scholarly journals Comparative study on optic disc features of premature infants and full‐term newborns

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaofen Feng ◽  
Yan Nan ◽  
Jiandong Pan ◽  
Ruitao Zou ◽  
Lijun Shen ◽  
...  
Keyword(s):  
Optic Disc ◽  
Premature Infants ◽  
Imaging System ◽  
Full Term ◽  
Wide Field ◽  
Ring Type ◽  
Double Ring ◽  
Significant Difference ◽  
Single Ring ◽  
Term Newborns

Abstract Background To study optic disc features of premature infants and compare to that of term infants to explore the pattern and features of newborn optic disc development and provide the basis for the diagnosis of newborn optic disc disease. Methods This was a prospective clinical research. Newborns underwent newborn fundus disease screening from January 1st, 2016 to October 31st, 2016 in the neonatal ward of Ruian City Maternal and Child Health Hospital were selected. RetCam 3 Version6.1.25.0 Wide-Field Digital Pediatric Retinal Imaging System developed by Clarity Medical Systems, Inc was adopted to conduct fundus examination on both eyes, 130 degree wide-angle lens was used to film the images centering optic disc. Results For both premature infants and full-term newborns, vertical diameter of the optic disc to lateral diameter of the optic disc ratio was > 1, and the shape of the optic disc was a vertical oval. The difference of each optic disc parameter between premature infants and full-term newborns was not statistically significant (P > 0.05). There’s a difference of constitution of sclerotic ring type on optic disc between premature infants and full-term newborns. Among which, the proportion of single ring type and double ring type in premature infants was higher than that in full-term newborns (P < 0.05). The proportion of no ring type in full-term newborns was higher than that in premature infants (P < 0.05). The proportion of mixed type had no significant difference (P > 0.05) between premature infants and full-term newborns. Conclusions We found that The proportion of mature types (single ring type and double ring type) in full-term newborns was higher than that in premature infants. While there’s no statistical difference of the proportion of mixed types between premature infants and full-term newborns. Double ring type was a normal stage of the development of optic disc.

scholarly journals Comparative Study on Optic Disc Features of Premature Infants and full-term newborns

2020 ◽  
Author(s):  
Xiaofen Feng ◽  
Yan Nan ◽  
Jiandong Pan ◽  
Ruitao Zou ◽  
Lijun Shen ◽  
...  
Keyword(s):  
Optic Disc ◽  
Premature Infants ◽  
Imaging System ◽  
Full Term ◽  
Wide Field ◽  
Ring Type ◽  
Double Ring ◽  
Significant Difference ◽  
Single Ring ◽  
Term Newborns

Abstract Background: To study optic disc features of premature infants and compare to that of term infants to explore the pattern and features of newborn optic disc development and provide the basis for the diagnosis of newborn optic disc disease. Methods: This was a prospective clinical research. Newborns underwent newborn fundus disease screening from January 1st, 2016 to October 31st, 2016 in the neonatal ward of Ruian City Maternal and Child Health Hospital were selected. RetCam 3 Version6.1.25.0 Wide-Field Digital Pediatric Retinal Imaging System developed by Clarity Medical Systems, Inc was adopted to conduct fundus examination on both eyes, 130 degree wide-angle lens was used to film the images centering optic disc. Results: For both premature infants and full-term newborns, vertical diameter of the optic disc to lateral diameter of the optic disc ratio was >1, and the shape of the optic disc was a vertical oval. The difference of each optic disc parameter between premature infants and full-term newborns was not statistically significant (P>0.05). There’s a difference of constitution of sclerotic ring type on optic disc between premature infants and full-term newborns. Among which, the proportion of single ring type and double ring type in premature infants was higher than that in full-term newborns (P<0.05). The proportion of no ring type in full-term newborns was higher than that in premature infants (P<0.05). The proportion of mixed type had no significant difference (P>0.05) between premature infants and full-term newborns.Conclusions: We found that The proportion of mature types (single ring type and double ring type) in full-term newborns was higher than that in premature infants. While there’s no statistical difference of the proportion of mixed types between premature infants and full-term newborns. Double ring type was a normal stage of the development of optic disc.

scholarly journals Comparative Study on Optic Disc Features of Premature Infants and full-term newborns

2020 ◽  
Author(s):  
Xiaofen Feng ◽  
Yan Nan ◽  
Jiandong Pan ◽  
Ruitao Zou ◽  
Lijun Shen ◽  
...  
Keyword(s):  
Optic Disc ◽  
Premature Infants ◽  
Imaging System ◽  
Full Term ◽  
Wide Field ◽  
Ring Type ◽  
Double Ring ◽  
Significant Difference ◽  
Single Ring ◽  
Term Newborns

Abstract Background: To study optic disc features of premature infants and compare to that of term infants to explore the pattern and features of newborn optic disc development and provide the basis for the diagnosis of newborn optic disc disease. Methods: This was a prospective clinical research. Newborns underwent newborn fundus disease screening from January 1st, 2016 to October 31st, 2016 in the neonatal ward of Ruian City Maternal and Child Health Hospital were selected. RetCam 3 Version6.1.25.0 Wide-Field Digital Pediatric Retinal Imaging System developed by Clarity Medical Systems, Inc was adopted to conduct fundus examination on both eyes, 130 degree wide-angle lens was used to film the images centering optic disc. Results: For both premature infants and full-term newborns, vertical diameter of the optic disc to lateral diameter of the optic disc ratio was >1, and the shape of the optic disc was a vertical oval. The difference of each optic disc parameter between premature infants and full-term newborns was not statistically significant (P>0.05). There’s a difference of constitution of sclerotic ring type on optic disc between premature infants and full-term newborns. Among which, the proportion of single ring type and double ring type in premature infants was higher than that in full-term newborns (P<0.05). The proportion of no ring type in full-term newborns was higher than that in premature infants (P<0.05). The proportion of mixed type had no significant difference (P>0.05) between premature infants and full-term newborns.Conclusions: We found that The proportion of mature types (single ring type and double ring type) in full-term newborns was higher than that in premature infants. While there’s no statistical difference of the proportion of mixed types between premature infants and full-term newborns. Double ring type was a normal stage of the development of optic disc.

scholarly journals Comparative Study on Optic Disc Features of Premature Infants and Term Infants

2020 ◽  
Author(s):  
Xiaofen Feng ◽  
Yan Nan ◽  
Jiandong Pan ◽  
Ruitao Zou ◽  
Lijun Shen ◽  
...  
Keyword(s):  
Optic Disc ◽  
Premature Infants ◽  
Imaging System ◽  
Wide Field ◽  
Disc Disease ◽  
Term Infants ◽  
Ring Type ◽  
Double Ring ◽  
Significant Difference ◽  
Single Ring

Abstract Background To study optic disc features of premature infants and compare to that of term infants to explore the pattern and features of newborn optic disc development and provide the basis for the diagnosis of newborn optic disc disease. Methods This is a prospective clinical research. Newborns underwent newborn fundus disease screening from January 1st, 2016 to October 31st, 2016 in the neonatal ward of Ruian City Maternal and Child Health Hospital were selected. RetCam 3 Version6.1.25.0 Wide-Field Digital Pediatric Retinal Imaging System developed by Clarity Medical Systems, Inc was adopted to conduct fundus examination on both eyes, 130 degree wide-angle lens was used to film the images centering optic disc. Results For both premature infants and term infants, vertical diameter of the optic disc to lateral diameter of the optic disc ratio was > 1, and the shape of the optic disc was a vertical oval. The difference of each optic disc parameter between premature infants and term infants was not statistically significant (P > 0.05). There’s a difference of constitution of sclerotic ring type on optic disc between premature infants and term infants. Among which, the proportion of single ring type and double ring type in premature infants was higher than that in term infants (P < 0.05). The proportion of no ring type in term infants was higher than that in premature infants (P < 0.05). The proportion of mixed type had no significant difference (P > 0.05) between premature infants and term infants. Conclusions We found that The proportion of mature types (single ring type and double ring type) in term infants was higher than that in premature infants. While there’s no statistical difference of the proportion of mixed types between premature infants and term infants.Double ring type is a normal stage of the development of optic disc.

Neonatal eye screening for 203 healthy term newborns using a wide-field digital retinal imaging system

2019 ◽  
Author(s):  
Kenneth Teow Kheng Leong ◽  
Siti Nur Amira Abu Kassim ◽  
Jasvinjeet Kaur Sidhu ◽  
Zayani Zohari ◽  
Thivakar Sivalingam ◽  
...  
Keyword(s):  
Imaging System ◽  
Retinal Imaging ◽  
Common Finding ◽  
Wide Field ◽  
Retinal Haemorrhage ◽  
Cross Sectional ◽  
Ocular Abnormalities ◽  
Eye Screening ◽  
Term Newborns ◽  
Retinal Haemorrhages

Abstract Purpose This study aimed to determine the proportion and types of ocular abnormalities detected in healthy term newborns and also the risk factors associated with retinal haemorrhages. Method This cross-sectional study comprised of 203 participants, all healthy term newborn infants in the Obstetrics and Gynaecology ward at Hospital Kuala Lumpur over a six months period. The examination list includes external eye examination, red reflex test, and fundus imaging using a wide-field digital retinal imaging system (Phoenix Clinical ICON Paediatric Retinal Camera) by a trained Investigator. The pathologies detected were documented. The results were compared with similar studies previously published in the literature. Results Total ocular abnormalities were detected in 34% infants. The most common finding was retinal haemorrhage in 29.6% infants, of which 53.3% occurred bilaterally. Spontaneous vaginal delivery (SVD) remained the greatest risk factor which has nearly four times higher risk of newborns developing retinal haemorrhage compared to Lower Segment Caesarean Section (LSCS). There was a 6% increased likelihood of developing retinal haemorrhage for every 1 minute increment in the duration of 2nd stage of labour. Newborns delivered via SVD with episiotomy had 2.5 higher odds of developing retinal haemorrhage in newborns compared to SVD without episiotomy. Conclusion Universal eye screening for all newborns using a wide-field digital imaging system is possible, safe and useful in detecting posterior segment disorders. The most common abnormality detected is retinal haemorrhage. Although most resolve spontaneously, a longitudinal study is needed to study the long term effect of retinal haemorrhages in these infants.

Developmental pattern of muscle fiber types in human ventilatory muscles

1978 ◽  
Vol 44 (6) ◽  
pp. 909-913 ◽  
Author(s):  
T. G. Keens ◽  
A. C. Bryan ◽  
H. Levison ◽  
C. D. Ianuzzo
Keyword(s):  
Premature Infants ◽  
Full Term ◽  
Developmental Pattern ◽  
Type I ◽  
Fiber Types ◽  
Intercostal Muscles ◽  
Term Newborns ◽  
Older Subjects ◽  
Type I Fibers ◽  
Ventilatory Muscles

Premature infants tolerate respiratory loads poorly. This may reflect incomplete development of the ventilatory muscles (VM) causing poor resistance to fatigue. To study the developmental pattern of human VM, 31 postmortem specimens of diaphragm and intercostal muscles were obtained. Individual muscle fibers were classified as type I (slow-twitch, high-oxidative) or type II (fast-twich, low-oxidative) using histochemical staining methods for myofibrillar adenosine triphosphatase (M-ATPase) (pH 10.30) and nicotinamide adenine dinucleotide (NADH) tetrazolium reductase. In the diaphragm, premature infants (less than 37 wk gestation) had only 9.7 +/- 1.3% type I fibers, full-term newborns 25.0 +/- 1.1%, and older subjects (greater than 2 yr of age) 54.9 +/- 1.3%. There was no further increase after 8 mo postpartum. In the intercostal muscles, premature infants had only 19.0 +/- 4.8% type I fibers, full-term newborns 45.7 +/- 1.3%, and older subjects 65.2 +/- 2.6%. There was no further increase after 2 mo postpartum. These findings suggest the ventilatory muscles of newborn infants are more susceptible to fatigue than those of older subjects. This may contribute significantly to respiratory problems in the neonate.

scholarly journals Breastfeeding skills of full-term newborns and associated factors in a low-and-middle-income setting

2019 ◽  
Vol 19 (3) ◽  
pp. 2670-2678
Author(s):  
Esedra E Krüger ◽  
Alta AM Kritzinger ◽  
Lidia L Pottas
Keyword(s):  
South African ◽  
Early Identification ◽  
Newborn Infants ◽  
Full Term ◽  
Term Infants ◽  
Middle Income ◽  
Term Newborn ◽  
Significant Difference ◽  
Term Newborns ◽  
Hiv Exposed

Background: Normative information on the breastfeeding of term newborns may guide clinicians in early identification of breastfeeding difficulties and oro-pharyngeal dysphagia (OPD), and may support optimal breastfeeding practices. Objective: To describe breastfeeding skills of term newborn infants in a South African hospital, a lower-middle-income setting, and investigate associations between infants’ feeding and other factors.Method: One breastfeeding session of each of the 71 healthy newborn full-term infants (mean chronological age=1.9 days; mean gestation=39.1 weeks) was evaluated using the Preterm Infant Breastfeeding Behavior Scale (PIBBS), suitable for use with term newborns.Results: All participants were exclusively breastfed. Thirteen participants (18%) were HIV-exposed. There was no significant difference in the findings of the PIBBS between HIV-exposed and unexposed participants. Most newborns had obvious rooting, latched deeply onto the nipple and some of the areola, had repeated long sucking bursts (mean length=16.82 sucks/burst), and swallowed repeatedly. Most participants were in either the drowsy or quiet-alert state, which are optimal behavioural states for breastfeeding. One to two-hourly on-demand feeds was significantly associated with mothers who had normal births and did not use galactogogues to promote lactation.Conclusion: Results may be used for early identification of OPD in newborns. The findings may be useful to primary care clinicians.Keywords: Full-term, newborn, breastfeeding, feeding skills, feeding characteristics, normative data.

scholarly journals Levels of Cytokines (IL-1β, IL-2, IL-6, IL-8, TNF-α) and Trace Elements (Zn, Cu) in Breast Milk From Mothers of Preterm and Term Infants

2005 ◽  
Vol 2005 (6) ◽  
pp. 331-336 ◽  
Author(s):  
Bilal Ustundag ◽  
Erdal Yilmaz ◽  
Yasar Dogan ◽  
Saadet Akarsu ◽  
Halit Canatan ◽  
...  
Keyword(s):  
Trace Elements ◽  
Immune System ◽  
Human Milk ◽  
Premature Infants ◽  
Full Term ◽  
Mature Milk ◽  
Term Infants ◽  
Necrosis Factor Alpha ◽  
Significant Difference ◽  
Cytokine Levels

It has been well documented that human milk contains several immunomodulator components which are important during infant period when the newborn's immune system is still under development. In this study, we aim at examining levels of cytokines, zinc (Zn), and copper (Cu) in milk from mothers of premature and mature infants, and comparing changes during lactation periods consequently. Milk was collected from total of 40 mothers (group M: mothers of mature infants,n=20; group PM: mothers of premature infants,n=20) from four lactation stages: colostrum (0–7 days), transitional (7–14 days), mature milk (21 days), and mature milk (2nd month). Levels of cytokines (interleukin [IL]-lβ, IL-2, IL-6, IL-8, tumor necrosis factor-alpha [TNF-α]) were determined by chemiluminesence method, whereas atomic absorption spectrophotometer was used for the determination of Zn and Cu levels. Cytokine levels were determined to be high in colostrum and transient milk from mothers of full-term infants, whereas their levels were reduced drastically in the 21st day and the 2nd month milk (P<.01,P<.001). Similar trends were observed in milk from mothers of premature infants, but cytokine levels were significantly lower in colostrum compared to colostrum from mothers of mature infants (P<.01). The differences in cytokine levels were continuous in transient milk (P<.05) and mature milk (21 days) (P<.05), whereas there was no statistically significant differences between milk from both groups of mothers in the 2nd month (P>.05). Zn levels in milk from mothers of premature infants were significantly lower compared to the ones from mothers of mature infants (P<.01) and these differences continued through the 2nd month. Although Cu levels were lower in milk from mothers of premature infants, there was no statistically significant difference except colostrum (P>.05). Our results clearly demonstrate that the level of immunomodulating agents such as cytokines and trace elements in milk from mothers of premature infants is less than the level of the same agents in milk from mothers of full-term infants. Although there are commercially available products for infant feeding, human milk is still the best natural nutrient for newborns. Therefore, when premature infants are breastfed, necessary precautions such as supplemantary diets must be considered for possible infections and risks related with immune system deficiency.

Troponin

2013 ◽  
Vol 32 (5) ◽  
pp. 365-368 ◽  
Author(s):  
Daniele Ottinger ◽  
Patricia Nash
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Premature Infants ◽  
Cardiac Troponin ◽  
Neonatal Intensive Care ◽  
Troponin T ◽  
Full Term ◽  
Literature Analysis ◽  
Term Newborns

Troponin T and I can be found within the myocardial filaments. Measuring these cardiac troponin levels in full-term newborns and premature infants has not become a common practice in the neonatal intensive care unit and newborn nurseries. Research studies are discovering that an elevation in troponin T and I levels can be directly correlated with the severity of the infant’s illness, and it can be potentially prognostic of morbidity. This literature analysis discusses what can be considered normal cardiac troponin levels along with what elevated levels are and possible conditions associated with those elevations.

scholarly journals Music in premature infants enhances high-level cognitive brain networks

2019 ◽  
pp. 201817536 ◽  
Author(s):  
Lara Lordier ◽  
Djalel-Eddine Meskaldji ◽  
Frédéric Grouiller ◽  
Marie P. Pittet ◽  
Andreas Vollenweider ◽  
...  
Keyword(s):  
Intensive Care ◽  
Intensive Care Units ◽  
Premature Infants ◽  
Neonatal Intensive Care ◽  
Environmental Enrichment ◽  
Brain Networks ◽  
Full Term ◽  
Neonatal Intensive Care Units ◽  
Salience Network ◽  
Term Newborns

Neonatal intensive care units are willing to apply environmental enrichment via music for preterm newborns. However, no evidence of an effect of music on preterm brain development has been reported to date. Using resting-state fMRI, we characterized a circuitry of interest consisting of three network modules interconnected by the salience network that displays reduced network coupling in preterm compared with full-term newborns. Interestingly, preterm infants exposed to music in the neonatal intensive care units have significantly increased coupling between brain networks previously shown to be decreased in premature infants: the salience network with the superior frontal, auditory, and sensorimotor networks, and the salience network with the thalamus and precuneus networks. Therefore, music exposure leads to functional brain architectures that are more similar to those of full-term newborns, providing evidence for a beneficial effect of music on the preterm brain.

scholarly journals Energy Metabolism in the Erythrocytes of Premature Infants Compared to Full Term Newborn Infants and Adults

Blood ◽  
1963 ◽  
Vol 21 (6) ◽  
pp. 755-763 ◽  
Author(s):  
RUTH T. GROSS ◽  
ELEANOR A. R. SCHROEDER ◽  
SUSAN A. BROUNSTEIN
Keyword(s):  
Energy Metabolism ◽  
Pyruvate Kinase ◽  
Premature Infants ◽  
Newborn Infants ◽  
Full Term ◽  
Percentage Content ◽  
Term Newborn ◽  
Level Of Activity ◽  
Phosphoglyceric Acid ◽  
Term Newborns

Abstract 1. The following aspects of energy metabolism have been compared in the erythrocytes of premature infants, full term newborn infants, and adults: levels of activity of the enzymes involved in the generation and utilization of ATP, and measurements of the content of ATP and of ADP. 2. The levels of activity of hexokinase, phosphoglyceric acid kinase and pyruvate kinase are significantly increased in the erythrocytes of premature and full term newborn infants compared to adults. 3. The level of activity of phosphofructokinase is significantly decreased in the erythrocytes of premature and full term newborn infants compared to adults. 4. In the erythrocytes of premature infants the content of ATP is significantly increased compared to both full term newborns and adults. The content of ADP is not increased. The percentage content of ADP is significantly below the values found in full term newborn infants and adults. 5. In the erythrocytes of full term newborn infants the content of both ATP and ADP is significantly greater than in adults. The ratio of ADP to the total amount of ATP plus ADP does not differ from the adult value.

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