Predictors of Psychiatric Morbidity in Cancer Patients

1994 ◽  
Vol 165 (5) ◽  
pp. 593-598 ◽  
Author(s):  
Judy Harrison ◽  
Peter Maguire
Keyword(s):  
Risk Factors ◽  
Cancer Patients ◽  
Psychiatric Morbidity ◽  
Significant Proportion ◽  
Cross Sectional Study ◽  
Future Research ◽  
Cross Sectional ◽  
Appropriate Treatment ◽  
Study Designs ◽  
Patients Experience

BackgroundA significant proportion of cancer patients experience psychiatric morbidity in association with diagnosis and treatment. If this morbidity is to be reduced, a better understanding is needed of the factors which influence adjustment to cancer.MethodA review of the literature was carried out to explore those factors associated with poor psychological adjustment to cancer. These are described under four headings: characteristics of the patient; disease and treatment variables; the interaction between patient and illness; and environmental factors.ResultsA number of risk factors for psychiatric morbidity can be identified from each of the four areas. Methodological limitations are highlighted, in particular the preponderance of cross-sectional study designs.ConclusionsIncreased awareness of the risk factors for psychiatric morbidity should lead to earlier detection and more appropriate treatment. Future research should focus on those risk factors which are potentially modifiable.

scholarly journals Prevalensi Infeksi Clostridium difficile Pada Pasien Neutropenia dengan Kanker

Medicinus ◽  
2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Andree Kurniawan
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Cancer Patients ◽  
Immunocompromised Patient ◽  
Hematologic Malignancy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Multiple Risk Factors ◽  
Secondary Referral Hospital

<p><em>Clostridium difficile</em> (<em>C. difficile</em>) infection mostly found in immunocompromised patient. Most of the patients with neutropenia had hematologic malignancy and come with multiple risk factors for <em>C. difficile</em> infection. The aim of this study is to know the prevalence and characteristic of <em>C. difficile</em> infections in cancer neutropenia patients. This cross-sectional study was done in secondary referral hospital in suburban Karawaci, Tangerang, Banten, Indonesia from June 2014 until Mei 2015. Adult cancer patients hospitalized with neutrophil count less than 1500 10<sup>6</sup> cell/L were included. All patients were checked for antigen and toxin <em>C. difficile</em> in faeces. From 25 patients were evaluated for <em>C. difficile</em> infection in neutropenia. <em>C. difficile</em> antigen only found in one patient or 4% sample.</p><p><strong>Key words: <em>C. difficile</em>, cancer, neutropenia</strong></p>

scholarly journals Waterpipe Smoking among Bladder Cancer Patients: A Cross-Sectional Study of Lebanese and Jordanian Populations

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Elio Jabra ◽  
Amal Al-Omari ◽  
Fadi Haddadin ◽  
Walid Alam ◽  
Khawlah Ammar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bladder Cancer ◽  
Occupational Exposure ◽  
Cancer Patients ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
Significant Finding ◽  
Waterpipe Smoking ◽  
Sectional Study ◽  
Cross Sectional

Background. Bladder cancer (BC) is the second most reported cancer in Lebanon and the fifth in Jordan. Its risk factors are mainly smoking and occupational exposure to aromatic amines. In these countries where smoking and bladder cancer are highly prevalent, the role of waterpipe smoking (WPS) in bladder cancer is less investigated. We aim to compare two sets of patients between Lebanon and Jordan, focusing on their smoking habits, WP use, occupational exposure, and the grade/invasiveness of their bladder cancer. Methods. This is a cross-sectional study that compares the smoking culture between two sets of populations with bladder cancer, from two different countries. We recruited 274 bladder cancer patients over the 18 years of age at the American University of Beirut Medical Center (AUBMC), and 158 bladder cancer patients over the age of 18 years at the King Hussein Cancer Center (KHCC). Results. 7.7% of Lebanese patients had significantly more positive family history of bladder cancer compared to 13.9% of Jordanian patients ( p = 0.045 ). Another significant finding is that the majority of Lebanese patients 70.7% reported being frequently exposed to secondhand smoking, mainly cigarettes, versus only 48.6% of Jordanian patients ( p < 0.001 ). The increasing smoking trend among Lebanese females is remarkably the highest in the region, which contributed to the overall increase in smoking rates in the country. 17.1% of the Lebanese smoking patients are mainly but not exclusively WP smokers of which 6.3% are daily WP smokers, similarly 17.1% of the Jordanian patients of which 3.2% are daily WP smokers. There were 71.5% of Lebanese patients who had a noninvasive BC versus 40% of Jordanian patients ( p < 0.001 ), and more than one-third reported an occupational exposure to one of the risk factors of BC in both groups. Conclusions. Bladder cancer incidence is on the rise in both Jordan and Lebanon along with different smoking types. It is necessary to impose prevention policies to prevent and control the high smoking prevalence. Bladder cancer invasiveness is higher in Jordan compared to universal data.

Prevalence and risk factors of medication-related osteonecrosis of the jaw in osteoporotic and breast cancer patients: a cross-sectional study

2019 ◽  
Vol 28 (5) ◽  
pp. 2265-2271 ◽  
Author(s):  
Ana Laura Soares ◽  
Sérgio Simon ◽  
Luiz Henrique Gebrim ◽  
Afonso Celso P. Nazário ◽  
Marise Lazaretti-Castro
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Osteonecrosis Of The Jaw ◽  
Breast Cancer Patients ◽  
Sectional Study ◽  
Cross Sectional

Leishmania infantum: illness, transmission profile and risk factors for asymptomatic infection in an endemic metropolis in Brazil

Parasitology ◽  
2016 ◽  
Vol 144 (4) ◽  
pp. 546-556 ◽  
Author(s):  
LETÍCIA HELENA DOS SANTOS MARQUES ◽  
IARA CAIXETA MARQUES DA ROCHA ◽  
ILKA AFONSO REIS ◽  
GISELE MACEDO RODRIGUES DA CUNHA ◽  
EDWARD OLIVEIRA ◽  
...  
Keyword(s):  
Risk Factors ◽  
Leishmania Infantum ◽  
Disease Incidence ◽  
Significant Proportion ◽  
Cross Sectional Study ◽  
Asymptomatic Infection ◽  
Infection Prevalence ◽  
Prevalence Rates ◽  
Cross Sectional ◽  
Relative Risks

SUMMARYTo evaluate the distribution of asymptomatic infection by Leishmania infantum in a metropolis in Brazil with different relative risks (RRs) for disease and risk factors associated with the infection, an ecological study was conducted using a Bayesian approach to estimate the RR of human visceral leishmaniasis (HVL) based on cases between 2008 and 2011. The areas were categorized and selected according to disease incidence: low (area-1), medium (area-2) and high (area-3). Cross-sectional study enrolling 935 children was used to estimate the prevalence of infection by L. infantum. Volunteers from these three areas were tested for L. infantum infection by ELISA (rK39 and soluble antigens). Infection prevalence rates were estimated and compared with the RR of disease. Multilevel logistic regression model evaluated the relationship between infection and the analysed variables. The RR of HVL was distributed heterogeneously in the municipality. The infection prevalence rates were: 34·9% in area-1; 29·3% in area-2; and 33·6% in area-3, with no significant differences between these areas. The variables ‘Presence of backyards in the neighbourhood’ and ‘Younger children’ were associated with L. infantum infection. We conclude that infection by L. infantum affects a significant proportion of the infant population regardless of the RR of disease.

The Relationship Between Authenticity and Death Anxiety in Cancer Patients

2021 ◽  
pp. 003022282199760
Author(s):  
Faezeh Nazari ◽  
Zohreh Khoshnood ◽  
Parvin Mangolian Shahrbabaki
Keyword(s):  
Cancer Patients ◽  
Death Anxiety ◽  
Death And Dying ◽  
Care Program ◽  
Cross Sectional Study ◽  
Patient Death ◽  
Cross Sectional ◽  
The Many ◽  
Patients Experience ◽  
The Relationship

One of the many problems cancer patients experience is death anxiety. This descriptive-analytical cross-sectional study aimed to investigate the relationship between authenticity and death anxiety in cancer patients. The participants were 172 cancer patients who referred to medical centers in southeast Iran. The data were collected using authenticity inventory, and death and dying anxiety scale. There was a negative correlation between authenticity and death anxiety, i.e. patients who indicated higher authenticity scores showed lower levels of death anxiety. It seems that developing a comprehensive care program for increasing awareness of authenticity in patients, may be effective in reducing patient death anxiety.

scholarly journals Association of Metabolic Syndrome and Cardiovascular Risk Factors Among Colorectal Cancer Patients Attending in Tikur Anbessa Specialized Hospital Oncology Units: A Comparative Cross-sectional Study June, 2017 Addis Ababa, Ethiopia

2020 ◽  
Author(s):  
Shimelis Adugna Elemo ◽  
Bereket Mihretu Awoke
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cancer Patients ◽  
Addis Ababa ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Colorectal Cancer Patients

Abstract Background: Metabolic syndrome and obesity are risk factors for developing type 2 diabetes mellitus and/or cardiovascular disease, especially stroke. Obesity-associated diseases account for a large portion of public health challenges. Among obesity-related disorders, a direct and independent relationship has been ascertained for colorectal cancer. Objective: The aim of this study was to determine the prevalence of metabolic syndrome and other cardiovascular risk factors, including dyslipidemia, hypertension, dietary and exercise practices, tobacco use and body mass index in individual with colorectal cancer patients attending Tikur Anbessa Hospital Oncology department, Addis Ababa.Methods: A comparative cross-sectional study was conducted from February, 2016 to Jun 2017 on 79 patients attending the Oncology clinic at Tikur Anbessa Hospital. Components of metabolic syndrome, including fasting serum glucose, serum triglyceride, serum high density lipoprotein, blood pressure and waist circumference, was measured in all of the patients. In addition, serum total cholesterol, serum low density lipoprotein was measured with 5010 photometers, and information gathered on smoking and other lifestyle practices, including diet and exercise.Result: Of 79 patients, 23 had metabolic syndrome (MS); 58.2% males; mean-age 48.6 years with range (26 to 78) and 41.8 % Female; mean age 44.6 years with range (20 to 78). Among the MS group, 45.6 % had high blood pressure, 26.6 % had increased waist circumference, 67.1% had serum blood glucose level greater than 100 mg/dL, 68.3 % had low high-density lipoprotein cholesterol level, 57 % had increased triglyceride level, and 3.8 % were obese [body mass index (BMI) >30 kg/m2]. 29 % presented 3 criteria of MS. From total colorectal cancer patients 53.2 % had colon cancer, 46.8 % had rectal cancer and 12.7 % had stage I,40.5 % had stage II (IIa,IIb & IIc), 25.3 % had stage III (a,b,c) and 21.5 % had stage IV disease.CONCLUSION: MS is positively associated with adenomas and colorectal cancer. However, there is not enough information in Ethiopia to justify screening in patients with MS. To our knowledge, no previous study has evaluated this association in Ethiopian patients.

Epidemiological study designs and principles of data analysis: A conceptually integrated suite of methods and techniques

2016 ◽  
Author(s):  
Raj S. Bhopal
Keyword(s):  
Risk Factors ◽  
Disease Incidence ◽  
Case Series ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Natural Experiments ◽  
Case Control Studies ◽  
Cross Sectional ◽  
Common Goals ◽  
Study Designs

Epidemiological studies are unified by their common goals and by their basis in defined populations. The case series (or register-based study) includes examination of trends in deaths, cancers, notifiable diseases, and hospitalizations. Case–control studies are analysed by comparing the exposure to risk factors in cases to those in controls. In a population studied at a specific time and place (a cross-sectional study), measurements can be made of disease, the factors which may cause disease, or both simultaneously. Cohort studies produce data on disease incidence and are especially good on associations between risk factors and disease outcomes. Trials compare treated and untreated populations and are used, primarily, for information on effectiveness of health interventions. Natural experiments, including Mendelian randomization studies, may provide causal evidence. The principles for the analysis of all studies are similar. The design and interpretation should be in the context of traditional, systematic, and meta-analytic reviews.

scholarly journals Ischemic Stroke in Patients with Cancer: A Retrospective Cross-Sectional Study

2021 ◽  
Vol 7 (1) ◽  
pp. 54-61
Author(s):  
Anca Motataianu ◽  
Smaranda Maier ◽  
Sebastian Andone ◽  
Laura Barcutean ◽  
Georgiana Serban ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Cancer Patients ◽  
Small Vessel Disease ◽  
Cryptogenic Stroke ◽  
Cross Sectional Study ◽  
Neurological Deficits ◽  
Large Artery ◽  
Cross Sectional

Abstract Introduction An increasing trend of cancer associated stroke has been noticed in the past decade. Objectives To evaluate the risk factors and the incidence of neoplasia in stroke patients. Material and Method A retrospective, observational study was undertaken on 249 patients with stroke and active cancer (SAC) and 1563 patients with stroke without cancer (SWC). The general cardiovascular risk factors, the site of cancer, and the general clinical data were registered and evaluated. According to the “Oxfordshire Community Stroke Project” (OCSP) classification, all patients were classified into the clinical subtypes of stroke. The aetiology of stroke was considered as large-artery atherosclerosis, small vessel disease, cardio-embolic, cryptogenic or other determined cause. Results The severity of neurological deficits at admission were significantly higher in the SAC group (p<0.01). The haemoglobin level was significantly lower, and platelet level and erythrocyte sedimentation rate were significantly higher in the SAC group. Glycaemia, cholesterol and triglycerides levels were significantly higher in the SWC group. The personal history of hypertension was more frequent in the SWC group. In the SAC group, 28.9% had a cryptogenic aetiology, compared to 9.1% in SWC group. Cardio-embolic strokes were more frequent in the SAC group (24%) than the SWC group (19.6%). In the SAC group, 15,6% were diagnosed with cancer during the stroke hospitalization, and 78% of the SAC patients were without metastasis. Conclusions The most frequent aetiologies of stroke in cancer patients were cryptogenic stroke, followed by large-artery atherosclerosis. SAC patients had more severe neurological deficits and worse clinical outcomes than SWC patients. Stroke in cancer patients appears to be more frequently cryptogenic, probably due to cancer associated thrombosis. The association between stroke and cancer is important, especially in stroke of cryptogenic mechanism, even in the presence of traditional cardiovascular risk factors.

scholarly journals Clinical and Therapeutic Characteristics of Cancer Patients in the Southern Region of Saudi Arabia: A Cross-Sectional Study

2021 ◽  
Vol 18 (12) ◽  
pp. 6654
Author(s):  
Hamad S. Alyami ◽  
Abdallah Y. Naser ◽  
Eman Zmaily Dahmash ◽  
Mohammad H. Alyami ◽  
Osamah M. Belali ◽  
...  
Keyword(s):  
Risk Factors ◽  
Saudi Arabia ◽  
Chronic Disease ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Southern Region ◽  
Smoking History ◽  
Sectional Study ◽  
Cross Sectional ◽  
Icu Admission

Aims: Due to the continuous changes in modern lifestyle and the need to explore the effect of these changes on the risk of developing cancer, ongoing research on the epidemiology and characteristics of cancer patients is requested. This study explored the epidemiology of cancer, its characteristics, treatment patterns, and risk factors in the southern region of Saudi Arabia. Methods: A retrospective cross-sectional study was conducted using cancer patients’ medical records at Asir Central Hospital in the southern region of Saudi Arabia. Active patients’ records were extracted between January 2013 and December 2019. Results: A total of 2038 patients were identified during the study period, with a mean age of 60.9 (SD: 19.0) years. The patients had survived with their cancer for a median duration of 4 years (IQR: 2–6). Around 4.6% of the patients required ICU admission with a median period of 9 days (IQR: 5–14.75). The death rate during the study period was 10.9%. Around 20.8% of the cases were metastatic, of which 77.8% were at stage four of metastasis, and 19.7% of the patients were receiving chemotherapy for their disease. The most common types of cancer were malignant neoplasms of digestive organs, comprising 40.8% of the sample. Older age (60 years and above) and using specific chronic disease medications were predictors associated with a higher risk of death due to cancer (p < 0.05). Smoking history, using specific chronic disease medications, and having previous surgery were predictors associated with a higher risk of ICU admission (p < 0.05). Conclusion: Breast, colon, and liver cancers were the most prevalent in the southern region of Saudi Arabia. Several modifiable cancer risk factors were identified. The results of this study should support decision-makers in the initiation of programs for key modifiable risk factors that enhance lifestyle changes and reduce cancer risks.

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