scholarly journals Psychiatric characteristics in transsexual individuals: multicentre study in four European countries

2014 ◽  
Vol 204 (2) ◽  
pp. 151-156 ◽  
Author(s):  
Gunter Heylens ◽  
Els Elaut ◽  
Baudewijntje P. C. Kreukels ◽  
Muirne C. S. Paap ◽  
Susanne Cerwenka ◽  
...  

BackgroundResearch into the relationship between gender identity disorder and psychiatric problems has shown contradictory results.AimsTo investigate psychiatric problems in adults fulfilling DSM-IVTR criteria for a diagnosis of gender identity disorder.MethodData were collected within the European Network for the Investigation of Gender Incongruence using the Mini International Neuropsychiatric Interview – Plus and the Structured Clinical Interview for DSM-IV Axis II Disorders (n = 305).ResultsIn 38% of the individuals with gender identity disorder a current DSM-IV-TR Axis I diagnosis was found, mainly affective disorders and anxiety disorders. Furthermore, almost 70% had a current and lifetime diagnosis. All four countries showed a similar prevalence, except for affective and anxiety disorders, and no difference was found between individuals with early-onset and late-onset disorder. An Axis II diagnosis was found in 15% of all individuals with gender identity disorder, which is comparable to the general population.ConclusionsPeople with gender identity disorder show more psychiatric problems than the general population; mostly affective and anxiety problems are found.

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Dragana Duišin ◽  
Borjanka Batinić ◽  
Jasmina Barišić ◽  
Miroslav L. Djordjevic ◽  
Svetlana Vujović ◽  
...  

Background.Investigations in the field of gender identity disorder (GID) have been mostly related to psychiatric comorbidity and severe psychiatric disorders, but have focused less on personality and personality disorders (PDs).Aims.The aim of the study was to assess the presence of PDs in persons with GID as compared to cisgendered (a cisgender person is a person who is content to remain the gender they were assigned at birth) heterosexuals, as well as to biological sex.Methods.The study sample consisted of 30 persons with GID and 30 cisgendered heterosexuals from the general population. The assessment of PDs was conducted by application of the self-administered Structured Clinical Interview for DSM-IV Axis II PDs (SCID-II).Results.Persons with GID compared to cisgender heterosexuals have higher presence of PDs, particularly Paranoid PD, avoidant PDs, and comorbid PDs. In addition, MtF (transwomen are people assigned male at birth who identify as women) persons are characterized by a more severe psychopathological profile.Conclusions.Assessment of PDs in persons with GID is of great importance as it comprises a key part of personalized treatment plan tailoring, as well as a prognostic factor for sex-reassignment surgery (SRS) outcome.


2006 ◽  
Vol 22 (3) ◽  
pp. 207-215 ◽  
Author(s):  
Fons J. Trompenaars ◽  
Erik D. Masthoff ◽  
Guus L. Van Heck ◽  
Paul P. Hodiamont ◽  
Jolanda De Vries

This study scrutinizes the ability of the WHO quality of life assessment instrument (WHOQOL-100) to discriminate (1) between psychiatric outpatients and the general population, and (2) between subgroups of psychiatric outpatients. A sample of Dutch adult psychiatric outpatients (N = 410) completed the WHOQOL-100. In addition, DSM-IV Axis-I and Axis-II diagnoses were obtained. Compared with the general population, psychiatric outpatients scored significantly lower on all aspects of self-reported quality of life (QOL). Within the group of outpatients, participants with DSM-IV diagnoses had lower scores than those without. Participants with diagnoses on both Axis-I and Axis-II of DSM-IV (comorbidity) had the lowest self-reported QOL. It is concluded that in psychiatric outpatients, outcome scores of self-reported QOL were negatively related to presence and degree of psychopathology. The WHOQOL-100 has good discriminant ability for psychiatric outpatients.


2010 ◽  
Vol 12 (1) ◽  
pp. 103-114 ◽  

Genetic epidemiologic studies indicate that all ten personality disorders (PDs) classified on the DSM-IV axis II are modestly to moderately heritable. Shared environmental and nonadditive genetic factors are of minor or no importance. No sex differences have been identified, Multivariate studies suggest that the extensive comorbidity between the PDs can be explained by three common genetic and environmental risk factors. The genetic factors do not reflect the DSM-IV cluster structure, but rather: i) broad vulnerability to PD pathology or negative emotionality; ii) high impulsivity/low agreeableness; and iii) introversion. Common genetic and environmental liability factors contribute to comorbidity between pairs or clusters of axis I and axis II disorders. Molecular genetic studies of PDs, mostly candidate gene association studies, indicate that genes linked to neurotransmitter pathways, especially in the serotonergic and dopaminergic systems, are involved. Future studies, using newer methods like genome-wide association, might take advantage of the use of endophenotypes.


2012 ◽  
Vol 43 (8) ◽  
pp. 1673-1683 ◽  
Author(s):  
K. M. Keyes ◽  
N. R. Eaton ◽  
R. F. Krueger ◽  
A. E. Skodol ◽  
M. M. Wall ◽  
...  

BackgroundDimensional models of co-morbidity have the potential to improve the conceptualization of mental disorders in research and clinical work, yet little is known about how relatively uncommon disorders may fit with more common disorders. The present study estimated the meta-structure of psychopathology in the US general population focusing on the placement of five under-studied disorders sharing features of thought disorder: paranoid, schizoid, avoidant and schizotypal personality disorders, and manic episodes as well as bipolar disorder.MethodData were drawn from the National Epidemiologic Survey on Alcohol and Related Conditions, a face-to-face interview of 34 653 non-institutionalized adults in the US general population. The meta-structure of 16 DSM-IV Axis I and Axis II psychiatric disorders, as assessed by the Alcohol Use Disorder and Associated Disabilities Interview Schedule DSM-IV version (AUDADIS-IV), was examined using exploratory and confirmatory factor analysis.ResultsWe document an empirically derived thought disorder factor that is a subdomain of the internalizing dimension, characterized by schizoid, paranoid, schizotypal and avoidant personality disorders as well as manic episodes. Manic episodes exhibit notable associations with both the distress subdomain of the internalizing dimension as well as the thought disorder subdomain. The structure was replicated for bipolar disorder (I or II) in place of manic episodes.ConclusionsAs our understanding of psychopathological meta-structure expands, incorporation of disorders characterized by detachment and psychoticism grows increasingly important. Disorders characterized by detachment and psychoticism may be well conceptualized, organized and measured as a subdimension of the internalizing spectrum of disorders. Manic episodes and bipolar disorder exhibit substantial co-morbidity across both distress and thought disorder domains of the internalizing dimension. Clinically, these results underscore the potential utility of conceptualizing patient treatment needs using an approach targeting psychopathological systems underlying meta-structural classification rubrics.


2016 ◽  
Vol 209 (4) ◽  
pp. 319-326 ◽  
Author(s):  
Yongsheng Tong ◽  
Michael R. Phillips ◽  
Kenneth R. Conner

BackgroundThere are meagre data on Axis II personality disorders and suicidal behaviour in China.AimsTo describe the prevalence of Axis II personality disorders in suicides and suicide attempts in China and to estimate risk for these outcomes associated with personality disorders.MethodPeople who died by suicide (n = 151), people who attempted suicide (n = 118) and living community controls (n = 140) were randomly sampled from four Chinese counties and studied using the Structured Clinical Interviews for DSM-IV-TR Axis I Disorders (SCID-I) and Axis II Personality Disorders (SCID-II). We also determined the prevalence of subthreshold versions of ten DSM-IV personality disorders.ResultsAxis II personality disorders were present in 7% of the suicide group, 6% of the suicide attempt group and 1% of the control group. Threshold and subthreshold personality disorders had adjusted odds ratios (point estimates) in the range of 2.7–8.0 for suicide and for suicide attempts.ConclusionsAxis II personality disorders may confer increased risk for suicidal behaviour in China, but their low prevalence in the community and among people with suicidal behaviour suggests that other personality constructs such as select dimensional traits may be a more fruitful avenue for understanding and preventing suicide in China.


2008 ◽  
Vol 103 (1) ◽  
pp. 173-188
Author(s):  
Tali Nachshoni ◽  
Yehuda Abramovitch ◽  
Vladimir Lerner ◽  
Miriam Assael-Amir ◽  
Moshe Kotler ◽  
...  

There is limited information on mental health of psychologists and social workers despite their rendering mental health services, so their subjective perception of mental disorder was explored via a self-evaluation survey in which they self-diagnosed the presence of DSM-IV disorders within themselves. The sample of 128 professionals included 63 psychologists and 65 social workers. The presence of Axis I traits was reported by 81.2%, the three most frequent traits being mood, obsessive-compulsive disorder, and eating disorder. Axis II traits were reported by 73.4% of subjects, the three most frequent conditions being narcissistic, avoidant, and obsessive-compulsive personality traits. While a high percentage of subjects reported the presence of either an Axis I or Axis II disorder, the average severity reported was low. More psychologists reported on mood, social phobia, and eating problems than social workers, while the latter reported more on psychotic problems. Psychologists reported more Axis II traits, especially paranoid, narcissistic, and avoidant subtypes. More women than men reported eating problems, while more men reported schizoid and avoidant personality traits. In conclusion, manifestations of subthreshold psychiatric conditions were prominently reported. These findings suggest encouraging mental health care professionals to explore treatment for problems if present.


2011 ◽  
Vol 120 (1) ◽  
pp. 198-209 ◽  
Author(s):  
Espen Røysamb ◽  
Kenneth S. Kendler ◽  
Kristian Tambs ◽  
Ragnhild E. Ørstavik ◽  
Michael C. Neale ◽  
...  
Keyword(s):  
Axis Ii ◽  
Axis I ◽  

Author(s):  
Mark A. Whisman ◽  
Daniel BE

Depression often co-occurs with other Axis I and Axis II psychiatric disorders. This chapter presents a model for how cognitive therapy (CT) of depression can be adapted in conceptualizing and treating the complex set of issues and problems that often accompany comorbid depression. It begins with a discussion of the prevalence of comorbidity in community and clinical samples, then review the research on comorbidity and outcome to CT for depression, followed by a model for adapting or modifying CT for patients who present with depression and a comorbid Axis I or Axis II disorder. The chapter concludes with specific clinical guidelines for treating depression that co-occurs with anxiety disorders, substance use disorders, and personality disorders.


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