scholarly journals Safety of psychotropic medications in people with COVID-19: evidence review and practical recommendations

BMC Medicine ◽  
2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Giovanni Ostuzzi ◽  
Davide Papola ◽  
Chiara Gastaldon ◽  
Georgios Schoretsanitis ◽  
Federico Bertolini ◽  
...  

Abstract Background The novel coronavirus pandemic calls for a rapid adaptation of conventional medical practices to meet the evolving needs of such vulnerable patients. People with coronavirus disease (COVID-19) may frequently require treatment with psychotropic medications, but are at the same time at higher risk for safety issues because of the complex underlying medical condition and the potential interaction with medical treatments. Methods In order to produce evidence-based practical recommendations on the optimal management of psychotropic medications in people with COVID-19, an international, multi-disciplinary working group was established. The methodology of the WHO Rapid Advice Guidelines in the context of a public health emergency and the principles of the AGREE statement were followed. Available evidence informing on the risk of respiratory, cardiovascular, infective, hemostatic, and consciousness alterations related to the use of psychotropic medications, and drug–drug interactions between psychotropic and medical treatments used in people with COVID-19, was reviewed and discussed by the working group. Results All classes of psychotropic medications showed potentially relevant safety risks for people with COVID-19. A set of practical recommendations was drawn in order to inform frontline clinicians on the assessment of the anticipated risk of psychotropic-related unfavorable events, and the possible actions to take in order to effectively manage this risk, such as when it is appropriate to avoid, withdraw, switch, or adjust the dose of the medication. Conclusions The present evidence-based recommendations will improve the quality of psychiatric care in people with COVID-19, allowing an appropriate management of the medical condition without worsening the psychiatric condition and vice versa.

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 462-468
Author(s):  
Latika kothari ◽  
Sanskruti Wadatkar ◽  
Roshni Taori ◽  
Pavan Bajaj ◽  
Diksha Agrawal

Coronavirus disease 2019 (COVID-19) is a communicable infection caused by the novel coronavirus resulting in severe acute respiratory syndrome coronavirus 2 (SARS-CoV). It was recognized to be a health crisis for the general population of international concern on 30th January 2020 and conceded as a pandemic on 11th March 2020. India is taking various measures to fight this invisible enemy by adopting different strategies and policies. To stop the COVID-19 from spreading, the Home Affairs Ministry and the health ministry, of India, has issued the nCoV 19 guidelines on travel. Screening for COVID-19 by asking questions about any symptoms, recent travel history, and exposure. India has been trying to get testing kits available. The government of India has enforced various laws like the social distancing, Janata curfew, strict lockdowns, screening door to door to control the spread of novel coronavirus. In this pandemic, innovative medical treatments are being explored, and a proper vaccine is being hunted to deal with the situation. Infection control measures are necessary to prevent the virus from further spreading and to help control the current situation. Thus, this review illustrates and explains the criteria provided by the government of India to the awareness of the public to prevent the spread of COVID-19.


2020 ◽  
Vol 30 (1) ◽  
pp. 38030 ◽  
Author(s):  
Deivendran Kalirathinam ◽  
Raj Guruchandran ◽  
Prabhakar Subramani

The 2019 novel coronavirus officially named as coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization, has spread to more than 180 countries. The ongoing global pandemic of severe acute respiratory syndrome coronavirus, which causes COVID-19, spread to the United Kingdom (UK) in January 2020. Transmission within the UK was confirmed in February, leading to an epidemic with a rapid increase in cases in March. As on April 25- 2020, there have been 148,377 confirmed cases of COVID-19 in the UK and 20,319 people with confirmed infection have died. Survival of critically ill patients is frequently associated with significant functional impairment and reduced health-related quality of life. Early physiotherapy and community rehabilitation of COVID-19 patients has recently been identified as an essential therapeutic tool and has become a crucial evidence-based component in the management of these patients. This comprehensive narrative review aims to describe recent progress in the application of physiotherapy management in COVID 19 patients. Assessment and evidence- based treatment of these patients should include prevention, reduction of adverse consequences in immobilization, and long-term impairment sequelae. A variety of techniques and modalities of early physiotherapy in intensive care unit are suggested by clinical research. They should be applied according to the stage of the disease, comorbidities, and patient’s level of cooperation.


AAOHN Journal ◽  
2007 ◽  
Vol 55 (8) ◽  
pp. 321-325 ◽  
Author(s):  
Belinda J. McGrath

Childcare workers are exposed to several health and safety risks in their work environment, the most common being infectious diseases, musculoskeletal injuries, accidents, and occupational stress. Pregnant childcare workers have an additional risk of potential harm to the fetus. Occupational health nurses can work collaboratively with childcare workers to reduce these risks and provide workplace health promotion programs. This article explores the occupational health and safety issues for childcare workers and suggests health promotion strategies that could be implemented by occupational health nurses working in this arena.


2005 ◽  
Vol 2 (4) ◽  
pp. 453-458 ◽  
Author(s):  
Francesco Chiappelli ◽  
Paolo Prolo ◽  
Olivia S. Cajulis

Contemporary Western medicine has witnessed a fragmentation of our conceptualization of the medical endeavor into ‘traditional medicine’ and ‘non-traditional medicine’. The former is meant to refer to the Western medical tradition, the latter encompasses both ‘complementary’ and ‘alternative’ medical practices. Complementary medicine complements conventional medical treatments, and alternative modes of medical interventions are meant to replace traditional Western medicine. Evidence-based research must be directed at establishing the best available evidence in complementary and alternative medicine. This paper is the first of a set of four ‘lectures’ that reviews the process of evidence-based research, and discusses its implications and applications for the early decades of the 21st century. The purpose of this paper is to introduce the series by examining some of the historical and philosophical foundations of this research endeavor.


2021 ◽  
pp. 084653712110156
Author(s):  
Pejman Jabehdar Maralani ◽  
Anish Kapadia ◽  
Grace Liu ◽  
Felipe Moretti ◽  
Hournaz Ghandehari ◽  
...  

The use of magnetic resonance imaging (MRI) during pregnancy is associated with concerns among patients and health professionals with regards to fetal safety. In this work, the Canadian Association of Radiologists (CAR) Working Group on MRI in Pregnancy presents recommendations for the use of MRI in pregnancy, derived from literature review as well as expert panel opinions and discussions. The working group, which consists of academic subspecialty radiologists and obstetrician-gynaecologists, aimed to provide updated, evidence-based recommendations addressing safety domains related to energy deposition, acoustic noise, and gadolinium-based contrast agent use based on magnetic field strength (1.5T and 3T) and trimester scanned, in addition to the effects of sedative use and occupational exposure.


The Lancet ◽  
1996 ◽  
Vol 348 (9026) ◽  
pp. 540
Author(s):  
Ronald Bayer

2021 ◽  
Vol 51 (3) ◽  
pp. 264-270
Author(s):  
Simone E Taylor ◽  
◽  
David McD Taylor ◽  
Daisy Pisasale ◽  
Kyle Booth ◽  
...  

Introduction: The aim of this study was to describe the nature of regular medications taken by active comorbid scuba divers (having a declared medical comorbidity) and scuba divers and snorkellers who died following a diving incident. Methods: We undertook a retrospective, observational study from July to October, 2020. Data on 268 active comorbid divers were obtained through a 2013 survey of Divers Alert Network Asia-Pacific members. Data on 126 deceased scuba divers and 175 deceased snorkellers were obtained predominantly from 2001–2013 reports to Australian State Coronial Services. Results: The active comorbid divers were significantly older, less likely to be male, and more likely to be taking one or more medications than the two deceased subject groups (P < 0.001). Cardiovascular, endocrine and psychotropic medications accounted for 53.4%, 9.9% and 6.4% of all medications taken, respectively. Almost one tenth of the deceased divers took at least one psychotropic medication, a proportion significantly greater than the other groups (P = 0.01). Conclusions: Medication use among active comorbid divers is common which likely reflects their declared medical condition. Nevertheless, they appear to be diving relatively safely, often with conditions once thought to be absolute contradictions to scuba diving. The deceased divers took significantly more psychotropic medications. It is possible that their underlying psychological/psychiatric conditions rendered them more at risk of a diving incident. Increased vigilance for psychological conditions may need to be considered during diving medical examinations.


be supplemented by a statement of organization), monitor its implementation and evaluate its effectiveness. • The governing body will ensure that the policy is drawn to the attention of all staff. • The school will have clear procedures for identifying and controlling health and safety risks, and for reporting and dealing with irregularities. • There will be codes of practice for staff and pupils for the use of classrooms, general use areas and specialist areas, which will be shared with them, monitored and evaluated. • There will be adequate procedures for first aid in the event of accident and illness. • Certificates of inspection of equipment and resources will be maintained according to statutory and local requirements where appropriate. • Outdoor equipment will be checked on a regular basis for safety by the appropriate body. • The school will meet (or exceed) required standards and current codes of practice regarding escape in the event of fire. • Appropriate detailed guidance on health and safety issues regarding the buildings, grounds, fixtures and fittings will be provided in the staff handbook for all staff, and in guidance notes for temporary staff. • Appropriate detailed guidance on health and safety issues regarding the buildings, grounds, fixtures and fittings will be provided in the handbook for pupils and parents. • All seating will be appropriately sized and safe for its users. • Any vehicles used by school pupils or staff in the pursuit of their work will be checked for safety, and all relevant documents will be available for inspection by the appropriate committee or individual. • All staff driving pupils will have appropriate qualifications for the vehicle. • The costs of breakages and vandalism will be monitored on a . . . ly basis by the Environment Committee. • The Environment Committee will agree and monitor a policy on the conservation of energy within the buildings and grounds.

2002 ◽  
pp. 72-72

2021 ◽  
pp. 471-477
Author(s):  
Noah Samuels ◽  
Eran Ben-Arye

Pain is a common and often debilitating symptom in both oncology and non-cancer settings, with conventional medical treatments often limited by adverse effects. Integrative medicine provides non-conventional therapies in a conventional setting, offering an additional option for the treatment of symptoms, including pain. Clinical research supports modalities such as acupuncture, touch therapies, and mind–body medicine (yoga, meditation, music therapy, hypnosis, etc.) in the treatment of pain, most significantly when provided as an ‘add-on’ to conventional palliative and supportive care. The Society for Integrative Oncology’s evidence-based guidelines on the use of integrative medicine in patients with breast cancer include the treatment of pain and exacerbating factors such as anxiety and stress. These guidelines have been endorsed by the American Society for Clinical Oncology and are in keeping with those recommended by the National Comprehensive Cancer Network. This chapter examines the effectiveness of integrative medicine in the treatment of pain in both oncology and non-cancer settings. An open and effective collaboration is needed among integrative physicians, who understand both paradigms of care, and palliative care professionals. Ways in which this collaboration can be advanced and future directions for research in the treatment of pain in palliative care are discussed.


Author(s):  
Mary C. Zanarini

At baseline, borderline patients reported using high rates of outpatient treatment and more restrictive forms of treatment, such as inpatient psychiatric treatment. Over time, these rates have declined, particularly for more restrictive and costly forms of treatment. However, high rates of borderline patients remain in outpatient psychotherapy and continue taking standing medications in all major classes of psychotropic medications. Perhaps most concerning is that a substantial percentage of borderline patients have been treated with aggressive polypharmacy (three or more standing medications) despite the health consequences, such as obesity, and despite there being no empirical evidence for this common practice. Evidence-based psychosocial treatments are reviewed, and suggestions are made for treatment as usual.


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