Perceptions on the effect of physical activity on quality of life, overall survival, and fatigue in palliative cancer patients.
198 Background: Physical activity is an important lifestyle recommendation for all patients’ wellbeing. With better cancer treatments and palliative patients living longer, maintaining physical activity is becoming an important survivorship goal, even in the palliative setting. We assessed cancer patient’s perception of the effect of physical activity on their quality of life, overall survival, and fatigue. Methods: In a cross-sectional survey across all cancer sites, patient perception of the effect of physical activity on three outcomes: quality of life, overall survival, and fatigue. Palliative status was determined by chart review and primary oncologist assessments. Regression-based estimates of the odds ratios and confidence intervals (CI) described any differences in perception between palliative and non-palliative patients. Results: Of 1283 patients recruited, 1080 completed the entire survey; median (range) age was 58 (18-98) years; 54% were female; 15% were palliative. Palliative patients were less likely than non-palliative patients to believe that physical activity improved overall survival, with an odds ratio of 0.53 (95%CI 0.34-0.83; P = 0.006). Palliative patients were less likely to perceive that physical activity improved fatigue, with odds ratio 0.68 (95%CI: 0.47-0.97; P = 0.04). Although not statistically significant, palliative patients also perceived less of a positive effect of physical activity on quality of life with an odds ratio of 0.65 (95% CI 0.47-0.97; P = 0.12). Results were similar regardless of whether patients were asked to perceive the effect of physical activity on themselves or in the general cancer patient. Conclusions: Palliative patients were more likely to believe that physical activity did not improve their overall survival and fatigue compared to the curative counterparts. Also, there was no significant difference in the perception of the effect of physical activity on the quality of life among the two groups of cancer survivors. Since palliative patients are living longer, future research can focus on implementing exercise recommendations and following up so the actual benefits can be seen.