scholarly journals Rapid increase of carbapenemase-producing Klebsiella pneumoniae strains in a large Italian hospital: surveillance period 1 March – 30 September 2010

2011 ◽  
Vol 16 (8) ◽  
Author(s):  
P Gaibani ◽  
S Ambretti ◽  
A Berlingeri ◽  
F Gelsomino ◽  
A Bielli ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Infection Control ◽  
Multidrug Resistant ◽  
Northern Italy ◽  
University Hospital ◽  
Resistant Bacteria ◽  
Surveillance Period ◽  
Multidrug Resistant Bacteria ◽  
First Case ◽  
Klebsiella Pneumoniae Carbapenemases

The first case of carbapenemase-producing Enterobacteriaceae in Italy was reported in 2009. We performed a study over a period of seven months in 2010 to survey the circulation of Klebsiella pneumoniae carbapenemases (KPC) in a 1,500-bed university hospital in northern Italy and report the presence and rapid increase of these multidrug-resistant bacteria. The results raise a major concern about these pathogens and demonstrate the urgent need for infection control and antibiotic stewardship programmes.

Multidrug-Resistant Bacteria Infection Control: Study of Compliance With Isolation Precautions in a Paris University Hospital

2001 ◽  
Vol 22 (02) ◽  
pp. 109-111 ◽  
Author(s):  
Gwenaëlle M. Vidal-Trecan ◽  
Natalie Delamare ◽  
Stephanie Tcherny-Lessenot ◽  
Jacqueline Lamory ◽  
François Baudin ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Infection Control ◽  
Odds Ratio ◽  
Multidrug Resistant ◽  
Hand Washing ◽  
University Hospital ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Control Study

AbstractIsolation practices in a university hospital were analyzed for 137 patients with multidrug-resistant bacteria. Isolation was ordered in writing by physicians for 40% and instituted by nurses for 60%; 74% were isolated. Compliance depended on physician ordering in writing (odds ratio, 36.3; 95% confidence interval, 4.8-274.9). Nurses complied best with hand washing.

Multidrug-Resistant Bacteria Infection Control: Study of Compliance With Isolation Precautions in a Paris University Hospital

2001 ◽  
Vol 22 (02) ◽  
pp. 109-111 ◽  
Author(s):  
Gwenaëlle M. Vidal-Trecan ◽  
Natalie Delamare ◽  
Stephanie Tcherny-Lessenot ◽  
Jacqueline Lamory ◽  
François Baudin ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Infection Control ◽  
Odds Ratio ◽  
Multidrug Resistant ◽  
Hand Washing ◽  
University Hospital ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Control Study

Abstract Isolation practices in a university hospital were analyzed for 137 patients with multidrug-resistant bacteria. Isolation was ordered in writing by physicians for 40% and instituted by nurses for 60%; 74% were isolated. Compliance depended on physician ordering in writing (odds ratio, 36.3; 95% confidence interval, 4.8-274.9). Nurses complied best with hand washing.

scholarly journals Multidrug-resistant bacteria isolated from patients hospitalized in Intensive Care Unit in University Hospital of Constantine, Algeria (2011 - 2015)

2016 ◽  
Vol 10 (33) ◽  
pp. 1328-1336 ◽  
Author(s):  
Hecini-Hannachi Abla ◽  
Bentchouala Chafia ◽  
Lezzar Abdesselam ◽  
Laouar Houcine ◽  
Benlabed Kaddour ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Multidrug Resistant ◽  
University Hospital ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria

scholarly journals Next-Generation Epidemiology: Using Real-Time Core Genome Multilocus Sequence Typing To Support Infection Control Policy

2016 ◽  
Vol 54 (12) ◽  
pp. 2850-2853 ◽  
Author(s):  
John P. Dekker ◽  
Karen M. Frank
Keyword(s):  
Infection Control ◽  
Real Time ◽  
Core Genome ◽  
Hospital Setting ◽  
Control Policy ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Substantial Morbidity ◽  
Multilocus Sequencing

Multidrug-resistant bacteria are responsible for substantial morbidity and mortality worldwide. Tracking the nosocomial spread of resistant bacteria is critical to infection control. Mellmann et al. (J. Clin. Microbiol. 54:2874–2881, 2016, http://dx.doi.org/10.1128/JCM.00790-16 ) have described prospective whole-genome sequencing with core genome multilocus sequencing typing (cgMLST) analysis for real-time surveillance and have addressed the practical aspects of implementing this type of operation in the hospital setting.

scholarly journals Bacteremia caused by multidrug-resistant bacteria in a French university hospital center: 3 years of collection

2015 ◽  
Vol 43 (9) ◽  
pp. 960-964 ◽  
Author(s):  
Romain Picot-Guéraud ◽  
Pierre Batailler ◽  
Yvan Caspar ◽  
Aurélie Hennebique ◽  
Marie-Reine Mallaret
Keyword(s):  
Multidrug Resistant ◽  
University Hospital ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Hospital Center

scholarly journals Successful Treatment of Klebsiella pneumoniae NDM Sepsis and Intestinal Decolonization with Ceftazidime/Avibactam Plus Aztreonam Combination in a Patient with TTP Complicated by SARSCoV-2 Nosocomial Infection

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 424
Author(s):  
Francesco Perrotta ◽  
Marco Paolo Perrini
Keyword(s):  
Klebsiella Pneumoniae ◽  
Therapeutic Option ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Carbapenem Resistant ◽  
Global Concern ◽  
Rectal Colonization ◽  
Hospital Acquired ◽  
Carbapenem Resistant Enterobacteriaceae

Carbapenem-resistant Enterobacteriaceae (CRE) are a serious public health threat. Infections due to these organisms are associated with significant morbidity and mortality. Among them, metallo-β-lactamases (MBLs)-producing Klebsiella pneumoniae are of global concern today. The ceftazidime/avibactam combination and the ceftazidime/avibactam + aztreonam combination currently represent the most promising antibiotic strategies to stave off these kinds of infections. We describe the case of a patient affected by thrombotic thrombocytopenic purpura (TTP) admitted in our ICU after developing a hospital-acquired SarsCoV2 interstitial pneumonia during his stay in the hematology department. His medical conditions during his ICU stay were further complicated by a K. Pneumoniae NDM sepsis. To our knowledge, the patient had no risk factors for multidrug-resistant bacteria exposure or contamination during his stay in the hematology department. During his stay in the ICU, we treated the sepsis with a combination therapy of ceftazidime/avibactam + aztreonam. The therapy solved his septic state, allowing for a progressive improvement in his general condition. Moreover, we noticed that the negativization of the hemocultures was also associated to a decontamination of his known rectal colonization. The ceftazidime/avibactam + aztreonam treatment could not only be a valid therapeutic option for these kinds of infections, but it could also be considered as a useful tool in selected patients’ intestinal decolonizations.

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