The Pitressin Diagnosis of Idiopathic Epilepsy

1943 ◽  
Vol 89 (375) ◽  
pp. 284-288 ◽  
Author(s):  
William Blyth
Keyword(s):  
Rapid Diagnosis ◽  
Idiopathic Epilepsy ◽  
Definite Diagnosis ◽  
Average Hospital ◽  
Hospital Practice ◽  
Hospital Case ◽  
Degree Of Certainty ◽  
Prolonged Observation ◽  
Made In

As a rule, in hospital practice there’ is little urgency for a rapid diagnosis in idiopathic epilepsy to be effected, and doubtful cases can be submitted to prolonged observation until an actual seizure has resulted. There are, however, certain occasions when the necessity arises for the establishment of a definite diagnosis as early as possible. In the average hospital case, the period of observation necessary will be a matter of days or, at the most, a week or so, but in cases of irregular seizures at infrequent intervals, this period may have to be extended into months before any opinion can be offered. It is with a view to curtailing this period of observation that an attempt has been made in this investigation to determine a method whereby the condition can be diagnosed with a degree of certainty in the absence of seizures.

scholarly journals Progress toward developing a practical societal response to severe convection (2005 EGU Sergei Soloviev Medal Lecture)

2005 ◽  
Vol 5 (5) ◽  
pp. 691-702 ◽  
Author(s):  
C. A. Doswell
Keyword(s):  
Convective Storms ◽  
Temporal Specificity ◽  
Severe Convection ◽  
Societal Response ◽  
Critical Issues ◽  
The Usa ◽  
Degree Of Certainty ◽  
Funding Support ◽  
Spatio Temporal ◽  
Made In

Abstract. A review of severe convection in the context of geophysical hazards is given. Societal responses to geophysical hazards depend, in part, on the ability to forecast the events and the degree of certainty with which forecasts can be made. In particular, the spatio-temporal specificity and lead time of those forecasts are critical issues. However, societal responses to geophysical hazards are not only dependent on forecasting. Even perfect forecasts might not be sufficient for a meaningful societal response without the development of considerable infrastructure to allow a society to respond properly and in time to mitigate the hazard. Geophysical hazards of extreme magnitude are rare events, a fact that tends to make funding support for appropriate preparations difficult to obtain. Focusing on tornadoes as a prototypical hazard from severe convective storms, the infrastructure for dealing with them in the USA is reviewed. Worldwide implications of the experience with severe convective storms in the USA are discussed, with an emphasis on its relevance to the situation in Europe.

scholarly journals Rapid Diagnosis of Mumps Virus Infections by Immunofluorescence Methods

1975 ◽  
Vol 2 (2) ◽  
pp. 81-84
Author(s):  
David A. Lennette ◽  
Richard W. Emmons ◽  
Edwin H. Lennette
Keyword(s):  
Rapid Diagnosis ◽  
Mumps Virus ◽  
Diagnostic Methods ◽  
Direct Immunofluorescence ◽  
Virus Infections ◽  
Standard Methods ◽  
Specific Diagnosis ◽  
Clinical Specimens ◽  
Important Disease ◽  
Made In

Mumps and its complications, particularly meningoencephalitis, is an important disease problem, and more rapid diagnostic methods are desirable. A study was made of immunofluorescence methods for the early detection of mumps virus isolated in cell cultures, or adsorbed directly from clinical specimens onto guinea pig erythrocytes. A specific diagnosis could be made in hours to 2 or 3 days utilizing immunofluorescence methods, in contrast to about 6 days by standard methods. Details of the direct immunofluorescence methods are presented, to encourage wider application in clinical virology laboratories.

COMPARATIVE STUDY OF LITHOTRIPSY AND MINIPERC IN 11 TO 18 MM IMPACTED PUJ CALCULI

2018 ◽  
Vol 4 (3) ◽  
pp. 30-34
Author(s):  
Narendra Wankhade ◽  
Atul Khalkar ◽  
Suhas Ghule Ghule ◽  
Hemant Naik
Keyword(s):  
Stone Disease ◽  
Medium Size ◽  
Multicentric Study ◽  
Average Hospital ◽  
X Ray ◽  
Long Term Follow Up ◽  
Group 2 ◽  
Made In

Background: Impacted PUJ calculi are well known entity.  Nephrolithiasis is a common disorder that accounts for significant cost, morbidity, and loss of work. Over last 3 decades considerable advances have been made in the management of kidney stone disease, still there is no single universally accepted and uniformly effective modality of treatment in medium size of impacted PUJ calculi. Aim: To study the efficacy of lithotripsy and MINIPERC in 11mm to 18mm impacted PUJ calculi. Methodology: The patients with impacted PUJ calculi of size 11 to 18mm of both sexes of all age group varying form 18-60 years, on consecutive sampling method total 84 patients were included. All patients underwent basic lab investigations, USG, IVU and investigations for fitness purpose. Group 1: All procedures were tubeless.  We used 15 Fr Richard Wolf nephroscope for the procedure. 16 to 20 Fr Amplatz sheath was used depending upon situation. Fragmentation was performed using pneumatic lithoclast or holmium Laser depending upon stone size and characteristics. Group 2: Underwent DJ stenting under subarachnoid block or short GA depending upon situation. On the next day they were subjected for lithotripsy on Dorniel alpha machine under USG guidance, 3000 shocks were given in each sitting. One to three such sittings were given. Post operatively ultrasonography and X-ray KUB was done in all the patients and stents were removed after assuring complete clearance. Patients with absence of stone or presence of stone less than 4 mm on USG or x-ray KUB were declared as completely cleared. Results: Average hospital stay was 48 hours in miniperc group and it was 30 hours in DJ with ESWL group. Clearance rate was 100 % in Miniperc group and it was 85.71 % in DJ with ESWL group. Five patients (11.9%) in DJ lithotripsy group required another procedure. (Two needed miniperc and three needed URS). Two(4.76 %) patients in miniperc group had fever in post op period but nobody suffered major sepsis. Conclusion: Miniperc fulfils many criteria if we see results and complications. Although bigger sized multicentric study and long term follow up is needed. 

Hypnosis in Mental Hospital Practice

1937 ◽  
Vol 83 (344) ◽  
pp. 316-329 ◽  
Author(s):  
C. L. Copeland ◽  
E. Howard Kitching
Keyword(s):  
Large Class ◽  
Medical Staff ◽  
Mental Hospital ◽  
Orthodox Medicine ◽  
Hospital Practice ◽  
Mental Treatment ◽  
Made In ◽  
Heterogeneous Class

The Mental Treatment Act of 1930 has brought within the purview of the mental hospital that large class of psychoneurotic and “early psychotic” patients who formerly drifted despairingly in the wilderness between orthodox medicine and the quack. The purpose of this paper is to show how an attempt is being made in this hospital to deal with this heterogeneous class of patients by means of psychotherapy, carried out by the ordinary medical staff of the hospital, without interference with their routine duties.

TULAREMIA AS A PEDIATRIC PROBLEM

PEDIATRICS ◽  
1950 ◽  
Vol 6 (1) ◽  
pp. 113-123
Author(s):  
HAROLD B. LEVY ◽  
CLARENCE H. WEBB ◽  
JACQUES D. WILKINSON
Keyword(s):  
Early Diagnosis ◽  
Clinical Feature ◽  
Average Hospital ◽  
Retrospective Diagnosis ◽  
Strong Point ◽  
Early Appearance ◽  
Animal Contact ◽  
High Index Of Suspicion ◽  
Usual Laboratory ◽  
Made In

The results obtained, it would appear that the lack of any pathognomonic clinical feature, tardy appearance of specific agglutinins, and variations from the typical adult course render imperative a high index of suspicion if an early diagnosis of tularemia is to be made in a child. Careful questioning concerning possible ingestion of infected meats, animal contact or tick bite must be stressed. Involvement of siblings may be a strong point in favor of ingestional tularemia. Painstaking search for a local lesion should be made in every case with unexplained adenitis or appearance of sepsis; the frequency of pharyngo-tonsillar involvement must be appreciated. Usual laboratory aids may be of little value in early diagnosis in the average hospital or office at the present time. Early appearance of the heterophile cross-agglutination reaction may alert the observer to the possibility of tularemic infection. A severely ill patient, for whom a definitive diagnosis cannot be reached, failing to respond to therapy for other suspected illnesses, and in whom any of the factors just mentioned prevail, should receive the benefit of a therapeutic test with streptomycin. Favorable response and survival, as is true of effective antibiotic therapy for other acute illnesses, may permit of later retrospective diagnosis in some whose illnesses or deaths would otherwise have remained unexplained.

Spectrophotometric measurements of objective-prism spectra

1966 ◽  
Vol 24 ◽  
pp. 118-119
Author(s):  
Th. Schmidt-Kaler
Keyword(s):  
Progress Report ◽  
Two Dimensional ◽  
Objective Prism ◽  
Made In

I should like to give you a very condensed progress report on some spectrophotometric measurements of objective-prism spectra made in collaboration with H. Leicher at Bonn. The procedure used is almost completely automatic. The measurements are made with the help of a semi-automatic fully digitized registering microphotometer constructed by Hög-Hamburg. The reductions are carried out with the aid of a number of interconnected programmes written for the computer IBM 7090, beginning with the output of the photometer in the form of punched cards and ending with the printing-out of the final two-dimensional classifications.

Surface Structure in Microtomed Sections Caused by Glass and Diamond Knives

1971 ◽  
Vol 29 ◽  
pp. 456-457
Author(s):  
J. Temple Black ◽  
William G. Boldosser
Keyword(s):  
Plastic Deformation ◽  
Epoxy Resin ◽  
Carbon Coating ◽  
Surface Damage ◽  
Body Angle ◽  
Normal Manner ◽  
Bottom Side ◽  
Cutting Direction ◽  
Made In ◽  
Diamond Knife

Ultramicrotomy produces plastic deformation in the surfaces of microtomed TEM specimens which can not generally be observed unless special preparations are made. In this study, a typical biological composite of tissue (infundibular thoracic attachment) infiltrated in the normal manner with an embedding epoxy resin (Epon 812 in a 60/40 mixture) was microtomed with glass and diamond knives, both with 45 degree body angle. Sectioning was done in Portor Blum Mt-2 and Mt-1 microtomes. Sections were collected on formvar coated grids so that both the top side and the bottom side of the sections could be examined. Sections were then placed in a vacuum evaporator and self-shadowed with carbon. Some were chromium shadowed at a 30 degree angle. The sections were then examined in a Phillips 300 TEM at 60kv.Carbon coating (C) or carbon coating with chrom shadowing (C-Ch) makes in effect, single stage replicas of the surfaces of the sections and thus allows the damage in the surfaces to be observable in the TEM. Figure 1 (see key to figures) shows the bottom side of a diamond knife section, carbon self-shadowed and chrom shadowed perpendicular to the cutting direction. Very fine knife marks and surface damage can be observed.

Iron storage sites in the myocardium as revealed by cytohistochemistry

1988 ◽  
Vol 46 ◽  
pp. 394-395
Author(s):  
M. Ashraf ◽  
F. Thompson ◽  
S. Miki ◽  
P. Srivastava
Keyword(s):  
Cardiac Tissue ◽  
Coronary Perfusion ◽  
Intracellular Iron ◽  
Ether Anesthesia ◽  
Intense Staining ◽  
Iron Storage ◽  
Thin Sections ◽  
Rat Hearts ◽  
Cacodylate Buffer ◽  
Made In

Iron is believed to play an important role in the pathogenesis of ischemic injury. However, the sources of intracellular iron in myocytes are not yet defined. In this study we have attempted to localize iron at various cellular sites of the cardiac tissue with the ferrocyanide technique.Rat hearts were excised under ether anesthesia. They were fixed with coronary perfusion with 3% buffered glutaraldehyde made in 0.1 M cacodylate buffer pH 7.3. Sections, 60 μm in thickness, were cut on a vibratome and were incubated in the medium containing 500 mg of potassium ferrocyanide in 49.5 ml H2O and 0.5 ml concentrated HC1 for 30 minutes at room temperature. Following rinses in the buffer, tissues were dehydrated in ethanol and embedded in Spurr medium.The examination of thin sections revealed intense staining or reaction product in peroxisomes (Fig. 1).

Solid-phase immunoelectron microscopy for rapid diagnosis of enteroviruses

1984 ◽  
Vol 42 ◽  
pp. 226-227 ◽  
Author(s):  
K. Pegg-Feige ◽  
F. W. Doane
Keyword(s):  
Electron Microscopy ◽  
Cell Culture ◽  
Immunoelectron Microscopy ◽  
Detection Method ◽  
Solid Phase ◽  
Protein A ◽  
Plant Viruses ◽  
Rapid Diagnosis ◽  
Virus Diagnosis ◽  
Antiviral Antibody

Immunoelectron microscopy (IEM) applied to rapid virus diagnosis offers a more sensitive detection method than direct electron microscopy (DEM), and can also be used to serotype viruses. One of several IEM techniques is that introduced by Derrick in 1972, in which antiviral antibody is attached to the support film of an EM specimen grid. Originally developed for plant viruses, it has recently been applied to several animal viruses, especially rotaviruses. We have investigated the use of this solid phase IEM technique (SPIEM) in detecting and identifying enteroviruses (in the form of crude cell culture isolates), and have compared it with a modified “SPIEM-SPA” method in which grids are coated with protein A from Staphylococcus aureus prior to exposure to antiserum.

Microanalysis of precipitates in a ferritic steel

1978 ◽  
Vol 36 (1) ◽  
pp. 618-619
Author(s):  
J.M. Titchmarsh
Keyword(s):  
Ferritic Steel ◽  
Particle Identification ◽  
Energy Dispersive ◽  
Objective Lens ◽  
Ferritic Steels ◽  
Replica Technique ◽  
X Ray ◽  
Large Numbers ◽  
Scanning Transmission ◽  
Made In

The advances in recent years in the microanalytical capabilities of conventional TEM's fitted with probe forming lenses allow much more detailed investigations to be made of the microstructures of complex alloys, such as ferritic steels, than have been possible previously. In particular, the identification of individual precipitate particles with dimensions of a few tens of nanometers in alloys containing high densities of several chemically and crystallographically different precipitate types is feasible. The aim of the investigation described in this paper was to establish a method which allowed individual particle identification to be made in a few seconds so that large numbers of particles could be examined in a few hours.A Philips EM400 microscope, fitted with the scanning transmission (STEM) objective lens pole-pieces and an EDAX energy dispersive X-ray analyser, was used at 120 kV with a thermal W hairpin filament. The precipitates examined were extracted using a standard C replica technique from specimens of a 2¼Cr-lMo ferritic steel in a quenched and tempered condition.

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