scholarly journals Relationship between chronic exposure to ambient air pollution and mental health in Korean adult cancer survivors and the general population

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hyun-Jin Kim ◽  
Jin-young Min ◽  
Yong-Seok Seo ◽  
Kyoung-bok Min
Keyword(s):  
Mental Health ◽  
Air Pollution ◽  
Depressive Symptoms ◽  
Suicidal Ideation ◽  
General Population ◽  
Cancer Survivors ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Adult Cancer Survivors ◽  
The Individual

Abstract Background Although a significant association between air pollution and mental health has been identified, few studies have addressed this relationship based on cancer diagnosis. This study investigated whether associations between long-term air pollution and mental health conditions differ based on whether the individual has been diagnosed with cancer. Methods Nationally representative data were used and a total of 38,101 adults were included in the analyses. We assessed mental health factors such as perceived stress, depressive symptoms, and suicidal ideation, and analyzed the associations between these factors and individuals’ annual average exposure to air pollutants, including particulate matter with an aerodynamic diameter ≤ 10 μm (PM10), nitrogen dioxide, sulfur dioxide, and carbon monoxide. Results Compared with the general population, PM10 exposure in cancer survivors predicted a higher risk of depressive symptoms (odds ratio [OR] =1.34; 95% confidence interval [CI] = 1.06–1.69) and suicidal ideation (OR = 1.29; 95% CI = 1.01–1.64). Notably, the statistically significant relationship between PM10 exposure and suicidal ideation in cancer survivors disappeared after further adjustment for depressive symptoms (p = 0.3103). This pattern was also observed in the result of propensity score-matched analysis for comparison between cancer survivors and the general population. Conclusions This study provides the first evidence that cancer survivors with depressive symptoms may be more susceptible to suicidal ideation in the context of persistent PM10 exposure.

Association Between Exposure to Ambient Air Pollution and Thyroid Function in Korean Adults

2020 ◽  
Vol 105 (8) ◽  
pp. e2912-e2920
Author(s):  
Hyun-Jin Kim ◽  
Hyuktae Kwon ◽  
Jae Moon Yun ◽  
Belong Cho ◽  
Jin-Ho Park
Keyword(s):  
Air Pollution ◽  
General Population ◽  
Thyroid Function ◽  
Air Pollutants ◽  
Final Analysis ◽  
Ambient Air ◽  
Normal Weight ◽  
Ambient Air Pollution ◽  
Annual Average ◽  
Korean Adults

Abstract Context Although a significant relationship has been reported between air pollution and thyroid function in limited samples or regions, few studies have addressed this association in the general population. Objective Using a nationwide sample of Korean adults, we investigated the association between exposure to air pollution and thyroid function, and whether this association differed between subgroups stratified according to age or body mass index (BMI). Methods We included 4704 adults in the final analysis and used each person’s annual average exposure to 4 air pollutants, namely, particulate matter with an aerodynamic diameter less than or equal to 10 μm (PM10), nitrogen dioxide (NO2), sulfur dioxide, and carbon monoxide (CO). We measured serum thyrotropin (TSH) and free thyroxine (FT4) concentrations as indicators of thyroid function according to age and BMI. Results The annual average exposure to NO2 and CO was significantly associated with an elevated TSH and reduced FT4 concentration after adjusting for possible confounding factors (all P < .05). In men, in addition to these 2 pollutants, PM10 exposure was positively associated with TSH level (P = .03). Age-stratified analysis showed stronger effects of NO2 and CO exposure in older than in younger adults. Exposure to these air pollutants was related to serum TSH and FT4 concentrations in people with overweight or obesity but not in those of normal weight. Conclusions This study provides the first evidence that air pollution exposure is linked to thyroid function in the general population and that this association may be stronger in older or overweight or obese adults.

scholarly journals Ambient Air Pollution and Depressive Symptoms in Older Adults: Results from the MOBILIZE Boston Study

2014 ◽  
Vol 122 (6) ◽  
pp. 553-558 ◽  
Author(s):  
Yi Wang ◽  
Melissa N. Eliot ◽  
Petros Koutrakis ◽  
Alexandros Gryparis ◽  
Joel D. Schwartz ◽  
...  
Keyword(s):  
Older Adults ◽  
Air Pollution ◽  
Depressive Symptoms ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Boston Study

OP I – 1 Ambient air pollution and depressive symptoms in elderly women: results from the salia study

2018 ◽  
Author(s):  
Hicran Altug ◽  
Anke Hüls ◽  
Kateryna Fuks ◽  
Dorothee Suguri ◽  
Ursula Krämer ◽  
...  
Keyword(s):  
Air Pollution ◽  
Depressive Symptoms ◽  
Elderly Women ◽  
Ambient Air ◽  
Ambient Air Pollution

scholarly journals Ambient Air Pollution and Increasing Depressive Symptoms in Older Women: The Mediating Role of The Prefrontal Cortex

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 341-342
Author(s):  
Andrew Petkus ◽  
Xinhui Wang ◽  
Diana Younan ◽  
Daniel Beavers ◽  
Mark Espeland ◽  
...  
Keyword(s):  
Air Pollution ◽  
Prefrontal Cortex ◽  
Depressive Symptoms ◽  
Structural Equation Models ◽  
Brain Aging ◽  
Brain Structures ◽  
Ambient Air ◽  
Community Dwelling ◽  
Ambient Air Pollution ◽  
Prefrontal Cortical

Abstract Exposure to air pollution may accelerate brain aging and increase risk of late-life depressive symptoms (DS). Brain structures underlying these associations are unknown. Longitudinal data from 829 community-dwelling women without dementia (baseline age 81.6 ± 3.6 years old) who participated in both the Women’s Health Initiative Memory Study Magnetic Resonance Imaging study (WHIMS-MRI; 2005-06) and the WHIMS-Epidemiology of Cognitive Health Outcomes (2008-16) were analyzed to examine whether volumetric measures of brain structures mediated associations between long-term exposure to ambient air pollutants and annual increases in DS (as measured by annually assessed 15-item Geriatric Depression Scale). Annual PM2.5 (fine particulate matter of aerodynamic diameter <2.5) and NO2 were estimated at the participants’ residence using regionalized universal kriging models and aggregated to the 3-year average prior to the WHIMS-MRI. Structural equation models were constructed to estimate associations between exposure, structural brain variables, and trajectories of DS (standardized on baseline mean and SD). Living in locations with higher NO2 (standardized β = 0.023; 95% Confidence Interval (CI) = 0.004, 0.042) or PM2.5 (standardized β = 0.021; 95% CI = 0.004, 0.038) was associated with larger annual increases in DS (~60% larger annual increase in DS). Higher NO2, but not PM2.5, was associated with smaller prefrontal cortical volumes (standardized β = -0.431; 99% CI = -0.518; -0.344). Prefrontal cortical volume explained 30.4% of the total association between annual DS increase and NO2. These findings underscore the importance of the prefrontal cortex in associations between NO2 exposure and increasing DS in later-life.

Effects of ambient air pollution on psychological stress and anxiety disorder: a systematic review and meta-analysis of epidemiological evidence

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Tanwi Trushna ◽  
Vikas Dhiman ◽  
Dharma Raj ◽  
Rajnarayan R. Tiwari
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Air Pollution ◽  
Anxiety Disorder ◽  
Anxiety Disorders ◽  
Psychological Stress ◽  
Meta Analysis ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Cochrane Library

AbstractObjectivesAmbient air pollution (AAP) is an important risk factor for increased mental health morbidity. Studies have highlighted the effect of AAP on psychological stress and anxiety disorder. However, existing evidence regarding this is largely equivocal. This systematic review with meta-analysis aims to synthesize published evidence to calculate the pooled estimate of the effect of AAP on psychological stress and anxiety disorder.ContentA systematic bibliographic search was undertaken using PubMed, JGateplus, Google Scholar, and Cochrane Library for observational human studies published in English till 31st March 2020 reporting the effect of AAP on psychological stress and anxiety disorder. Study quality was assessed using the Joanna Briggs Institute critical appraisal tools. Meta-analysis was performed adopting a random-effects model using Meta-XL. Of 412 articles retrieved, a total of 30 articles [AAP and anxiety disorders, (n=17, 57%); AAP and psychological stress, (n=9, 30%) and AAP and both psychological stress and anxiety disorders, (n=4, 13%)] fulfilled the inclusion criteria covering a total population of 973,725 individuals. The pooled estimate (OR) of the effects of PM10 on psychological stress was 1.03 [(95% CI: 1.00, 1.05) (p=0.17, I2=41%)]. The pooled estimate of the effects of NO2 and PM10 on anxiety disorder was 0.93 [(95% CI: 0.89, 0.97) (p=0.91, I2=0%)] and 0.88 [(95% CI: 0.78, 0.98) (p=0.01, I2=59%)] respectively. The pooled estimate of the effects of PM2.5 on anxiety Disorder was 0.88 [(95% CI: 0.72, 1.06) (p=0.00, I2=80%)].Summary and OutlookThe present study provides the most updated pooled estimate of the effect of AAP on psychological stress and anxiety disorder. Future studies should focus on longitudinal studies conducted in LIC and LMIC countries using uniform and standardized criteria for exposure and outcome assessment as well as robust adjustment for confounders to minimize methodological heterogeneity resulting in reliable and comparable estimation of environmental mental health burden.

scholarly journals Prenatal ambient air pollution and maternal depression at 12 months postpartum in the MADRES pregnancy cohort

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Theresa M. Bastain ◽  
Thomas Chavez ◽  
Rima Habre ◽  
Ixel Hernandez-Castro ◽  
Brendan Grubbs ◽  
...  
Keyword(s):  
Mental Health ◽  
Risk Factors ◽  
Air Pollution ◽  
Los Angeles ◽  
Maternal Depression ◽  
Low Income ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Second Trimester ◽  
Latina Women

Abstract Background Depression is the leading cause of mental health-related morbidity and affects twice as many women as men. Hispanic/Latina women in the US have unique risk factors for depression and they have lower utilization of mental health care services. Identifying modifiable risk factors for maternal depression, such as ambient air pollution, is an urgent public health priority. We aimed to determine whether prenatal exposure to ambient air pollutants was associated with maternal depression at 12 months after childbirth. Methods One hundred eighty predominantly low-income Hispanic/Latina women participating in the ongoing MADRES cohort study in Los Angeles, CA were followed from early pregnancy through 12 months postpartum through a series of phone questionnaires and in-person study visits. Daily prenatal ambient pollutant estimates of nitrogen dioxide (NO2), ozone (O3), and particulate matter (PM10 and PM2.5) were assigned to participant residences using inverse-distance squared spatial interpolation from ambient monitoring data. Exposures were averaged for each trimester and across pregnancy. The primary outcome measure was maternal depression at 12 months postpartum, as reported on the 20-item Center for Epidemiologic Studies-Depression (CES-D) scale. We classified each participant as depressed (n = 29) or not depressed (n = 151) based on the suggested cutoff of 16 or above (possible scores range from 0 to 60) and fitted logistic regression models, adjusting for potential confounders. Results We found over a two-fold increased odds of depression at 12 months postpartum associated with second trimester NO2 exposure (OR = 2.63, 95% CI: 1.41–4.89) and pregnancy average NO2 (OR = 2.04, 95% CI: 1.13–3.69). Higher second trimester PM2.5 exposure also was associated with increased depression at 12 months postpartum (OR = 1.56, 95% CI: 1.01–2.42). The effect for second trimester PM10 was similar and was borderline significant (OR = 1.58, 95% CI: 0.97–2.56). Conclusions In a low-income cohort consisting of primarily Hispanic/Latina women in urban Los Angeles, we found that prenatal ambient air pollution, especially mid-pregnancy NO2 and PM2.5, increased the risk of depression at 12 months after childbirth. These results underscore the need to better understand the contribution of modifiable environmental risk factors during potentially critical exposure periods.

Sign in / Sign up

Export Citation Format

Share Document