusion S. typhi bacteraemia is an uncommon but important cause of febrile illness in our study population. Ceftriaxone therapy is a suitable empirical antibiotic for those that are unwell and suspected of having this illness. Further surveillance is required to monitor possible hanging antibiotic resistant patterns in Ethiopia.

scholarly journals Bacterial profile, antimicrobial susceptibility pattern and associated factors of community and hospital acquired urinary tract infection at Dessie referral hospital, Dessie, Northeast Ethiopia

2021 ◽  
Author(s):  
Berhanu Adugna ◽  
Bekele Sharew ◽  
Mohabaw Jemal
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antimicrobial Susceptibility ◽  
Associated Factors ◽  
Referral Hospital ◽  
Susceptibility Pattern ◽  
Antimicrobial Susceptibility Pattern ◽  
Hospital Acquired ◽  
Dessie Referral Hospital

Abstract Back ground: Urinary tract infection are one of the most common bacterial infections in the community and in the hospital. Nowadays, little is known about the status of community and hospital acquired urinary tract infection, antimicrobial susceptibility pattern and associated factors among urinary tract infection patients in Ethiopia, particularly in our study area. Methods A hospital based cross sectional study was carried out in Dessie referral hospital. A total of 422 urine samples were enrolled using systematic random sampling technique. All isolates were identified by standard microbiological techniques and their antibiotic susceptibility was done by Kirby Bauer disc diffusion method. Data was entered using Epi data version 3.1 and analyzed by SPSS software version 20. P- Value < 0.05 at 95% CI was considered as statistically significant. Result Of 422 urine samples processed 100 (23.7%) yielded bacterial isolates. About50(30.7%) and 50(19.3%) samples from hospitalized and community showed significant bacteriuria respectively. E. coli 44/103(42.7%), predominated across the two groups followed by S. aureus 25/103(24.3%), CONs,14/103(13.5%), Klebsiella spps 7/103(6.78), proteus spps 3/103(2.91), and Entrococcus spps 3/103 (2.91%). Pseudomonas spps 3/103 (2.91), Citrobacter spps 2/103(1.94%) and Acinetobacter Spp 1/103(0.999), which were isolated from only the hospitalized samples. Meropenem susceptibly was 100% in both study groups and Ampicillin resistance was documented as 83.3–100% and 76.9–100% in hospitalized and community acquired respectively. Among risk factors previous use of antibiotics, female gender, Age, Diabetics, catheterization were associated with the infection. Conclusion The present study revealed that slightly high prevalence of urinary tract infection. High antimicrobial resistance was observed to most antimicrobial drugs tested. Meropenem and Nitrofurantoin were the most active drugs for urinary tract infection. Empirical selection of antimicrobial agents should be based on antibiotic sensitivity pattern of uropathogens that prevalent in that area. Female sex, age, previous use of antibiotics, catheterization and diabetics were at risk of urinary tract infection.

scholarly journals Evaluation of Antimicrobial Susceptibility Pattern of Pathogenic Bacteria Causing Urinary Tract Infection in A Teaching Hospital

2021 ◽  
Vol 10 (9) ◽  
pp. 456-463
Author(s):  
Pradha Velu Ramya Rengaraj ◽  
Hemalatha Gurumurthy Saleem Mohamed Ali
Keyword(s):  
Staphylococcus Aureus ◽  
Urinary Tract ◽  
Teaching Hospital ◽  
Antimicrobial Susceptibility ◽  
Pathogenic Bacteria ◽  
Susceptibility Testing ◽  
Susceptibility Pattern ◽  
Gram Negative ◽  
Antimicrobial Susceptibility Pattern ◽  
Klebsiella Spp

Aims: To determine the prevalence of pathogenic bacteria causing urinary tract infections and their antibiotics susceptibility pattern from patients reporting in a tertiary care teaching hospital. Study design: Retrospective study. Place and duration of the study: Melmaruvathur Adhiparasakthi Institute of Medical Sciences and Research, January 2017 to December 2019. Methodology: 7825Mid-stream urine (MSU) samples collected for culture and sensitivity testing, sent to the laboratory during the period of study were included in this study. The samples were inoculated onto blood agar and MacConkey agar, incubated at 37°C for 24 hours. Identification of organisms by biochemical tests and antibiotic susceptibility testing were done by standard microbiological methods. Results: Out of 7825 samples, 3832 showed significant bacteriuria, of which 50% (1924/3832) were females. Escherichia coli was the most common pathogen isolated, which accounts for 41% followed by Klebsiella spp. (27%), Staphylococcus aureus (7%), Proteus spp. (7%), Acinetobacter spp. (5%), Pseudomonas spp. (4%), Enterobacter spp. (4%), Citrobacter spp.(4%), and Serratia spp. (0.9%). The antimicrobial susceptibility testing of Staphylococcus aureus showed 33% were Methicillin Resistant Staphylococcus aureus. The antimicrobial susceptibility pattern of gram negative bacilli showed high resistance to cephalosporins followed by carbapenems. Among gram negative bacilli, Klebsiella spp. showed 36% extended spectrum beta lactamases (ESBL) production. Conclusions: This study determines the trends in antimicrobial sensitivity patterns of uropathogens. It is helpful in the formulation of local antibiotic policy for the hospital and assist clinicians in the rational choice of antibiotic therapy to prevent misuse or overuse of antibiotics so as to prevent emergence of multi drug resistant pathogens.

scholarly journals Magnitude of Episiotomy and Associated Factors among Mothers Who Give Birth in Arba Minch General Hospital, Southern Ethiopia: Observation-Based Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Kassahun Fikadu ◽  
Negussie Boti ◽  
Birtukan Tadesse ◽  
Dureti Mesele ◽  
Emenet Aschenaki ◽  
...  
Keyword(s):  
General Hospital ◽  
Associated Factors ◽  
Occupational Status ◽  
Sampling Technique ◽  
Educational Status ◽  
Cross Sectional Study ◽  
Southern Ethiopia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Study Participants

Background. Episiotomy is the most common obstetric procedure, performed when the clinical circumstances place the patient at a high risk of high-degree laceration. However, episiotomy should be done with judicious indication to lower perineal laceration with fewer complications. Despite its adverse effects, the magnitude of episiotomy is increasing due to different factors. Therefore, this study is aimed at determining the recent magnitude of episiotomy and at identifying associated factors among women who gave delivery in Arba Minch General Hospital, Southern Ethiopia. Methods. An institution-based cross-sectional study was conducted from December 15, 2018, to January 30, 2019. A systematic random sampling technique was used to select study participants. A semistructured questionnaire was used to collect data. This was supplemented with a review of the labor and delivery records. Binary and multivariable logistic regression analyses were performed to identify factors associated with the magnitude of episiotomy. P value ≤ 0.05 was used to determine the level of statistically significant variables. Results. The magnitude of episiotomy was found to be 272 (68.0%) with 95%CI=64.0‐72.5. Women who attended secondary education [AOR=10.24, 95%CI=2.81‐37.34], women who attended college and above [AOR=4.61, 95%CI=1.27‐16.71], birth weight≥3000 g [AOR=4.84, 95%CI=2.66‐8.82], primipara [AOR=4.13, 95%CI=2.40‐7.12], being housewife occupants [AOR=3.43, 95%CI=1.20‐9.98], married women [AOR=2.86, 95%CI=1.40‐5.84], and body mass index<25 kg/m2 [AOR=2.85, 95%CI=1.50‐5.44] were independent variables found to have significant association with episiotomy. Conclusion. The magnitude of episiotomy was 68.0% which is higher than the recommended practice by WHO (10%). The study participants’ occupational status, marital status, educational status, parity, birth weight, and BMI were significantly associated with the magnitude of episiotomy in the study area. Therefore, to reduce the rate of episiotomy, it is better to have periodic training for birth attendants regarding the indication of episiotomy.

scholarly journals Prevalence and Antimicrobial Susceptibility Pattern of Urinary Tract Infection among Pregnant Women Attending Hargeisa Group Hospital, Hargeisa, Somaliland

2021 ◽  
Author(s):  
Abdikhaliq Hussein Ali ◽  
Dawit Yihdego Reda ◽  
Moges Desta Ormago
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
Previous History ◽  
Susceptibility Pattern ◽  
Cross Sectional ◽  
Antimicrobial Susceptibility Pattern ◽  
History Of

Abstract The aim of this study was to determine the prevalence, antimicrobial susceptibility pattern and associated factors of urinary tract infection (UTI) among pregnant women attending Hargeisa Group Hospital (HGH), Hargeisa, Somaliland. A cross-sectional study was conducted at HGH, Hargeisa, Somaliland and participants were selected by systematic random sampling technique. Clean catch midstream urine samples were collected from 422 participants and cultured and antimicrobial susceptibility pattern was determined for the isolates. Univariable and multivariable logistic regression analyses were utilized to identify the independent risk factors for UTI The prevalence of UTI was 16.4 % (95% CI: 13.3–19.9). The predominant bacteria isolate was E. coli (43.5%). Gram negative bacteria were resistant to ampicillin (96%) and tetracycline (71.4%) and Gram-positive bacteria were also resistant to ampicillin (90%), tetracycline (55%). Multidrug resistance was observed in 89.9% of bacterial isolated. No formal education participants were 3.18 times, previous history of catheterization had 3.22 times and previous history of UTI had 3.73 times more likely to develop UTI than their counterparts respectively. Culture and susceptibility test is vital for appropriate management of UTI in the study area.

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