scholarly journals Risk factors of kidney stone disease: a cross-sectional study in the southeast of Iran

BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Parvin Khalili ◽  
Zahra Jamali ◽  
Tabandeh Sadeghi ◽  
Ali Esmaeili-nadimi ◽  
Maryam Mohamadi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Health Care Providers ◽  
Kidney Stones ◽  
Kidney Stone ◽  
Adult Population ◽  
Stone Disease ◽  
Care Providers ◽  
Baseline Phase ◽  
Kidney Stone Disease ◽  
History Of

Abstract Background The prevalence of kidney stones in the world is increasing and environmental factors seem to play a major role in this issue. The aim of the present study was to investigate the prevalence of risk factors of kidney stones in the adult population of Rafsanjan city based on the data of the Rafsanjan Cohort Study (RCS). Methods In the baseline phase of this study, 10,000 people aged 35 to 70 years are enrolled in the RCS, as one of the prospective epidemiological research studies in Iran. From this population, 9932 participants completed related demographic questionnaires as well as reported a history of diabetes mellitus, kidney stone, and hypertension diseases. The obtained data were analyzed using univariable and multivariable logistics regression. Results According to the obtained results, 46.54% of the studied population were male and 53.46% were female. The mean age of the participants was 49.94 ± 9.56 years. 2392 people accounting for 24.08% of the population had kidney stones. After adjustment of the variables, six variables of gender, WSI, no consumption of purified water, BMI, and history of hypertension and diabetes were found to be significant related factors of kidney stone disease. Conclusions Gender, hypertension, obesity, diabetes, and personal habits like alcohol consumption, opium use and, cigarette smoking are effective in the development of kidney stones. So, by identifying the susceptible patients and teaching them, the burden of the disease on society and the individual can be reduced. The results of this study are helpful to health care providers for preventive planning for kidney stone disease.

scholarly journals Secondhand smoke increases the risk of developing kidney stone disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Chien-Heng Chen ◽  
Jia-In Lee ◽  
Jhen-Hao Jhan ◽  
Yung-Chin Lee ◽  
Jiun-Hung Geng ◽  
...  
Keyword(s):  
Kidney Stones ◽  
Secondhand Smoke ◽  
Kidney Stone ◽  
Kidney Diseases ◽  
Stone Disease ◽  
Exposure Group ◽  
Kidney Stone Disease ◽  
History Of ◽  
Developing Kidney ◽  
Never Smokers

AbstractResearch indicates smoking increases the risk of various kidney diseases, although the risk of developing kidney stone disease in non-smokers exposed to secondhand smoke is unknown. This study analyzed a total of 19,430 never-smokers with no history of kidney stone disease who participated in the Taiwan Biobank from 2008 to 2019. They were divided into two groups by secondhand smoke exposure; no exposure and exposure groups; the mean age of participants was 51 years, and 81% were women. Incident kidney stone development was observed in 352 (2.0%) and 50 (3.3%) participants in the no exposure and exposure groups during a mean follow-up of 47 months. The odds ratio (OR) of incident kidney stone was significantly higher in the exposure group than the no exposure group [OR, 1.64; 95% confidence interval (95% CI) 1.21 to 2.23]. Participants with > 1.2 h per week exposure were associated with almost twofold risk of developing kidney stones compared with no exposure (OR, 1.92; 95% CI 1.29 to 2.86). Our study suggests that secondhand smoke is a risk factor for development of kidney stones and supports the need for a prospective evaluation of this finding.

scholarly journals Association of Increased Body Mass Index and Waist to Hip Ratio with Kidney Stone Disease: a prospective analysis of 493,410 UK Biobank participants

2021 ◽  
Vol 2 (4) ◽  
Author(s):  
Catherine Lovegrove
Keyword(s):  
Waist Circumference ◽  
Kidney Stones ◽  
Kidney Stone ◽  
Stone Disease ◽  
Uk Biobank ◽  
Kidney Stone Disease ◽  
University Of Oxford ◽  
Increased Risk ◽  
Nuffield Department ◽  
The Uk

Catherine E Lovegrove1,2 – [email protected] Littlejohns3- [email protected] Allen3- [email protected] A Howles1,4- [email protected] W Turney 1,2- [email protected] 1 Department of Urology, Oxford University Hospitals NHS Trust, Oxford, Oxfordshire, UK2 University of Oxford Nuffield Department of Surgical Sciences, Oxford, Oxfordshire, UK3 University of Oxford Nuffield Department of Public Health, Oxford, Oxfordshire, UK4 Academic Endocrine Unit, Radcliffe Department of Medicine, University of Oxford, Oxford, UK   Objectives To investigate the relationship between measures of adiposity and risk of incident kidney stone disease. Patients and methods The UK Biobank is a prospective cohort study of ~500,000 participants whose height, weight, BMI, waist circumference, hip circumference, waist:hip ratio (WHR), total fat mass, fat-free mass, body-fat percentage and percentage truncal fat were measured at enrolment with linkage to medical records. ICD-10 and OPCS codes were used to identify individuals with a new diagnosis of nephrolithiasis from 2006-2010. Individuals with a history of kidney stones or incomplete data were excluded. Multivariate Cox-proportional hazard models were used to assess associations between anthropometric measures and incident kidney stones. Results From the UK Biobank, 493,410 individuals were identified for inclusion; 3,466 developed a kidney stone during the study period. Increasing weight, BMI, waist and hip circumferences, WHR, and body and truncal fat were associated with increased risk of incident kidney stone disease. However, after adjustment for BMI, only waist circumference and WHR remained significantly associated with risk of nephrolithiasis. In overweight patients, high (men 94-102cm, women 80-88cm) waist circumference or WHR (men >0.9, women >0.85) conferred >40% increased risk of stone formation. Conclusion This study indicates that android fat distribution is independently associated with increased risk of developing nephrolithiasis. Kidney stone disease is known to be associated with hypertension, cardiovascular disease, and diabetes, all of which are linked to android body shape. Our findings provide insight into anthropometric risk factors for stone disease, will facilitate identification of patients at greatest risk of stone recurrence, and will inform prevention strategies.

scholarly journals KIDNEY STONE DISEASE WITH SPECIAL REGARD TO DRUG-INDUCED KIDNEY STONES – A CONTEMPORARY SYNOPSIS

2020 ◽  
Vol 73 (9) ◽  
pp. 2031-2039
Author(s):  
Łukasz Dobrek
Keyword(s):  
Urinary Tract ◽  
Kidney Stones ◽  
Kidney Stone ◽  
Stone Disease ◽  
Urinary Stones ◽  
Drug Induced ◽  
Kidney Stone Disease ◽  
Increased Risk ◽  
Endogenous Compounds

Kidney stone disease (nephrolithiasis; urolithiasis) is a clinical entity with long-term course and recurrence, primarily affecting mature and ageing men, involving the formation and presence of urinary stones in the kidneys and urinary tract. The pathogenesis of this disorder is complex and still not fully understood. A rare, potentially modifiable, form of kidney stone disease takes the form of drug-induced urinary stones. The aim of the review was a brief description of the classification and pathophysiology of kidney stone disease, along with the short characteristics of drug-induced urinary stones. This type of stones is formed as a result of crystallisation in the kidneys and urinary tract of sparingly soluble drugs and their metabolites, or as a result of metabolic changes caused by drugs, predestinating the development of stones containing endogenous compounds. Conclusion: Therefore, during treatment with the use of drugs with high lithogenic potential, the safety of pharmacotherapy should be monitored in the context of its increased risk of developing urinary stones.

KEJADIAN PNEUMONIA BALITA DI MAUMERE FLORES NUSA TENGGARA TIMUR

2016 ◽  
Vol 5 (2) ◽  
pp. 99-106
Author(s):  
Vivian Nanny Lia Dewi ◽  
Silvia Ari Agustina
Keyword(s):  
Risk Factors ◽  
Health Care Providers ◽  
Direct Observation ◽  
Care Providers ◽  
Design Data ◽  
Children Under Five ◽  
Under Five ◽  
Research Population ◽  
History Of ◽  
Significant Disease

Background: Pneumonia is the most significant disease to cause death in children compared to any other respiratoy infections, particularly in babies and children under five years old. Objective: This study aimed to investigate several risk factors for pneumonia in children under five years old in Maumere, Flores, NTT. Methods: This sudy employed collaborative qualitative-quantitative design. Data on the occurrence of pneumonia were drawn from the medical record of TC Hillers Maumere hospital, gathering information from January to July 2015. Research also involved direct observation to residents housing and interviews with health care providers and locals. Research population was children under five with a history of pneumonia, consisted of 152 children. Data were alayzed with a univariate method. Results: The majority of respondents with pneumonia were male (53.3%), co-morbid with iron deficiency anemia (20.4%), aged under 12 months (69.1%), well-nourished (56.6%), and waiting for 1-3 days at home before going to the hospital (47.5%). Direct observation suggested that Maumere was a dry and dusty area. The majority of housing roof was zinc, with topsoil floor, house ventilation were not properly adjusted, houses were over-populated, and residents still used wood and gasoline to cook. Residents had strong belief on supernatural powers. Conclusion: Risk factors that increased the occurrence of pneumonia in children under five in Maumere were age, sex, nutritional status, and environment characteristics. Keywords: pneumonia, anemia, nutrition, housing, children

Urinary stone risk factors in the descendants of patients with kidney stone disease

2018 ◽  
Vol 33 (7) ◽  
pp. 1173-1181 ◽  
Author(s):  
Thasinas Dissayabutra ◽  
Nuttiya Kalpongkul ◽  
Jakkhaphan Rattanaphan ◽  
Chanchai Boonla ◽  
Monpicha Srisa-art ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Stone ◽  
Urinary Stone ◽  
Stone Disease ◽  
Kidney Stone Disease

Effect of glycine on urinary risk factors of kidney stone disease

1989 ◽  
Vol 9 (9) ◽  
pp. 1027-1031
Author(s):  
B. Arora ◽  
M. Peacock ◽  
W.G. Robertson
Keyword(s):  
Risk Factors ◽  
Kidney Stone ◽  
Stone Disease ◽  
Kidney Stone Disease

scholarly journals Metabolic Syndrome Increases the Risk of Kidney Stone Disease: A Cross-Sectional and Longitudinal Cohort Study

2021 ◽  
Vol 11 (11) ◽  
pp. 1154
Author(s):  
Che-Wei Chang ◽  
Hung-Lung Ke ◽  
Jia-In Lee ◽  
Yung-Chin Lee ◽  
Jhen-Hao Jhan ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Kidney Stones ◽  
Kidney Stone ◽  
Large Scale ◽  
Cox Regression ◽  
Stone Disease ◽  
Cross Sectional ◽  
Longitudinal Cohort ◽  
Cox Regression Analysis ◽  
Kidney Stone Disease

We aimed to examine the association between metabolic syndrome and the risk of kidney stone development in a large-scale community-based cohort. A total of 121,579 participants enrolled in the Taiwan Biobank were analyzed. They were divided into two groups on the basis of presence of metabolic syndrome. The presence of kidney stone disease was defined by self-reported history of kidney stones. The mean age of participants was 50 years old, and self-reported kidney stones were observed in 3446 (10%) and 4292 (5%) participants with metabolic syndrome and without metabolic syndrome, respectively. Higher prevalence of kidney stone disease was found in participants with metabolic syndrome compared to those without metabolic syndrome (odds ratio (OR), 1.32; 95% confidence interval (95% CI), 1.25 to 1.39). In addition, the risk of incident kidney stone development was analyzed in a longitudinal cohort of 25,263 participants without kidney stones at baseline during a mean follow-up of 47 months. Multivariable Cox regression analysis revealed that the risk for incident kidney stone disease was higher in participants with metabolic syndrome than those without metabolic syndrome (hazard ratio, 1.24; 95% CI, 1.04 to 1.49). Our study suggests that metabolic syndrome does increase the risk of kidney stones.

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