Serum Iso-Agglutinin Titres in Health and in Mental Disease

1939 ◽  
Vol 85 (357) ◽  
pp. 689-695
Author(s):  
John C. Thomas ◽  
E. J. C. Hewitt

We have previously investigated the blood-group distribution in a series of normal persons and mental patients and shown that there is no significant difference between the two groups (Thomas and Hewitt, 1939). As an ancillary procedure in the investigation of any possible differences in the serological make-up of persons suffering from mental disease, we have determined the iso-agglutinin titres in a similar series of normal and mental patients. On prima facie grounds no difference is to be expected, and in the result, no difference was found.

1939 ◽  
Vol 85 (357) ◽  
pp. 667-688 ◽  
Author(s):  
John C. Thomas ◽  
E. J. C. Hewitt

The distribution of the blood-groups in persons suffering from mental disease has been widely investigated, but the literature is full of conflicting statements. It may fairly be taken that no one has yet demonstrated any statistically significant alteration of the blood-group distribution in any other disease, but there have been many claims for variation in mental diseases.


2019 ◽  
Vol 10 (5) ◽  
pp. 37-42
Author(s):  
Ikechukwu Eugene Onah ◽  
Ezinne Veronica Moses ◽  
Ifeyinwa Esther Ugwuoke ◽  
Sabina Chioma Eze ◽  
Jude Ifeanyichukwu Okwor ◽  
...  

Background: The ABO blood group and Rhesus (Rh) factor remain the most important blood group in transfusion medicine. Knowledge of ABO and rhesus blood group distribution within a population is indispensable for transfusion medicine, clinical and marriage counselling. Aims and Objectives: The objectives of this study were to provide data and compare the pattern of ABO and rhesus blood group distribution between a homogenous and a heterogenous population. Material and Methods: Blood was collected from 352 University students representing a heterogenous population and 235 primary school pupils in a local community representing homogenous population. The ABO and rhesus blood groups were determined using white tile and agglutination methods. Results: Among the 352 and 235 individuals studied in UNN and HFNP, blood groups O had the highest frequency with 54.80% and 51.06% respectively while blood group AB had the least frequency of 4.50% and 3.40% in UNN and HFNP respectively. Rhesus positive had the highest frequency of 88.63% and 95.33% while rhesus negative had the frequencies of 11.35% and 4.68% in UNN and HFNP respectively. Rhesus negative was highest among females in UNN 26 (7.37%) while males had the highest rhesus negative 7 (2.98%) in HFNP. In both study populations, there was no significant difference in ABO and rhesus blood group distribution between the males and females (P > 0.05). Conclusions: A homogenous population is associated with low prevalence of rhesus negative compared to a heterogenous population.


1963 ◽  
Vol 09 (02) ◽  
pp. 472-474 ◽  
Author(s):  
W Dick ◽  
W Schneider ◽  
K Brockmüller ◽  
W Mayer

SummaryA comparison between the repartition of the blood groups in 461 patients suffering from thromboembolic disorders and the normal distribution has shown a statistically ascertained predominance of the group A1. On the other hand the blood groups 0 and A2 are distinctly less frequent than in the normal distribution.


Author(s):  
Sudheer Singh ◽  
Shailesh Kumar Mishra ◽  
Shivani Kalhan ◽  
Puja Sharma ◽  
Rahul N Satarkar ◽  
...  

Viruses ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 416
Author(s):  
Robert Creutznacher ◽  
Thorben Maass ◽  
Patrick Ogrissek ◽  
Georg Wallmann ◽  
Clara Feldmann ◽  
...  

Glycan–protein interactions are highly specific yet transient, rendering glycans ideal recognition signals in a variety of biological processes. In human norovirus (HuNoV) infection, histo-blood group antigens (HBGAs) play an essential but poorly understood role. For murine norovirus infection (MNV), sialylated glycolipids or glycoproteins appear to be important. It has also been suggested that HuNoV capsid proteins bind to sialylated ganglioside head groups. Here, we study the binding of HBGAs and sialoglycans to HuNoV and MNV capsid proteins using NMR experiments. Surprisingly, the experiments show that none of the norovirus P-domains bind to sialoglycans. Notably, MNV P-domains do not bind to any of the glycans studied, and MNV-1 infection of cells deficient in surface sialoglycans shows no significant difference compared to cells expressing respective glycans. These findings redefine glycan recognition by noroviruses, challenging present models of infection.


2016 ◽  
Vol 117 ◽  
pp. S107-S108
Author(s):  
Tuğba Kula Ati̇k ◽  
Bayhan Bektöre ◽  
Ercan Yeni̇lmez ◽  
Mustafa Aparci̇ ◽  
Rıza Aytaç Çeti̇nkaya

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Ali Sabir ◽  
Arslan Iftikhar ◽  
Muhammad Umar Ijaz ◽  
Ghulam Hussain ◽  
Azhar Rasul ◽  
...  

Abstract Objective The current study aimed to investigate the ABO and rhesus (Rh) blood group frequency in the people of District Faisalabad and Sheikhupura, Punjab Province, Pakistan. The retrospective study was conducted on more than thirty thousand people including both male and female patients admitted to the Tehsil Headquarter Hospital, Safdarabad and The Best Hospital, Faisalabad. Blood samples were taken from each subject and subsequently ABO and Rh blood groups were evaluated separately. The antigen antibody agglutination slide test for blood grouping (ABO) and Rh were used to assess the blood group frequencies. Results The frequencies of ABO blood group distribution indicated that blood group B was predominant in the people of Safdarabad followed by O, A and AB respectively. While, among people of Faisalabad, blood group O was predominant followed B, A and AB respectively. Rh negative phenotype was found lesser distributed as compared to the positive Rh phenotype.


2000 ◽  
Vol 6 (1) ◽  
pp. 156-158
Author(s):  
T. Pramanik ◽  
S. Pramanik

The frequencies of ABO and rhesus blood groups vary from one population to another. We studied blood group distribution in 120 Nepalese students; 34% were blood group A, 29% group B, 4% group AB and 32.5% group O. The frequency of Rh-negative blood was 3.33% and Rh-positive 96.66%


2021 ◽  
Vol 8 (12) ◽  
pp. 673-676
Author(s):  
Arzu İrvem ◽  
Abdurrahman Sarmış ◽  
Özlem Akgün Doğan ◽  
Jale Yıldız ◽  
Zafer Habib ◽  
...  

Objective: COVID-19 has been detected in Turkey since March 11, 2020. Istanbul has become an important center of the pandemic in Turkey. Various risk factors for COVID-19 infection, mortality, and morbidity are under investigation. Recent studies have suggested that certain blood groups are risk factors for the disease. The aim of this study is the evaluation the relationship between blood groups and the risk of contracting COVID-19 disease, clinical severity of the disease, and CT (computed tomography) imaging findings. Material and Methods: Age, gender, blood group data, clinical severity and CT images of 300 patients who were positive with RT PCR (Reverse transcription-polymerase chain reaction) and were followed up in the clinic were retrospectively scanned and recorded. The clinical severity of the disease and CT imaging findings were scored, and the data were evaluated statistically. Results: While the incidence of COVID-19 was high in the A blood group, it was low in the 0 blood group. Although there was no significant difference between blood types and clinical severity, the involvement in the B blood group was more severe on CT imaging. Conclusion: People with A blood group should pay more attention to protection and isolation. Investigating this difference and underlying pathogenic mechanisms can guide science with advanced studies.


PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249252
Author(s):  
Reaz Mahmud ◽  
Mohammad Aftab Rassel ◽  
Farhana Binte Monayem ◽  
S. K. Jakaria Been Sayeed ◽  
Md Shahidul Islam ◽  
...  

Background Globally, studies have shown conflicting results regarding the association of blood groups with SARS CoV-2 infection. Objective To observe the association between ABO blood groups and the presentation and outcomes of confirmed COVID-19 cases. Design, setting, and participants This was a prospective cohort study of patients with mild-to-moderately severe COVID-19 infections who presented in the COVID-19 unit of Dhaka Medical College Hospital and were enrolled between 01 June and 25 August, 2020. Patients were followed up for at least 30 days after disease onset. We grouped participants with A-positive and A-negative blood groups into group I and participants with other blood groups into group II. Results The cohort included 438 patients; 52 patients were lost to follow-up, five died, and 381 completed the study. The prevalence of blood group A [144 (32.9%)] was significantly higher among COVID-19 patients than in the general population (p < 0.001). The presenting age [mean (SD)] of group I [42.1 (14.5)] was higher than that of group II [38.8 (12.4), p = 0.014]. Sex (p = 0.23) and co-morbidity (hypertension, p = 0.34; diabetes, p = 0.13) did not differ between the patients in groups I and II. No differences were observed regarding important presenting symptoms, including fever (p = 0.72), cough (p = 0.69), and respiratory distress (p = 0.09). There was no significant difference in the median duration of symptoms in the two group (12 days), and conversion to the next level of severity was observed in 26 (20.6%) and 36 patients (13.8%) in group I and II, respectively. However, persistent positivity of RT-PCR at 14 days of initial positivity was more frequent among the patients in group I [24 (19%)] than among those in group II [29 (11.1%)]. Conclusions The prevalence of blood group A was higher among COVID-19 patients. Although ABO blood groups were not associated with the presentation or recovery period of COVID-19, patients with blood group A had delayed seroconversion.


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