scholarly journals Defining the relationship between Plasmodium vivax parasite rate and clinical disease

2015 ◽  
Vol 14 (1) ◽  
Author(s):  
Katherine E Battle ◽  
Ewan Cameron ◽  
Carlos A Guerra ◽  
Nick Golding ◽  
Kirsten A Duda ◽  
...  
2012 ◽  
Vol 18 (9) ◽  
pp. 1045-1047 ◽  
Author(s):  
Samuel D. Kim ◽  
Steve Vucic ◽  
Neil Mahant ◽  
Matthew C. Kiernan ◽  
Victor S.C. Fung

2004 ◽  
Vol 106 (4) ◽  
pp. 345-346
Author(s):  
Marina L. H. HONING ◽  
Coen D. A. STEHOUWER

The majority of clinical studies demonstrate that patients with hyperhomocysteinaemia have an increased risk of atherothrombotic events. However, there is a striking and poorly understood heterogeneity in the severity of clinical features in individuals with hyperhomocysteinaemia. This observation suggests that other factors must exist that modulate the relationship between hyperhomocysteinaemia and clinical disease. Therefore identifying factors that inhibit or enhance the vasculotoxic effects of homocysteine is important, as is elucidation of how homocysteine damages blood vessels. This comment discusses the study of Woodman and colleagues in this issue of Clinical Science in which they investigate the effects of hyperhomocysteinaemia on endothelial function.


Anaerobe ◽  
2013 ◽  
Vol 24 ◽  
pp. 109-116 ◽  
Author(s):  
Paul E. Carlson ◽  
Seth T. Walk ◽  
Alexandra E.T. Bourgis ◽  
Melissa W. Liu ◽  
Fatos Kopliku ◽  
...  

Author(s):  
Forman E. Siagian ◽  
Derilandry Isham ◽  
Ronny . ◽  
Muhammad Alfarabi ◽  
Sudung Nainggolan ◽  
...  

Background: Imported cases of malarial vivax also induce erythrocyte enlargement. The size of enlargement depend on the size of the parasite inside the cells. The aim of the study was to examine 20 slides of positive malaria vivax and seek for erythrocyte infected malaria and measure the size of enlarged cells and its shape. As a comparison, a number of normal erythrocyte also evaluated for its size and shape.Methods: This simple cross sectional design of microscope based study was conducted in Parasitology lab, Faculty of Medicine, Universitas Kristen Indonesia, Jakarta-Indonesia, from January to June of 2019. All data collected and further processed using SPSS™.Results: A total number of 982 erythrocyte infected with P. vivax were examined individually.  Those number consist of 243 immature trophozoite, 231 mature trophozoite, 251 micro-gametocyte, and 257 macrogametocyte. As a comparison also being examined 70 normal erythrocyte. Each erythrocyte infected with malaria vivax parasite enlarge to some extent, had irregular shape and the size varied based on the stage of the parasite inside the cells.Discussion: This enlarged erythrocyte is prone to cell sequestration and lysis, a condition that leads to anemia. Anemia affect not just the host but also the community. Proper management of malaria will reduce the burden to the community.Conclusions: Enlarged infected erythrocyte due to malaria vivax can cause anemia with effect to the host and also to the community.


Sign in / Sign up

Export Citation Format

Share Document