Scaffold strategies combined with mesenchymal stem cells in vaginal construction: a review

AbstractTissue engineering has provided new treatment alternatives for tissue reconstruction. Advances in the tissue engineering field have resulted in mechanical support and biological substitutes to restore, maintain or improve tissue/organs structures and functions. The application of tissue engineering technology in the vaginal reconstruction treatment can not only provide mechanical requirements, but also offer tissue repairing as an alternative to traditional approaches. In this review, we discuss recent advances in cell-based therapy in combination with scaffolds strategies that can potentially be adopted for gynaecological transplantation.

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A Feasibility of Useful Cell-Based Therapy by Bone Regeneration with Deciduous Tooth Stem Cells, Dental Pulp Stem Cells, or Bone-Marrow-Derived Mesenchymal Stem Cells for Clinical Study Using Tissue Engineering Technology

Tissue Engineering Part A ◽

10.1089/ten.tea.2009.0732 ◽

2010 ◽

Vol 16 (6) ◽

pp. 1891-1900 ◽

Cited By ~ 70

Author(s):

Yoichi Yamada ◽

Sayaka Nakamura ◽

Kenji Ito ◽

Takayuki Sugito ◽

Ryoko Yoshimi ◽

...

Keyword(s):

Tissue Engineering ◽

Stem Cells ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Clinical Study ◽

Bone Regeneration ◽

Dental Pulp ◽

Engineering Technology ◽

Cell Based Therapy ◽

Tissue Engineering Technology

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Smurf1-targeting miR-19b-3p-modified BMSCs combined PLLA composite scaffold to enhance osteogenic activity and treat critical-sized bone defects

Biomaterials Science ◽

10.1039/d0bm01251c ◽

2020 ◽

Vol 8 (21) ◽

pp. 6069-6081

Author(s):

Ao Xiong ◽

Yijun He ◽

Liang Gao ◽

Guoqing Li ◽

Jian Weng ◽

...

Keyword(s):

Tissue Engineering ◽

Composite Scaffold ◽

Biological Materials ◽

Bone Defects ◽

Engineering Technology ◽

Osteogenic Activity ◽

The Past ◽

Seed Cells ◽

Tissue Engineering Technology

Over the past few years, tissue-engineering technology provided a new direction for bone defects therapy, which involved developing applicable biological materials composite with seed cells to repair bone defects tissue.

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DEVELOPMENTAL STATUS AND PERSPECTIVES FOR TISSUE ENGINEERING IN UROLOGY

NATURE AND SCIENCE ◽

10.36719/2707-1146/12/5-13 ◽

2021 ◽

Vol 12 (07) ◽

pp. 5-13

Author(s):

Elcin Nizami Huseyn ◽

Keyword(s):

Tissue Engineering ◽

Biological Materials ◽

Organ Damage ◽

Biological Tissues ◽

Tissue Cell ◽

Sperm Cells ◽

Engineering Technology ◽

The Future ◽

Tissue Engineering Technology

Tissue engineering technology and tissue cell-based stem cell research have made great strides in treating tissue and organ damage, correcting tissue and organ dysfunction, and reducing surgical complications. In the past, traditional methods have used biological substitutes for tissue repair materials, while tissue engineering technology has focused on merging sperm cells with biological materials to form biological tissues with the same structure and function as their own tissues. The advantage is that tissue engineering technology can overcome donors. Material procurement restrictions can effectively reduce complications. The aim of studying tissue engineering technology is to find sperm cells and suitable biological materials to replace the original biological functions of tissues and to establish a suitable in vivo microenvironment. This article mainly describes the current developments of tissue engineering in various fields of urology and discusses the future trends of tissue engineering technology in the treatment of complex diseases of the urinary system. The results of the research in this article indicate that while the current clinical studies are relatively few, the good results from existing animal model studies indicate good prospects of tissue engineering technology for the treatment of various urinary tract diseases in the future. Key words: Tissue engineering, kidney, ureter, bladder, urethra

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Biofunctionalization of decellularized porcine aortic valve with OPG-loaded PCL nanoparticles for anti-calcification

RSC Advances ◽

10.1039/c9ra00408d ◽

2019 ◽

Vol 9 (21) ◽

pp. 11882-11893

Author(s):

Yang Li ◽

Yu Zhang ◽

Jing-Li Ding ◽

Ji-Chun Liu ◽

Jian-Jun Xu ◽

...

Keyword(s):

Tissue Engineering ◽

Controlled Release ◽

Aortic Valve ◽

Drug Loading ◽

Biological Factor ◽

Engineering Technology ◽

Loading System ◽

Tissue Engineering Technology

A novel composite valve with controlled release OPG was prepared by introducing tissue engineering technology and nano drug-loading system to introduce anti-calcification biological factor OPG on the decellularized valve.

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A Bibliometric Review of Artificial Extracellular Matrices Based on Tissue Engineering Technology Literature: 1990 through 2019

Materials ◽

10.3390/ma13132891 ◽

2020 ◽

Vol 13 (13) ◽

pp. 2891

Author(s):

Pilar Simmons ◽

Taylor McElroy ◽

Antiño R. Allen

Keyword(s):

Tissue Engineering ◽

Therapeutic Option ◽

Extracellular Matrices ◽

Engineering Technology ◽

Network Analyses ◽

Bibliometric Review ◽

Artificial Extracellular Matrix ◽

Tissue Engineering Technology

Artificial extracellular matrices (aECMs) are an extension of biomaterials that were developed as in-vitro model environments for tissue cells that mimic the native in vivo target tissues’ structure. This bibliometric analysis evaluated the research productivity regarding aECM based on tissue engineering technology. The Web of Science citation index was examined for articles published from 1990 through 2019 using three distinct aECM-related topic sets. Data were also visualized using network analyses (VOSviewer). Terms related to in-vitro, scaffolds, collagen, hydrogels, and differentiation were reoccurring in the aECM-related literature over time. Publications with terms related to a clinical direction (wound healing, stem cells, artificial skin, in-vivo, and bone regeneration) have steadily increased, as have the number of countries and institutions involved in the artificial extracellular matrix. As progress with 3D scaffolds continues to advance, it will become the most promising technology to provide a therapeutic option to repair or replace damaged tissue.

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