Usefulness of frailty markers in the assessment of the health and functional status in older cancer patient referred for chemotherapy

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 19673-19673 ◽  
Author(s):  
F. G. Retornaz ◽  
J. Monette ◽  
M. Monette ◽  
N. Sourial ◽  
D. Wan-Chow-Wah ◽  
...  

19673 Background: In order to properly support clinical decisions, geriatric assessment (GA) is recommended for older cancer patients. However, the best form of GA remained unknown and recent studies demonstrated that usual GA tools may have a ceiling effect in detecting adverse outcomes to cancer treatment. Frailty has emerged as a concept characterizing cumulative declines across multiple physiologic systems, leading to increased vulnerability and risk of adverse outcomes. Consequently, the concept of frailty may represent a more sensitive way to better characterize health and functional status and to detect potential vulnerability to adverse outcomes in older cancer patients. The purpose of this pilot study was to explore the usefulness of frailty markers in older cancer patients. Methods: This cross- sectional study included 50 cancer patients, (70 years and older) referred to an oncology clinic for chemotherapy. Chronic diseases, IADL and ADL disabilities, and seven domains considered as frailty markers (nutrition, mobility, strength, energy, physical activities, mood and cognition) were assessed. Patients were classified into hierarchical groups based on the results of their assessment. Results: While 15 (30%) patients had at least one disability in IADL and 8 (16%) patients had at least one disability in ADL, 27 patients (54 %) were completely independent for IADL and ADL. Among those patients with no IADL nor ADL disability, 21 patients (42%) presented at least one frailty marker. In the whole cohort, 44 patients (88%) had at least one frailty markers. The most prevalent of the frailty markers were nutrition, mobility and physical activity (respectively 62%, 58% and 42%). Conclusion: Markers of frailty add substantial information to the usual GA tools in detecting potential vulnerability in older cancer patients. Additional studies are needed to determine if the addition of the frailty markers to the usual GA tools can help to better characterize the older cancer population and predict risk of toxicities and adverse outcomes due to cancer treatment. No significant financial relationships to disclose.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 1525-1525
Author(s):  
John Panzone ◽  
Christopher Welch ◽  
Ruben Pinkhasov ◽  
Joseph M Jacob ◽  
Oleg Shapiro ◽  
...  

1525 Background: Studies show that cancer patients and survivors are likely to endure financial toxicity long after being diagnosed. Methods: To examine the influence of race on financial toxicity among individuals with a history of cancer, a US based cross sectional study was conducted using data on 1,328 cancer patients collected from the Health Information National Trends Survey. Multivariable logistic regression analyses were used to analyze the relationship between race and financial toxicity, adjusting for known confounders. Results: Blacks, Hispanics and other races were shown to have a lower rate of insurance compared to Whites. Whites were also more likely to receive cancer treatment than other races (6.1% received no treatment vs 15.0% of Blacks, 17.8% of Hispanics, and 9.7% of other races, p<0.001). Considerably more Whites underwent surgical treatment of their cancer (77%) vs. 60% of Blacks, 55% of Hispanics and 74.2% of other races, p<0.001. Blacks were found to be over 5 times more likely to be denied insurance (OR 5.003, 95% CI 2.451-10.213, p<0.001) and more than twice as likely to be hurt financially than Whites (OR 2.448, 95% CI 1.520-3.941, p<0.001). Other racial minorities were also more than twice as likely to be hurt financially than Whites (OR 2.421, 95% CI 1.248-4.698, p=0.009) (Table). Conclusions: These data suggest that race is significantly associated with increased rates of being hurt financially and being denied insurance due to cancer. Awareness of race inequality should be raised so that equal cancer treatment can be provided, irrespective of race, gender or socioeconomic status.[Table: see text]


2021 ◽  
Vol 27 ◽  
Author(s):  
Luz Alejandra Lorca ◽  
Cinara Sacomori ◽  
Rodrigo Vidal-Labra ◽  
Nathalie Paloma Cavieres ◽  
Kamilla Zomkowski

Author(s):  
Maisa Vitória Gayoso ◽  
Marla Andréia Garcia de Avila ◽  
Thays Antunes da Silva ◽  
Rúbia Aguiar Alencar

ABSTRACT Objective: To verify the association between the level of comfort of the caregiver and socio-demographic variables related to caregiving, and the patient’s functional status and symptoms. Method: Cross-sectional study with non-probabilistic intentional sample. The instruments Palliative Performance Scale (score 0 to 100%), Edmonton Symptom Assessment Scale (symptom scores from zero to ten) and Holistic Comfort Questionnaire (total score ranging from 49 to 294 and mean score from 1 to 6) were used. The relationship between comfort scores and independent variables was calculated by multiple linear regression. Results: Fifty informal caregivers participated in the study - 80% were female, 32% were 60 years old or older, 36% were children of the patient, 58% had paid work and 60% did not have help in the care. The mean overall comfort was 4.52 points. A better functional status of the patients was associated with higher levels of comfort of the caregivers. Older caregivers who received helped in the care activities presented higher comfort scores. Conclusion: The level of comfort of caregivers of cancer patients receiving palliative care was associated with socio-demographic variables and patients’ functional status and symptoms.


2021 ◽  
Author(s):  
Yichao Wang ◽  
Geliang Yang ◽  
Zhan Gu ◽  
Chengyan Wang ◽  
Huiqing Zhang ◽  
...  

Abstract Background With the rapid spread of COVID-19 worldwide, the clinical practice in cancer treatment of complementary and alternative medicine (CAM) becomes significantly different. This study was designed to explore the changes of China’s cancer patients’ perception, attitude and clinical practice in CAM after the pandemic of COVID-19. Methods A multicenter before-after cross-sectional study was conducted, including 448 cancer patients by a survey. Results For perception, half of the cancer patients (51.2%) reported they had received adequate information in CAM cancer treatment and had a great expectation in medical appointment pattern (40.2%). For attitudes, most of the cancer patients (79.4%) had full of confidence in CAM cancer treatment and showed a strong desire to learn more about CAM (70.2%). Nearly half of the cancer patients (44.0%) presented their oncology clinics had been greatly affected by COVID-19, however, most (82.8%) refused to the online medical service pattern. For clinical practice, Chinese herbal medicine was widely used before (89.5%) / after (90.3%) the epidemic of COVID-19 and the main purpose of receiving CAM therapy was to improve immune system (71.8%). The frequency of patients’ visiting the clinic decreased significantly (P < 0.001), and most (90.0%) didn’t change their follow-up pattern. The majority of the cancer patients (83.3%) were identified as CAM users and the only predictive factor was national health insurance in the multivariable logistic regression model. Conclusion China’s cancer patients show more interest and confidence in treating cancer by CAM, and the new medical pattern such as medical appointment, has been gradually accepted during the COVID-19 pandemic. However, the cancer patients’ perception in CAM and online medical service pattern still need to be improved.


2021 ◽  
Author(s):  
Yichao Wang ◽  
Geliang Yang ◽  
Zhan Gu ◽  
Chengyan Wang ◽  
Huiqing Zhang ◽  
...  

Abstract Background: With the rapid spread of COVID-19 worldwide, the clinical practice in cancer treatment of complementary and alternative medicine (CAM) becomes significantly different. This study was designed to explore the changes of China’s cancer patients’ perception, attitude and clinical practice in CAM after the pandemic of COVID-19. Methods: A multicenter before-after cross-sectional study was conducted, including 448 cancer patients by a survey. Results: For perception, half of the cancer patients (51.2%) reported they had received adequate information in CAM cancer treatment and had a great expectation in medical appointment pattern (40.2%). For attitudes, most of the cancer patients (79.4%) had full of confidence in CAM cancer treatment and showed a strong desire to learn more about CAM (70.2%). Nearly half of the cancer patients (44.0%) presented their oncology clinics had been greatly affected by COVID-19, however, most (82.8%) refused to the online medical service pattern. For clinical practice, Chinese herbal medicine was widely used before (89.5%) / after (90.3%) the epidemic of COVID-19 and the main purpose of receiving CAM therapy was to improve immune system (71.8%). The frequency of patients’ visiting the clinic decreased significantly (P < 0.001), and most (90.0%) didn’t change their follow-up pattern. The majority of the cancer patients (83.3%) were identified as CAM users and the only predictive factor was national health insurance in the multivariable logistic regression model. Conclusion: China’s cancer patients show more interest and confidence in treating cancer by CAM, and the new medical pattern such as medical appointment, has been gradually accepted during the COVID-19 pandemic. However, the cancer patients’ perception in CAM and online medical service pattern still need to be improved.


2012 ◽  
Vol 6 (5) ◽  
Author(s):  
Samantha Yee ◽  
Esme Fuller-Thomson ◽  
Catherine Dwyer ◽  
Ellen Greenblatt ◽  
Heather Shapiro

Introduction: The purpose of this cross-sectional study was toexplore factors associated with oncology patients’ decision to banksperm prior to cancer treatment.Materials andMethods: Patients who were referred to the oncologysperm banking program between January 2009 and March 2010 were invited to complete an 18-item questionnaire during one oftheir sperm banking visits.Results: Of the 157 cancer patients referred to the Mount Sinai Oncology Sperm and Tissue Bank for sperm banking during the15-month period, 79 questionnaires were returned (50% response rate). Of the respondents, 89% were informed about sperm bankingby their physician. Future family planning was cited as the mainreason to bank. Cost was not a barrier for the vast majority ofrespondents. Forty percent of respondents banked sperm within 4days prior to initiating cancer treatment. Most respondents reliedon their physician for verbal information on sperm banking. Eighty-one percent were unaware of any patient organizations that have educational materials on oncology fertility preservation.Conclusion: Sperm banking prior to cancer treatment is the only proven method of preserving fertility for cancer patients. The two main determinants associated with deciding whether to bank sperm were: the physician’s recommendation and the patient’s desirefor future fatherhood. Physicians play a key role in influencing patients’ decisions. The recommendation to bank sperm is a persuasive message if patients are clearly informed about their potential risk of infertility post-cancer treatment, and that sperm banking is an effective way of preserving fertility. Providing patients with education materials might enhance compliance in sperm banking.


Author(s):  
Sushil Gour ◽  
Rajesh Kumar Maurya ◽  
Punya Pratap Singh ◽  
Vrashbhan Ahirwar ◽  
Mahendra Dhakar ◽  
...  

Background: A cancer diagnosis can have a significant impact on mental health and wellbeing. Cancer is the second most common cause of death after heart diseases and it accounted for 9.6 million deaths worldwide in 2018. Various individual psychosocial and contextual factors potentially contribute to the development of anxiety and depression among people with cancer. In comparison with general people, the prevalence of anxiety and depression is frequently found to be higher among cancer patient, but estimates vary due to various factors, such as the type of cancer, treatment setting, and prognosis of disease. The present study was conducted to find out the estimate of depression in cancer patients undergoing chemotherapy and determine the various factors associated with depression.Methods: A cross-sectional study was conducted amongst cancer patients undergoing chemotherapy at Department of Oncology, Government Bundelkhand Medical College and Hospital, Sagar from January to April 2019. 150 participants were interviewed using predesigned questionnaire based on the Beck’s depression inventory.Results: Out of 150 cancer patients, 83 (55.3%) were found to be depressed. Depression was comparatively higher in patients’ ≥50 years; in males. Among the study patients, 83 (55.33%) had depression of which 21 (25.3%) had borderline clinical depression, 54 (65.06%) had moderate depression and 08 (9.6%) had severe depression.Conclusions: The study revealed depression in majority of patients receiving chemotherapy. Treatment of cancer patients need to be complemented by psychological support. Research is urgently needed into the possible impacts of long term effects of cancer treatment on mental health.


2020 ◽  
Vol 66 (10) ◽  
pp. 1423-1430
Author(s):  
José Klerton Luz Araújo ◽  
Leandro Marques da Silva ◽  
Camila Alencar Santos ◽  
Izabelle da Silva Oliveira ◽  
Gabriela Medrado Fialho ◽  
...  

SUMMARY INTRODUCTION: Cancer patients and their caregivers incur costs not covered by the Sistema Único de Saúde – SUS(Unified Health System) during their treatment, with expenses related to transportation, symptomatic medications, food, loss of working days, and others. OBJECTIVE: To evaluate the costs incurred and not covered for cancer patients and their caregivers during cancer treatment at SUS. METHODS: This is a cross-sectional study of 110 cancer patients undergoing chemotherapy, radiotherapy, and 88 caregivers in the last month prior to their inclusion in the study. We correlated costs with clinical and sociodemographic variables such as gender, race, age, marital status, education, occupation, place of birth, origin, monthly income, family income, housing, comorbidities, types of cancer, and staging. RESULTS: We observed that the average cost for study patients was R$ 747.92, which corresponds to 78.4% of the minimum wage, and the average cost for caregivers was R$ 118.86, which is 12.46% of the minimum wage. Among all variables analyzed, the average overall monthly cost for patients was positively correlated with the occupation (p = 0.021) and origin (p = 0.038) variables. For the other variables, no significant associations were detected. CONCLUSION: The positive correlation found between occupation and origin variables with costs incurred and not covered for patients suggests that the creation of programs that enable the payment of costs not covered by SUS and the decentralization of access to cancer treatment could potentially facilitate patients' adherence to cancer treatment.


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