Abstract
Background: Tuberculosis (TB) is the most frequent life-threatening infection and a common cause of death for people living with HIV (PLHIV).The influence of TB and HIV infection has enhanced the magnitude of both epidemics. IPT is one of the several key interventions recommended by the world health organization (WHO) for the prevention of TB in patients infected with HIV. Hence, the present study aimed to determine the IPT utilization rate and to explore the determinant factors among PLHIV under follow-up, Health care providers (HCP’s) and TB/HIV coordinators working in Jimma University Specialized Hospital (JUSH) ART clinic, Ethiopia. Methods: An Institution based cross-sectional study was conducted in JUSH ART clinic, Oromia region, Ethiopia. The target groups were enrolled by a systematic sampling technique from the registered medical records of JUSH HIV care. Semi-structured questioners and in-depth interviews were designed for quantitative analysis from PLHIV, HCP’s and TB/HIV coordinators working in JUSH, ART clinic. All statistical analysis was compiled by Epi data 3.1 and SPSS 20. Results: The overall estimated IPT utilization rate in JUSH ART clinic was 59.2%.Demographic and clinical factors are not significant, but ethnicity was highly significant with IPT use in PLHIV. All respondents, HCP’s and TB/HIV coordinators were interviewed on identifying the factors and barriers that increase the utilization of IPT. The results of in-depth interviews are grouped into three core categories as patient perceptions, HCP’s and TB/HIV coordinator perspectives. Discussion and conclusion:PLHIV, HCP’s and TB/HIV coordinators suggested their overall response as periodic counseling for target groups, educating the benefits of IPT and increasing public awareness on TB prophylaxis in PLHIV. Higher attention should be provided in linking all HIV patients to the nearest health facilities for receiving free service packages and medical care. Administrative managers could improve the capacity building by increasingthe number of health care professionals, maintaining data base on patient records and continuous supply of pyridoxine and IPT for all PLHIV. HCP’s and TB/HIV coordinators responded that disclosure to the patient families and occupational independence will increase the acceptance and implementation of IPT in large scale.
Emergence of high drug resistant bacterial isolates from patients with health care associated infections at Jimma University medical center: a cross sectional study
