Relationship between risk markers for cardiovascular disease and peri-implant diseases

Abstract Background The aim of this paper is to explore the serum biochemical parameters also known as risk markers for cardiovascular system, in individuals who have received dental implant treatment, and to reveal risk factors for peri-implant diseases. Methods The study included 58 subjects with peri-implantitis, 49 subjects with peri-implant mucositis, and 49 healthy subjects. All the subjects were assessed in terms of both peri-implant clinical parameters—probing depth (PD), bleeding on probing (BOP), the type of prosthesis, gingival index (GI), keratinized mucosa width (KMW), and plaque index (PI)—and serum biochemical parameters (e.g., LDL cholesterol, HDL cholesterol, triglyceride, total cholesterol, vitamin D, uric acid, white blood cell (WBC), neutrophil, hemoglobin (Hb), and platelet counts). Results KMW was the lowest in the peri-implantitis group. Compared with the other groups, the peri-implantitis group showed significantly higher levels of triglyceride, uric acid, and WBC. The peri-implantitis group had the lowest level of vitamin D. Triglyceride and uric acid levels had positive correlations with peri-implant clinical parameters. Conclusion High levels of triglyceride and uric acid may pose a risk for both peri-implant diseases and cardiovascular diseases. Prior to dental implant surgery, patients’ serum biochemical parameters should be checked.

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Effect of graded levels of nucleotide supplementation on certain serum biochemical parameters in Japanese quails

Indian Journal of Animal Research ◽

10.18805/ijar.8411 ◽

2016 ◽

Author(s):

S. Prakash ◽

Jyoti Palod ◽

R. K. Sharma ◽

S. K. Singh

Keyword(s):

Biochemical Parameters ◽

Protein Profile ◽

Hdl Cholesterol ◽

Serum Glucose ◽

Serum Biochemical Parameters ◽

Treatment Groups ◽

Japanese Quails ◽

Randomized Design ◽

Serum Biochemical ◽

G Ratio

A trial was conducted for a period of 6 weeks to evaluate the effect of graded levels of nucleotide supplementation on serum biochemical parameters in Japanese quails. In the trial, 3 day old Japanese quail chicks were randomly distributed in completely randomized design into 4 treatment groups each with 3 replicates of 10 Japanese quails. The Japanese quails of treatment groups T1, T2, T3 and T4 were provided feed containing 0, 0.5, 1.0 and 1.5 per cent nucleotide respectively for a period of six weeks. At the end of experiment blood samples were collected for study of serum-biochemical parameters. The results indicated that decreased serum glucose, serum cholesterol and LDL cholesterol and increased HDL cholesterol was noticed in nucleotide supplemented groups at higher levels. Protein profile showed significant improvement in total protein, albumin and globulin while A/G ratio revealed no effect of supplementation. Serum creatinine and SGPT contents showed non-significance whereas, serum uric acid and SGOT contents were significantly (P<0.05) reduced in nucleotide supplemented groups of quails. It is concluded that nucleotide supplementation improves serum biochemical parameters without affecting liver and kidney functions.

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Tracking the development of serum biochemical parameters in two laying hen strains – a comparative study

Archives Animal Breeding ◽

10.5194/aab-49-593-2006 ◽

2006 ◽

Vol 49 (6) ◽

pp. 593-606 ◽

Cited By ~ 1

Author(s):

J. Gyenis ◽

Z. Sütő ◽

R. Romvári ◽

P. Horn

Keyword(s):

Body Composition ◽

Comparative Study ◽

Biochemical Parameters ◽

Hdl Cholesterol ◽

Laying Hen ◽

Total Serum ◽

Composition Analysis ◽

Dry Matter Content ◽

Serum Biochemical Parameters ◽

Serum Biochemical

Abstract. A follow-up, comparative study was designed for the description of differences between two divergent laying hen strains, a Leghorn type and a medium heavy body (MHB) genotype (Hy-Line Brown), in chemical body composition and serum biochemical parameters determined at 3, 4, 6, 8, 10, 12, 14, 18, 20, 25, 30, 52 and 72 weeks of age; each time 5 birds of both genotypes were analysed and exterminated for body composition analysis. Resulting from the genotype-associated differences, the bodyweight of the populations differed from week 20 on. In the chemical body composition dry matter content was similar, while crude protein was higher on weeks 3, 8, 10, and after 18 weeks in the Leghorns. Crude fat content was higher in the brown birds (weeks 8, 10, 25, 30). Total serum protein and albumin showed slightly increasing trends, while serum creatinine concentration showed a downward trend in both genotypes, the MHB birds having higher values. Triglyceride concentration showed a drastic step-up at 17 weeks by changing to the pre-layer diet, coupled with marked between-genotype differences. This quick increase was matched by concentration drops in total and HDL cholesterol, the serum HDL cholesterol of Leghorns being always lower. Sodium concentration showed an increasing tendency with body DM content (R2=0.914, P<0.001, n=115). The Leghorns tended to show minimally higher Ca concentrations. The γ-GT activity was always higher in MHB birds, indicating a less effective hepatic adaptation to the peak production. Applying discriminant analysis to classify the genotypes, 94.4% of the original grouped cases was correctly classified, using all variables.

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Evaluation of Phyllanthus amarus leaf meal for hepato nephro-protective potentials in broiler chickens

Journal of Veterinary and Biomedical Sciences ◽

10.36108/jvbs/1202.30.0141 ◽

2021 ◽

Vol 3 (1) ◽

pp. 126-135

Author(s):

Cyprian Robinson Unigwe

Keyword(s):

Uric Acid ◽

Biochemical Parameters ◽

Broiler Chickens ◽

Dependent Manner ◽

Phyllanthus Amarus ◽

Serum Biochemical Parameters ◽

Leaf Meal ◽

Liver And Kidney ◽

Serum Biochemical ◽

Dose Dependent

Phyllanthus amarus is an important medicinal plant that is widely distributed in all tropical and subtropical regions of the planet and has the ability to prevent and treat several human and animal diseases but has been associated with pathological defects on various organs on dose-dependent pattern. This study was carried out to evaluate Phyllanthus amarus leaf meal (PALM) for hepato-nephro-protective potentials in broiler chickens. One hundred and twenty (120) day old marshal broiler chickens were used for the experiment that lasted for 56 days. The birds were randomly allotted to five treatments of T0 (control, no PALM), T1 (2.5g/kg PALM), T2 (5.0g/kg PALM), T3 (7.5g/kg PALM) and T4 (10g/kg PALM) in a complete randomized design (CRD). Each treatment was replicated thrice with 8 birds per replicate. The birds were fed with commercial Top® feed and water was given ad-libitum. At the end of the experiment, blood was aseptically collected via venipuncture from a randomly selected bird per replicate to determine the serum biochemical parameters and later was humanely sacrificed for organs harvest. The liver and kidney were carefully dissected out and fixed in buffered 10% formalin for histological study. The biochemical data were subjected to analysis of variance (ANOVA) and statistical difference in means was separated using Duncan’s Multiple Range Test. The histo-pathological slides were interpreted by experts. ALT for T1 – T4 were statistically similar but differed significantly (P<0.05) from T1 . The ALP, however, showed T2 – T4 differing significantly (P<0.05) from T0 and T1 . The uric acid was highest in T4 and differed significantly (P<0.05) from other groups. The urea was highest in quantity in T3 and T4 and as well differed significantly (P<0.05) from other treatments. Therefore, the results showed significant differences (P<0.05) across treatment groups except for AST. PALM gradually increased the ALT, ALP, uric acid and urea in a dose dependent manner across treatments except urea that slightly decreased at T4 . The findings indicated that the PALM had varied time and dose dependent pathological effects on the liver and kidney of treated groups. It can therefore be concluded that PALM enhances serum biochemical parameters and has deleterious effects on the cyto-architecture of liver and kidney. It is recommended that PALM (crude) up to 2.5 g/kg should not be administered protractedly in chickens since it could constitute damage to visceral organs.

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