scholarly journals A prospective surveillance study for multidrug-resistant bacteria colonization in hospitalized patients at a Thai University Hospital

Author(s):  
Pinyo Rattanaumpawan ◽  
Chatiros Choorat ◽  
Kanchanaporn Takonkitsakul ◽  
Teerawit Tangkoskul ◽  
Chakrapong Seenama ◽  
...  
2016 ◽  
Vol 10 (33) ◽  
pp. 1328-1336 ◽  
Author(s):  
Hecini-Hannachi Abla ◽  
Bentchouala Chafia ◽  
Lezzar Abdesselam ◽  
Laouar Houcine ◽  
Benlabed Kaddour ◽  
...  

2001 ◽  
Vol 22 (02) ◽  
pp. 109-111 ◽  
Author(s):  
Gwenaëlle M. Vidal-Trecan ◽  
Natalie Delamare ◽  
Stephanie Tcherny-Lessenot ◽  
Jacqueline Lamory ◽  
François Baudin ◽  
...  

AbstractIsolation practices in a university hospital were analyzed for 137 patients with multidrug-resistant bacteria. Isolation was ordered in writing by physicians for 40% and instituted by nurses for 60%; 74% were isolated. Compliance depended on physician ordering in writing (odds ratio, 36.3; 95% confidence interval, 4.8-274.9). Nurses complied best with hand washing.


2015 ◽  
Vol 43 (9) ◽  
pp. 960-964 ◽  
Author(s):  
Romain Picot-Guéraud ◽  
Pierre Batailler ◽  
Yvan Caspar ◽  
Aurélie Hennebique ◽  
Marie-Reine Mallaret

2001 ◽  
Vol 22 (02) ◽  
pp. 109-111 ◽  
Author(s):  
Gwenaëlle M. Vidal-Trecan ◽  
Natalie Delamare ◽  
Stephanie Tcherny-Lessenot ◽  
Jacqueline Lamory ◽  
François Baudin ◽  
...  

Abstract Isolation practices in a university hospital were analyzed for 137 patients with multidrug-resistant bacteria. Isolation was ordered in writing by physicians for 40% and instituted by nurses for 60%; 74% were isolated. Compliance depended on physician ordering in writing (odds ratio, 36.3; 95% confidence interval, 4.8-274.9). Nurses complied best with hand washing.


2011 ◽  
Vol 16 (8) ◽  
Author(s):  
P Gaibani ◽  
S Ambretti ◽  
A Berlingeri ◽  
F Gelsomino ◽  
A Bielli ◽  
...  

The first case of carbapenemase-producing Enterobacteriaceae in Italy was reported in 2009. We performed a study over a period of seven months in 2010 to survey the circulation of Klebsiella pneumoniae carbapenemases (KPC) in a 1,500-bed university hospital in northern Italy and report the presence and rapid increase of these multidrug-resistant bacteria. The results raise a major concern about these pathogens and demonstrate the urgent need for infection control and antibiotic stewardship programmes.


Author(s):  
Richard E Nelson ◽  
David Hyun ◽  
Amanda Jezek ◽  
Matthew H Samore

Abstract Background This study reports estimates of the healthcare costs, length of stay, and mortality associated with infections due to multidrug-resistant bacteria among elderly individuals in the United States. Methods We conducted a retrospective cohort analysis of patients aged ≥65 admitted for inpatient stays in the Department of Veterans Affairs healthcare system between 1/2007–12/2018. We identified those with positive cultures for multidrug-resistant bacteria and matched each infected patient to ≤10 control patients. We then performed multivariable regression models to estimate the attributable cost and mortality due to the infection. We also constructed multistate models to estimate the attributable length of stay due to the infection. Finally, we multiplied these pathogen-specific attributable cost, length of stay, and mortality estimates by national case counts from hospitalized patients in 2017. Results Our cohort consisted of 87 509 patients with infections and 835 048 matched controls. Costs were higher for hospital-onset invasive infections, with attributable costs ranging from $22 293 (95% confidence interval: $19 101–$24 485) for methicillin-resistant Staphylococcus aureus (MRSA) to $57 390 ($34 070–$80 710) for carbapenem-resistant (CR) Acinetobacter. Similarly, for hospital-onset invasive infections, attributable mortality estimates ranged from 14.2% (12.2–16.2%) for MRSA to 24.1% (12.1–36.0%) for CR Acinetobacter. The aggregate cost of these infections was an estimated $1.9 billion ($1.3 billion–$2.5 billion) with 11 852 (8719–14 985) deaths and 448 224 (354 513–541 934) inpatient days in 2017. Conclusions Efforts to prevent these infections due to multidrug-resistant bacteria could save a significant number of lives and healthcare resources.


2021 ◽  
Vol 22 (7) ◽  
Author(s):  
Abdelaziz Ed-Dra ◽  
Fouzia Rhazi Filali ◽  
Vittorio Lo Presti ◽  
Badr Zekkori ◽  
Luca Nalbone ◽  
...  

Abstract. Ed-Dra A, Filali FR, Presti VL, Zekkori B, Nalbone L, Elsharkawy ER, Bentayeb A, Giarrtana F. 2021. Effectiveness of essential oil from the Artemisia herba-alba aerial parts against multidrug-resistant bacteria isolated from food and hospitalized patients. Biodiversitas 22: 2995-3005. The World Health Organization has sounded the warning on the diffusion of multidrug resistance (MDR) bacteria, requiring solutions and alternatives to solve the therapeutic failure that may occur. This study aims to evaluate the antioxidant activity and bactericidal effectiveness against MDR bacteria of Artemisia herba-alba essential oil (A-EO) collected from semi-arid region of Morocco. Chemical composition of the A-EO was determined by Gas Chromatography-Flame Ionisation Detector and Gas Chromatography-Mass Spectrometry, while the antioxidant activity was performed by DPPH scavenging activity and ?-carotene bleaching assay. Antibacterial activity of A-EO, performed by disc diffusion assay and broth dilution method, was tested against: four MDR strains (Escherichia coli, Staphylococcus aureus, Salmonella Typhimurium and Enterococcus faecalis) isolated from food matrices, two (Klebsiella pneumonia and Pseudomonas aeruginosa) from hospitalized patients, and Escherichia coli ATCC 25922 as reference strain. Davanone was the main compound among the 17 identified. An antioxidant activity with IC50 of 1.13±0.02 mg/mL, EC50 of 2.12±0.05 mg/mL and RC50 of 0.87±0.02 mg/mL was observed. A weak activity against P. aeruginosa was observed, while it was intermediate or high against the other bacteria. This study confirms that A-EO could be a suitable alternative to antibiotics in the infection treatment related to MDR bacteria.


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